Methods for diagnosing and treating inflammatory bowel disease

MA39804AUndetermined Publication Date: 2017-02-01F HOFFMANN LA ROCHE & CO AG +1

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Patent Information

Application Number: MA39804
Authority / Receiving Office: MA · MA
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2014-03-27
Filing Date: 2015-03-26
Publication Date: 2017-02-01

Application Information

Patent Timeline

27 Mar 2014

Priority

26 Mar 2015

Application

MA39804

01 Feb 2017

Publication

MA39804A

IPC: A61K38/00; A61K39/00; C07K16/00; C12P21/08; C12Q1/68

CPC: C07K16/2842; A61K2039/505; C07K2317/24; C12Q2600/106; C12Q2600/158; C12Q1/6883; A61P1/04; A61K39/395

Inventors: HACKNEY Jason A.; KEIR Mary

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Abstract

Biomarkers predictive of responsiveness to integrin beta7 antagonists, including anti-beta7 integrin subunit antibodies, and methods of using such biomarkers are provided. In addition, methods of treating gastrointestinal inflammatory disorders such as inflammatory bowel diseases including ulcerative colitis and crohn's disease are provided. Also provided are methods of using such predictive biomarkers for the treatment of inflammatory bowel diseases including ulcerative colitis and crohn's disease.

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