Manufacture and use of modern ovotransferrin (otf-m)

Abstract

This invention refers to the method of manufacture and purification of specific ovotransferrin also called modern ovotransferrin (otf-m) from the egg white, consisting of preparation of antigens, immunization of laying chickens with a certain antigen, purification and assessment of egg white-extracted otf-m. The specific ovotransferrin is extracted by a two-stage precipitation with various concentrations of ammonium sulfate and citric acid, followed by dialysis and freeze-drying. This invention also refers to the composition of antigens prepared from a mixture of antibiotic-resistant strains from a single species of bacteria or of an antigen prepared from a mixture of various antibiotic-resistant species of strains, isolated from patients in romania. This invention is susceptible for industrial use.