ARNI COMPOSITIONS AGAINST HEPATITIS B VIRUS (HBV) AND METHODS OF USE THESE

MA40851AUndetermined Publication Date: 2017-09-20ALNYLAM PHARMACEUTICALS INC

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Patent Information

Application Number: MA40851
Authority / Receiving Office: MA · MA
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2015-03-24
Filing Date: 2015-11-10
Publication Date: 2017-09-20

Application Information

Patent Timeline

24 Mar 2015

Priority

10 Nov 2015

Application

MA40851

20 Sep 2017

Publication

MA40851A

IPC: A61K31/713

CPC: C12N2310/14; C12N2310/315; C12N2310/321; C12N2310/322; C12N2310/335; C12N2310/3515; C12N15/1131; A61K31/713

Inventors: HINKLE Gregory; JADHAV Vasant

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Abstract

The present invention relates to arni agents, for example double-stranded arni agents, targeting the genome of the hepatitis b virus (hbv), and methods of using such arni agents to inhibit the expression of one or more hbv genes and methods of treating subjects with an HBV infection and / or an HBV-associated disorder, for example chronic hepatitis b infection.

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