IN VITRO CELL CULTURE METHODS FOR BETA-THALASSEMIA USING TYPE II ACTIVIN RECEPTOR LIGAND TRAPS
MA42160AUndetermined Publication Date: 2018-03-28CAPPELLINI MARIA +1
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Patent Information
- Application Number
- MA42160
- Authority / Receiving Office
- MA · MA
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2016-04-08
- Filing Date
- 2016-05-19
- Publication Date
- 2018-03-28
Abstract
The present invention relates to methods for treating beta-thalassemia in a subject comprising administering an actin II (actrii) receptor signaling inhibitor (e.g., an activin ligand trap) and using one or more in vitro cell culture methods: (i) selection of the subject to be treated according to the methods provided herein; and / or (ii) monitoring of the treated subject according to the methods provided herein.
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