New Composite Biofilms Based on Hydroxyapatite and Cellulose for Biomedical and Environmental Applications

Abstract

The present invention relates to composite biofilms composed of hydroxyapatite (HAp) and cellulose, both derived from natural resources, including Moroccan rock phosphate and natural cotton. These biofilms exhibit remarkable antibacterial properties, high biocompatibility, as well as optimized mechanical strength and flexibility. The invention provides biofilms with variable proportions of HAp and cellulose (1:1, 1:2, 2:1), adjusted according to the specific needs of the applications. These biofilms are particularly suitable for biomedical applications, such as medical implant coatings and wound dressings, thanks to their ability to inhibit bacterial growth and promote bone regeneration. They are also effective for the treatment of industrial wastewater, thanks to their ability to adsorb heavy metals and organic pollutants with an adsorption rate of up to 95%. Another key advantage of these biofilms is their ability to be reused over multiple adsorption / desorption cycles without significant performance loss, while maintaining high adsorption efficiency. The invention thus offers a sustainable and versatile solution, suitable for the biomedical and environmental industries, particularly for water purification and hospital infection management.