Method for diagnosing the activity of the non-infectious ocular inflammatory process in juvenile idiopathic arthritis in children

Abstract

The invention relates to medicine, in particular to rheumatology and ophthalmology and can be used for early diagnosis of the activity of the non-infectious ocular inflammatory process in juvenile idiopathic arthritis by determining inflammatory biomarkers in the lacrimal fluid in children, for establishing an effective treatment depending on the activity of the ocular inflammatory process.Summary of the invention consists in collecting lacrimal fluid from both eyes using Schirmer strips, then using the enzyme-linked immunosorbent assay, the concentration of the ocular inflammatory biomarker protein S100A12 is determined, if the value is determined to be ≤ 23.6 ng / mL, an inactive form of the ocular inflammatory process is diagnosed, if the value is determined to be 23.7…28.4 ng / mL, a mild activity is diagnosed, if the value is determined to be 28.5…106.34 ng / mL, a moderate activity is diagnosed, and if the value is determined to be > 106.35 ng / mL, high activity of the non-infectious ocular inflammatory process in juvenile idiopathic arthritis in children is diagnosed.