ABCB5-targeted stem cell reprogramming and Anti-aging strategies
MX2026004875APending Publication Date: 2026-10-02CHILDRENS MEDICAL CENT CORP +1
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Patent Information
- Application Number
- MX2026004875
- Authority / Receiving Office
- MX · MX
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-10-23
- Filing Date
- 2026-04-22
- Publication Date
- 2026-10-02
Abstract
Methods and compositions for rejuvenating and reprogramming stem cells are disclosed. The methods involve administering to a subject an ABCB5 targeted composition comprising an anti-ABCB5 antibody conjugated to a therapeutic payload comprised of an epigenetic reprogramming factor or a nucleic acid encoding an epigenetic reprogramming factor in an effective amount to reprogram and rejuvenate ABCB5+ stem cells in the subject. The compositions include anti-ABCB5 antibody conjugated to a therapeutic payload comprising an epigenetic reprogramming factor or a nucleic acid encoding an epigenetic reprogramming factor.
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