BIFUNCTIONAL DEGRADERS OF IgG4 IMMUNOGLOBULINS

MX2026009065APending Publication Date: 2026-10-02BIOHAVEN THERAPEUTICS LTD
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Patent Information

Application Number
MX2026009065
Authority / Receiving Office
MX · MX
Patent Type
Applications
Current Assignee / Owner
Priority Date
2025-01-26
Filing Date
2026-07-22
Publication Date
2026-10-02
Patent Text Reader

Abstract

A composition of matter including an IgG4-binding moiety, a cellular receptor-binding moiety which binds to hepatocytes or other degrading cells through asialoglycoprotein receptors (ASGPR) on the surface of hepatocytes or other degrading cells in a patient or subject, and optionally, a linker moiety connecting the IgG4-binding moiety and the cellular receptor-binding moiety, wherein the composition of matter is useful for removing IgG4 from a subject or patient.
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