METHOD OF DUAL-ACTIVITY INSECTICIDE COMPOSITIONS.

Abstract

An insecticidal composition containing two active ingredients, transfluthrin and imiprothrin, is described. The insecticidal composition may also contain at least one solvent and one propellant. The weight percentage of each active ingredient may be approximately 0.01% to 0.5% by weight.

Description

METHOD OF DUAL-ACTIVITY INSECTICIDAL COMPOSITIONS CROSS-REFERENCE TO RELATED APPLICATIONS The present application received priority over U.S. Application No. 16 / 442,818, filed on the 17th of 2QÍ9< the contents of which are incorporated herein for reference in your interest, REFERENCE TO RESEARCH OR DEVELOPMENT SPONSORED BY THE FEDERAL GOVERNMENT Not applicable. SEQUENCE LIST Not applicable, BACKGROUND OF THE INVENTION The present description relates to an insecticidal composition and, more particularly, to an insecticidal aerosol composition, comprising at least two active ingredients and effectively knocking down and killing both flying and crawling insects. Insecticides have been used for years to prevent insects from attacking humans, animals, and crops. Insect-borne diseases are a significant health hazard. Insects (mosquitoes, flies, and similar insects) transmit a range of diseases caused by the victim's exposure to infectious agents such as viruses (Chikungunya, yellow fever, dengue, etc.), bacteria (Lyme disease, plague, etc.), and parasites (malaria, sleeping sickness, leishmaniasis, phylaniosis, etc.) carried by the insect. For example, flying insects, such as mosquitoes, cause more human suffering than any other organism: more than a million people die annually worldwide from mosquito-borne diseases. Mosquitoes not only carry diseases that affect humans, but they also transmit various diseases and parasites that affect other animals, such as dogs and horses. These include canine heartworm, West Nile virus (WNV), and Eastern equine encephalitis (EEE). In addition, mosquito bites can cause severe skin irritation as a result of an allergic reaction to the mosquito's saliva, leading to inflammation and itching at the affected site, and can result in the introduction of other disease-causing agents. Crawling insects, such as ants and cockroaches, are also responsible for health problems. Cockroaches in the home are a health hazard not only because of the risks that cockroach antigens pose to asthmatics, but also because they can carry disease-causing agents. Cockroaches can carry intestinal diseases such as diarrhea, dysentery, typhoid fever, and cholera. The active ingredients of insecticides (AI) are usually classified into three types: immediate neutralization (KD) (i.e., instant action, but the insect can recover); Residual killing activity (e.g., continues killing for some time after application), and synergies that support or help provide residual killing activity (e.g., piperonyl butoxide (PBO₄)). Known residual killing agents include Praliethrin (ETOC), d-tetramethrin (Neo Pynamirt Forte), Propoxybenzone Bendiocarb, Imiprothrin, Transfluthrin, and Methfluthrin. Known residual insecticides include d-phenothrin (Sumilrin), cypermethrin, cyphlenein, and deltamethrin. Commercially available insecticides may also include synergists, which are used to provide a degree of residual activity to an insecticidal compound. Some examples of synergists include, among others, α RBO and pyrodone (MGK-2B4). What is needed in the industry is an insecticidal composition that can provide speed of neutralization and mortality without the use of a known killing agent. Therefore, it is desirable to have an insecticidal composition capable of quickly and efficiently knocking down and killing both flying and crawling insects in a single product without the need for synergistic additives. It is also desirable to reduce the number of active ingredients (As) present in the insecticide. BRIEF DESCRIPTION OF THE INVENTION The modalities of the present description describe an insecticidal composition comprising transfluthrin and imiprothrin. Both transfluthrin and imiprothrin are considered neutralizing agents, and each individually provides little or no insect mortality. In the present disclosure, the applicant demonstrates that a combination of these two immediate neutralizing agents unexpectedly provides both immediate neutralization and long-lasting mortality. In certain embodiments, transfluin is present in a proportion of between 0.05% and 0.5% by weight and imiprathrin in a proportion of between 0.01% and 0.5% by weight. In certain embodiments, transfluin is present in a proportion of between 0.08% and 0.1% by weight and imiprathrin is present in a proportion of between 0.03% and 0.05% by weight. The insecticidal composition may be a water-based formulation or a hydrocarbon solvent (HC)-based formulation. The water-based formulation may also comprise a hydrocarbon solvent component. One embodiment of the present description is an insect-killing composition 25 comprising transfluthrin, imiprothrin, and solvent. The composition comprises from approximately 0.05% to approximately 0.5% by weight of transfluthrin and from 0.01% to 0.5% by weight of imiprothrin. Certain embodiments comprise from approximately 0.08% to approximately 0.1% by weight of transfluthrin, and from approximately 0.03% to approximately 0.5% by weight of imiprothrin. In one embodiment, the solvent comprises approximately 50% to approximately 75% by weight of water. In one embodiment, the composition comprises approximately 7% to approximately 11% by weight of hydrocarbon solvent, selected from the group consisting of cyclic hydrocarbons (Cg-Cv), acyclic hydrocarbons (Cg-Cm), naphtha, petroleum distillate, paraffins, isopampins, isoparaffins, isoparaffins, phosphates, isoparaffins, phosphates, isoparaffins, cyclases, and any combination thereof. In one embodiment, the composition comprises one or more emulators. In one embodiment, the composition comprises approximately 0.1% to approximately 2.0% by weight of emulators. In one form, the solvent comprises approximately 25% to 1S approximately 55% by weight of hydrocarbon solvent, selected from the group consisting of Cs-Ct isolating hydrocarbons, Cy-C® aucyclic hydrocarbons, naphtha, petroleum distillate, paraffins, isoparaffins, isoparaffinic hydrocarbons, cycloparaffins, alkanes, isoalkanes, cycloalkanes and any combination thereof. In one embodiment, the solvent is substantially anhydride. In one embodiment, the composition comprises a polar organic solvent. In one embodiment, the composition comprises a polar organic solvent in approximately 0.5% to approximately 5.0% by weight. In one embodiment, the polar organic solvent is an alcohol. In one embodiment, the composition comprises a propellant, selected from the group consisting of methane, ethane, propane, methane, isobutane, n-butene, and isobutane. dimethyl ether, 1J-difluoroethane, 1,1,1,2,4-ethanol, carbon dioxide, nitrogen, air, and any combination thereof. In one embodiment, the propellant is present in approximately 10.75 to approximately 80% by weight. In one embodiment, the composition given in the formula is such that the composition is discharged in its foam form. One embodiment of the present description is an insect-killing composition comprising transfluthrin, imiprothrin, solvent, and propellant. In one embodiment, the transfluthrin is approximately 0.05% to approximately 0.5% by weight and the imiprothrin is approximately 0.01% to approximately 0.5% by weight. In another embodiment, the composition comprises approximately 0.08% to approximately 1.1% by weight of transfluthrin, and approximately 0.03% to approximately 0.05% by weight of imiprothrin. In yet another embodiment, the propellant is approximately 10% to approximately 80% by weight, selected from the group consisting of methane, ethanol, propane, isobutane, N-ethanol, isobutane, dimethyl ether, 1,1-difluoroethane, 1,1,1,2-tetrafluoroethane, carbon dioxide, nitrogen, air, and any combination thereof. In one modality, the composition of the formula is such that the composition is discharged in the form <fe espuma. In one embodiment, the solvent comprises approximately 50% to approximately 75% by weight of water. In another embodiment, the composition comprises approximately 7% to approximately 11% by weight of hydrocarbon solvent, selected from the group consisting of Cs-Cm alicalcic hydrocarbons, C₆C₆ hydrocarbons, naphtha, petroleum distillate, paraffins, isopamffins, isoparaffinic hydrocarbons, chloroparaffins, alkanes, isoalkanes, chloroalkanes, and any combination thereof. In one embodiment, the solvent comprises approximately 25% to approximately 55% by weight of hydrocarbon solvent, selected from the group consisting of silicate hydrocarbons Ct-.-C'· and alkaline hydrocarbons Cv-Cm naphtha. petroleum distillate, paraffins, isoparaffins, isoparaffinic hydrocarbons, chloroparaffins, alkanes, isoparaffins, chloroparaffins and any combination thereof. In one embodiment, the solvent is substantially anhydride. In one embodiment, the composition comprises a silvery polar tobent. In a fifth embodiment, the polar organic sobent is alcohol. In one embodiment, the present deserippet is an insect-killing composition comprising transfitrine, imiprothrin, solvent, propellant, and a polar organic solvent. In one embodiment, the composition comprises between approximately 0.05% and approximately 0.5¾ by weight of transfitrine, between approximately 0.01% and approximately 0.5% by weight of imiprothrin, between approximately 25% and approximately 85% by weight of a solvent, and between approximately 10% and approximately 80% by weight of a propellant. Certain embodiments comprise a method for killing insects, the method comprising providing an insecticidal composition as described herein in 15 a dispenser, which dispenses the composition at a rate of between approximately 1.5 grams / second and approximately 3.5 grams / second, and instructing a user to spray the composition for a duration of typically 8 to 12 seconds to fog a room for flying insects, and less than about 5 seconds to spray directly at crawling insects. DETAILED DESCRIPTION OF THE INVENTION This paper describes an insecticidal composition designed to knock down and kill both flying and crawling insects more effectively than other known compositions. In the field of pest control, it is known that households tend to suffer from both flying and crawling insects. Therefore, it is important to develop an insecticidal composition that can knock down and kill both flying and crawling insects in a timely manner. An insecticidal composition comprising two active ingredients known primarily for their rapid neutralization, but not their death, has been found to provide such a benefit. The insecticidal composition according to an embodiment of the present disclosure is an AI package that can be used in a water-based formulation or in an HC solvent-based formulation. The two AIs used in this AI package, fransfluthrin and imiprothrin, are considered good KD actives. However, unexpectedly, the applicants were able to achieve a combination of good neutralization and long-lasting mortality without the use of a synergist or a separate AI known to provide long-lasting mortality / killing benefits. The insecticidal composition, according to a report, provides reduced exposure to the insecticide in the application. The insecticidal composition results in a beneficial minimalist approach to achieving both KD and mortality along with a relatively low amount of insecticide. Other compositions. Commercially available insecticides typically require three active ingredients (AIs) or three AIs and one synergist to achieve this level of efficacy. Therefore, the insecticide formulation described herein requires fewer AI components and synergists, resulting in increased convenience for the user. In certain formulations, the insecticidal composition includes transflurin and imiprothrin. Transflurin is a fast-acting and persistent pyrethroid insecticide. It has the molecular formula C₂C₂F₄O₂. Imiprothrin is another pyrethroid insecticide, which has the molecular formula C₂H₁₂N₇O₄. To determine the concentration of each of the IAs, the type of IAs, the spray rate of the composition, and the instructions for use are taken into account. In some modalities, the spray rate of the IAs is in the range of approximately 1.0 grams per second to approximately 2.0 grams per second. In other modalities, the spray rate of the IAs is in the range of approximately 2.0 grams per second to approximately 3.0 grams per second. In five other modalities, the spray rate of the IAs is in the range of approximately 3.0 grams per second to approximately 5 grams per second. In some modalities, the spray rate of the IAs is in the range of approximately 1.5 grams per second to approximately 3.5 grams per second. Instructions for use of aerosol compositions may indicate to the user to spray for about 4 to about 12 seconds to fog a room in search of night owls.In other models, users are instructed to spray for approximately 7 to 10 seconds. In some models, the instructions for use may instruct the user to spray for less than approximately 2 seconds for a direct spray on a crawling insect. In some models, the instructions for use do not specify a time period for misting a room in the case of flying insects, nor the duration of a direct spray on a crawling insect. It is desirable to provide an insecticidal composition comprising a particular amount of active ingredient (AI) that achieves its best efficacy (ability to kill or knock down pests) when used at a specific spray rate and for a specific amount of time (duration of the spray). In certain embodiments, transfluthrin is approximately 0.05% to approximately 0.5% by weight and imiprotin is approximately 0.01% to approximately 0.5% by weight. In certain embodiments, the... Transfluthrin is approximately 0.08M to approximately 0.1% by weight, and imiprothrin is approximately 0.03% to approximately 0.053¾ by weight. According to one exemplary formulation, transfluthrin is approximately 1% by weight, and imiprothrin is approximately 0.03% to approximately 0.05% by weight. In some formulations, the weight percentage of each component may vary, and the weight percentage of each component may be at least approximately 0.01%, or less than or equal to approximately 0.1%, or greater than or equal to approximately 0.03%. While specific values ​​are mentioned for the present formulation, it should be understood that, within the scope of the description, the concentrations of all ingredients may vary to suit different applications.The concentration ranges of the IAs are associated not only with the type of IA, but also with the spray rate and the instructions for use, including, but not limited to, the duration of the spray and / or the recommended proximity to the pest. The insecticidal compositions of the present invention may be in a water-based composition or in an HC solvent-based composition. In certain embodiments, the insecticidal composition is a water-based composition, including transfluthrin, imiprotocin, and water. In certain embodiments, the water is present at approximately 0% to approximately 90% by weight, preferably from approximately 40% to approximately 85% by weight. In one preferred embodiment, the water is present at approximately 50% to approximately 75% by weight. In certain embodiments, the water-based composition further includes a hydrocarbon solvent. In certain embodiments, the hydrocarbon solvent in the water-based composition is a 0.20% hydrocarbon solvent in water. In certain embodiments, the 0.20% hydrocarbon solvent is present in a water-based composition at approximately 1% to approximately 20% by weight. In certain embodiments, the hydrocarbon solvent is present in a water-based composition at approximately 5% to approximately 15% by weight.In certain embodiments, the hydrocarbon solvent is present in a water-based composition at approximately 7% to approximately 11% by weight. In a preferred embodiment, the hydrocarbon solvent is present at approximately 8% to approximately 0% by weight. In certain embodiments of the insecticide composition, the water-based composition also includes a polar organic solvent. In certain embodiments, the polar organic solvent is present at approximately 0.5% to approximately 5% by weight. In a preferred embodiment, the polar organic solvent is present at approximately 1% to approximately 2% by weight. The polar organic solvent may be an alcohol-based solvent. The alcohol-based solvent may include, but is not limited to, methanol, ethanol, isopropanol, propanol, butanol, and similar substances.In addition, solvents such as, but not limited to, cottons, glycols, glycol esters and esters, for example, isopropyl ester and similar solvents, may be used. In certain embodiments of the insecticidal composition, the water-based composition also includes one or more emulators present up to approximately 2.0% by weight. In some embodiments, the one or more emulators are present at approximately 0.1% to approximately 2.0% by weight. In a preferred embodiment, the one or more emulators are present at approximately 0.5% to approximately 1.0% by weight. The emulators may include, but are not limited to, sodium stearates, mono- and diglycerides, and tectene. lanolin alcohols, cetearyl alcohol, polysorbates, laurato ele sorhitsn, amphoteric and anionic surfactants and non-ionic alkyl polyglucosides.In certain forms of the insecticidal composition, the water-based composition further comprises one or more corrosion inhibitors or corrosion inhibition systems. In certain embodiments, the insecticidal composition is a substantially anhydrous hydrocarbon solvent-based composition that includes transfilterin, imiprothrin, or hydrocarbons as the primary solvent. In certain embodiments, the hydrocarbon solvent is present at approximately 10% to approximately 90% by weight. In certain embodiments, the hydrocarbon solvent is present at approximately 20% to approximately 75% by weight. In a preferred embodiment, the hydrocarbon solvent is present at approximately 25% to approximately 55% by weight. In certain embodiments of the insecticidal composition, the hydrocarbon solvent-based composition also includes an organic polar solvent. In certain embodiments, the organic polar solvent is present at approximately 0.5% to approximately 5% by weight. In a preferred embodiment, the organic polar solvent is present at approximately 1% to approximately 2% by weight. The organic potash solvent can be an alcohol-based solvent.The alcohol-based solvent may include, but is not limited to, methanol, ethanol, isopropanol, propane, butane, and the like. Additionally, solvents such as, but not limited to, cotton, glycols, glycols, and phosphates, for example, isopropanol, and the like. In certain formulations of the insecticide, the hydrocarbon solvent-based composition also includes one or more additives. These additives may include, among others, sorbitan stearates, glyceryl monothiates, lecithin, lanolin alcohols, cetearyl alcohol, and phosphorbates. Sorbitan laurate, sorbitan monooleate, sorbitan monostearate, sorbitan monopalmitate, amphoteric and ammonium surfactants, and nonionic alkyl polyglycosides. In certain embodiments of the insecticidal composition, the hydrocarbon-based composition further comprises one or more corrosion inhibitors, or a corrosion inhibition system. While specific solvent values ​​are selected for these formulations, it should be understood that, within the scope of this description, this value may vary widely to suit different applications. For example, the solvent weight percentage may increase to dissolve more 1As when, for instance, there are additional 1As in one formulation compared to another. The solvent weight percentage is balanced to effectively dissolve the 1As and effectively penetrate the insect cuticles. In certain embodiments, the solvent may be aliferic hydrocarbons (Cs-Cj), alkaline hydrocarbons (Cs-Cm), naphtha, petroleum distillate, paraffins, isoparaffins, isoparatinteps hydrocarbons, cycloparaffins, alkanes, isoparatinteps, cycloparaffins, alkyls, isoparatinteps, cidotenes, and the like, and any combination thereof. In certain embodiments, the solvent is a petroleum distillate. In certain embodiments, the petroleum distillate is composed of hydrocarbons, Ou-D <?, malcanos, ísoalcanos, cíclicos. <2% do aromáticos. En ciertas modalidades, ei solvente es un hidrocarburo isoparafínteo. En ciertas modalidades:, el hidrocarburo isoparafínico es la nafta (petróleo), pesada tratada con hidrógeno. En ciertas 10 modalidades, el solvente está compuesto de un destilado de petróleo o un hidrocarburo isoparafínico 0 ambas. Ciertas modalidades pueden comprender por lo menos dos solventes.In certain embodiments, the molar ratio of at least two solvents may be in the range of approximately 1 to approximately 1:100 or approximately 100:1 to approximately 1:1 based on the total concentration of the solvents. In certain embodiments, the solvent is present in an appropriate amount to dissolve the IAS, and may also contribute to the carrier efficacy, which is defined as the degree to which a solvent induces the penetration of an insecticide into the pest. Petroleum distillates are commonly used to refer to alphic hydrocarbons, defined to include both natural and synthetic carbonic hydrocarbons. Petroleum distillates may include mineral spirits, kerosene, spirits, naphtha, Staddard solvents, and the like. These products may contain traces of benzene and / or other aromatics. Despite the non-limiting examples of solvents offered in this document, other solvents, such as acetone, butylglycerol, carbon chloride, chloroform, chloropantanol, 25 cresol, cyclohexanol, cyclohexane, dichloromethane, 11-dichlorobenzene, 1,1-dichloroethylene, 1,2-dichloroethylene, dichloroethylene, 1,2-dichloropropane, dibenzene, dimethyl carbonate, N-methylformene, 1,4-ethylhexane, ethylbenzene, formaldehyde, furfuryl alcohol, isophorone, isopropane, and kerosene., mesityl oxide, mesityl, methanol, 2-methoxypropanol, methoxymethylcellulose, methoxychlorohexanone, 5-methylchlorohexanone, methylchloroisobutylcarbinol, N-methylchloroisobutylcarbinol, methylchloroisobutylcarbinol, acetic acid, myrobenzene, 1-methylchloroisopropylene, methylpropane, petrolatum, pentachloroethane, phenol, propylbenzene, propyl bromide, propyl chloride, pyridine, styrene, tetrabenzylphenol, 1,1,2-tetrachloroethane, tetrachloroethylene, tetramethylchloroisopropylene, tetramethylchloroisopropylene, tetrachloroisopropylene, tetramethylchloroisopropylene, tetrachloroisopropylene, toluene, 1,1,1-trichloroethylene, 1,1- 10 Hchloroethane, 1-chloroethylene, trimethylbenzene, vinyltoluene, xythene, and the like, or any combination thereof, may also be used as a solvent. In certain embodiments, the insecticidal composition further comprises a propellant. In other embodiments, the insecticidal composition may further comprise a fragrance. Such embodiments may comprise a fragrance of approximately 0.1% to approximately 0.2% by weight. According to certain embodiments of this disclosure, the insecticidal composition is an aerosol insecticidal composition suitable for industrial and domestic applications. One embodiment comprises a dispensing unit having aerosol dispensing means, at least two active ingredients (AIs), a solvent in a weight percentage sufficient to dissolve 20% of the AIs, and a propellant gas at a pressure sufficient to dispense the AIs dissolved in the solvent from the dispensing means as an aerosol. An aerosol insecticidal composition is ideal for use against both flying and crawling insects.For example, the aerosol composition can be sprayed into the air for any flying insect and can be used as a preventative measure. For crawling insects, the aerosol composition can be sprayed directly onto the insect. •14 The propellant binds to the aerosol container and influences how the insecticide composition is discharged. The composition can be discharged as a foam, stream, or spray. The pressure typically created by the propellant is approximately 2.4 to 9.7 bar (35 psi to 140 psi). If the propellant concentration is increased, the aerosol composition may be affected. By adjusting the propellant, surfactants, and solvent used, foams that break quickly can be produced, or foams that remain visually unchanged for days can be created. To produce an aerosol, the propellant must have sufficient dispersion energy to overcome the surface tension of the liquid mixture, in addition to the forces of cohesion and adhesion. To produce an aerosol product composition, vapor pressure, spray characteristics, solubility, flammability, and corrosion are taken into account. Aerosol propellants may comprise compressed gases, soluble gases, and liquefied gases. Many of these forms of aerosol propellants may be used in connection with this disclosure. In some embodiments, the propellant may be carbon dioxide, nitrogen, air, and the like, or any combination thereof. In some embodiments, the propellant belongs to the category of liquefied gases, including, but not limited to, hydrocarbon propellants. In some embodiments, the propellant may be methane, ethanol, pyrophosphate, isobutene, n-butane, isobutane, dimethyl ether, 1-difluoroethane, 1,1,1,2-ephrafluoroethane, and the like, and any combination of two or more of the same. In some embodiments, the propellant is propane. In other embodiments, the propellant is butane, including both n-butane and isobutene. Some embodiments may comprise at least a first propellant and a second propellant. In some embodiments, the first and second propellants are in a ratio ranging from approximately 1:1 to approximately 100:1, based on the total concentration of the first and second propellants. In certain embodiments, the first propellant is propane and the second propellant is butane, including both n-butane and 5-isobutane. Furthermore, in certain embodiments, the propellant is present in a proportion of approximately 0.5% to approximately 90% by weight, more preferably from approximately 10% to approximately 80% by weight. In one embodiment of the HC solvent-based composition, the propellant is present in a proportion of approximately 50% to approximately 70% by weight, more preferably from approximately 65% ​​to approximately 70% by weight. In one embodiment of the water-based composition, the propellant is present in a proportion of approximately 15% to approximately 40% by weight, more preferably from approximately 34% to approximately 38% by weight. In one embodiment, the composition of the formula is such that the composition is discharged as a foam. Although specific values ​​chosen for the prepotent are recited, it should be understood that, within the scope of disclosure, the value of this parameter can vary widely to suit different applications. According to EPA standards, a dead (or killed) insect must be an insect with no movement whatsoever, no jerking, no antennal movement, etc. A dead insect is probed or subjected to other stimuli to verify its lack of movement. An insect is considered "knocked down" when it is between death and full mobility; that is, knockdown is often measured as the insect's inability to respond to a stimulus such as light or touch. In the case of mosquitoes, knockdown is defined as the fact that mosquitoes rest on the floor of the The camera and experience some slow, erratic behavior, such as lying on their back or side, spinning erratically in place, or the inability to maintain normal flight for more than a few centimeters, giving the impression of hopping. Especially when the actual mortality rate may be difficult to assess, neutralization is used to measure the effect of a pesticide. It is desirable not only to knock down, but to kill the insects: to prevent the reproduction of insects resistant to neutralization. Elimination resistance (kdr) describes cases of resistance to diphenylethylane (e.g., ODT) and pyrethroid insecticides in insects and other arthropods that result from a reduced sensitivity of the nervous system caused by point mutations in the insect's genetic makeup. This mutative resistance is characterized by the presence of kdr alleles in the insect's genome.Resistance to elimination remains a threat to the continued usefulness of pyristroids in controlling many pest species. Therefore, it is desirable to have an insecticidal composition capable not only of knocking down these insects, but also of killing them. The currently disclosed insecticidal composition exhibits faster and higher neutralization rates and higher mortality rates against both flying and crawling insects compared to other tested compositions. Other compositions, including other compositions available on the market, may only have fast and high neutralization rates against flying or crawling insects, but not against both. Furthermore, the disclosed insecticidal composition also exhibits insect mortality and proven activity to kill both flying and crawling insects after application. Other known compositions require the addition of a residual active agent or a synergist to ensure insect mortality. The currently disclosed insecticidal composition provides rapid insect neutralization and mortality without the addition of a residual active agent or a synergist. Any of the modalities described in this document may be modified to include any of the structures, compositions, or methodologies disclosed in relation to different modalities. EXAMPLES Formulas A, B, C, and D (Examples 1 to 4) are water-based formulas and comprise about 0.1% transfluthrin; about 0.03% or 0.05% imiprothrin; about 69% to 70% water; about 19% propellant; about 8% to 9% C₆-C₅S branched alkanes; about 1% to 2% isopropyl alcohol; about 0.7% emulator; and about 0.46% corrosion inhibitor. Formulas F, G, and H (Example 5) are HC solvent-based formulations and comprise about 0.08% or 0.1% transhydrogen; about 0.03% imiprothrin; about 50% propellant; about 47% to about 49% n-alkanes / isoalpanes; and about 1% to about 2% isopropyl alcohol. Formula E is similar to formulas F, G, and M, except that formula E contains 0.03% propellant, 0.03% imiprothrin, and 0.1% cyparathrin, but does not contain transhydrogen. Formulas I and J are solvent-based HG formulations comprising 0.15% of esbiothrin, 0.04% of transflutaha and 0.11% of O^fehptnna (i); or 0.3% of p* tetramethrin, 0.1% of permethrin and 0.1% of D4anofhns (J). Example 1 The tests: with adult male German cockroaches (7 weeks since selection) consist of five replicates per sample. The preparation of the cockroaches. German cockroaches for testing were anesthetized with CQ2, sorted, and placed in greased Tn-State 1&-A plastic cups. Immediately before testing, the German cockroaches were transferred to clean, greased Lucite rings (5 cm high x 10 cm in diameter) with a stainless steel mesh (6 x 7.5 mm / cm²) attached to the bottom of the ring. The cockroaches were then allowed to recover from the anesthesia. GO2 was administered overnight. No food or water was provided during the recovery period. Following preparation and recovery, cockroach test containers were placed (one at a time) in the CSMA spray tower and exposed to a directed spray at a distance of 46 cm (18 in). After each spray, 10 cockroaches were immediately transferred to a clean, greased glass battery jar (15 cm high x 15 cm in diameter) for the selected observation period. A 15.0 cm diameter No. 2 filter paper was placed at the bottom of the glass jar for each replicate. At the end of the observation period, the insects were removed from the glass jars with CQ2 (if necessary) and placed in 240 ml plastic cylinders and kept for 24-hour mortality counts. Five additional replicates were performed as untreated contrasts.Each replicate was timed to 100% mortality to provide comparative data. Compositions B (with 0.1% transfluthrin and 0.05% imiprothrin) and C (with 0.4% transfluthrin and 0.03% imiprothrin) performed as well as, if not better than, the other compositions tested with transfluthrin and phenothrin, or that lacked the presence of piperine butoxide (PBO) in the delimitation percentage of Blatella germanica (German cockroach). 1 second of rock, 5 pounds te' o te. is te O & tei : te E ® a, oo Ό £ ín o Sí CL bogs X>X· O í^ Úí p O o Q •>s* te O te· *3 ste v.> Xví germánica) par ra x··* te' O fe q JS te te OOO o te> t' Φ ε >Í5 K5 O Vj : .•X · s'SX & Xi T>vc te> 'te has (Blateüa te; ?« te & 'S te C 1 £ te te te te' Φ $ Tabla 1 Prueba da neutrai&acíán de cucaraci tetones, 10 msectos / repstieión .N g E δ s >>* & O te: te X.' j δ> “Γ-- te <te δ' r« J 1 Φ íte C': te 'te· O te O <>OO The media within i / -Kmméc te 0 Φ te¨ ΙΟ id Example 2 The tests with houseflies (Wsea) consisted of five replicates per sample. Preparation for the tests involved anesthetizing the flies with CO2, sorting them, and placing them in clean, sealant-free containers. The flies were left to recover from the CO2 overnight. During the recovery period, they were provided with sugar water. After preparation and recovery, the test containers of flies (one at a time) were placed in the QSMA aerosol tower and exposed to a targeted spray. After each spray, neutralization counts were taken for the selected observation period. The results are not significantly different between Compositions B and C of this disclosure compared to the other tested compositions comprising Praltetrine and d-Phenotrioa, or requiring the presence of piperothyl butoxide (P8O / Exposure to Compositions B and C results in an average neutralization percentage, in 10 seconds of 90% and 74%, respectively, in the housefly (Musca domestica). Table 2. Test of neutralization of the housefly (Musca domestica) by direct spray! 1 second of spray, 5 repetitions, 10 insects / repeat T fatsmíema Dosts 3 '*5 ” nvj:\-1 , _ SrgmS'-kv | o© rw<? 40 50 eo Compuesto A i i [ 0.1% Fraterna ;3.31g ; T& MW 100a toga 100a 100a > ub '' Ό > w ; i 1 ................................................. .................L..................1............L . .. ,v Compuesto B ; · ;O;1%Trans0tóna ; 3.28g HQOa lüito iDua Ws Wto 0 IfUipfWina iil· í ? r Compuesto C; ii TmnstWna HOÜa Wüa IWa WCfe Wa j í ' O;GS% imípmtrina ΐ ii : Compuesto D i ; i 0.1¾ Transfkárím l 1 2 31q ?8a lÜDa 100a 00 a TOOa 0 03% ¡nvprotnna ; ; 0.4% P8C f | 'Las medias.dentro de ¡as-columnas con la síma carta no son sígnücatívamánte differentes; (Ρ^Ο,Οδ) All Tukey-Kramer pairs. Example 3 The tests with midges consist of three replicates per sample. Preparation for the test consists of aspirating the midges from the test cage with a tubular aspirator and placing them in clean 240 ml (0.5 pt) cardboard cylinders with a tight-fitting aluminum mesh (6 x 7 mt / cm²) inserted at the top. After preparation; Mosquitoes are released into the test chamber through one of the portholes located in the chamber. After a 1-minute acclimation period, the mosquitoes are exposed to a targeted discharge. After each discharge, neutralization counts are repeated at 2-minute intervals for 12 minutes after the initial exposure. At 2 minutes, compositions B (comprising 0.1% transfluthrin and 0.05% imiprothrin) and C (comprising 0.1% transfluthrin and 0.03% imiprothrin) have a faster and higher neutralization rate of the southern house mosquito (Cuex quinquefasciatus) than any of the other compositions tested. With regard to the anticipated KT5Q and KT9G neutralization times: compositions B (comprising 0.1% Transfluthrin and 0.05% Imiprothrin) and C (comprising 0.1% Transfluthrin or 0.05% Imiprothrin).03%) perform equally well, if not better, than the other tested compositions comprising Praltetrin and d-Phenothrin, or requiring the presence of ρΐρ^ηϊΙ,ϡ butoxide (PBO) in the percentage of neutralization of the domestic mosquito dei sur. Table 3 Mosquito neutralization test (Culex quinquéfasciatus) in free flight Oasis of equal weight: 0.65 Gram. ; Tmtoiwip • Average of! % of nebí miración _ 6 _ϊνΙΐΠΜίΟδ BW 12 Composite A 0 1 % Pratotáns 0 125% d-Fenomna 10a 43a SSa 77 a 84a w ',' <UÍkX Compuesta 8 0 1% Is^^irst 0.05% Imipmthna 23a 443 64a í 8ba $*2a Con puesto C 0 1% Ttonslhtomu 0 03% Iwrwim 27a 43a Z tcí 83a 94a Compuesto D 0 l%TtonsfMmp 0 03% impmPma 0.4% PBO 13a 3óa §3a 76a 64a 98a Table 3a PW-Grady test with GuW gídnqtíafesa&íüs (0.65 gram dose, 3 replicates). KTSO and KT90 values ​​predicted in minutes based on the inverse prediction of the Gomperte 3P fitting curve (alpha 0.05). 5 pratanwte % of Réu&al^c^n 'ispead curto ÍK<; Predicted time (mte) % ·% vmr tournament? L\h~:on predicates specified (KT)Híhte) í : t mp fair 5 or 1 be Pratetena 0 125% d-Fenotfóa ¿te 45®b tea MA j Cnmnneste 8 1 0 : G1% TsanstMnna : G 05% ímtproteina 5Í3 4£tei> G0 11:7a i Compound C 0 1% TumslBuna 0 Ocie Impromna 50 4. la 90 Compound D 0 1%Tmnsítetem Imtemteha 5G 5 2-m 90 sandpaper Comparison of the curve fitting model performed with Gompeuz 3P that propefdbns the best fit. The predicate values ​​for the formulas at a specified % value of nsutrafeac^ with overlapping confidence limits are not considered significantly different. Example 4 For efficacy tests in a Paet-Grady chamber, the aerosol was sprayed through the top port along the side wall of the chamber containing insects (Ctax pipius Ades albicpicius, Musca domestica). While testing the aerosol against mosquitoes, neutralization counts were recorded at 2, 4, 6, 8, and 10 minutes, and then the neutralized mosquitoes and the remaining mosquitoes were collected after 10 minutes to check mortality over 24 hours and the total number of mosquitoes was determined. In aerosol tests against houseflies, neutralization counts were recorded at time intervals of 3, 5, 10, and 15 minutes, then the neutralized houseflies and the remaining houseflies were collected after 15 minutes to check mortality over 24 hours and the total number of houseflies was determined. For the directed spray neutralization tests, the spray distance was 46 cm (18 in) and the directed discharge was approximately 1.0 second. German cockroach (Blattolta germanica) neutralization counts were recorded at time intervals of 15s, 30s, 45s, 60s, 75s, 90s, 105s, 120s, 136s, and 150s; American cockroach (Pennsiana americana) neutralization counts were recorded at time intervals of 15s, 30s, 45s, 80s, 75s, 90s, 155s, 120s, 180s, and 240s. and 30Qs, housefly (Musca domestica) neutralization counts were recorded at time intervals of 10, 20, 30, 40, 5, and 60 s, or until 100% neutralization was reached. At the end of the observation period, cockroaches (E. germanica, Periplaneta americana) and houseflies (Musca domestica) were removed to check for 24-hour mortality. Table 4a illustrates that composition G (transnuthrin at 0.1% and imiprothrin at 0.03%) demonstrates a neutralization percentage of the common or domestic northern mosquito (Cufex p / p&ns paff&ns) at 2 minutes at least twice that of the other compositions tested, except for the composition containing the combination of 25 esbiothrin and D-pheothrin. For the Asian tiger mosquito or the forest mosquito (A&des), the elimination percentage is comparable, if not better, than that of the other tested compositions. For the housefly (Musca domestica), as shown in Table 4b, the elimination percentage is comparable, if not better, than that of the other tested compositions, except those containing 0.3% D-astramethrin, 0.1% permetmine, and 0.1% D-phenothrin. The 24-hour mortality percentage of composition G was comparable to that of the other tested compositions.This indicates that composition G not only demonstrates good neutralization activity, but also good mortality in the two AI packages containing AIs known primarily for their good KD activity. The tetellas 4ct4d and 4e> German cockroach (Slattellia germanica), American cockroach (Periplaneta americana), and housefly (Musca domestica), respectively, provide the results (% neutralization, % mortality at 24 hours, rolled dose) of the aerosol. As can be seen, composition G demonstrates comparable, if not better, performance in the % neutralization and % mortality measured at 24 hours. Composition G provides both neutralization and mortality at 24 hours (residual effect) without the need for a residual active ingredient or a synergist such as PBO. ¢3 g WHAT do you say? jo E j [ £ ¢03⁄4 j 1 ; r*7 »y <» <ά 0 «3 Ό «í 75 OE Ί0 βΓ' < T5 g ϕ re re a. re as I ^IU s O * s £ : » & i' ; & Q ¿K $$ c< f-hí _____j k>.· (53⁄4 Ai>. 4 U'S <?4 re·*’ 45 *y <0 : o o >t¿ ow? í c ;O '3 re N «a* g re C Φ 13 Where did you believe O *rs id á *? Έ «· \jr y- ! iii 1 .... c» <í> faith? M c% -i…… <£>' WHERE? rem-, <0 ¢2¾ X;X VS'· 'ty *5* ® king -Q « 2 king king «i king SF king & <j φ i t¿ — íC? 4 ---- <*>·& 0 « re 13 sprayed doses) of the spray against Culexpij ; . o ; 4 king O *5 •xi &> it¿> ia”A 4 55 E re king □ king £ a V s>- ;?X jo 1 US. 4 V %Λ <? i VCJ l o. | t . :¾ & re J2 á 4* ‘íí :2 « M .w· : O .<> ! ** < *> t CA 3 1 ~ b ΪΓ > ~ : Ss * i*» iu > ζΑ φ í£ or έ >v •x? V ds ·&' V? 'BORN Ú> S' t *» - £? 0^x5 «J > ω $> ​​£ ~ Where ΑζΎ . Um J q$ .¿a 7 . ξ ; “. Ο Yes 2 ' 8 S SxJ / 4 0 <5 rf 4 '^* ;'A gf o “5 king '25 or king 2 or JE S***s in CE Oh <s> Φ u> í¿ re re re O © E re o Έ3 d re O •are re sprayed) of the spray against Musca domestica in the PeetOrady chamber, oa' ¢5: O CS INDUSTRIAL APPLICATION Numerous modifications of the present invention will be evident to those skilled in the art from the foregoing description. Accordingly, this description should be interpreted as illustrative only and is presented for the purpose of enabling those skilled in the art to make and utilize the invention and to teach the best way of carrying it out. Exclusive rights to all modifications falling within the scope of the appended claims are reserved.< / s>

Claims

1. An insect-killing composition comprising: transflutnna; tmiprotnna; 5 solvent.

2. The composition according to claim 1 comprising: from approximately 0.05% to approximately 0.5% by weight of transitones; and from approximately 0.01% to approximately 0.5% by weight of imiprotnna. 10 3. The composition according to claim 2 comprising: from approximately to approximately 0.1% by weight of transUutnna; and from approximately 0.03% to approximately 0.05% by weight of imíprntriná.

4. The composition according to claim 1, wherein the solvent comprises approximately 50% to approximately 75% by weight of water.

5. The composition according to claim 4 comprising approximately 7% to approximately 11% by weight of hydrocarbon solvent, 6. The composition according to claim 5, wherein the hydrocarbon solvent is selected from a group consisting of aliphatic hydrocarbons, including: petroleum, paraffins, isoparaffins, isoparaffinic hydrocarbons, cycloparaffins, alkanes, isoalkanes, dialkanes and any combination thereof, 7. The composition according to claim 4 comprising a 25 emulator.

8. The composition according to claim 7 comprising approximately 0.1% to approximately 2.0% by weight of an emulator, 9. The composition according to claim 1, wherein the solvent comprises approximately 25% to approximately 55% by weight of hydrocarbon solvent.

10. The composition according to claim 9, wherein the hydrocarbon solvent is selected from a group consisting of aphthous hydrocarbons CrCm, aphthous hydrocarbons Cs-Cm, naphtha, petroleum distillate, paraffins, isoparaffins, isoparaffinic hydrocarbons, chloroparaffins, alkane, isoalkanes, 1Q oidoalkanes and any combination thereof.

11. The composition according to claim 9, wherein the solvent is substantially anhydride.

12. The composition according to claim 1 comprising an organic polar solvent. 15 13. The composition according to claim 12 comprising approximately 0.5% to approximately 5% by weight of organic polar solvent.

14. The composition according to claim 12, wherein the organic polar solvent is an alcohol.

15. The composition according to claim 1 comprising a propellant, 16. The composition according to claim 15, wherein the propellant is selected from the group consisting of methane, ethane, propane, ethanol, isobutene, n-butane, isobutane, dimethyl ether, 1-difluoroethane, 1,1,1,2-tetrafluoroethane, carbon dioxide, nitrogen, air, and any combination thereof. 25 17. The composition according to claim 15, wherein the pre-product is present in approximately 10% to approximately 80% of the weight <x 18. The composition according to claim 15, wherein the composition of the formula is such that the composition is discharged in the form of foam, 19. A composition for insecticide comprising trans-transuterine, imiprotrin, solvent, and propolis.

20. The composition according to claim 19 wherein; 10 transfluthrin is approximately 0.05% to approximately 0.5% by weight. 10 miprothrin is approximately 0.01% to approximately 0.5% by weight.

21. The composition according to claim 20 comprising: approximately 0.08% to approximately 0.1% by weight of transfluthrin; and approximately 0.03% to approximately 0.05% by weight of imiprothrin. 15 22. The composition according to claim 19, wherein the propaleme is approximately 10% to approximately 80% by weight.

23. the composition in accordance with directive 19, wherein the composition of the formula is such that the composition is discharged in the form of foam.

24. The composition according to claim 19, wherein the proppant is selected from the group consisting of methane, ethanol, propane, n-butane, isobutane, diethanol, 1 / 1-difluorosthenes, carbon dioxide, nitrogen, air, and any combination thereof.

25. The composition according to claim 11 wherein the solvent comprising approximately 50% to approximately 75% is water.

26. The composition according to claim 25 comprising approximately 7% to approximately 11% by weight of hydrocarbon solvent.

27. The composition according to claim 26, wherein the hydrocarbon salvage is selected from a group consisting of apathetic hydrocarbons Cs-Cv, alidic hydrocarbons C^Cr?, naphtha, petroleum distillate, paraffins, isoparaffins, isoparaffinic hydrocarbons, cycloparaffins, alkanes, isosalcenes, cetalanes and any combination thereof.

28. The composition according to claim 19, wherein the solvent comprises approximately 25% to approximately 55% by weight of hydrocarbon solvent.

29. The composition according to claim 28, wherein the hydrocarbon solvent is selected from a group consisting of Cs-Ci hydrocarbons, C₅C₆ hydrocarbons, naphtha, petroleum distillate, paraffins, isoparaffins, isoparaffins, cycloalkanes, alkanes, cycloalkanes, and any combination thereof.

30. The composition according to claim 28, wherein the solvent is a substantial anhydride.

31. The composition according to claim 19 comprising an organic polar solvent, 20 32. The composition according to claim 31, wherein the organic polar solvent is an alcohol.

33. An insect-killing composition comprising: transfluthrin; imiprothrin; solvent; propellant; and organic polar solvent.

34. An insect composition comprising: between approximately 0.05% and approximately 0.5% by weight of fransflurin; between approximately 0.01% and approximately 0.5% by weight of imiprothrin; between approximately 25% to approximately 85% by weight of a propellant; and between approximately 10% and approximately 80% by weight of a propellant.