DISINFECTANT COMPOSITION

Abstract

The invention relates to a disinfectant composition comprising at least 80% by weight of water and a cationic surfactant. The composition provides superior antimicrobial benefits while also offering excellent antiviral activity after topical application, even when formulated with little or no ethanol.

Description

DISINFECTANT COMPOSITION FIELD OF THE INVENTION The present invention relates to a disinfectant composition. More particularly, the invention relates to a disinfectant composition comprising at least 80% by weight of water and a cationic surfactant. When applied topically, the composition of the present invention unexpectedly provides superior antimicrobial benefits while simultaneously providing excellent antiviral activity. Such a composition results in a bacterial elimination rate of at least 2 and a viral inactivation rate of at least 2 in less than 3 minutes after topical application, even when formulated with little or no ethanol. The disinfectant composition of the present invention is particularly gentle on the skin. BACKGROUND OF THE INVENTION Consumer concern regarding microbial and viral contamination is typically high. This is because savvy consumers are aware of the negative impact such contaminants can have on their health. In fact, illnesses such as sinus, ear, and throat infections, as well as bronchitis, pneumonia, and whooping cough, are all linked to bacteria. Viruses, which are parasites, are commonly associated with the common cold, the flu, and certain types of pneumonia. Consumers generally recognize that washing their hands regularly and avoiding touching their faces are good practices for minimizing the risk of illness. During epidemics, such as the Ebola outbreak, and pandemics, such as those caused by influenza, cholera, and HIV / AIDS, consumers know that these serious infectious diseases are best overcome with regimens that include medical treatment, social distancing, wearing face masks, and extensive handwashing. Information provided by the Centers for Disease Control and Prevention suggests that the COVID-19 (coronavirus) pandemic is the direct result of a virus that is more efficient and severe than influenza and that spreads rapidly from person to person through respiratory droplets. During such a pandemic, consumers know that washing and sanitizing their hands regularly is in their best interest. Disinfectant products are commercially available and are typically supplied as gels containing at least 60% ethanol by weight. While these products are known to provide good antibacterial benefits after application, some consumers avoid using high-ethanol products because they can dry out the skin, weaken the epidermal barrier, and accelerate the aging process. There is growing interest in developing a disinfectant composition that provides excellent antimicrobial and antiviral benefits while being safe and gentle enough for unlimited use throughout the day. Given consumer demand, there is also growing interest in developing a disinfectant composition that provides soothing and moisturizing benefits when applied topically and is gentle enough for use on the face and even on the most delicate consumer, babies. This invention, therefore, is directed to a composition comprising at least 80% by weight of water and a cationic surfactant. The composition of the present invention, when applied topically, unexpectedly provides superior antimicrobial benefits. LQCQ iP / ZZΖ / E / YILI while simultaneously providing excellent antiviral activity. This composition results in a bacterial elimination rate of at least 2 and a viral inactivation rate of at least 2 in less than 3 minutes after topical application, even when formulated with little or no ethanol. The composition of the present invention is also suitable for disinfecting inanimate surfaces such as tables, kitchen counters, clothing, and the like. Additional information Efforts to manufacture compositions that provide antimicrobial benefits have been described. U.S. Patents Nos. 4,374,126 and 5,417,968 describe compositions that impart antimicrobial benefits. Other efforts to manufacture compositions that provide antimicrobial benefits have been described. World Application WO08061375A1 describes hand sanitizers containing a four-carbon alkyl alcohol and lactic acid. Other efforts to manufacture compositions that provide antimicrobial benefits have also been described. U.S. Patent No. 9,044,403 describes hand sanitizers containing peracetic acid. Other efforts to manufacture compositions that provide antimicrobial benefits have also been described. U.S. Patent Application No. 2013202484 describes hand sanitizers containing a chlorite solution. None of the additional information describes a disinfectant composition as claimed in the present invention. BRIEF DESCRIPTION OF THE INVENTION In one aspect, the present invention relates to a disinfectant precursor comprising: a) less than 15% water by weight; and (b) a cationic surfactant, wherein the disinfectant precursor is suitable to be diluted to produce a disinfectant composition comprising at least 80% by weight of water that is capable of producing a bacterial elimination record of at least 2 and a viral inactivation record of at least 2 in less than 3 minutes after topical application and further wherein the composition is substantially free of ethanol, and where the total surfactant in the composition is more than 4.5% by weight and the cationic surfactant in the composition includes a combination of both cetrimonium chloride and benzalkonium chloride, the benzalkonium chloride constitutes at least 16.5% by weight of the combination. In a second aspect, the present invention relates to a composition comprising: a) at least 80% water by weight; and b) a cationic surfactant wherein the composition is capable of producing a bacterial clearance record of at least 2 and a viral inactivation record of at least 2 in less than 3 minutes after topical application and further wherein the composition is substantially free of ethanol, and wherein the total surfactant in the composition is more than 4.5% by weight and the cationic surfactant in the composition includes a combination LQCQ ίΠ / ZZΖηZ / E / YΙΛΙ of both cetrimonium chloride and benzalkonium chloride, the benzalkonium chloride constitutes at least 16.5% by weight of the combination. In a third aspect, the invention is directed to a method for disinfecting a surface comprising the step of bringing the surface into contact with the composition of the second aspect of the invention. In a fourth aspect, the invention is directed to the use of the composition of the second aspect of the invention to disinfect a surface. In a fifth aspect, the invention is directed to the use of the composition of the second aspect of the invention to prevent adverse skin reactions (such as the development of acne) by applying the composition topically to the skin under personal protective equipment. All other aspects of the present invention will become more readily apparent from the following description and examples. “Skin,” as used herein, includes the skin of the arms (including forearms), face, feet, neck, chest, hands, legs, buttocks, and scalp (including hair). “Disinfectant,” as used herein, means a bacterial elimination record of at least 2 and a viral inactivation record of at least 2 (both achieved) in less than 3 minutes after topical application to a surface. “Disinfectant precursor” means a composition that is a concentrate and suitable for diluting (or hydrating) with water to produce a ready-to-use disinfectant composition. “Combination,” as used herein, means the total weight of cetrimonium chloride plus benzalkonium chloride. “Skin-beneficial agent” means an ingredient suitable for enhancing a skin characteristic.“Surface,” as used herein, includes the skin or the surface of an inanimate object such as a table, computer monitor, doorknob, toilet seat, shopping cart handle, or even an article of clothing. A surface also includes the fur of an animal, such as the fur of a dog or cat. As used herein, “surface” preferably means human skin, and in particular, the skin of the face and hands. The dimonium and trimonium compounds used herein are intended to include salts thereof, especially chlorides and bromides thereof. The cationic surfactant, as used herein, is intended to include polyquaternium materials, such as, for example, polyquaternium-6. In one embodiment of the invention, the disinfectant composition of the present invention is a household care composition, specifically a laundry spray composition suitable for spraying clothing and upholstery requiring disinfection.The household care composition can also be a disinfectant spray composition for the kitchen or bathroom. In a preferred embodiment, the composition of the present invention is a topical composition for application to the skin to disinfect it by significantly reducing the number of bacteria and viruses on the skin. The composition of the present invention may optionally comprise added skin-beneficial agents such as emollients, vitamins and / or derivatives thereof, resorcinols, retinoic acid precursors, colorants, moisturizers or humectants, fragrances, sunscreens, a mixture thereof, or the like. The skin-beneficial ingredients may be water- or oil-soluble. The disinfectant composition is therefore an aqueous composition with a pH of 3.0 to 8.2, and the composition is continuous water.Viscosity, as used herein, is measured with a Brookfield RV 6 spindle at 20 rpm for 30 seconds at 25°C unless otherwise specified. LQCQ iη / ZZΖΠZ / E / YILI indicates otherwise. Still in another embodiment, the composition of this invention is a non-therapeutic and non-medicinal composition (although it includes cosmetics in nature) that is a continuous water liquid having a viscosity of less than 30,000 mPas (30,000 cps). In the absence of an explicit indication to the contrary, all variations described herein include all variations included herein. As used herein, substantially free of media less than 10% by weight. The antimicrobial benefits mean at least a clearance record of 2 in less than 3 minutes, whereby the antimicrobial evaluation is measured by means of the ASTM-E2783-11 test method (reapproved in 2016) which establishes the procedure for measuring the antimicrobial activity of water-miscible compounds using a clearance-by-time procedure.Viral inactivation is determined by evaluating the impact of microbiocides against viruses as specified in ASTM-1052-20. The term "comprising" is intended to encompass the terms "essentially consisting of" and "consisting of." For the avoidance of doubt, and by way of illustration, a composition comprising water, cationic surfactant, and preservative is intended to include a composition consisting essentially of the same and a composition consisting of the same. Except in operational comparative examples, or where explicitly stated otherwise, all numbers in this description indicating quantities or proportions of materials or conditions and / or physical properties of materials and / or use are to be understood as modified by the word "approximately." DETAILED DESCRIPTION OF THE INVENTION Regarding the cationic surfactants suitable for use, their application is limited only to the extent that they can be used for topical application to human skin. Such cationic surfactants typically have an HLB (hydrophilic-lipophilic equilibrium) of 7.5 to 28, preferably 8 to 25, and most preferably 9 to 20, including all variations thereof. In one embodiment of the invention, the cationic surfactant used comprises linear or branched-chain alkyltrimonium compounds, alkanoltrimonium compounds, or a mixture thereof. Suitable alkanoltrimonium compounds include lauroylethyltrimonium methosulfate, palmitoylethyltrimonium methosulfate, stearoylethyltrimonium methosulfate, carnitine, palmitoylcarnitine, a mixture thereof, or similar compounds.In a frequently desired embodiment, the trimonium compound used is an alkyltrimonium compound comprising cetrimonium chloride, cetrimonium bromide, mitrimonium chloride, mitrimonium bromide, behentrimonium methosulfate, cocotrimonium methosulfate, behentrimonium chloride, behentrimonium bromide, steartrimonium chloride, steartrimonium bromide, laurtrimonium chloride, laurtrimonium bromide, or a mixture thereof. In another embodiment of the invention, the cationic surfactant used comprises cetrimonium chloride, cetrimonium bromide, mitrimonium chloride, mitrimonium bromide, behentrimonium methosulfate, cocotrimonium methosulfate, or a mixture thereof. In yet another embodiment of the invention, the cationic surfactant comprises cetrimonium chloride, cetrimonium bromide, or a mixture thereof. Even in another additional form, the cationic surfactant comprises cetrimonium chloride.To avoid any doubt, the cationic surfactant used in the present invention may consist essentially of any combination of the surfactants mentioned above. Regarding the cationic surfactant comprising a dimonium compound, said compound includes LOCO ίη / ZZΖΠZ / E / YΙΛΙ dialkyldimonium compounds such as distearyldimonium chloride, didecyldimonium chloride, dicodimonium chloride, a mixture thereof or similar compounds. Other suitable dimonium compounds include benzethonium chloride and / or benzalkonium chloride. The polyquaternium materials suitable for use as a cationic surfactant in the present invention include polyquaternium-6, polyquaternium-7, polyquaternium-16, polyquaternium-32, polyquaternium-37, polyquaternium-39, polyquaternium-45, polyquaternium-48, polyquaternium-53, acrylamidepropyltrimonium chloride / acrylate copolymer (or acrylamide), a mixture thereof or similar materials. The cationic surfactant used in the present invention is often at least 50% by weight of the trimonium and / or dimonium compound. In one embodiment of the invention, the cationic surfactant used in the present invention is at least 70% by weight of the trimonium and / or dimonium compound. In yet another embodiment of the invention, the cationic surfactant is at least 85 to 100% by weight of the trimonium compound, the dimonium compound, or both. In a further embodiment of the invention, the cationic surfactant is 90 to 100% by weight of the trimonium compound, the dimonium compound, or both. Still in another embodiment of the invention, the cationic surfactant is 95 to 100% by weight of the trimonium compound, the dimonium compound, or both. In yet another embodiment of the invention, the cationic surfactant is 98 to 100% by weight of the trimonium compound, preferably 100% by weight of the trimonium compound.In a preferred embodiment, the cationic surfactant used in the present invention is 90 to 100% by weight cetrimonium chloride, and more preferably 98 to 100% by weight cetrimonium chloride, and most preferably 100% by weight cetrimonium chloride. As noted above, when the total surfactant in the composition is more than 4.5% by weight and the cationic surfactant in the composition includes a combination of both cetrimonium chloride and benzalkonium chloride, the benzalkonium chloride constitutes at least 16.5% by weight of the total weight of the combination. In one embodiment of the invention, when the total surfactant in the composition is more than 5% by weight and the cationic surfactant in the composition includes a combination of both cetrimonium chloride and benzalkonium chloride, the benzalkonium chloride constitutes at least 16.5% by weight of the combination, and preferably at least 18%, and more preferably from 20 to 60% (even more preferably from 30 to 55%) by weight of the combination. In another embodiment, when the total surfactant in the composition is more than 5% by weight, the cationic surfactant in the composition includes a combination of both cetrimonium chloride and benzalkonium chloride, the benzalkonium chloride constitutes at least 16.5% by weight of the combination, and preferably at least 18%, and more preferably from 20 to 60% (even more preferably from 30 to 55%) by weight of the combination.65% (preferably more than 6%) by weight and the cationic surfactant in the composition includes a combination of both cetrimonium chloride and benzalkonium chloride, the benzalkonium chloride constituting at least 16.5% by weight of the combination, and preferably at least 18% by weight of the combination and more preferably 20 to 30% by weight of the combination. The amount of cationic surfactant (i.e., trimonium, dimonium, and / or polyquaternium cationic surfactant) used in the composition of the present invention is typically from 0.007 to 18%, and preferably from 0.01 to 13%, and more preferably from 0.05 to 10% by weight, based on the total weight of the composition and including all variations therein. In one embodiment of the invention, the cationic surfactant constitutes from 0.07 to 4% by weight of the composition. In another embodiment, the cationic surfactant constitutes from 0.07 to 3% by weight of the composition. In yet another embodiment of the invention, the cationic surfactant constitutes from 0.08 to 1% by weight of the composition. Still another embodiment, the cationic surfactant constitutes from 0.07 to 0.8% by weight of the composition. LOCO ίη / ZZΖΠZ / E / YΙΛΙ In another modality, the cationic surfactant constitutes 0.08 to 0.4% by weight of the composition. When both trimonium and dimonium surfactants are used, they are often used in a weight ratio of 1:99 to 99:1, and preferably 15:85 to 85:15, and more preferably 30:70 to 70:30, provided that when the total surfactant in the composition is more than 4.5% by weight and the cationic surfactant in the composition includes a combination of both cetrimonium chloride and benzalkonium chloride, the benzalkonium chloride constitutes at least 16.5% by weight of the combination. In another embodiment of the invention, the cationic surfactant used in the present invention is at least 70%, and preferably at least 80%, and more preferably at least 90% by weight of trimonium compound. In yet another embodiment, 92% to 100% by weight of all the cationic surfactant in the composition is trimonium compound. In another embodiment, 95% to 100% by weight of all the cationic surfactant is trimonium compound. Still another embodiment, 100% by weight of the cationic surfactant present in the composition of the present invention is trimonium compound. Still in another preferred embodiment, the composition of the present invention has less than 0.3% and preferably less than 0.2% by weight of benzalkonium chloride and / or benzethonium chloride, and preferably without (0.0% by weight) benzalkonium chloride and / or benzethonium chloride. In yet another embodiment of the invention, the dimonium and / or trimonium compound (more preferably cetrimonium chloride) constitutes at least 4%, and preferably at least 4.5%, and more preferably at least 5% by weight of the total weight of the surfactant in the disinfectant composition. Typically, water constitutes at least 80% by weight of the composition, and preferably at least 82% by weight of the composition, and more preferably at least 84% by weight of the disinfectant composition. In one embodiment of the invention, water constitutes 85% to 99.5%, and preferably 87% to 98.8%, and more preferably 89% to 97% by weight of the composition, including all variations therein. The disinfectant composition of the present invention is substantially free of ethanol (i.e., less than 10% by weight) and, preferably, comprises less than 6% by weight of ethanol and, more preferably, from 2.5% to 5.5% by weight of ethanol. In one embodiment of the invention, the composition of the present invention may have less than 1% by weight of ethanol. In another desired embodiment, the composition may have no ethanol (0.0% by weight). Additionally, excluding ethanol and excluding diols and polyols, the composition of the present invention comprises less than 8% and, preferably, less than 6.5% and, more preferably, less than 5% by weight of aliphatic alcohol. In yet another embodiment of the invention, the disinfectant composition of the present invention may comprise from 0.001% to 2.5% by weight of aliphatic alcohol or have no aliphatic alcohol (0.0% by weight). It is within the scope of this invention to include optional surfactants in addition to the cationic surfactants described herein. The optional surfactants may include those that are amphoteric (which, depending on the pH, may be zwitterionic). Illustrative optional amphoteric surfactants suitable for general use include sodium acylamphoacetates, sodium acylamphopropionates, disodium acylamphodiacetates, and disodium acylamphodiacetates, and amphodipropionates where the acyl group (i.e., the alkanoyl group) may comprise a C7-C18 alkyl portion. Illustrative examples of amphoteric surfactants that may be used include sodium lauroamphoacetate and sodium cocoamphoacetate. LOCO ίη / ΖΖΠΖ / Ε / ΥΙΛΙ sodium lauroamphoacetate, sodium cocoamphoacetate, a mixture thereof or the like. Regarding the zwitterionic surfactants that may optionally be used in the disinfectant composition of the present invention, these surfactants typically include at least one acid group. This acid group may be a carboxylic or sulfonic acid group. They often include quaternary nitrogen and, therefore, may be quaternary amino acids. In general, they must include an alkyl or alkenyl group of 7 to 18 carbon atoms and generally conform to a general structural formula: R1¿-C(O)-NH(CH2)q-]r-NÚRW)AB where R1 is alkyl or alkenyl of 7 to 18 carbon atoms; R2 and R3 are each independently alkyl, hydroxyalkyl or carboxyalkyl of 1 to 3 carbon atoms; q is from 2 to 4; r is 0 to 1; A is alkylene of 1 to 3 carbon atoms optionally substituted with hydroxyl, and B is -CO2- or -SO3-. Suitable zwitterionic surfactants for use in the present invention and within the above general formula include simple betaines of the formula: R1-N+(R2)(R3)-CH2CO2y amido betaines of the formula: R1-CONH(CH2)t-N+-(R2)(R3)CH2CO2 where t is 2 or 3. In both formulas, R1, R2, and R3 are as defined above. R1 can be, in particular, a mixture of O2 and Cu alkyl groups derived from coconut oil such that at least half, preferably at least three-quarters, of the R1 groups have 10 to 14 carbon atoms. R2 and R3 are preferably methyl. Another possibility is that the zwitterionic surfactant is a sulfobetaine of the formula: R1-N+(R2)(R3)-(CH2)3SO3· R1-CONH(CH2)u-N+(R2)(R3)-(CH2)3SO3 where u is 2 or 3, or variants of those in which -(CH2)3SO3 is replaced by -CH2C(OH)(H)CH2SO3-. In these formulas, R1, R2 and R3 are as defined above. Illustrative examples of zwitterionic surfactants suitable for optional use include betaines such as cocodimethylcarboxymethylbetaine, cocoamidopropylbetaine, and laurylamidopropylbetaine. An additional suitable zwitterionic surfactant includes cocoamidopropylsultaine. Such surfactants are commercially available from suppliers such as Stepan Company, and it is within the scope of the invention to optionally employ mixtures thereof. The nonionic surfactants that may optionally be used in the disinfectant composition of the present invention include, in particular, the reaction products of compounds having a hydrophobic group and a reactive hydrogen atom, for example, aliphatic alcohols, acids, amides, or alkylphenols with alkylene oxides, especially ethylene oxide, either alone or with propylene oxide. The specific nonionic surfactants are ethylene oxide-alkylphenol condensates (Ce-C22), condensation products of linear or branched primary or secondary aliphatic alcohols (Ce-Cis) with ethylene oxide, and products prepared by condensation of ethylene oxide with the products of LOCO Ln / Zznz / E / YIAI reaction of propylene oxide and ethylenediamine. Other non-ionic surfactants include long-chain tertiary amine oxides, long-chain tertiary phosphine oxides, dialkyl oxides, or the like. In one embodiment of the invention, optional nonionic surfactants include fatty acid / alcohol ethoxylates having the following structures: a) HOCH2(CH2)s(CH2CH2O)vH or b) HOOC(CH2)c(CH2CH2O)dH; where s and v are each independently integers up to 18; and c and d are each independently integers of 1 or greater. In one embodiment of the invention, s and v are each independently from 6 to 18; c and d are each independently from 1 to 30. Other options for nonionic surfactants include those having the formula HOOC(CH2)i-CH=CH(CH2)k(CH2CH2O)zH, where i and k are each independently from 5 to 15; and z is from 5 to 50. In another embodiment of the invention, i and k are each independently from 6 to 12. yz is from 15 to 35. The optional nonionic surfactant may also include a sugar amide, such as a polysaccharide amide. Specifically, the surfactant may be one of the lactobionamides described in U.S. Patent No. 5,389,279 to Au et al., entitled “Compositions Comprising Nonionic Glycolipid Surfactants,” issued February 14, 1995, which is incorporated herein by reference, or it may be one of the sugar amides described in U.S. Patent No. 5,009,814 to Kelkenberg, entitled “Use of N-Poly Hydroxyalkyl Fatty Acid Amides as Thickening Agents for Liquid Aqueous Surfactant Systems,” issued April 23, 1991, which is incorporated herein by reference. Still other optional non-ionic surfactants that can be used in the surfactant system and end-use composition of the present invention include non-ionic glucamides such as lauroylmethylglucamide, myristoylmethylglucamide, cocoylmethylglucamide, capryloyl / caproylmethylglucamide, girasolylmethylglucamide, or mixtures thereof or similar. Other optional non-ionic surfactants suitable for use include polyglycerol esters such as polyglycerol-10 caprylate, polyglycerol-10 caprate, polyglycerol-10 laurate, polyglycerol-10 myristate, polyglycerol-10 palmitate, polyglycerol-10 stearate, polyglycerol-10 oleate, polyglycerol-10 cocoate, or a mixture thereof. In another embodiment of the invention, the nonionic surfactant used may optionally include surfactants formed by the ethoxylation of sorbitan prior to the addition of a fatty acid. These include polysorbate 20, 60, and 80 (e.g., sold under the names Alkest® and Tween 20, 60, and 80, commercially available from suppliers such as Oxiteno and Croda International, respectively), as well as PEG-6 caprylic / capric glyceride (e.g., sold under the names Softigen® and Glycerox™, commercially available from IOI Oleo and Croda International, respectively). Other frequently desired nonionic surfactants include alkyl polyglucosides such as cocoyl glucoside, decyl glucoside, hydroxystearyl glucoside, cetearyl glucoside, lauryl glucoside, cetearylisononanoate, cetearth-20, cetearyl alcohol, glyceryl stearate, ceteareth-12, or a mixture thereof. Optional cationic surfactants suitable for use in the disinfectant composition of the present invention include heterocyclic ammonium salts such as cetyl chloride or stearylpyridinium chloride, alkylamidoethylpyrrylinidium methyl sulfate, and lapyrium chloride. Tetralkylammonium salts are another useful class of cationic surfactants suitable for use. Examples include cetyl chloride or bromide, stearyltrimethylammonium chloride or bromide, and palm trimethylammonium halides. LOCO Ln / Zznz / E / YIAI or hydrogenated tallow; behenyltrimethylammonium halides or methyl sulfates; decylisononyldimethylammonium halides; disebo (or distearyl)dimethylammonium halides and behenyldimethylammonium chloride. Other types of cationic surfactants that can be used include various ethoxylated quaternary amines and quaternary esters. Examples include PEG-5 stearylammonium lactate (e.g., Genamin KSL manufactured by Clariant), PEG-2 coconut ammonium chloride, PEG-15 hydrogenated tallow ammonium chloride, PEG-15 stearyl ammonium chloride, dipalmitoyleneethylmethylammonium chloride, dipalmitoylenehydroxyethylmethyl sulfate, and stearylamidopropyldimethylamine lactate. Other useful cationic surfactants suitable for use include quaternized hydrolysates of silk, wheat, and keratin proteins, and it is within the scope of the invention to use mixtures of the aforementioned cationic surfactants. If used, the optional surfactants collectively and typically constitute no more than 10.0% (often preferably no more than 8%) by weight of the disinfectant composition. When present, the optional surfactants preferably constitute no more than 5% by weight of the disinfectant composition. They often constitute from 0.001 to 4.5% and, more typically, from 0.01 to 4.0% by weight of the disinfectant composition, including all variations therein. In one embodiment of the invention, the optional surfactant constitutes from 0.1 to 2% by weight of the disinfectant composition. In another embodiment of the invention, the optional surfactant used is a nonionic surfactant constituting from 0.0 to 4%, and preferably from 0.1 to 2%, and more preferably from 0.3 to 1.5% by weight of the composition, including all variations therein. In yet another embodiment of the invention, only a nonionic surfactant is used as an optional surfactant. Preferably, the nonionic surfactant used is a polysorbate, PEG-6 caprylic / capric glyceride, an alkyl polyglucoside, or a mixture thereof. Still in another form, lauramine oxide is a surfactant used in the composition of the present invention from 0.1 to 10% and preferably from 0.2 to 8% and more preferably from 0.5 to 5% by weight of the composition. The disinfectant composition of the present invention comprises less than 0.5% and, preferably, less than 0.1% by weight of anionic surfactant and, more preferably, no anionic surfactant (0.0% by weight) such as sodium lauryl sulfate, sodium laureth sulfate, and / or sodium pareth sulfate. Therefore, the most preferred disinfectant composition of the present invention is sulfate-free. The pH of the disinfectant composition of the present invention is typically from 3.0 to 8.2, preferably from 3.1 to 7.5, and more preferably from 3.2 to 7.0. In one embodiment of the invention, the pH of the disinfectant composition is from 3.3 to 6.5, and preferably from 3.3 to 5.5. Suitable pH adjusters may be used to modify the pH of the disinfectant composition of this invention. Such pH adjusters include triethylamine, NaOH, KOH, H₂SO₄, HCl, CeH₂O₅ (i.e., citric acid), or a mixture thereof. Buffers, such as potassium oxide, for pH stabilization are also suitable. The pH of the composition is evaluated using conventional instrumentation such as a commercially available Thermo Scientific® pH meter. As for optional skin-beneficial agents, these can be water-soluble and / or oil-soluble, and water-soluble is preferred. Generally, humectants, such as water-soluble polyols, are desirable. LOCO ίη / ZZΖΠZ / E / YΙΛΙ water. These include sorbitol, glycerol (or glycerin), mannitol, xylitol, maltitol, or a mixture thereof. Other humectants include propylene glycol, dipropylene glycol, polypropylene glycol (e.g., PPG-9), polyethylene glycol, hydroxypropylsorbitol, hexylene glycol, 1,3-butylene glycol, 1,2-octanediol, 1,2-hexanediol, isoprene glycol, 1,2,6-hexantriol, ethoxylated glycerol, propoxylated glycerol, and mixtures thereof. The most preferred is glycerin, propylene glycol, or a mixture thereof. In one embodiment of the invention, the polyol used is at least 50% by weight of glycerol, based on the total weight of polyol used in the disinfectant composition. In another embodiment of the invention, the polyol used is a mixture of glycerol and hexylene glycol, in a weight ratio of 1:5 to 5:1, and preferably, 4:1 to 1:4, and more preferably, 3:1 to 1:3, including all the proportions included therein. Water-soluble wetting agents are suitable for optional use. These include dicaprylyl carbonate as well as substituted ureas such as hydroxymethylurea, hydroxyethylurea, hydroxypropylurea; bis(hydroxymethyl)urea; bis(hydroxyethyl)urea; bis(hydroxypropyl)urea; N,N'-dihydroxymethylurea; N,N'-dihydroxyethylurea; N,N'-dl-hydroxypropylurea; N,N,N'-tl-hydroxyethylurea; tetra(hydroxymethyl)urea; tetra(hydroxyethyl)urea; tetra(hydroxypropylurea; N-methyl, N'-hydroxyethylurea; N-ethyl-N'-hydroxyethylurea; N-hydroxypropyl-N'-hydroxyethylurea; and N,N'-dimethyl-N-hydroxyethylurea, or a mixture thereof. When the term hydroxypropyl occurs, it means generically for the radicals 3-hydroxy-n-propyl, 2-hydroxy-n-propyl, 3-hydroxy-i-propyl, or 2-hydroxy-ipropyl. The preferred option for use is hydroxyethylurea. It is available as a 50% aqueous liquid from Nouryon under the trade name Hydrovance®. Other optional water-soluble skin-beneficial agents suitable for use in the disinfectant composition of this invention include acids, such as amino acids like arginine, valine, or histidine. Vitamins such as vitamin B2, picolinamide, niacinamide (vitamin B3), panthenol (vitamin B5), vitamin B1, vitamin C, mixtures thereof, or similar substances may be used. Derivatives, and especially water-soluble derivatives, of these vitamins may also be employed. For example, vitamin C derivatives such as ascorbyl tetraisopalmitate, magnesium ascorbyl phosphate, and ascorbyl glucoside may be used alone or in combination.Other suitable skin-beneficial agents include hyaluronic acid and its salts (such as Na+ and K+ salts), 4-ethylresorcinol, and extracts such as sage, aloe vera, green tea, sugar cane, citrus, grape seed, thyme, chamomile, wild parsley, cucumber, licorice, rosemary extract, or a mixture thereof. Water-soluble sunscreens such as ensulisole, as well as electrolytes such as NaCl and / or KCl, may also be used. The total amount of optional water-soluble beneficial agents (including mixtures) when present in the composition of the invention may vary from 0.0001 to 10%, preferably from 0.001 to 6.5%, and more preferably from 0.01 to 3.5% by weight, based on the total weight of the disinfectant composition and including all variations therein. In a preferred embodiment of the invention, glycerol can be used in the disinfectant composition in an amount from 0.05 to 2.0%, and a hydroxyethyl urea-based humectant, such as Hydrovance, may be optionally used in an amount of 0.05 to 1.5%, and hexylene glycol is optionally used in an amount of 1 to 4% by weight, based on the total weight of the composition and including all variations included therein. In a frequently desired embodiment, the disinfectant composition of the present invention comprises from 0.5 to 10% and preferably from 0.6 to 7% and more preferably from 0.8 to 3.5% by weight of LQCQ ίη / ZZΖΠZ / E / YΙΛΙ niacinamide (for a longer-lasting antimicrobial benefit) based on the total weight of the disinfectant composition. In yet another formulation, niacinamide is present from 0.7 to 1.4% by weight of the composition. It is also within the scope of the invention to optionally include beneficial oil-soluble agents. Illustrative examples of the types of beneficial oil-soluble agents that may be optionally used in the disinfectant composition of this invention include components such as stearic acid, vitamins such as vitamins A, D, E, and K (and their oil-soluble derivatives), sunscreens such as ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenol triazine, 2-ethylhexyl-2-cyano-3,3-diphenyl-2-propanoic acid, drometrizoltrisiloxane, 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate, 2-ethylhexyl-2-hydroxybenzoate, or a mixture thereof. Other suitable optional oil-soluble beneficial agents include resorcinols such as 4-hexylresorcinol, 4-phenylethylresorcinol, 4-cyclopentylresorcinol, 4-cyclohexylresorcinol, 4-isopropylresorcinol, or a mixture thereof. 5-Substituted resorcinols such as 4-cyclohexyl-5-methylbenzene-1,3-diol, 4-isopropyl-5-methylbenzene-1,3-diol, mixtures thereof, or similar compounds may also be used. The 5-substituted resorcinols and their synthesis are described in the commonly assigned U.S. Published Patent Application No. 2016 / 0000669A1. Other beneficial oil-soluble agents suitable for use include omega-3 fatty acids, omega-6 fatty acids, climbazole, magnolol, honokiol, farnesol, ursolic acid, myristic acid, geranyl geraniol, oleyl betaine, cocoylhydroxyethylimidazoline, hexanoylsphingosine, 12-hydroxystearic acid, petroselinic acid, conjugated linoleic acid, stearic acid, palmitic acid, lauric acid, terpineol, essential components of thymol, and the selected dissolving aids of limonene, pinene, camphene, cymene, citronellol, citronellal, geraniol, nerol, linalool, rhodinol, borneol, isoborneol, menthone, camphor, safrole, isosafrole, eugenol, isoeugenol, tea tree oil, eucalyptus oil, peppermint oil, neem oil, and grass oil. lemon oil, orange oil, bergamot oil, mixtures of the same or similar. Another optional oil-soluble beneficial agent that may be used is a retinoic acid precursor. In one embodiment of the invention, the retinoic acid precursor is retinol, retinal, retinyl propionate, retinyl palmitate, retinyl acetate, or a mixture thereof. Typically, retinyl propionate, retinyl palmitate, and mixtures thereof are preferred. Yet another suitable retinoic acid precursor is hydroxyanasatil retinoate, commercially available under the name Retextra® as supplied by Molecular Design International. It may be used in a mixture with the oil-soluble beneficial agents described herein. When an optional oil-soluble beneficial agent (i.e., 0.0 to 1.5% by weight) is used in the disinfectant composition of the invention, it normally constitutes 0.001 to 1.3%, and in another embodiment, 0.05 to 1.2%, and in yet another embodiment, 0.1 to 0.5% by weight of the total weight of the end-use composition, including all variations therein. Film-forming agents may be used in the compositions of the present invention. While optional, such agents can aid in the composition's adhesion to the surface to which it is applied. Film-forming agents include those with hydrophilic properties and include materials comprising polyvinylpyrrolidone (PVP), acrylates, acrylamides, and copolymers of the LOCO Ln / Zznz / E / YIAI elimination of 3 in less than 2 minutes, and preferably at least one elimination record of 4.7 in less than 1.2 minutes after application (i.e., contact) with a bacterial colony containing at least one of Staphylococcus aureus, Escherichia coli, and Cutibacterium acnes. In addition, viral inactivation of at least 2 in less than 3 minutes after topical application to a surface with adenovirus was observed, and preferably at least 2.4 in less than 1.5 minutes after topical application to the adenovirus. The disinfectant composition of this invention can be provided as micellar water (a surfactant that forms micelles in water, preferably a cationic surfactant) that remarkably provides excellent reduction of antimicrobial and viral activity upon contact with a surface. In the preparation of the precursor or disinfectant composition of the invention, the ingredients are mixed with moderate shear under atmospheric conditions and at a temperature of 20 to 65°C. Depending on the desired volume, the precursor (containing less than 15% water by weight) should be mixed with water followed by moderate agitation to produce the desired disinfectant composition. Normally, the viscosity of the disinfectant composition will be less than 30,000 mPa s (30,000 cps). Often, the viscosity of the disinfectant composition will be from 0 to 25,000 mPa s (0 to 18,000 mPa s), and preferably from 0 to 14,000 mPa s (0 to 14,000 cps), including all variations therein. In one embodiment of the invention, the viscosity of the disinfectant composition is from 1 to 3,000 mPa s (1 to 3,000 cps), and in yet another embodiment, the viscosity of the disinfectant composition is from 1 to 2,000 mPa s (1 to 2,000 cps). Still in another embodiment, the viscosity of the disinfectant composition is from 1 to 250 mPa s (1 to 250 cps). To adjust the viscosity of the disinfectant composition, it is within the scope of the invention to optionally include thickening agents. Thickeners classified as polysaccharides are optionally suitable for use in the disinfectant composition of the present invention. Examples include fibers, starches, natural / synthetic gums, and cellulosic agents. Representative starches are chemically modified starches such as sodium starch hydroxypropyl phosphate and aluminum starch octenylsuccinate. Tapioca starch is often preferred, as is maltodextrin. Suitable gums include xanthan, tara, sclerotium, pectin, karaya, gum arabic, agar, guar (including Acacia senegal guar), carrageenan, alginate, and combinations thereof.Suitable cellulosic materials include hydroxypropyl cellulose, hydroxypropyl methylcellulose, ethylcellulose, sodium carboxymethylcellulose (cellulose gum / carboxymethylcellulose), and cellulose (e.g., cellulose microfibrils, cellulose nanocrystals, or microcrystalline cellulose). Fatty alcohols such as cetyl, cetearyl, and stearyl alcohols can also be used. Sources of cellulose microfibrils include secondary cell wall materials (e.g., wood pulp, cotton), bacterial cellulose, and primary cell wall materials.Preferably, the source of primary cell wall material is selected from parenchyma tissue of fruits, roots, bulbs, tubers, seeds, leaves, and combinations thereof; more preferably, it is selected from citrus fruits, tomato fruits, peach fruits, pumpkin fruits, kiwi fruits, apple fruits, mango fruits, sugar beet, beetroot, turnip, parsnip, corn, oats, wheat, beans, and combinations thereof; and even more preferably, it is selected from citrus fruits, tomato fruits, and combinations thereof. A more preferred source of primary cell wall material is... LOCO ίη / ZZΖΠZ / E / YΙΛΙ citrus fruit parenchyma tissue. Citrus fibers, such as those available from Herbacel® as AQ Plus, can also be used as a source of cellulose microfibrils. Cellulose sources can be surface-modified by any of the known methods, including those described in Colloidal Polymer Science, Kalia et al., “Nanofibrillated cellulose: surface modification and potential applications” (2014), Vol 292, pages 5-31. Synthetic polymers are another class of effective thickening agents. This category includes crosslinked polyacrylates such as carbomers, acrylate copolymers, acrylate / acrylate (C10-C30) alkylacrylate crosslinks, polyacrylamides such as Sepigel® 305, and taurate copolymers such as Simulgel® EG and Aristoflex® AVC. These copolymers are identified by their respective INCI names, such as Sodium Acrylate / Sodium Acryloyldimethyltaurate and Acryloyldimethyltaurate / Vinylpyrrolidone Copolymer. Another preferred synthetic polymer suitable for thickening is a commercially available acrylate-based polymer from Seppic, sold under the name Simulgel INS100. Calcium carbonate, fumed silica, and magnesium aluminum silicate can also be used. The amounts of thickening agent, when used, can vary from 0.001 to 5% by weight of the disinfectant composition. Maltodextrin, xanthan gum, and carboxymethylcellulose are frequently preferred thickening agents. Other often desirable thickening agents include dilinoleyl / dimethyl carbonate copolymer, stearylalkonium hectorite, cetyl fatty alcohols (cetearyl, stearyl), tara gum, pentaerythrityl tetrastearate, or a mixture thereof. Regarding packaging, the disinfectant composition of the present invention can be packaged in a roll-on bottle, a bottle with a self-foaming mechanism / pump, or provided as an impregnating wetting agent on cotton swabs, wipes, moist wipes, cosmetic substrate sheets (such as those described in US 6,294,182 B1), or the like. As the viscosity increases with the thickening agent, the disinfectant composition can be provided to consumers in a squeezable bottle, a pump bottle, or a tube as a gel composition. The roll-on bottle can also be made of metal, and the disinfectant composition can be delivered via conventional aerosol packaging technologies, including those using bag air discharge cylinders, mechanisms, and actuators.It is also within the scope of the invention to include foaming agents (e.g., zwitterionic and / or amphoteric surfactants) so that the disinfectant composition can be dispensed as a foam. In one embodiment of the invention, the disinfectant composition is supplied in a standard roll-on bottle with a spray actuator and is sprayed onto the surface to be disinfected, particularly the skin. The disinfectant composition of the invention is particularly useful for preventing adverse skin reactions (such as the development of acne) caused by microbes that collect under personal protective equipment (including trousers, gowns, and especially face masks). It is therefore advisable to apply the disinfectant composition of the present invention to the skin before donning personal protective equipment (and even throughout the day while wearing personal protective equipment). The disinfectant composition of the invention shall be supplied with instructions for applying (preferably spraying) the composition onto a surface, such as skin, to eliminate bacteria and reduce viral activity. Preferably, the precursor shall be provided in biodegradable packaging and the container LOCO Ln / Zznz / E / YIAI used preferably is refillable or reusable, biodegradable and / or at least 50%, and preferably at least 100% made from post-consumer recycled resin. The following examples are provided to further illustrate an understanding of the invention. The examples are not intended to limit the scope of the claims. Examples The ingredients listed in the tables were mixed using moderate shear under atmospheric conditions at a temperature set at 30°C. The resulting formulas were recovered and evaluated. The tests were conducted by experts familiar with the identified ASTM methods, as summarized below. ASTM E2783-11 (Reapproved in 2016): Test Method Used to Evaluate Antimicrobial Activity of Miscible Compounds. A dilution / aliquot of the test material was brought into contact with a known population of test organisms (Staphylococcus aureus and Escherichia coli) for the specified time periods as defined below and at a temperature of 25°C. The activity of the test material was extinguished at the specified sampling intervals using an appropriate neutralization technique with a solution of Tween 80 (10%) and lecithin (1%). The test material / organisms were neutralized at the identified times and the surviving microorganisms were listed. The percentage and logw reduction were calculated from an initial microbial population. ASTM E1052-20: Test Method Used to Evaluate Microbicides Against Viruses in Suspension. Virus suspension was added to nine parts of test substance, a suspension loaded with adenovirus. The resulting mixture was maintained at 25°C for the identified contact times and then tested on viable virus in a host system. For a control, one part of virus was added to nine parts of buffer harmless to the virus and any host cells. Cell culture, cytotoxicity, and viral susceptibility controls were included in each test. Example 1 The following disinfectant composition was prepared according to the invention. The trimonium compound used was cetrimonium chloride. The composition had a viscosity of approximately 100 mPa s (100 cps) and was applied to the panelists' hands via a spray bottle. The composition was mild and non-irritating after application. LQCQ ίη / ΖΖΠΖ / Ε / ΥΙΛΙ Ingredients by weight (%) active ingredient Water Remainder Natural Fragrance Extract 0.01 Sodium Chloride 0.01 D-Panthenol (75%) 0.01 Niacinamide 0.01 Sodium Ascorbyl Phosphate 0.01 Citric Acid 0.025 Humectant 1 Cetrimonium chloride 0.1 PEG-6-caprylic / capric glyceride 0.5 Cetylpyridinium chloride 0.02 Glycol 2.5 EDTA 0.05 Potassium chloride 0.01 Preservative 0.2 CRAZY ίη / ΖΖΠΖ / Ε / ΥΙΛΙ Example 2 The following disinfectant composition was prepared according to the invention. The trimonium compound used was cetrimonium chloride. The composition had a viscosity of approximately 100 mPa s (100 cps) and was impregnated into wipes / moistened cloths. The composition was gentle and non-irritating after application to the hands and face of panelists via wipes / moistened cloths. Ingredients Weight (%) Water Remainder Sodium citrate dihydrate 0.5 1,2-propanediol 1 Sodium benzoate 0.5 Glycerin 0.3 Humectant 0.1 Vitamin E acetate 0.01 Cetrimonium chloride 0.145 Non-ionic emulsifier 3.2 Citric acid 0.25 Example 3 Disinfectant Composition of the Invention with Fragrance Ingredients % by weight Water Remainder Tetrasodium EDTA 0.05 Sodium Chloride 0.01 Potassium Chloride 0.01 Panthenol 0.01 Niacinamide 0.01 Citric Acid 0.025 Hexylene glycol 2.5 Hydroxyethylurea 0.08 pH adjuster 0.001 Moisturizer 0.004 pH stabilizer 0.006 Glycerin 1.0 PEG-6-caprylic / capric glyceride 0.5 Cetrimonium chloride 0.1 Phenoxyethanol 0.2 Cetylpyridinium chloride 0.02 Propylene glycol 0.03 Sunscreen 0.006 Trideceth-9 0.07 PEG-40 Hydrogenated Castor Oil 0.07 Fragrance 0.05 LOCO Ln / Zznz / E / YIAI Example 4 Disinfectant composition of the invention, fragrance-free Ingredient INCI Name Ingredient % in Formula Water Remainder Tetrasodium EDTA 0.051 Sodium Chloride 0.01 Potassium Chloride 0.01 Panthenol 0.01 Niacinamide 0.01 Citric Acid 0.025 Hexylene Glycol 2.5 Hydroxyethylurea 0.08 Ethanolamine 0.001 Humectant 0.006 Ammonium Lactate 0.004 Glycerin 1.0 PEG-6-Caprylic / Capric Glycerides 0.5 Cetrimonium Chloride 0.1 Phenoxyethanol 0.2000 Cetylpyridinium Chloride 0.02 Glycol 0.03 Example 5 Composition assessment LQCQ ίΠ / ΖΖηΖ / Ε / ΥΙΛΙ Fragrance-free disinfectant composition - Table A Example 4 Composition Repeat Test Organism: S. aureus ATCC6538 Logw Reduction - Contact Time (n=3) 30 seconds 60 seconds Average Reduction Average Reduction Logw (%) Percentage Logw (%) Percentage Logw (%) Percentage Logw (%) Percentage 1 3.84 99.99 3.94 99.99 4.90 99.99 4.93 99.99 2 4.08 99.99 5.04 99.99 3 3.89 99.99 4.86 99.99 The data in Table A unexpectedly show an average logw reduction of 3.94, 99.99 percent reduction of S. aureus after 30 seconds of contact and an average logw reduction of 4.93, 99.99 percent reduction of S. aureus after 60 seconds of contact, even with 0.1% trimonium compound and more than 80% by weight water in the composition. Fragrance comprising Disinfectant Composition Table B Example 3 Composition Repeat Test Organism: E. coli ATCC25922 Logw Reduction - Contact Time (n=3) 30 seconds 60 seconds Average Reduction Average Reduction Logw (%) Percentage Logw (%) Percentage Logw (%) Percentage Logw (%) Percentage 1 5.83 99.99 5.53 99.99 >5.83 99.99 5.83 99.99 2 5.53 99.99 >5.83 99.99 3 5.23 99.99 5.83 99.99 The data in Table B unexpectedly show an average logw reduction of 5.53, 99.99 percent reduction of E. coli after 30 seconds of contact and an average logw reduction of 5.83, 99.99 percent reduction of E. coli after 60 seconds of contact, even with 0.1% trimonium compound and more than 80% by weight water in the composition. Fragrance comprising disinfectant composition Table C Example 3 Composition Repeat Test Organism: S. aureus ATCC6538 Log-io Reduction Contact Time (n=3) 30 seconds 60 seconds Average Reduction Average Reduction Logw (%) Percentage Logw (%) Percentage Logw (%) Percentage Logw (%) Percentage 1 3.83 99.99 3.91 99.99 4.84 99.99 4.82 99.99 2 3.91 99.99 4.91 99.99 3 3.99 99.99 4.70 99.99 CRAZY ίΠ / ΖΖηΖ / Ε / ΥΙΛΙ The data in Table C unexpectedly show an average logw reduction of 3.91,99.99 percent of S. aureus after 30 seconds of contact and an average logw reduction of 4.82,99.99 percent of S. aureus after 60 seconds of contact, even with 0.1% trimonium compound and more than 80% by weight water in the composition. Composition of Fragrance-Free Disinfectant Table D Example 4 Composition Repeat Test Organism: E. coli ATCC25922 Logw Reduction - Contact Time (n=3) 30 seconds 60 seconds Average Reduction Average Reduction Logw (%) Percentage Logw (%) Percentage Logw (%) Percentage Logw (%) Percentage 1 5.83 99.99 5.64 99.99 >5.83 99.99 >5.83 99.99 2 5.53 99.99 >5.83 99.99 3 5.55 99.99 >5.83 99.99 The data in Table D unexpectedly show an average log™ reduction of 5.64, 99.99 percent reduction of E. coli after 30 seconds of contact and an average logw reduction of 5.83, 99.99 percent reduction of E. coli after 60 seconds of contact, even with 0.1% trimonium compound and more than 80% by weight water in the composition. Table E Adenovirus Inactivation - 60 Seconds Control CTAB (0.05%) CTAB (0.1%) CPC (0.05%) CPC (0.1%) Logw TCID 50 / 0.1 mi 4.75 2.5 1.75 1.6 1.6 The data in Table E unexpectedly show that the trimonium compound (e.g., cetrimonium bromide (CTAB)) surprisingly had adenovirus inactivation by the logw TCID method comparable to that observed with cetylpyridinium chloride (CPC) at 60 seconds. Example 6 A composition similar to that prepared in Example 3 was prepared, except that 0.05% by weight of both benzalkonium chloride and didecyldimonium chloride was used instead of cetrimonium chloride. The data obtained using the ASTM tests mentioned above unexpectedly showed a Logw reduction of approximately 4.6, 99.99 percent reduction of E. coli after 10 seconds of contact and a Logw reduction of more than 5, 99.99 percent reduction of E. coli after 60 seconds of contact. The data also revealed a Logw reduction of approximately 4, 99.99 percent of S. aureus after 10 seconds of contact and a Logw reduction of approximately 4.9, 99.99 percent of S. aureus after 60 seconds of contact. Example 7 A composition similar to that prepared in Example 3 was prepared except that 0.15% by weight of benzalkonium chloride was used instead of cetrimonium chloride. Surprisingly, the composition had a reduction in Logw TCID viral inactivation of more than 2 in less than 3 minutes.

Claims

1. Use, as an antibacterial and antiviral disinfectant composition, of a composition comprising: a) at least 80% by weight of water; and b) a cationic surfactant wherein the composition is capable of providing a bacterial elimination record of at least 2 and a viral inactivation record of at least 2 in less than 3 minutes after topical application and further wherein the composition has less than 10% by weight of ethanol and where the total surfactant in the composition is more than 4.5% by weight and the cationic surfactant in the composition includes a combination of both cetrimonium chloride and benzalkonium chloride, the benzalkonium chloride constituting at least 16.5% by weight of the combination; wherein the composition has less than 0.3% by weight of benzalkonium chloride and / or benzethonium chloride; wherein the cationic surfactant is 95 to 100% by weight of trimonium compound, dimonium compound or both; wherein the composition comprises 0.0% by weight of aliphatic alcohol, excluding ethanol and not including diols and polyols; wherein the trimonium compound is an alkyltrimonium compound comprising cetrimonium chloride, cetrimonium bromide, mitrimonium chloride, mitrimonium bromide, behentrimonium methosulfate, cocotrimonium methosulfate, behentrimonium chloride, behentrimonium bromide, steartrimonium chloride, steartrimonium bromide, laurtrimonium chloride, laurtrimonium bromide or a mixture thereof, and wherein the dimonium compound is distearyldimonium chloride, didecyldimonium chloride, dicodimonium chloride, a mixture thereof or benzethonium chloride and / or benzalkonium chloride, and wherein the cationic surfactant constitutes from 0.08 to 0.4% by weight of the composition.

2. Use according to claim 1, wherein the cationic surfactant comprises cetrimonium chloride, cetrimonium bromide or a mixture thereof.

3. Use according to claim 1 or 2, wherein the cationic surfactant is cetrimonium chloride.

4. Use in accordance with any of claims 1 to 3, wherein the composition further comprises a non-ionic surfactant.

5. Use according to any of claims 1 to 4, wherein the composition comprises a polyol and the polyol is sorbitol, glycerol, mannitol, xylitol, maltitol, dipropylene glycol, polypropylene glycol, polyethylene glycol, hydroxypropylsorbitol, hexylene glycol, 1,3-butylene glycol, 1,2-octanediol, 1,2-hexanediol, isoprene glycol, 1,2,6-hexantriol, ethoxylated glycerol, propoxylated glycerol or a mixture thereof.

6. Use according to any of claims 1 to 5, wherein the composition further comprises omega-3 soluble fatty acids, omega-6 fatty acids, climbazole, magnolol, honokiol, farnesol, ursolic acid, myristic acid, geranylgeraniol, oleyl betaine, cocoylhydroxyethylimidazoline, hexanoylsphingosine, 12-hydroxystearic acid, petroselinic acid, conjugated linoleic acid, stearic acid, palmitic acid, lauric acid, terpineol, thymol essential components, the dissolving aid selected from limonene, pinene, camphene, cymene, citronellol, citronellal, geraniol, nerol, linalool, rhodinol, borneol, isoborneol, menthone, camphor, safrole, isosafrole, eugenol, isoeugenol, tea tree oil, eucalyptus oil, Peppermint oil, neem oil, lemongrass oil, orange oil, bergamot oil, or a mixture thereof. LOCO Ln / Zznz / E / YIAI 7. Use according to any of claims 1 to 6, wherein the composition comprises arginine, valine, histidine, vitamin B2, niacinamide (vitamin B3), vitamin B5, vitamin B1, vitamin C, ascorbyl tetraisopalmitate, magnesium ascorbyl phosphate, ascorbyl glucoside, hyaluronic acid and salts thereof, 4-ethylresorcinol, sage, aloe vera, green tea, sugar cane, citrus fruits, grape seed, thyme, chamomile, wild parsley, cucumber, licorice, rosemary, ensulizol, NaCl, KCl or a mixture thereof.

8. Use according to any of claims 1 to 7, wherein the composition comprises hydroxymethylurea, hydroxyethylurea, hydroxypropylurea; bis(hydroxymethyl)urea; bis(hydroxyethyl)urea; bis(hydroxypropyl)urea; N,N'-dihydroxymethylurea; N,N'-dihydroxyethylurea; N,N'-dihydroxypropylurea; N,N,N'-trihydroxyethylurea; tetra(hydroxymethyl)urea; tetra(hydroxyethyl)urea; tetra(hydroxypropyl)urea; N-methyl, N'-hydroxyethylurea; N-ethyl-N'-hydroxyethylurea; N-hydroxypropyl-N'-hydroxyethylurea and N,N'-dimethyl-N-hydroxyethylurea or a mixture thereof.

9. Use according to any of claims 1 to 8, wherein the composition further comprises eucalyptus oil, lavender oil, N,N-diethyl-meta-toluamide (DEET), octopirox (piroctone), zinc pyrithione, benzethonium chloride, benzalkonium chloride, chloroxylenol, triclosan, cetylpyridinium chloride, silver oxide, silver nitrate, silver sulfate, silver phosphate, silver carbonate, silver acetate, silver benzoate or a mixture thereof.

10. Use in accordance with any of claims 1 to 9, wherein the composition comprises at least 82% water.

11. Use according to any of claims 1 to 10, wherein the composition comprises 85 to 99.5% by weight of water and less than 5% by weight of ethanol.

12. Use according to any of claims 1 to 11, wherein the composition comprises glycerol and has a viscosity of less than 30 Pa s (30,000 cps).

13. Use according to any of claims 1 to 12, wherein the composition comprises a mosquito repellent, octopirox, zinc pyrithione, chloroxylenol, triclosan, cetylpyridinium chloride or a silver compound being a silver oxide, nitrate, sulfate, phosphate, carbonate, acetate, benzoate or a mixture thereof.

14. A composition characterized in that it comprises: a) at least 80% by weight of water; and b) a cationic surfactant wherein the composition is capable of providing a bacterial elimination record of at least 2 and a viral inactivation record of at least 2 in less than 3 minutes after topical application and further wherein the composition has less than 10% by weight of ethanol and where the total surfactant in the composition is more than 4.5% by weight and the cationic surfactant in the composition includes a combination of both cetrimonium chloride and benzalkonium chloride, the benzalkonium chloride constituting at least 16.5% by weight of the combination; wherein the composition has less than 0.3% by weight of benzalkonium chloride and / or benzethonium chloride; wherein the cationic surfactant is 95 to 100% by weight of trimonium compound, dimonium compound or both; wherein the composition comprises 0.0% by weight of aliphatic alcohol, excluding ethanol and not including diols and polyols; wherein the trimonium compound is an alkyltrimonium compound comprising cetrimonium chloride, cetrimonium bromide, mitrimonium chloride, mitrimonium bromide, behentrimonium methosulfate, cocotrimonium methosulfate, behentrimonium chloride, behentrimonium bromide, steartrimonium chloride, steartrimonium bromide, laurtrimonium chloride, laurtrimonium bromide or a mixture thereof, and wherein the dimonium compound is distearyldimonium chloride, didecyldimonium chloride, dicoodimonium chloride, a mixture thereof or benzethonium chloride and / or benzalkonium chloride, and wherein the cationic surfactant constitutes from 0.08 to 0.4% by weight of the composition, for use in a method for preventing adverse skin reactions such as the development of acne caused by microbes collected under personal protective equipment, comprising the step of applying the composition to the skin before donning the personal protective equipment.