Pharmaceutical composition comprising ticagrelor and acetylsalicylic acid, preparation process and uses thereof

Abstract

The present invention provides a pharmaceutical composition comprising ticagrelor at a dose of 90 mg, acetylsalicylic acid at a dose of 75 to 100 mg, at least one of a diluent, a binder, a wetting agent, a gluing agent, and a lubricant. The pharmaceutical composition of the present invention overcomes a number of significant technological challenges due to the physicochemical properties and the varying doses of each drug. This pharmaceutical composition is stable, making it safe and effective for the treatment and prevention of cardiovascular diseases. The invention also relates to a manufacturing process for this pharmaceutical composition.