A monoclonal antibody and a method of use for the treatment of lupus

NZ780818BActive Publication Date: 2026-09-01BIOCON LTD

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Patent Information

Application Number: NZ780818
Authority / Receiving Office: NZ · NZ
Patent Type: Patents
Current Assignee / Owner
Priority Date: 2016-10-21
Filing Date: 2017-10-17
Publication Date: 2026-09-01
Estimated Expiration: 2037-10-17

Application Information

Patent Timeline

21 Oct 2016

Priority

17 Oct 2017

Application

NZ780818

01 Sep 2026

Publication

NZ780818B

IPC: C07K16/18; A61K39/395

Inventors: MELARKODE, RAMAKRISHNAN; NAIR, PRADIP

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Abstract

The present invention relates to compositions and methods useful for the treatment of lupus using a humanized IgG1 anti-CD6 monoclonal antibody (T1h) that binds to the SRCR domain 1(D1) of CD6 without blocking the interaction of CD6 with the CD6 ligand Activated Leukocyte Cell Adhesion Molecule (ALCAM).

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