An Engineered Multi-component System for Identification and Characterisation of T-cell receptors, T-cell antigens and their functional interaction

NZ794221BActive Publication Date: 2026-09-01GENOVIE
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Patent Information

Application Number
NZ794221
Authority / Receiving Office
NZ · NZ
Patent Type
Patents
Current Assignee / Owner
Priority Date
2016-11-07
Filing Date
2017-11-07
Publication Date
2026-09-01
Estimated Expiration
2037-11-07

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Abstract

The present invention relates to a multicomponent system wherein a first component is an engineered TCR-presenting cell (eTPC), designated component A, wherein component A lacks endogenous surface expression of at least one family of analyte antigen presenting complexes (aAPX) and / or analyte antigenic molecule (aAM), and a second component is a genetic donor vector, designated component C, for delivery of ORF encoding analyte TCR chains.
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