Controllable transcription
NZ794568BActive Publication Date: 2026-09-01CAMBRIDGE ENTERPRISE LTD
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Patent Information
- Application Number
- NZ794568
- Authority / Receiving Office
- NZ · NZ
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2016-11-24
- Filing Date
- 2017-11-24
- Publication Date
- 2026-09-01
- Estimated Expiration
- 2037-11-24
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Abstract
The present invention relates to a stable method for introducing at least one inducible cassette into a cell, and permitting controllable transcription from within that inducible cassette. The method may be used for any cell type, from any eukaryotic organism, but has a particular application in the introduction of inducible cassettes into pluripotent stem cells, such as animal or human pluripotent stem cells (hPSCs). The inducible cassette is controllably inserted in such a way to ensure that the genetic material it contains is not silenced or subject to negative influences from the insertion site, and transcription of the genetic material is controlled.
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