Conjugation linkers containing 2,3-diaminosuccinyl group
NZ804426BActive Publication Date: 2026-09-29HANGZHOU DAC BIOTECH CO LTD
View PDF 0 Cites 0 Cited by
Patent Information
- Application Number
- NZ804426
- Authority / Receiving Office
- NZ · NZ
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2018-10-12
- Publication Date
- 2026-09-29
- Estimated Expiration
- 2038-10-12
Smart Images
Figure 00000169_0000 
Figure 00000169_0001 
Figure 00000169_0002
Abstract
Provided is a conjugate of a cytotoxic drug / molecule to a cell-binding molecule with a bis-linker (adual-linker) containing a 2, 3-diaminosuccinyl group. It also relates to preparation of the conjugate of a cytotoxic drug / molecule to a cell-binding molecule with the bis-linker, particularly when the drug having functional groups of amino, hydroxyl, diamino, amino-hydroxyl, dihydroxyl, carboxyl, hydrazine, aldehyde and thiol for conjugation with the bis-linker in a specific manner, as well as the therapeutic use of the conjugates.
Need to check novelty before this filing date? Find Prior Art