Inhibitors of APOL1 and methods of using same
NZ835598APending Publication Date: 2026-08-28VERTEX PHARMACEUTICALS INC
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Patent Information
- Application Number
- NZ835598
- Authority / Receiving Office
- NZ · NZ
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2020-08-26
- Filing Date
- 2021-08-26
- Publication Date
- 2026-08-28
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Figure 1_ABST
Abstract
The disclosure provides at least one entity chosen from compounds of Formula I, a tautomer thereof, a deuterated derivative of that compound or tautomer, and a pharmaceutically acceptable salt of any of the foregoing, compositions comprising the same, and methods of using the same, including uses in treating APOL1-mediated diseases, including pancreatic cancer, focal segmental glomerulosclerosis (FSGS), and / or non-diabetic kidney disease (NDKD).
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