Methods of treating sensitized patients with hypoimmunogenic cells, and associated methods and compositions
NZ835957APending Publication Date: 2026-08-28SANA BIOTECHNOLOGY INC
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Patent Information
- Application Number
- NZ835957
- Authority / Receiving Office
- NZ · NZ
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2021-04-14
- Filing Date
- 2021-08-12
- Publication Date
- 2026-08-28
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Abstract
Disclosed herein are hypoimmunogenic cells for administering to a sensitized patient. In some instances, the patient is sensitized from a previous pregnancy or a previous transplant. In some embodiments, the cells exogenously express CD47 proteins and exhibit reduced expression of MHC class I proteins, MHC class II proteins, or both.
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