Continuous virus retentive filtration
NZ837075APending Publication Date: 2026-09-25REGENERON PHARMACEUTICALS INC
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Patent Information
- Application Number
- NZ837075
- Authority / Receiving Office
- NZ · NZ
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2020-11-05
- Filing Date
- 2021-10-01
- Publication Date
- 2026-09-25
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Abstract
The present application provides methods and systems for viral clearance for purifying an antibody from a sample comprising one or more impurities including viral particles. The method is conducted in a system which includes a hydrophobic interaction chromatography (HIC) column and a virus retentive filtration (VRF) system. The HIC column and the VRF system are connected inline in a continuous processing system, and the VRF system comprises at least two filter trains in parallel.
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