Specificity enchanced bispecific antibody (SEBA)
NZ837260APending Publication Date: 2026-09-25SYSTIMMUNE INC
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Patent Information
- Application Number
- NZ837260
- Authority / Receiving Office
- NZ · NZ
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2020-11-05
- Filing Date
- 2021-09-21
- Publication Date
- 2026-09-25
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Figure 1_ABST
Abstract
A bispecific tetravalent antibody having a binding specificity to a human epithelium growth factor receptor (EGFR), comprising, from N terminus to C terminus, a Fab region having a first binding specificity to human EGFR, wherein the Fab region comprises a variable region having an amino acid sequence having at least 90% of sequence identity to the sequences as disclosed herein; a Fc domain, and a scFv domain having a second binding specificity to HER3.
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