Triple agonists of the GLP1 / GIP / NPY2 receptors

PA95460A1Pending Publication Date: 2026-09-09BOEHRINGER INGELHEIM INT GMBH
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Patent Information

Application Number
PA95460
Authority / Receiving Office
PA · PA
Patent Type
Applications
Current Assignee / Owner
Filing Date
2025-05-30
Publication Date
2026-09-09
Patent Text Reader

Abstract

Hybrid polypeptides that are agonists of the GIP, GLP-1, and neuropeptide Y2 (NPY2) receptors and their medical use in the treatment of a variety of diseases, conditions, or disorders, such as obesity, diabetes, and / or NASH. The polypeptides have the general structure Z1-Z2-Z3, where Z1 is a hybrid polypeptide that agonistizes both GIPR and GLP1R, Z2 is a linker, and Z3 is a polypeptide that agonistizes HY2R.
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