Polyq inhibitors

Abstract

The specification relates generally to compounds of formula (I): (I), or a pharmaceutically acceptable stereoisomer or salt thereof, wherein G, GA1, GB1, X, Y, R1, R2, Q1, Q2, and Q3 have any of the meanings defined herein, together with compositions containing them and their use in therapy. The compounds are inhibitors of the polymerase, DNA polymerase theta (POL0 or POLQ), and are therefore particularly useful in the treatment of cancer.