Therapeutic CD47 antibodies

PH12018500515B1Undetermined Publication Date: 2023-08-31ARCH ONCOLOGY INC

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Patent Information

Application Number: PH12018500515
Authority / Receiving Office: PH · PH
Patent Type: Patents
Current Assignee / Owner
Priority Date: 2016-06-24
Filing Date: 2016-09-17
Publication Date: 2023-08-31
Estimated Expiration: 2036-09-17

Application Information

Patent Timeline

24 Jun 2016

Priority

17 Sep 2016

Application

PH12018500515

31 Aug 2023

Publication

PH12018500515B1

IPC: A61K; C07K

Inventors: MANNING, PAMELA; KARR, ROBERT, W.

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Abstract

Provided are anti-CD47 monoclonal antibodies (anti-CD47 mAbs) with distinct functional profiles as described herein, methods to generate anti-CD47 mAbs, and to methods of using these anti-CD47 mAbs as therapeutics for the prevention and treatment of solid and hematological cancers, ischemia-reperfusion injury, cardiovascular diseases, autoimmune diseases, inflammatory diseases or as diagnostics for determining the level of CD47 in tissue samples.

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