Compounds for treatment of alzheimer`s disease

Abstract

The invention relates to certain chromanol, quinone or hydroquinone compounds and derivatives thereof for treatment of Alzheimer's disease and / or for improving memory function and / or reducing plaque load. Specifically, the present invention relates to chromanol compounds chosen from (6-hydroxy-2,5,7,8tetramethylchroman-2yl)(piperazin-1-5 yl)methanone, ((S)-6-hydroxy-2,5,7,8tetramethyl-N-((R)-piperidin-3-yl)chroman-2- carboxamide hydrochloride and S-(6hydroxy-2,5,7,8-tetramethylchroman-2-yl)(4-(2- hydroxyethyl)piperazin-1- yl)methanone, and pharmaceutically acceptable salts thereof.