Stable antibody formulation

PH12022551721B1Active Publication Date: 2026-10-02REGENERON PHARMACEUTICALS INC
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Patent Information

Application Number
PH12022551721
Authority / Receiving Office
PH · PH
Patent Type
Patents
Current Assignee / Owner
Filing Date
2022-07-11
Publication Date
2026-10-02
Estimated Expiration
2042-07-11
Patent Text Reader

Abstract

The present disclosure provides stable pharmaceutical formulations comprising a human antibody that specifically binds to Ebola Virus (EBOV). In certain embodiments, the formulations contain, in addition to an anti-EBOV antibody, a buffer, an amino acid, a non ionic surfactant, and a stabilizer. The pharmaceutical formulations of the present disclosure exhibit a substantial degree of antibody stability upon stress, for example, agitation during transport, and storage, for example, storage at temperatures greater than 40°C.
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