A method for the preparation of a pharmaceutical composition comprising 5-[7 ]2-(5-methyl-2-phenyl-oxazole-4-yl) benzothiophene-4-methyl]-2,4 thiazolidinedione

Abstract

The present invention relates to a method for the preparation of composition, preferably pharmaceutical composition, in form of expanded, mechanically stable, lamellar, porous, spongue-like or foam structures out of solutions and dispersions. The method comprises the steps of a ) preparing a solution or a homogeneous dispersion of a liquid and a compound selected from the group consisting of one or more pharmaceutically active compound, one or more pharmaceutically suitable excipients, and mixture thereof, followed by b) the expansion of the solution or the homogeneous dispersion without boiling. The invention also relates to the composition, its further processing and any corresponding dosage forms obtainable by the above method.