Polymorphic form of 1-[4-(5-cyanoindol-3 yl))butyl]-4-(2-carbamoylbenzofuran-5 yl)piperazine hydrochloride

Abstract

The invention relates to new crystalline modifications of the hydrochloride of 1-[4-(5 cyanoindol-3-yl)butyl]-4-(2-carbamoyI benzofuran-5-yl)-piperazine, crystalline modification of the dihydrochloride of 1-[4-(5 cyanoindol-3-yl)butyl]-4-(2-carbamoyl benzofuran-5-yI)- piperazine and amorphous 1 [4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl benzofuran-5-yl)-piperazine hydrochloride which are suitable in particular for the preparation of solid medicaments for the treatment or prevention of depressive disorders, anxiety disorders, bipolar disorders, mania, dementia, substance-related disorders, sexual dysfunctions, eating disorders, obesity, fibromyalgia, sleeping disorders, psychiatric disorders, cerebral infarct, tension, for the therapy of side-effects in the treatment of hypertension, cerebral disorders, chronic pain, acromegaly, hypogonadism, secondary amenorrhea, premenstrual syndrome and undesired puerperal lactation.