Substituted n-(heteroary)-1h-indole-2-carboxamide compound.

Abstract

The invention relates to a compound of general formula (I): in which n is equal to 0, 1, 2 or 3: X1, X2, X3, X4, Z1, Z2, Z3, Z4 and Z5 represent, independently of each other, a hydrogen or halogen atom or a C1-C5-alkyl, C3-C7-cycloalkyl, C3-C7-cycloalkyl-C1-C3-alkylene, C1-C5-fluoroalkyl, C1-C6-alkoxy, C1-C5-fluoroalkoxy, cyano, C(O)NR1R2, nitro, NR1R2, C1-C5-thioalkyl, -S(O)-C1-C6-alkyl, S(O)2¬C1-C6-alkyl, -SO2NR1R2, NR3COR4, NR3SO2R5 or aryl group, the aryl being optionally substituted; W represents a fused bicyclic group of formula: linked to the nitrogen atom via positions 1, 2, 3 or 4; A represents an optionally substituted 5- to 7-membered heterocycle comprising from one to three heteroatoms chosen from O, S and N; in the form of base or of acid-addition salt, and also in the form of hydrate or solvate. Preparation process and therapeutic application.