A somatostatin peptide and a pharmaceutical composition comprising thereof.

Abstract

Somatostatin hexapeptide comprising the amino acid sequence of the formula (I): - (D / L)Trp-Lys-X1-X2, wherein X1 is a substituted Thr, Ser, Tyr, Glu or Cys residue and X2 is an alpha -amino acid having an aromatic residue on the C alpha side chain, or an amino acid unit selected from Dab, Dpr, Dpm, His (BzI)HyPro, thienyl-Ala, cyclohexyl- Ala and t-butyl-Ala, the residue Lys of said sequence corresponding to the residue Lys<9> of the native somatostatin-14 have interesting pharmacological properties.