A salt or complex form of a somatostatin peptide.

PK140648AUndetermined Publication Date: 2010-04-21NOVARTIS AG
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Patent Information

Application Number
PK200700844
Authority / Receiving Office
PK · PK
Patent Type
Applications
Current Assignee / Owner
Publication Date
2010-04-21
Patent Text Reader

Abstract

A complex of a somatostatin hexapeptide comprising the amino acid sequence of the formula (I): -(D / L)Trp-Lys-X1-X2, wherein X1 is a substituted Thr, Ser, Tyr, Glu or Cys residue and X2 is an alpha-amino acid having an aromatic residue on the C alpha side chain, or an amino acid unit selected from Dab, Dpr, Dpm, His (Bzl)HyPro, thienyl--Ala, cyclohexyl-Ala and t-butyl-Ala, the residue Lys of said sequence corresponding to the residue Lys<9> of the native somatostatin-14 have interesting pharmacological properties.
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