A new tiotropium iodide salt and pharmaceutical composition comprising thereof

Abstract

The invention relates to a new tiotropium salts of formula 1 wherein X- denotes an anion, selected from the group consisting of - crystalline tiotropium chloride, which is characterised in that in the X-ray powder diagram it has the characteristic values d= 6.15 A; 5.58 A; 4.45 A and 3.93 A, inter alia and - crystalline tiotropium iodide, which is characterised in that in the X-ray powder diagram it has the characteristic values d= 6.30 A; 5.19 A; 4.47 A; 4.11 A and 3.55 A, inter alia, and pharmaceutical formulation containing them and their use for the treatment of respiratory complaints, particularly for the treatment of COPD (chronic obstructive pulmonary disease) and asthma.