1H-thieno[2,3-c]pyrazole useful as kinase inhibitors

PK140710AUndetermined Publication Date: 2010-05-17PHARMACIA ITAL SPA
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Patent Information

Application Number
PK200500064
Authority / Receiving Office
PK · PK
Patent Type
Applications
Current Assignee / Owner
Publication Date
2010-05-17
Patent Text Reader

Abstract

A compound of formula (I) Wherein R is an optionally substituted aryl or heteroaryl group; R1 and R2 represent, the same or different and independently from each other, a hydrogen atom, a straight or branched C1-C3 alkyl or a group –CONH2 or –CH2NR’R” or, taken together with the carbon atom to which they are bonded, R1 and R2 may from a C3-C6 cycloalkyl group; with the proviso that at least one of R1 and R2 is other than a hydrogen atom; R’ and R” represent, the same or different and independently from each other, a hydrogen atom or straight or a branched C1-C3 alkyl group or, taken together with the nitrogen atom to which they are bonded, R’ and R” may form a heterocyclic ring of formulaWherein R” is a hydrogen atom or a straight or branched C1-C3 alkyl group; R3 is a hydrogen or halogen atom or a group selected from hydroxyl, cyano, straight or branched C1-C3 alkyl or C1-C3 alkoxy; use for treating cell proliferactive disorders caused by and / or with an altered protein kinase activity.
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