A therapeutic antibody, method for its preparation and Pharmaceutical composition comprising thereof

Abstract

The present invention concerns immunoglobulins, particularly antibodies which specifically bind human Interleukin 13 (hIL-13). Antibodies of the invention may be used in the treatment of a variety of diseases or disorders responsive to modulation of the interaction between hIL-13 and the human IL- 13 receptor. Such diseases include severe asthma, atopic dermatitis, COPD and various fibrotic diseases. Pharmaceutical composition comprising said antibodies and methods of manufacture are also disclosed.