An n-(substituted glycyl)-2 cyanopyrrolidine compound
PK141042AUndetermined Publication Date: 2010-12-30NOVARTIS AG
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Patent Information
- Application Number
- PK199901054
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Publication Date
- 2010-12-30
Abstract
The present invention relates to a compound of formula (I) wherein R is substituted adamantyl; and n is 0 to 3; in free form or in acid addition salt form. Compounds of formula I inhibit DPP IV (dipeptidyl-peptidase-IV) activity. They are therefore indicated for use as pharmaceutical in inhibiting DPP-IV and in the treatment of conditions mediated by DPP-IV, such as non-insulin-dependent diabetes mellitus, arthritis, obesity, osteoporosis and further conditions of impaired glucose tolerance.
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