New process for the resolution of enantiomers of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)nitrile and application in the synthesis of ivabradineV
PK200900756A0Undetermined Publication Date: 2009-08-21LES LAB SERVIER SA
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Patent Information
- Application Number
- PK200900756
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2009-08-10
- Publication Date
- 2009-08-21
Abstract
Process for the optical resolution of the compound of formula (I): by chiral chromatography. Application in the synthesis of ivabradine, of its addition salts with a pharmaceutically acceptable acid and of their hydrates.
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