Novel imidazolidine compounds as androgen receptor modulators

Abstract

Novel compounds are disclosed that have a Formula represented by the following: wherein X, R1, R20, R2b, R2c, R3a, R3b, R4s, R4b, R4c and ml areas described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, cachexia, osteoporosis, sarcopenia, a decline in libido and / or sexual dysfunction.