C-met therapeutic antibodies

PK200901028A0Undetermined Publication Date: 2009-12-18ELI LILLY & CO
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Patent Information

Application Number
PK200901028
Authority / Receiving Office
PK · PK
Patent Type
Applications
Current Assignee / Owner
Filing Date
2009-11-23
Publication Date
2009-12-18
Patent Text Reader

Abstract

Provided herein is a monoclonal antibody, antigen-binding fragment thereof, and combinations of the foregoing, that binds to, and inhibits the activity of, c-Met, and induces hepatocyte-growth factor-independent internalization of cell surface human c- Met. The monoclonal antibody or antigen-binding fragment thereof is effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by c- Met.
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