N-phenyl-(piperazinyl or homopiperazinyl)-benzene sulfonamide or benzenesulfonyl phenyl-(piperazine or homopiperazine) compounds suitable for treating disorders that respond to modulation of the serotonin 5-ht(beta) receptor

Abstract

The present invention relates to an N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compound, pharmaceutical composition containing it. The compound possesses valuable therapeutic properties and is particularly suitable for treating diseases that respond to modulation of the serotonin 5-HT6 receptor. whereinX is a bond or a group N-R4;R1 is hydrogen or methyl;R2 is hydrogen or methyl;R3 is hydrogen, C1-C3 alkyl, fluorine, C1-C2 alkoxy or fluorinated C1-C2 alkoxy;R4 is hydrogen, C1-C4 alkyl, C3-C4 cycloalkyl, or C3-C4 cycloalkyl-CH2-;R5 is hydrogen, fluorine, chlorine, C1-C2 alkyl, fluorinated C1-C2 alkyl, C1-C2 alkoxy or fluorinated C1-C2 alkoxy;R6 is hydrogen, fluorine or chlorine; andn is 1 or 2.