Insecticidal compounds based on isoxazoline derivatives

Abstract

The present invention relates to compound of formula (I): wherein A 1, A2, A3 and A4 are independently of one another C-H, C-R5, or nitrogen; G1 is oxygen or sulfur; L is a single bond or Cj-Cgalkylene; R1 is hydrogen, Ci-Cgalkyl, Ci-Cgalkyl carbonyl-, Cj-Cgalkoxy, Ci-Cgalkoxy-Cj-Cgalkyl or CiCgalkoxycarbonyl-; R2 is hydrogen, Ci-Cghaloalkyl or Ci-Cgalkyl; R3 is Ci-Cghaloalkyl; R4 is aryl or aryl substituted by one to three Rb, or R4 is heterocyclyl or heterocyclyl substituted by one to three R6; each R5 is independently halogen, cyano, nitro, Ci-Cgalkyl, C3-Cgcycloalkyl, Ci-Cghaloalkyl, C2“Cgalkenyl, C2-Cghaloalkenyl, C2-Cgalkynyl, C2Cghaloalkynyl, Ci-Cgalkoxy, Ci-Cghaloalkoxy, Ci-Cgalkoxycnrbonyl-, or two R5 on adjacent carbon atoms together form a -CH=CH-CH=CHbridge or a -N=CH-CH=CH- bridge; each R6 is independently halogen, cyano, nitro, Ci-Cgalkyl, Ci-Cghaloalkyl, Ci-Cgalkoxy, or CiCghaloalkoxy; Y 1 is CR7R8, Y2 is 0 , Y3 is N-R9 and Y4 is C=0; each R7 and R8 is independently hydrogen, halogen, Ci-Cgalkyl, or Ci-Cghaloalkyl; each R9 is independently hydrogen, cyano, cyanoCi-C8alkyl, Ci-C8alkyl,Ci-C8haloalkyl, C3Cgcycloalkyl, C3-Cgcycloalkyl where one carbon atom is replaced by 0 , S, S(O) or SO2, or C3Cgcycloalkyl-C 1 -Cgalkyl, C3-Cgcycloalkyl-C 1 Cgalkyl where one carbon atom in the cycloalkyl group is replaced by 0 , S, S(O) or SO2, or C3Cgcycloalkyl-Ci-Cghaloalkyl, Ci-Cghydroxyalkyl, Ci-C8alkoxy-Ci-Cgalkyl,C2-Cgalkenyl, C2Cghaloalkenyl, C2 -Cgalkynyl, C2-C8haloalkynyl, phenyl, phenyl substituted by one to three R10, phenyl-Ci-C4alkyl, phenyl-Ci-C4alkyl wherein the phenyl moiety is substituted by one to three R10, 5-6 membered heteroaryl-Ci-C4alkyI or 5-6 membered heteroaryl-Ci-C4 alkyl wherein the heteroaryl moiety is substituted by one to three R10, Ci-C4alkyl-(Ci-C4alkyl-0-N=)C-CH2-; each R10 is independently halogen, cyano, nitro, CiCgalkyl, Ci-Cghaloalkyl, Ci-Cgalkoxy, or C r C8haloalkoxy. Furthermore, the present invention relates to intermediates for preparing compound of formula (I), to composition comprising it and to method of using the same to combat and control insect, acarine, nematode and mollusc pests.