Substituted isoquinolinones and quinazolinones
PK201001057A0Undetermined Publication Date: 2011-01-08NOVARTIS AG
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Patent Information
- Application Number
- PK201001057
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2010-12-20
- Publication Date
- 2011-01-08
Abstract
The invention relates to substituted nitrogen containing bicyclic heterocycle of the formula (I)wherein Z is CH2 or N-R 4 and X, R1 , R2 , R4 , R6 , R 7 and n are as defined in the description. Said compound is suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and / or MDM4, or variants thereof
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