Pyrazine derivatives as enac blockers

PK201100674A0Active Publication Date: 2011-09-24NOVARTIS AG
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Patent Information

Authority / Receiving Office
PK · PK
Patent Type
Applications
Current Assignee / Owner
NOVARTIS AG
Filing Date
2011-09-15
Publication Date
2011-09-24
Patent Text Reader

Abstract

Compound of Formula I: and pharmaceutically acceptable solvates thereof, wherein R1 , R2 , R3 , R4 , R5 , R6 , R7 , R8 , R9 , and R10 have the meanings as indicated in the specification, is useful for treating diseases mediated by blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compound and processes for preparing the compound are also described.
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