Antigen binding proteins

PK201200330A0Active Publication Date: 2012-06-20GLAXO GROUP LTD
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Patent Information

Authority / Receiving Office
PK · PK
Patent Type
Applications
Current Assignee / Owner
GLAXO GROUP LTD
Filing Date
2012-05-25
Publication Date
2012-06-20
Patent Text Reader

Abstract

The invention relates to antigen binding protein and fragment thereof and provides an antigen binding protein which specifically binds B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and / or APRIL to BCMA receptor. The invention further provides an immunoconjugate and pharmaceutical composition comprising the antigen binding protein for use in the treatment of B cell lymphoma such as Multiple Myeloma (MM) or chronic Lymphocytic Leukaemia (CLL).
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