Method for producing titanium material modified with a layer of titanium phosphate doped with bioactive ions for use as an orthopedic implant

Abstract

The subject of the application is a method for producing a titanium material modified with a titanium phosphate layer doped with bioactive ions for use as an orthopedic or dental implant, characterized in that the ground and cleaned titanium material is placed in a hydrothermal reactor containing a mixture of hydrogen peroxide (H2O2) and phosphoric acid (H3PO4) for 24 hours at an elevated temperature, preferably 120°C, then the titanium material prepared in this way is subjected to ion sorption by immersing it in a 0.1 M solution of magnesium chloride (MgCl2), calcium chloride (CaCl2) or strontium chloride (SrCl2) for 24 hours at an elevated temperature, preferably 100°C, then it is washed in deionized water, preferably three times, with each rinsing step lasting 10 minutes, after which the titanium material with the produced titanium phosphate layer doped with bioactive calcium, magnesium or strontium ions is washedthey are dried for 24 hours at 50°C and placed in ciprofloxacin solution for 7 days at 25°C,