Peptide hydrogels used for dental enamel remineralization and regeneration

Abstract

The invention relates to a composition of bioactive hydrogel with leucine-rich amelogenin peptide, meant to be used for dental enamel remineralization and regeneration. According to the invention, the hydrogel composition is a mixture of biocompatible polymers (PEG 600), peptides and nanofillers of crystallized hydroxyapatite and SiO2, where the biocompatible polymer is polyethylene glycol - PEG 600 - 23⋯27%, SiO2 5⋯8%, distilled water 55⋯57%, powder of hydroxyapatite (HA) crystallized at 700°C 5⋯9% and 1% 2-hydroxyethyl salicylate and / or 40...60 μl Anti - Amelogenin, Xisoform, ABT260 and / or 40...60 μl Anti - Kallikrein L1, K3014.