NEW HETEROCYCLIC COMPOUNDS

RU2024124385A3Pending Publication Date: 2026-06-30F HOFFMANN LA ROCHE & CO AG
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Patent Information

Authority / Receiving Office
RU · RU
Patent Type
Applications
Current Assignee / Owner
F HOFFMANN LA ROCHE & CO AG
Filing Date
2023-01-25
Publication Date
2026-06-30
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Claims

1. Compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein: A is selected from: B is selected from C6-C 14 -aryl, C3-C 10 -cycloalkyl, 5-14-membered heteroaryl and 3-14-membered heterocyclyl; C is selected from C6-C 14 -aryl, C3-C 10 -cycloalkyl, 3-14-membered heterocyclyl and 5-14-membered heteroaryl; L 1 selected from covalent bond, carbonyl, -CR 8a R 8b -, -CH2O-, -ОСН2-, -CH2NR 13a -, -NR 13b CH2-, -CH2CH2-, -CH2NR 13c CH2-, -CH2NHCO-, -О-, -NH-, -SQ2NH-, -NHSO2-, -SO2NHCH2-, -CH2NHSO2-, -SO2-, -CH2SO2-, -SO2CH2-, -NHC(O)-, -C(O)NH- and L 2 selected from the covalent bond, -CR 8a R 8b-, -NH-, -N(C1-C6-alkyl)-, -O-, -CH2NH-, -NHCH2-, -CH2O-, -OCH2-, -SO2-, -CH2SO2- and -SO2CH2-; X represents NH or O; R 1 selected from the group C1-C6-alkyl-SO2-NH-, C1-C6-alkyl-SO2- and halogen-C1-C6-alkyl-C(O)-; R 2 selected from hydrogen and hydroxy; R 3 selected from hydrogen, halogen, cyano, C1-C6 alkyl, C1-C6 alkoxy and hydroxy; R 4 selected from hydrogen and the -C(R group 4a R 4b R 4c ); R 4a selected from C1-C6 alkyl and halo-C1-C6 alkyl; R 4b selected from hydrogen and hydroxy; and R 4c is hydrogen; or each of R 4a , R 4b and R 4c independently selected from hydrogen and halogen; or R 4a and R 4b , taken together with the carbon atom to which they are attached, form C3-C 10 -cycloalkyl or 3-14 membered heterocyclyl; and R 4cselected from hydrogen, hydroxy, amino and halogen; and specified C3-C 10 -cycloalkyl and 3-14-membered heterocyclyl optionally substituted with 1-2 halogen substituents; R 5 selected from hydrogen, hydroxy, halogen, cyano, C1-C6-alkyl, C1-C6-alkoxy, halo-C1-C6-alkyl, hydroxy-C1-C6-alkyl, hydroxyhalo-C1-C6-alkyl, carboxy-C1-C6-alkyl, halo-C1-C6-alkoxy, oxo, NH2-SO2-, amino, C1-C6-alkyl-NH-, (C1-C6-alkyl)2N-, carbamoyl, C1-C6-alkyl-NH-C(O)-, (C1-C6-alkyl)2N-C(O)-, carboxy, C1-C6-alkoxycarbonyl, C1-C6-alkoxycarbonyl-C1-C6-alkyl-, (C1-C6-alkyl)2P(O)-, (C1-C6-alkyl)2P(O)-C1-C6-alkyl-, group and groups R 6 selected from hydrogen, halogen, cyano, oxo, C1-C6-alkyl, halo-C1-C6-alkyl, halogen-C1-C6-alkyl and C1-C6-alkyl-SO2-; R 7 selected from hydrogen and C1-C6-alkyl; R 8a selected from hydrogen, halogen, C1-C6-alkyl and carbamoyl; R 8bselected from hydrogen and halogen; R 9 selected from hydrogen, halogen, cyano, hydroxy, oxo, carboxy, C1-C6-alkoxycarbonyl, amino, C1-C6-alkyl-NH-, (C1-C6-alkyl)2N-, carbamoyl, C1-C6-alkyl-NH-C(O)-, C1-C6-alkyl, hydroxy-C1-C6-alkyl, halo-C1-C6-alkyl, C1-C6-alkoxy-C1-C6-alkyl, C1-C1-alkoxy, halo-C1-C6-alkoxy, C3-C 10 -cycloalkyl, cyano, C1-C6-alkyl-SO2-, halogen-C1-C6-alkyl-SO2- and 5-14-membered heteroaryl; wherein said C3-C 10 -cycloalkyl and 5-14-membered heteroaryl are optionally substituted with one substituent selected from C1-C8 alkyl and halo-C1-C6 alkyl; or R 9 and R 5 together they form a group ; R 10 selected from hydrogen, halogen, C1-C6-alkyl, halo-C1-C6-alkyl and R 11 selected from hydrogen and halogen; R 12 selected from amino, C1-C6 alkyl and halo-C1-C6 alkyl; and each of R 13a , R 13b and R 13cindependently selected from hydrogen, C1-C6 alkyl, C3-C 10 -cycloalkyl, C3-C 10 -cycloalkyl-C1-C6-alkyl-.

2. A compound of formula (I) according to claim 1 or a pharmaceutically acceptable salt thereof, wherein A is selected from:

3. A compound of formula (I) according to claim 2 or a pharmaceutically acceptable salt thereof, wherein A is selected from:

4. A compound of formula (I) according to any one of claims 1 to 3 or a pharmaceutically acceptable salt thereof, wherein: B is selected from C6-C 14 -aryl, C3-C 10 -cycloalkyl, 5-14-membered heteroaryl and 3-14-membered heterocyclyl; C is selected from C6-C 14 -aryl, C3-C 10 -cycloalkyl, 3-14-membered heterocyclyl and 5-14-membered heteroaryl; L 1 selected from covalent bond, carbonyl, -CR 8a R 8b -,-CH2O-, -ОСН2-,-CH2NR 13a -, -NR 13b CH2-, -CH2CH2-, -CH2NR 13cCH2-, -CH2NHCO-, -О-, -NH-, -SO2NH-, -NHSO2-, -SO2NHCH2-, -CH2NHSO2-, -SO2-, -NHC(O)-, -C(O)NH- and L 2 selected from the covalent bond, -CR 8a R 8b -, -NH-, -N(C1-C6-alkyl)-, -O-, -CH2NH-, -NHCH2-, -CH2O-, -OCH2-, -SO2- and -CH2SO2-; X represents NH or O; R 1 selected from the group C1-C6-alkyl-SO2-NH-, C1-C6-alkyl-SO2- and halogen-C1-C6-alkyl-C(O)-; R 2 selected from hydrogen and hydroxy; R 5 selected from hydrogen, hydroxy, halogen, cyano, C1-C6 alkyl, C1-C6 alkoxy, halogen-C1-C6 alkyl, hydroxy-C1-C6 alkyl, hydroxyhalogen-C1-C6 alkyl, carboxy-C1-C6 alkyl, halogen-C1-C6 alkoxy, oxo, NH2-SO2-, C1-C6-alkyl-NH-, carbamoyl, C1-C6-alkyl-NH-C(O)-, carboxy, C1-C6-alkoxycarbonyl, C1-C6-alkoxycarbonyl-C1-C6-alkyl-, (C1-C6-alkyl)2P(O)-, (C1-C6-alkyl)2P(O)-C1-C6-alkyl-, groups and groups R 6selected from hydrogen, halogen, cyano, oxo, C1-C6-alkoxy, halo-C1-C6-alkoxy, halo-C1-C6-alkyl and C1-C6-alkyl-SO2-; R 7 selected from hydrogen and C1-C6 alkyl; R 8a selected from hydrogen, halogen, C1-C6 alkyl and carbamoyl; R 8b selected from hydrogen and halogen; R 9 selected from hydrogen, halogen, cyano, hydroxy, oxo, carboxy, C1-C6 alkoxycarbonyl, C1-C6 alkyl-NH-, carbamoyl, C1-C6 alkyl-NH-C(O)-, C1-C6 alkyl, hydroxy-C1-C6 alkyl, halogen-C1-C6 alkyl, C1-C6-alkoxy-C1-C6-alkyl, C1-C6-alkoxy, halogen-C1-C6-alkoxy, C3-C 10 -cycloalkyl, cyano, C1-C6-alkyl-SO2-, halogen-C1-C6-alkyl-SO2- and 5-14-membered heteroaryl; wherein said C3-C 10 -cycloalkyl and 5-14-membered heteroaryl are optionally substituted with one substituent selected from C1-C6-alkyl and halo-C1-C6-alkyl; or R 9 and R 5 together they form a group ; R 10selected from hydrogen, halogen, C1-C6-alkyl, halo-C1-C6-alkyl and oxo; R 11 selected from hydrogen and halogen; R 12 selected from amino, C1-C6-alkyl and halo-C1-C6-alkyl; R 13a selected from hydrogen, C1-C6 alkyl, C3-C 10 -cycloalkyl, C3-C 10 -cycloalkyl-C1-C 10 -alkyl-; R 13b is hydrogen; and R 13c selected from hydrogen and C1-C6 alkyl.

5. A compound of formula (I) according to claim 4 or a pharmaceutically acceptable salt thereof, wherein: B is selected from C6-C 14 -aryl, C3-C 10 -cycloalkyl, 5-14-membered heteroaryl and 3-14-membered heterocyclyl; C is selected from C3-C 10 -cycloalkyl and 5-14 membered heteroaryl; L 1 selected from the covalent bond, -CR 8a R 8b - and -CH2O-; L 2 selected from the covalent bond, -NH- and -CH2NH-; X represents NH or O; R 1 is a group R 2 represents hydrogen; R 5 selected from halogen, cyano, halo-C1-C6-alkyl, oxo, halo-C1-C6-alkoxy, C1-C6-alkyl-SO2-, halo-C1-C6-alkyl-SO2-, group and groups R 6 selected from hydrogen, halogen, cyano and halogen-C1-C6-alkyl; R 7 selected from hydrogen and C1-C6 alkyl; R 8a selected from hydrogen and halogen; R 8b selected from hydrogen and halogen; R 9 selected from hydrogen, C1-C6 alkyl and halo-C1-C6 alkyl; R 10 selected from hydrogen, C1-C6 alkyl and halo-C1-C6 alkyl; R 11 is hydrogen; and R 12 is a halogen-C1-C6-alkyl.

6. A compound of formula (I) according to claim 5 or a pharmaceutically acceptable salt thereof, wherein: B is selected from phenyl, bicyclo[1.1.1]pentyl, pyridyl, oxazolyl, pyrimidinyl, pyrazinyl, pyridazinyl, 1,2,4-thiadiazolyl, pyrazolyl, imidazolyl, 1H-1,2,4-triazolyl, triazol-2-yl, 2H-triazolyl, isoxazolyl, 1,2,4-oxadiazolyl, 1,3,4-oxadiazolyl, 1,2-dihydropyridyl and 1,2-dihydropyrazinyl; C is selected from cyclopropyl, pyrazolyl, 1,3,4-oxadiazolyl, 1,3,4-thiadiazolyl and pyrazinyl; L 1 selected from the covalent bond, -CR 8a R 8b - and -CH2O-; L 2 selected from the covalent bond, -NH- and -CH2NH-; X represents NH or O; R 1 is a group R 2 represents hydrogen; R 5 selected from chlorine, fluorine, cyano, CF3, 2,2,2-trifluoroethyl, CF3O, oxo, methylsulfonyl, CF3-SO2-, group and groups R 6 selected from hydrogen, fluorine, cyano and CF3; R 7selected from hydrogen and methyl; R 8a selected from hydrogen and fluorine; R 8b selected from hydrogen and fluorine; R 9 selected from hydrogen, methyl, 2,2-dimethylpropyl, CHF2 and CF3; R 10 selected from hydrogen, methyl and CF3; R 11 is hydrogen; and R 12 represents CF3.

7. A compound of formula (I) according to any one of claims 1 to 6 or a pharmaceutically acceptable salt thereof, where R 3 is hydrogen.

8. A compound of formula (I) according to any one of claims 1 to 7 or a pharmaceutically acceptable salt thereof, wherein: R 4 represents the group -C(R 4a R 4b R 4c ); Where each of R 4a , R 4b and R 4c independently represents a halogen; or R 4a and R 4b , taken together with the carbon atom to which they are attached, form C3-C 10-cycloalkyl; and R 4c selected from hydrogen, hydroxy and halogen; wherein said C3-C 10 -cycloalkyl is optionally substituted with 1-2 halogen substituents.

9. A compound of formula (I) according to claim 8 or a pharmaceutically acceptable salt thereof, wherein: R 4 represents the group -C(R 4a R 4b R 4c ); Where each of R 4a , R 4b and R 4c independently represents fluorine; or R 4a and R 4b , taken together with the carbon atom to which they are attached, form cyclopropyl or cyclobutyl; and R 4c selected from hydrogen, hydroxy and fluoro; wherein said cyclopropyl is optionally substituted with 1-2 fluoro substituents.

10. A compound of formula (I) according to claim 1 or a pharmaceutically acceptable salt thereof, wherein: A is selected from: B is selected from C6-C 14 -aryl, C3-C 10-cycloalkyl, 5-14-membered heteroaryl and 3-14-membered heterocyclyl; C is selected from C6-C 14 -aryl, C3-C 10 -cycloalkyl, 3-14-membered heterocyclyl and 5-14-membered heteroaryl; L 1 selected from covalent bond, carbonyl, -CR 8a R 8b -, -CH2O-, -OCH2-, -CH2NR 13a -, -NR 13b CH2-, -CH2CH2-, -CH2NR 13c CH2-, -CH2NHCO-, -O-, -NH-, -SO2NH-, -NHSO2-, -SO2NHCH2-, -CH2NHSO2-, -SO2-, -NHC(O)-, -C(O)NH- and L 2 selected from the covalent bond, -CR 8a R 8b -, -NH-, -N(C1-C6-alkyl)-, -O-, -CH2NH-, -NHCH2-, -CH2O-, -OCH2-, -SO2- and -CH2SO2-; X represents NH or O; R 1 selected from the group C1-C6-alkyl-SO2-NH-, C1-C6-alkyl-SO2- and halogen-C1-C6-alkyl-C(O)-; R 2 selected from hydrogen and hydroxy; R 3 represents hydrogen; R 4selected from hydrogen and the -C(R group 4a R 4b R 4c ); R 4a is a halogen-C1-C6-alkyl; R 4b is hydroxy; and R 4c is hydrogen; or each of R 4a , R 4b and R 4c independently represents a halogen; or R 4a and R 4b , taken together with the carbon atom to which they are attached, form C3-C 10 -cycloalkyl or 3-14 membered heterocyclyl; and R 4c selected from hydrogen, hydroxy, amino and halogen; wherein said C3-C 10 -cycloalkyl and 3-14-membered heterocyclyl are optionally substituted with 1-2 halogen substituents; R 5selected from hydrogen, hydroxy, halogen, cyano, C1-C6-alkyl, C1-C6-alkoxy, halo-C1-C6-alkyl, hydroxy-C1-C6-alkyl, hydroxyhalo-C1-C6-alkyl, carboxy-C1-C6-alkyl, halo-C1-C6-alkoxy, oxo, NH2-SO2-, C1-C6-alkyl-NH-, carbamoyl, C1-C6-alkyl-NH-C(O)-, carboxy, C1-C6-alkoxycarbonyl, C1-C6-alkoxycarbonyl-C1-C6-alkyl-, (C1-C6-alkyl)2P(O)-, (C1-C6-alkyl)2P(O)-C1-C6-alkyl-, group and groups R 6 selected from hydrogen, halogen, cyano, oxo, C1-C6-alkoxy, halo-C1-C6-alkoxy, halo-C1-C6-alkyl and C1-C6-alkyl-SO2-; R 7 selected from hydrogen and C1-C6-alkyl; R 8a selected from hydrogen, halogen, C1-C6-alkyl and carbamoyl; R 8b selected from hydrogen and halogen; R 9selected from hydrogen, halogen, cyano, hydroxy, oxo, carboxy, C1-C6-alkoxycarbonyl, C1-C6-alkyl-NH-, carbamoyl, C1-C6-alkyl-NH-C(O)-, C1-C6-alkyl, hydroxy-C1-C6-alkyl, halogen-C1-C6-alkyl, C1-C6-alkoxy-C1-C6-alkyl, C1-C6-alkoxy, halogen-C1-C6-alkoxy, C3-C 10 -cycloalkyl, cyano, C1-C6-alkyl-SO2-, halogen-C1-C6-alkyl-SO2- and 5-14-membered heteroaryl; wherein said C3-C 10 -cycloalkyl and 5-14-membered heteroaryl are optionally substituted with one substituent selected from C1-C6-alkyl and halo-C1-C6-alkyl; or R 9 and R 5 together they form a group ; R 10 selected from hydrogen, halogen, C1-C6 alkyl, halo-C1-C6 alkyl and oxo; R 11 selected from hydrogen and halogen; R 12 selected from amino, C1-C6-alkyl and halo-C1-C6-alkyl; R 13a selected from hydrogen, C1-C6 alkyl, C3-C 10 -cycloalkyl, C3-C 10 -cycloalkyl-C1-C6-alkyl-; R 13b is hydrogen; and R 13c selected from hydrogen and C1-C6 alkyl.

11. A compound of formula (I) according to claim 10 or a pharmaceutically acceptable salt thereof, wherein: A is selected from: B is selected from C6-C 14 -aryl, C3-C 10 -cycloalkyl, 5-14-membered heteroaryl and 3-14-membered heterocyclyl; C is selected from C3-C 10 -cycloalkyl and 5-14 membered heteroaryl; L 1 selected from the covalent bond, -CR 8a R 8b - and -CH2O-; L 2 selected from the covalent bond, -NH- and -CH2NH-; X represents NH or O; R 1 is a group R 2 represents hydrogen; R 3 represents hydrogen; R 4 represents the group -C(R 4a R 4b R 4c ); each of R 4a , R 4b and R 4c independently represents a halogen; or R 4a and R 4b , taken together with the carbon atom to which they are attached, form C3-C 10 -cycloalkyl; and R 4c selected from hydrogen, hydroxy and halogen; wherein said C3-C 10 -cycloalkyl is optionally substituted with 1-2 halogen substituents; R 5 selected from halogen, cyano, halo-C1-C6-alkyl, halo-C1-C6-alkoxy, C1-C6-alkyl-SO2-, halo-C1-C6-alkyl-SO2-, oxo, group and groups R 6 selected from hydrogen, halogen, cyano and halo-C1-C6-alkyl; R 7 selected from hydrogen and C1-C6 alkyl; R 8a selected from hydrogen and halogen; R 8b selected from hydrogen and halogen; R 9 selected from hydrogen, C1-C6 alkyl and halo-C1-C6 alkyl; R 10selected from hydrogen, C1-C6 alkyl and halo-C1-C6 alkyl; R 11 is hydrogen; and R 12 is a halogen-C1-C6-alkyl.

12. A compound of formula (I) according to claim 11 or a pharmaceutically acceptable salt thereof, wherein: A is selected from: B is selected from phenyl, bicyclo[1.1.1]pentanyl, pyridyl, oxazolyl, pyrimidinyl, pyrazinyl, pyridazinyl, 1,2,4-thiadiazolyl, pyrazolyl, imidazolyl, 1H-1,2,4-triazolyl, triazol-2-yl, 2H-triazolyl, oxazolyl, 1,2,4-oxadiazolyl, 1,3,4-oxadiazolyl, 1,2-dihydropyridyl and 1,2-dihydropyrazinyl; C is selected from cyclopropyl, pyrazolyl, 1,3,4-oxadiazole, pyrazinyl and 1,3,4-thiadiazolyl; L 1 selected from the covalent bond, -CR 8a R 8b - and -CH2O-; L 2 selected from the covalent bond, -NH- and -CH2NH-; X represents NH or O; R1 is a group R 2 represents hydrogen; R 3 represents hydrogen; R 4 represents the group -C(R 4a R 4b R 4c ); each of R 4a , R 4b and R 4c independently represents fluorine; or R 4a and R 4b , taken together with the carbon atom to which they are attached, form cyclopropyl; and R 4c selected from hydrogen, hydroxy and fluorine; wherein said cyclopropyl is optionally substituted with 1-2 fluorine substituents; R 5 selected from chlorine, fluorine, cyano, CF3, 2,2,2-trifluoroethyl, CF3O, methylsulfonyl, CF3-SO2-, oxo, group and groups R 6 selected from hydrogen, fluorine, cyano and CF3; R 7 selected from hydrogen and methyl; R 8a selected from hydrogen and fluorine; R 8bselected from hydrogen and fluorine; R 9 selected from hydrogen, methyl, 2,2-dimethylpropyl, CHF2 and CF3; R 10 selected from hydrogen, methyl and CF3; R 11 is hydrogen; and R 12 represents CF3.

13. A compound of formula (I) or a pharmaceutically acceptable salt thereof, selected from: [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[[1-(trifluoromethyl)cyclopropyl]amino]-3-pyridyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(trifluoromethylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethoxy)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethoxy)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-fluoro-5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[[3-fluoro-5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[(3-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3-fluoro-5-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3-fluoro-5-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)pyrimidin-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)pyrimidin-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)pyridazin-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)pyridazin-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-fluoro-2-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-fluoro-2-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 5-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; 5-[[2-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethylsulfonyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethylsulfonyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-fluoro-2-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[[4-fluoro-2-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(2,4-difluoromethyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(2,4-difluorophenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-fluoro-4-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[[2-fluoro-4-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-methylsulfonyl-4-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-methylsulfonyl-4-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-fluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(5-fluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-fluoro-3-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-methylsulfonyl-3-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[7-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.5]nonan-2-yl]methanone. [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptane-2-yl]-[7-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[2;5]nonane-one [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.4]octan-2-yl]methanone. [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[7-[6-(trifluoromethyl)pyridazine-3-yl]oxy-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[7-[6-(trifluoromethyl)pyridazine-3-yl]oxy-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[3-[6-(4-methyl-4-oxo-1,4λ 5 -azaphosphinan-1-yl)-3-pyridyl]azetidine-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[[1-(trifluoromethyl)cyclopropyl]amino]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[[1-(trifluoromethyl)cyclopropyl]amino]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; N-[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]-3-(trifluoromethyl)benzenesulfonamide; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)pyridazin-3-yl]amino]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1,2,4-thiadiazol-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)oxazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)oxazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)imidazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)imidazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[1-(trifluoromethyl)cyclopropyl]methoxy]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-[[1-(trifluoromethyl)cyclopropyl]methoxy]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(trifluoromethyl)pyrazin-2-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(trifluoromethyl)cyclopropyl]methoxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(trifluoromethyl)cyclopropyl]methoxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(trifluoromethyl)cyclopropyl]amino]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1,2,4-triazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-N-[1-(trifluoromethyl)cyclopropyl]-2-azaspiro[3.3]heptane-6-carboxamide; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[7-[2-(trifluoromethyl)pyrimidine-4-yl]oxy-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[7-[5-(trifluoromethyl)pyrazine-2-yl]oxy-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[5-(trifluoromethyl)pyrazine-2-yl]oxy-2-azaspiro[3.3]heptane-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptane-2-yl]-[6-[5-(trifluoromethyl)pyrazine-2-yl]oxy-2-azaspiro[3.3-yl]heptane-2 [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[(4-methylsulfonylphenyl)methyl]-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[6-(trifluoromethyl)pyridazine-3-yl]oxy-2-azaspiro[3.3]heptane-2-yl]methanone. [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[6-(trifluoromethyl)pyridazin-3-yl]oxy-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(1,1-dioxo-1,4-thiazinan-4-yl)-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[(1,1-dioxothiolan-3-yl)amino]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethyl)azetidin-1-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(2,2,2-trifluoroethyl)azetidin-1-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[4-(trifluoromethylsulfonyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethylsulfonyl)phenyl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[5-cyclopropyl)-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[3-(trifluoromethoxy)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[2-[3-(trifluoromethoxy)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[3-(trifluoromethoxy)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[(6S)-6-[5-(trifluoromethyl)pyrazin-2-yl]oxy-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[4-(trifluoromethoxy)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[2-[4-(trifluoromethoxy)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[4-(trifluoromethoxy)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[2-(trifluoromethoxy)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[2-[2-(trifluoromethoxy)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[2-(trifluoromethyl)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[2-[2-(trifluoromethyl)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[4-fluoro-2-(trifluoromethyl)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[3-(trifluoromethyl)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[2-[3-(trifluoromethyl)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[3-fluoro-5-(trifluoromethyl)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[4-fluoro-3-(trifluoromethyl)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[4-(trifluoromethyl)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[2-[4-(trifluoromethyl)phenyl]sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-(2,4-difluorophenyl)sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-(3,4-difluorophenyl)sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [2-(2-chloro-4-fluorophenyl)sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-(2-methoxyphenyl)sulfonyl-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[[5-(trifluoromethyl)-3-pyridyl]sulfonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(5-chloro-3-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3-chloro-5-fluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-methylsulfonyl-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-methylsulfonyl-3-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(methylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(methylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; (rac)-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; (S)-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; (R)-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; (R)-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; (S)-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(2-fluoro-4-methylsulfonylphenyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)-3-pyridyl]oxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)-3-pyridyl]oxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[6-(trifluoromethyl)pyrazin-2-yl]oxy-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[5-(trifluoromethyl)pyrimidin-2-yl]oxy-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[[3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]sulfonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [7-[(5-chloro-2-pyridyl)methyl]-2-azaspiro[3.5]nonan-2-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [7-[(5-chloro-2-pyridyl)methyl]-2-azaspiro[3.5]nonan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[6-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-[[6-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [7-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.5]nonan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[(5-fluoro-2-pyridyl)methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [7-[(5-fluoro-2-pyridyl)methyl]-2-azaspiro[3.5]nonan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [7-[[6-(difluoromethoxy)-3-pyridyl]methyl]-2-azaspiro[3.5]nonan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[rac-(6S)-6-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[rac-(6R)-6-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[rac-(6R)-6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[rac-(6S)-6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-methylsulfonyl-3-(trifluoromethyl)phenyl]methyl]-2-azaspiro[3.4]octan-2-yl]methanone; 5-[[rac-(6S)-2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.4]octan-6-yl]oxy]-2-(trifluoromethyl)pyridine-4-carbonitrile; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[rac-(6S)-6-[4-methylsulfonyl-3-(trifluoromethyl)phenoxy]-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(2,4-difluorophenyl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[(2,4-difluorophenyl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(2,4-difluorophenyl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3,5-difluorophenyl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)pyridazin-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)pyrimidin-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3,5-difluoro-2-pyridyl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-methylsulfonylphenyl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3-methylsulfonylphenyl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(2-methylsulfonylphenyl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-fluoro-2-(trifluoromethyl)phenyl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 2-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]benzenesulfonamide; methyl 2-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]benzoate; 2-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]benzoic acid; 2-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-N-methylbenzamide; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-[1-(methoxymethyl)-1,2,4-triazol-3-yl]phenyl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-[1-(methoxymethyl)imidazol-2-yl]phenyl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[6-(trifluoromethyl)-3-pyridyl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[2-fluoro-4-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[(4-methylsulfonylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[3-(trifluoromethylsulfonyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[7-[(3-methylsulfonylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[7-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2,7-diazaspiro[3.4]methane-2]-yl [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[7-[[6-(trifluoromethyl)pyridazine-3-yl]methyl]-2,7-diazaspiro[3.4]octane-2-one; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[7-[[5-(trifluoromethyl)pyrazine-2-yl]methyl]-2,7-diazaspiro[3.4]octanone-2]-yl [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[[2-fluoro-4-(trifluoromethyl)phenyl]methylamino]-2-azaspiromethane[3.3]heptane-2-one; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[3-[[4-(trifluoromethyl)phenyl]methylamino]azetidine-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[5-fluoro-2-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]methanone; [3-[[2-chloro-5-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[2-fluoro-4-(trifluoromethoxy)phenyl]methylamino]azetidin-1-yl]methanone; [3-[[2-chloro-4-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[4-(trifluoromethoxy)phenyl]methylamino]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[2-fluoro-4-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[3-fluoro-4-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]methanone; [3-[[3-chloro-5-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[2-fluoro-5-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[4-fluoro-2-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[2-methoxy-4-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]methanone; [3-[[2-fluoro-4-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[[5-chloro-2-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[cyclopropyl-[[2-fluoro-4-(trifluoromethyl)phenyl]methyl]amino]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[cyclopropylmethyl-[[2-fluoro-4-(trifluoromethyl)phenyl]methyl]amino]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; N-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]-3-(trifluoromethyl)benzenesulfonamide; N-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]-2-fluoro-4-(trifluoromethyl)benzenesulfonamide; N-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]-4,4-difluorocyclohexanesulfonamide; N-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]azetidin-3-yl]-3-(trifluoromethoxy)benzenesulfonamide; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[2-fluoro-4-(trifluoromethyl)phenyl]methylamino]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(2,2,2-trifluoroethoxy)pyrazol-1-yl]azetidin-1-yl]methanone; N-[[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]methyl]-3-(trifluoromethyl)benzenesulfonamide; N-[[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]methyl]-4-(trifluoromethyl)benzenesulfonamide; N-[[1-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]methyl]-4-(trifluoromethyl)benzenesulfonamide; N-[[1-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]methyl]-3-(trifluoromethyl)benzenesulfonamide; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-(2,2-dimethylpropylsulfonyl)-2,6-diazaspiro[3.3]heptane-2-sulfonamide; 6-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-N-(1-methylcyclopropyl)-2,6-diazaspiro[3.3]heptane-2-sulfonamide; 6-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-N-[(4-fluorophenyl)methyl]-2,6-diazaspiro[3.3]heptane-2-sulfonamide; 6-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-N-[1-(trifluoromethyl)cyclopropyl]-2,6-diazaspiro[3.3]heptane-2-sulfonamide; 6-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-N-[[1-(trifluoromethyl)cyclopropyl]methyl]-2,6-diazaspiro[3.3]heptane-2-sulfonamide; 1-[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]-2,2,2-trifluoroethanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(trifluoromethyl)pyrazin-2-yl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[(4,4-difluoro-1-piperidyl)methyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(1,1-dioxo-1,4-thiazinan-4-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(trifluoromethyl)cyclopropyl]methylamino]-2-azaspiro[3.3]heptan-2-yl]methanone; N-[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]-1-(trifluoromethyl)cyclopropanecarboxamide; N-[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]-4-(trifluoromethyl)benzenesulfonamide; N-[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]-2-(trifluoromethyl)benzenesulfonamide; N-[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]-2,2-dimethylpropan-1-sulfonamide; [6-[5-cyclopropyl)-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]azetidin-1-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]azetidin-1-yl]methanone; [6-[5-(2,2,2-trifluoro-1-hydroxyethyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]azetidin-1-yl]methanone; [6-[5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]azetidin-1-yl]methanone; [6-[5-[(1S)-2,2,2-trifluoro-1-hydroxyethyl]-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[1-(trifluoromethyl)cyclopropyl]-3-pyridyl]azetidin-1-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[1-(trifluoromethyl)cyclopropyl]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[1-(trifluoromethyl)cyclopropyl]pyrazin-2-yl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[1-(trifluoromethyl)cyclopropyl]pyridazin-3-yl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[2-[1-(trifluoromethyl)cyclopropyl]pyrimidin-5-yl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[1-(trifluoromethyl)cyclopropyl]-2-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]sulfonyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-[[3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]sulfonyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]sulfonyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[2-fluoro-4-(trifluoromethyl)phenyl]sulfonyl-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-fluoro-4-(trifluoromethoxy)phenyl]azetidin-1-yl]methanone; [3-[3-fluoro-4-(trifluoromethoxy)phenyl]azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(trifluoromethylsulfonyl)phenyl]azetidin-1-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(2,2,2-trifluoroethyl)phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[1-(trifluoromethyl)cyclopropyl]methyl]-1,2,4-oxadiazol-5-yl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[1-(trifluoromethyl)cyclopropyl]-1,2,4-oxadiazol-3-yl]azetidin-1-yl]methanone; [3-(2-chloro-4-isopropylsulfonylphenyl)azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; N-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]-4-(trifluoromethyl)benzenesulfonamide; N-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]-4-fluorobenzenesulfonamide; N-[[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]methyl]-4-(trifluoromethyl)benzenesulfonamide; N-[[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]methyl]-4-(trifluoromethoxy)benzenesulfonamide; 4-chloro-H-[[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]methyl]benzenesulfonamide; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[[1-(trifluoromethyl)cyclopropyl]methylamino]-3-pyridyl]azetidin-1-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[[1-(trifluoromethyl)cyclopropyl]methylamino]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[[1-(trifluoromethyl)cyclopropyl]methylamino]pyrazin-2-yl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[[1-(trifluoromethyl)cyclopropyl]methylamino]-2-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[[1-(trifluoromethyl)cyclopropyl]methylamino]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[3-(trifluoromethyl)azetidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[3-(trifluoromethyl)azetidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[3-(trifluoromethyl)azetidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(trifluoromethyl)azetidin-1-yl]phenyl]azetidin-1-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(trifluoromethyl)azetidin-1-yl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[2-[3-(trifluoromethyl)azetidin-1-yl]pyrimidin-5-yl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[2-[3-(trifluoromethyl)pyrrolidin-1-yl]pyrimidin-5-yl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[2-[(311)-3-(trifluoromethyl)pyrrolidin-1-yl]pyrimidin-5-yl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[2-[(38)-3-(trifluoromethyl)pyrrolidin-1-yl]pyrimidin-5-yl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[(38)-3-(trifluoromethyl)pyrrolidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[(3R)-3-(trifluoromethyl)pyrrolidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[rac-(3R)-3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[rac-(3S)-3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[[1-(trifluoromethyl)cyclopropyl]amino]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclobutyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[[1-(trifluoromethyl)cyclopropyl]amino]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[[1-(trifluoromethyl)cyclopropyl]amino]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[3-hydroxy-3-(trifluoromethyl)azetidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(3,5-diisopropylpyrazol-1-yl)phenyl]azetidin-1-yl]methanone; [3-[4-(3-tert-butyl-5-methylpyrazol-1-yl)phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]azetidin-1-yl]methanone; (4R)or(4S)-1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]-4-(trifluoromethyl)piperidin-2-one; (4S)or(4R)-1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]-4-(trifluoromethyl)piperidin-2-one; [7-(5-chloro-3-fluoro-2-pyridyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-[3-(difluoromethyl)cyclobutyl]phenyl]azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [7-(4-chloro-2-fluorophenyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]-4-(trifluoromethyl)pyridin-2-one; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(difluoromethyl)-5-methylpyrazol-1-yl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-(5-spiro[3.3]heptan-2-ylpyrazin-2-yl)azetidin-1-yl]methanone; [3-[4-(5-cyclopropyl-3-methylpyrazol-1-yl)phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-(3-cyclopropyl-5-methylpyrazol-1-yl)phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(2,2-difluoro-5-azaspiro[2.4]heptan-5-yl)-3-pyridyl]azetidine-1-ylamethanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(6-oxa-2-azaspiro[3.4]octan-2-yl)-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-hydroxy-3-(trifluoromethyl)cyclobutyl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[3-(trifluoromethyl)azetidin-1-yl]-2-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(5-oxa-2-azaspiro[3.4]octan-2-yl)-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-(hydroxymethyl)cyclopropyl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(2-oxaspiro[3.3]heptan-6-yl)-3-pyridyl]azetidin-1-yl]methanone4-methylbenzenesulfonic acid; [3-(4-cyclobutyl-3-methylsulfonylphenyl)azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[3-(1-hydroxy-1-methylethyl)azetidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(2,2-dimethylpropyl)-3-pyridyl]azetidin-1-yl]methanone; (trans)-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[3-(trifluoromethyl)cyclobutyl]-3-pyridyl]azetidin-1-yl]methanone; (trans)-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[3-(difluoromethyl)cyclobutyl]-3-pyridyl]azetidin-1-yl]methanone; [3-[6-(2-azaspiro[3.4]octan-2-yl)-3-pyridyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(2-oxa-7-azaspiro[3.4]octan-7-yl)-3-pyridyl azetidin-1-yl]methanone; trans-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(difluoromethyl)cyclobutyl]phenyl]azetidin-1-yl]methanone; cis-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(difluoromethyl)cyclobutyl]phenyl]azetidin-1-yl]ethanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-hydroxy-3-[4-[3-(trifluoromethyl)azetidin-1-yl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[2-methoxy-4-(trifluoromethyl)phenyl]methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[2-methoxy-4-(trifluoromethyl)phenyl]methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[2-fluoro-4-(trifluoromethylsulfonyl)phenyl]methoxy]azetidin-1-yl]methanone; 2-cyclopropyl-6-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]oxybenzonitrile; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3heptan-2-yl]-[3-[[2-fluoro-4-(trifluoromethyl)phenyl]methoxy]azetidin-1-yl]methanone; [3-(4-cyclopropylphenoxy)azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-(4-cyclopropyl-2-fluorophenoxy)azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(trifluoromethyl)pyridazin-3-yl]oxyazetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[4-(trifluoromethoxy)phenyl]methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[4-(trifluoromethylsulfonyl)phenyl]methoxy]azetidin-1-yl]methanone; 5-cyclopropyl-2-[1-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]oxybenzonitrile; methyl 2-[3-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]oxyphenyl]-2-methylpropanoate; [3-[3-cyclopropyl-4-(trifluoromethyl)phenoxy]azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[(2-chloro-4-fluorophenyl)methoxy]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[3-(trifluoromethylsulfonyl)phenyl]methoxy]azetidin-1-yl]methanone; [3-(3-cyclopropyl-2-fluorophenoxy)azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(trifluoromethyl)phenoxy]azetidin-1-yl]methanone; [3-[[2-fluoro-4-(trifluoromethyl)phenyl]methoxy]azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-(4-chloro-3-cyclopropylphenoxy)azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3[(4,4-difluorocyclohexyl)methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3[(6,6-difluoro-3-bicyclo[3.1.0]hexanyl)methoxy]azetidin-1-yl]methanone; [3-[(6-chloro-5-cyclopropyl-3-pyridyl)oxy]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3[[5-(trifluoromethyl)-3-pyridyl]methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3[(2-fluoro-4-methylsulfonylphenyl)methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3[[1-(trifluoromethyl)cyclopropyl]methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3[[6-(trifluoromethyl)-3-pyridyl]methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3[(4-methylsulfonylphenyl)methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3[(3-methylsulfonylphenyl)methoxy]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3[(2-methylsulfonylphenyl)methoxy]azetidin-1-yl]methanone; [3-[[2-fluoro-4-(trifluoromethyl)phenyl]methoxy]azetidin-1-yl]-[6-[5-(2,2,2-trifluoro-1-hydroxyethyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-(4-chloro-2-methylsulfonylphenyl)phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-(2-chloro-4-methylsulfonylphenyl)phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3,3heptan-2-yl]methanone; methyl 2-[4-[1-[6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]benzoate; 2-[4-[1-[6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]benzamide; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[[1-(trifluoromethyl)cyclopropyl]amino]methyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[1-(trifluoromethyl)cyclopropyl]methylamino]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-(2,2-dimethylpropyl)-1,3,4-oxadiazol-2-yl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-(2,2,2-trifluoroethyl)-1,3,4-oxadiazol-2-yl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [3-[3-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [7-(2,5-dichlorophenoxy)-2-azaspiro[3.5]nonan-2-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[2-fluoro-4-(trifluoromethyl)phenoxy]methyl]azetidin-1-yl]methanone; 5-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.5]nonan-7-yl]-3-(trifluoromethoxy)benzenesulfonamide; [3-[2-[2-fluoro-4-(trifluoromethyl)phenyl]ethyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [7-(5-chloro-2-methylsulfonylphenoxy)-2-azaspiro[3.5]nonan-2-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)pyrazin-2-yl]amino]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[[1-(trifluoromethyl)cyclopropyl]methylamino]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[(2-chloro-4-fluorophenoxy)methyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[[3-(trifluoromethyl)oxetan-3-yl]amino]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-(4-fluoro-2-methylsulfonylphenoxy)-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(2-chloro-4-fluorophenyl)sulfonyl-2-azaspiro[3.3]heptan-2-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[(3-methyl-1,1-dioxothiethan-3-yl)amino]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; N-[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.5]nonan-7-yl]-4,4-difluorocyclohexanesulfonamide; 2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-N-[[1-(trifluoromethyl)cyclopropyl]methyl]-2-azaspiro[3.3]heptane-6-carboxamide; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[1-[[4-(trifluoromethyl)phenyl]methyl]azetidin-3-yl]azetidin-1-yl]methanone; [3-[(4-chlorophenyl)methyl]azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; 2-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]-2-(4-fluorophenyl)acetamide; [(3aR,6aS)-2-benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[(1,1-dioxothiethan-3-yl)amino]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-[1-(2-tert-butyltetrazol-5-yl)cyclopropyl]phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(2,2,2-trifluoro-1,1-dimethylethoxy)phenyl]azetidin-1-yl]methanone; [3-[6-(2-chlorophenoxy)-3-pyridyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(2,2,2-trifluoro-1,1-dimethylethoxy)phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(2,2-dimethylpropyl)triazol-4-yl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[5-(trifluoromethyl)pyrazin-2-yl]oxyphenyl]azetidin-1-yl]methanone; [3-[4-(benzenesulfonyl)phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; methyl-1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]cyclopropanecarboxylate; [3-(4-cyclohexylsulfonylphenyl)azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[6-(2-chlorophenoxy)-3-pyridyl]azetidin-1-yl]-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[[1-(trifluoromethyl)cyclopropyl]methoxy]phenyl]azetidin-1-yl]methanone; 1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]cyclopropanecarbonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[5-[1-(trifluoromethyl)cyclopropyl]-4H-1,2,4-triazol-3-yl]phenyl]azetidin-1-yl]methanone; [3-[6-(2-chlorophenoxy)pyridazin-3-yl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-(1H-tetrazol-5-yl)cyclopropyl]phenyl]azetidin-1-yl]methanone; 4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]azetidin-3-yl]benzenesulfonamide; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(dimethylphosphorylmethyl)phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(4-isopropyl-N-methylaniline)-3-pyridyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[6-(N-methylaniline)-3-pyridyl]azetidin-1-yl]methanone; 1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]piperidine-2-carboxamide; 1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]-4,4-difluoropiperidine-2-carboxamide; 1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidine-3-yl]phenyl]pyrrolidin-2-carboxamide; 2-[3-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidine-3-yl]oxyphenyl]-2-methylpropanoic acid; [3-[[2-fluoro-4-(trifluoromethyl)phenyl]methoxy]azetidine-1-yl]-[6-[5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]-4H-1,2,4-triazol-3-yl]-2-methaspiropane]-ylgeropan[3.3] [3-[[2-fluoro-4-(trifluoromethyl)phenyl]methoxy]azetidine-1-yl]-[6-[5-[(1S)-2,2,2-trifluoro-1-hydroxyethyl]-4H-1,2,4-triazol-3-yl]-2-methaspiropane]-ylgerotan[3.3] 2-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidine-3-yl]phenyl]benzoic acid; 2-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidine-3-yl]phenyl]-N-ethylbenzamide; 1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]azetidin-3-yl]phenyl]cyclopropanecarboxylic acid; 1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]azetidin-3-yl]phenyl]cyclopropanecarboxamide; (2S)-1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]piperidine-2-carboxamide; (2S)-1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]-4,4-difluoropiperidine-2-carboxamide; (2R)-1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]-4,4-difluoropiperidine-2-carboxamide; (2S)-1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]azetidin-3-yl]phenyl]pyrrolidine-2-carboxamide; (2R)-1-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidine-3-yl]phenyl]pyrrolidin-2-carboxamide; [3-(6-tert-butyl-3-pyridyl)azetidine-1-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-yl]methanone; [[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[[6-(trifluoromethyl)pyrimidine-4-yl]methyl]-2-azaspiromethane[3.3]heptanone;yl]-yl] [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[[1-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptanone;2-yl]methane [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[[2-(trifluoromethyl)pyrimidine-4-yl]methyl]-2-azaspiro[3.3]heptane-ona;yl] [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[[4-(trifluoromethyl)pyrimidine-2-yl]methyl]-2-azaspiro[3.3]heptane-one;yl] [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1H-pyrazol-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-cyclopropyl-3-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)-2-pyridone; bis[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]azetidin-1-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-ylidene]methyl]-5-(trifluoromethyl)-2-pyridone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)triazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)triazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(4-triflylphenyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [2-(4-chloro-2-mesylbenzyl)-6-azaspiro[3.4]octan-6-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(2-tert-butylthiazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [4-[5-chloro-1-(2-hydroxy-2-methylpropyl)indazol-3-yl]piperidino]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)-2-pyridone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[3-[5-[1-(trifluoromethyl)cyclopropyl]-1,3,4-oxadiazol-2-yl]-1-bicyclo[1.1.1]pentanyl]piperidino]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(4-triflylphenyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(4-triflulylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-[3-(trifluoromethyl)phenyl]sulfonyl-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-[1-(trifluoromethyl)cyclopropyl]-1,3,4-oxadiazol-2-yl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(trifluoromethyl)thiazol-2-yl]oxy-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]oxy-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-1-(2,2,2-trifluoroethyl)-2-pyridone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(4-triphenylbenzyl)-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-methyl-5-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[4-(trifluoromethyl)phenyl]sulfonimidoyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)thiazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[[1-(trifluoromethyl)cyclopropyl]methoxy]pyrazin-2-yl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)isothiazol-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; 5-[[2-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-2-(trifluoromethyl)isonicotinnitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-fluoro-2-pyridyl)oxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[3-(trifluoromethyl)phenyl]sulfonyl-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl]methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)triazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [3-[3-[[2-fluoro-4-(trifluoromethyl)phenyl]methyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[3-(5-neopentyl-1,3,4-oxadiazol-2-yl)-1-bicyclo[1.1.1]pentanyl]piperidino]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1,2,4-triazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)triazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[[[1-(trifluoromethyl)cyclopropyl]amino]methyl]pyrazin-2-yl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1,2,4-triazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[difluoro-[6-(trifluoromethyl)pyridazin-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-[1-(trifluoromethyl)cyclopropyl]-1,3,4-thiadiazol-2-yl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[difluoro-[6-(trifluoromethyl)pyridazin-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(1-hydroxycyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(5-ethoxy-3-methylpyrazol-1-yl)phenyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1,2,4-thiadiazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(2-fluoro-4-triphenylbenzyl)-2,6-diazaspiro[3.3]heptan-2-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)pyridazin-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)imidazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-(4-chloro-2-mesylphenyl)phenyl]azetidin-1-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-fluoro-5-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[3-(trifluoromethyl)phenyl]sulfonimidoyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-methyl-4-(trifluoromethyl)thiazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[3-(trifluoromethoxy)phenyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)pyridazin-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[2-methyl-4-(trifluoromethyl)pyrazol-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(4-dimethylphosphoryl-2-fluorobenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; 2-[3-[1-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]-1-bicyclo[1.1.1]pentanyl]-5-fluorobenzonitrile; 3-[[2-[6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)benzonitrile; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[3-[5-(2,2-dimethylpropyl)-1,3,4-thiadiazol-2-yl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[2-fluoro-4-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[4-fluoro-2-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[[1-(trifluoromethyl)cyclopropyl]methoxy]pyrazin-2-yl]azetidin-1-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-(2-fluoro-4-triphenylbenzyl)oxyazetidin-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[1-(trifluoromethyl)cyclopropyl]-2-pyridyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[[5-(trifluoromethyl)pyrazin-2-yl]amino]-1-bicyclo[1.1.1]pentanyl]methanone; [6-[3-(1-aminocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[(8S)-8-methyl-8-oxo-8λ 6 -thia-9-azatricyclo[8.4.0.02,7]tetradeca-1(10),2(7),3,5,8,11,13-heptaen-12-yl]azetidin-1-yl]methanone; 2-[[2-[6-[5-(1-hydroxycyclopropyl)-4N-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)benzonitrile; [6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[(811)-8-methyl-8-oxo-8λ6 -thia-9-azatricyclo[8.4.0.02,7]tetradeca-1(10),2(7),3,5,8,11,13-heptaen-12-yl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-4-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-6-ketonicotinonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[2-(methylsulfonimidoyl)-4-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-(3-triflylbenzyl)-2,7-diazaspiro[3.4]octan-2-yl]methanone; [6-[(4-tert-butyloxazol-2-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethoxy)phenyl]sulfonyl-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-3-fluorobenzonitrile; [6-[(5-tert-butyl-1,3,4-thiadiazol-2-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(4-cyclopropylthiadiazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)thiazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[4-(trifluoromethoxy)phenyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(5-neopentyl-1,3,4-thiadiazol-2-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(methylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1N-1,2,4-triazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(difluoromethyl)-1N-pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-(cyclopropylsulfonimidoyl)phenyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(5-fluoro-3-pyridyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[4-[3-(5-neopentyl-1,3,4-oxadiazol-2-yl)-1-bicyclo[1.1.1]pentanyl]piperidino]methanone; 5-[[2-[6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]oxy]-2-(trifluoromethyl)benzonitrile; [6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(4-mesylpyrazol-1-yl)phenyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethoxy)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-(2-fluoro-4-trifluorobenzyl)oxyazetidin-1-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[[1-(trifluoromethyl)cyclopropyl]methylamino]pyrazin-2-yl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-4-(trifluoromethyl)thiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(4-cyclopropylsulfonylbenzyl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(difluoromethyl)thiazol-2-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-fluoro-5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 5-fluoro-2-[3-[1-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]-1-bicyclo[1.1.1]pentanyl]benzonitrile; 1-[[2-[6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-ketonicotinnitrile; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 5-[[2-[6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-3-(trifluoromethyl)-2-cyanopyridine; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(trifluoromethyl)pyrazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [3-[3-(3-cyclopropyl-1H-pyrazol-5-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1N-pyrazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(2-mesylphenyl)phenyl]azetidin-1-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-fluoro-5-trifluorobenzyl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(1-hydroxycyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[1-(2-hydroxyethyl)-5-(trifluoromethyl)indazol-3-yl]piperidino]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-3-pyridyl]oxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)tetrazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[2-fluoro-4-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)-1H-imidazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)-1N-pyrazol-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(4-triflylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[2-fluoro-4-(trifluoromethyl)phenyl]methyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[1-(trifluoromethyl)cyclopropyl]methylsulfonyl]-1-bicyclo[1.1.1];pentanyl]azetidin-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[3-(trifluoromethoxy)phenyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)isothiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethoxy)phenyl]sulfonyl-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(difluoromethyl)-5-methyl-1,2,4-triazol-1-yl]phenyl]azetidin-1-yl]methanone; 5-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-3-(trifluoromethyl)-2-cyanopyridine; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)thiazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 5-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-1-methylimidazol-4-carbonitrile; [2-(4-chloro-2-mesylphenyl)-6-azaspiro[3.4]octan-6-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(4-triflylphenyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; 5-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-pyridone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(1-methylpyrazol-4-yl)oxy-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[(6S)-6-(3-triflylbenzyl)-2-azaspiro[3.4]octan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)isoxazol-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(2,2,2-trifluoroethyl)tetrazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 5-[[2-[6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)triazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-(3-triflylbenzyl)-2,7-diazaspiro[3.4]octan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-[4-(trifluoromethyl)phenyl]sulfonyl-2-azaspiro[3.5]nonan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[4-(trifluoromethoxy)phenyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-(trifluoromethyl)pyrazin-2-yl]oxy-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-ethyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(2-fluoro-4-triflylbenzyl)-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(trifluoromethylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 2-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)benzonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-[1-(trifluoro methyl)cyclopropyl]-1,3,4-thiadiazol-2-yl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(trifluoromethylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(3-ethoxy-5-methylpyrazol-1-yl)phenyl]azetidin-1-yl]methanone; [6-[3-(1-Hydroxycyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-triflyl-3-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-Difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)isothiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [3-[3-(4-chloro-2-mesylphenyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]azetidin-1-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(trifluoromethylsulfonimidoyl)phenyl]azetidin-1-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)pyrimidin-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethoxy)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]pyrazole-4-carbonitrile; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[6-(trifluoromethyl)-3-pyridyl]methyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)-3-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 3-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-1-(2,2,2-trifluoroethyl)-2-pyridone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-[1-(t fluoromethyl)cyclopropyl]-1,3,4-oxadiazol-2-yl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethoxy)phenyl]sulfonimidoyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[2-fluoro-4-(trifluoromethylsulfonimidoyl)benzyl]oxyazetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [2-(4-chloro-2-mesylphenyl)-6-azaspiro[3.4]octan-6-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[1-(trifluoromethyl)-cyclopropyl]methylamino]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; 3-[[2-[6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)benzonitrile; 4-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-methylpyrazole-3-sulfonamide; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-(2,2-dimethylpropyl)-1,3,4-thiadiazol-2-yl]-1-bicyclo[1.1.1]-pentanyl]azetidin-1-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(4-mesylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(5-neopentyl-1,3,4-thiadiazol-2-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[2-fluoro-4-(trifluoromethyl)benzyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 5-[[2-[6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-(2,4-difluorobenzyl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[3-(5-cyclopropyl-3-methylpyrazol-1-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[3-(5-cyclopropyl-3-methylpyrazol-1-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1H-pyrazol-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-[(4-tert-butylisoxazol-3-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]oxy-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[5-(trifluoromethyl)pyrazin-2-yl]amino]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[(6R)-6-(3-triphenylbenzyl)-2-azaspiro[3.4]octan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(3-methyl-1H-pyrazol-5-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)thiazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(2,2-difluoroethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)thiazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[(68)-6-(4-triflylbenzyl)-2-azaspiro[3.4]octan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[5-(methylamino)-1,3,4-thiadiazol-2-yl]phenyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(trifluoromethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(trifluoromethylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-triflulylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]oxy]-2-(trifluoromethyl)benzonitrile; 5-[[2-[6-[5-(1-hydroxycyclopropyl)-4H-1,2,4-triazol-3-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-2-(trifluoromethyl)nicotinonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(4-cyclobutylthiadiazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)isoxazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(difluoromethyl)-1H-pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 5-[[(6S)-2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.4]octan-6-yl]methyl]-2-(trifluoromethyl)isonicotinenitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[(6S)-6-(4-triflylbenzyl)-2-azaspiro[3.4]octan-2-yl]methanone; [6-[(5-chloro-3-fluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(5-cyclobutyl-1H-pyrazol-3-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[[5-(difluoromethyl)-1H-pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-triflyl-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3-chloro-5-fluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[(5-chloro-2-pyridyl)oxy]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[[3-fluoro-5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-5-(trifluoromethyl)-2-pyridone; [6-[(3-chloro-5-fluoro-2-pyridyl)oxy]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(5-cyclopropyl-2-methylpyrazol-3-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(difluoromethyl)thiazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1H-pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-([1,2,4]triazolo[1,5-a]pyridin-6-ylmethyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-triflulylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(difluoromethyl)pyrazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[2-(trifluoromethyl)pyrimidin-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]oxy-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[2-fluoro-4-(trifluoromethylsulfonimidoyl)benzyl]oxyazetidin-1-yl]methanone; [6-[2-mesyl-4-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]azetidin-1-yl]methanone; [6-[3-(1-aminocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[4-fluoro-2-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3-cyclopropyl-1,2,4-thiadiazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(trifluoromethylsulfonimidoyl)phenyl]azetidin-1-yl]methanone; [6-[3-(1-Hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1H-imidazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)oxazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)thiazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[(3-cyclopropyl-1H-pyrazol-5-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-([1,2,4]triazolo[1,5-a]pyridin-6-ylmethyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[6-[3-hydroxy-3-(trifluoromethyl)azetidin-1-yl]-3-pyridyl]azetidin-1-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(3-hydroxy-1,2,4-triazol-1-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-fluoro-5-(trifluoromethylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(difluoromethyl)thiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-triflyl-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[(611)-6-(4-triflylbenzyl)-2-azaspiro[3.4]octan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(3-fluoro-5-triflylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)isothiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-4-(trifluoromethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[(4-tert-butyl-1H-imidazol-2-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(methylsulfonimidoyl)-5-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)isoxazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-4-(trifluoromethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-fluoro-5-(trifluoromethyl)-2-pyridyl]oxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[2-[(311)-3-(trifluoromethyl)pyrrolidino]pyrimidin-5-yl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-l,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[(6R)-6-(4-triflylbenzyl)-2-azaspiro[3.4]octan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 5-[[(6R)-2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.4]octan-6-yl]methyl]-2-(trifluoromethyl)isonicotinenitrile; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-mesyl-5-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)isoxazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[3-(4-fluorophenyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)isothiazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[(5-chloro-3-fluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-fluoro-5-(trifluoromethyl)-2-pyridyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(2,2,2-trifluoroethyl)-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(3-dimethylphosphoryl-5-fluorobenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(trifluoromethyl)-2-pyridyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-pyrazolo[4,3-b]pyridin-5-ylmethyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(4-fluoro-2-mesylphenyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[(3-cyclopropyl-5-methylisoxazol-4-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(2,2,2-trifluoroethyl)triazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(2,2,2-trifluoroethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-4-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-pyrazolo[4,3-b]pyridin-5-yl]methyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)oxazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[5-(trifluoromethyl)pyrimidin-2-yl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(2,2,2-trifluoroethyl)-1,2,4-oxadiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 5-[[(6S)-2-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.4]octan-6-yl]oxy]-2-(trifluoromethyl)isonicotinnitrile; [6-[3-(1-Hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(trifluoromethylsulfonimidoyl)phenyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)imidazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[5-(trifluoromethyl)pyrazin-2-yl]-amino]-1-bicyclo[1.1.1]-pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)isothiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)oxazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [3-[3-(3-cyclopropyl-1H-pyrazol-5-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-(4-triphenylbenzyl)-2,7-diazaspiro[3.4]octan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)thiazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(3-fluoro-5-methoxyphenyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro-[3.3]heptan-2-yl]-[4-[3-[5-[1-(trifluoromethyl)cyclopropyl]-1,3,4-oxadiazol-2-yl]-1-bicyclo-[1.1.1]pentanyl]piperidino]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-(trifluoromethyl)pyrazin-2-yl]oxy-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[2-[(3S)-3-(trifluoromethyl)pyrrolidino]pyrimidin-5-yl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(trifluoromethyl)imidazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethoxy)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-[1-(trifluoromethyl)cyclopropyl]-pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[3-(3,5-dimethylpyrazol-1-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)isothiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-(4-triflylbenzyl)-2,7-diazaspiro[3.4]octan-2-yl]methanone; [6-[2-fluoro-4-(trifluoromethylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(2,2,2-trifluoroethyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 3-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-pyridone; 1-[[2-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]pyrazol-4-carbonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-5-(trifluoromethyl)triazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethoxy)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[4-(trifluoromethyl)phenyl]sulfonyl-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[4-(trifluoromethyl)phenyl]sulfonyl-2-azaspiro[3.5]nonan-2-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(difluoromethoxy)-2-pyridone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(3,5-dimethylpyrazol-1-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[(6S)-6-(3-triflylbenzyl)-2-azaspiro[3.4]octan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-triflylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(trifluoromethylsulfonimidoyl)phenoxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-triflyl-3-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[4-(trifluoromethyl)thiazol-2-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-[[3-(cyclopropylmethyl)-1,2,4-oxadiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[4-fluoro-2-(methylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[5-(trifluoromethyl)-2-pyridyl]oxy]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[(5-chloro-3-fluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-[1-( trifluoromethyl)cyclopropyl]-1,3,4-oxadiazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethylsulfonimidoyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(4-tert-butylthiazol-2-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[(6R)-6-(3-triflylbenzyl)-2-azaspiro[3.4]octan-2-yl]methanone; [6-[3-fluoro-5-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(1,1-difluoroethyl)-1,2,4-oxadiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-(cyclopropylsulfonimidoyl)phenyl]azetidin-1-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1,2,4-triazol-1-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)-1H-pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 3-[[2-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-5-(trifluoromethyl)benzonitrile; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro-[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [3-[4-(3,5-diisopropylpyrazol-1-yl)phenyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; 3-fluoro-4-[[2-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]benzonitrile; [6-[3-mesyl-4-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[4-fluoro-2-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(4-triphenylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [7-[(5-chloro-2-pyridyl)methyl]-2-azaspiro[3.5]nonan-2-yl]-[6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethoxy)-2-pyridone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)isoxazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 3-[[2-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)benzonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(5-fluoro-3-pyridyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3-ethyl-1,2,4-thiadiazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)oxazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-4-(trifluoromethyl)pyridin-2-one; 5-chloro-2-[3-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]azetidin-3-yl]-1-bicyclo[1.1.1]pentanyl]-N-ethylbenzamide; [6-[2-fluoro-4-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethoxy)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-[3-(oxetan-3-yl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; 4-[[2-[6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-3-fluorobenzonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(4-fluorophenyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(oxetan-3-yl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(1-mesylcyclopropyl)phenyl]azetidin-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-4-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-6-(trifluoromethyl)-2-cyanopyridine; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)thiazol-2-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(2-mesylphenyl)phenyl]azetidin-1-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethylsulfonimidoyl)phenyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)thiazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)thiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(4-methylsulfonylphenyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-[1-(trifluoromethyl)cyclopropyl]-1,2,4-triazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3-chloro-5-fluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(1-mesylcyclopropyl)phenyl]azetidin-1-yl]methanone; [6-(4-mesylbenzyl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-[1-(trifluoromethyl)cyclopropyl]-1,3,4-oxadiazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1H-imidazol-4-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 3-fluoro-4-[[2-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]benzonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[difluoro-[4-(trifluoromethyl)phenyl]methyl]-1-bicyclo[1.1.1]-pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-pyrazol-3-ylmethyl)-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [3-[3-(5-neopentyl-1,3,4-thiadiazol-2-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]pyrazole-4-carbonitrile; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(2,5-dimethylthiazol-4-yl)phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[2-mesyl-4-(trifluoromethyl)phenyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[6-(trifluoromethyl)-3-pyridyl]methyl]-2,7-diazaspiro[3.4]octan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[6-(trifluoromethyl)-3-pyridyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(4-methylimidazol-1-yl)phenyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[5-(trifluoromethyl)-2-pyridyl]sulfonyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; 5-[[2-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-mesyl-5-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[[5-(trifluoromethyl)pyrazin-2-yl]amino]cuban-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(3-neopentyltriazol-4-yl)phenyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-trifluoromethyl-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.5]nonan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-[1-(trifluoromethyl)cyclopropyl]-1H-1,2,4-triazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(4-mesylbenzyl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(difluoromethyl)-5-methylpyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-(3-tert-butyl-5-methylpyrazol-1-yl)phenyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[4-(3-cyclopropyl-5-methylpyrazol-1-yl)phenyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3-cyclopropylpyrazol-1-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]phenyl]azetidin-1-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[1-(trifluoromethyl)cyclopropyl]methylamino]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[difluoro-[6-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[2-mesyl-4-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; 6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-N-[[6-(trifluoromethyl)-3,4-diazatricyclo[7.1.1.03,7]undeca-4,6-dien-1-yl]methyl]-2-azaspiro[3.3]heptane-2-carboxamide; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[6-(trifluoromethyl)-3-pyridyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(trifluoromethylsulfonimidyoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(5-chloro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro [3.3]heptan-2-yl]methanone; [3-[4-(4-cyclopropylimidazol-1-yl)phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; 5-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)nicotinnitrile; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]phenyl]azetidin-1-yl]methanone; [6-(2,4-difluorobenzyl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(oxetan-3-yl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[2-[[3-methyl-5-(trifluoromethyl)-2-pyridyl]oxy]-7-azaspiro[3.5]nonan-7-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)triazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-dimethylphosphoryl-2-methylpyrazol-3-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [3-[4-[5-cyclopropyl-3-(difluoromethyl)pyrazol-1-yl]phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[4-(1-hydroxyethyl)-5-methylthiazol-2-yl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(3,5-dimethyl-1,2,4-triazol-1-yl)phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[[6-(trifluoromethyl)-3-pyridyl]methyl]piperazino]methanone; 5-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)isonicotine nitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[fluoro-[6-(trifluoromethyl)pyridin-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(5-cyclopropyl-3-methylpyrazol-1-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3-cyclopropyl-5-methylpyrazol-1-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethylsulfonimidoyl)phenoxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[2-fluoro-4-(trifluoromethylsulfonimidyoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(4-trifluoromethyl)-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(trifluoromethyl)-1H-pyrazol-5-yl]phenyl]azetidin-1-yl]methanone; [6-[3-(1-aminocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[2-fluoro-4-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 5-[[2-[6-[3-(1-aminocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; 3-[[2-[6-[3-(1-aminocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)benzonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-3-(trifluoromethyl)pyrrolo[2,3-b]pyridin-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(trifluoromethoxy)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2-hydroxyethyl)-3-(trifluoromethyl)pyrrolo[2,3-b]pyridin-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(4-cyclopropylsulfonylbenzyl)-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-[1-(trifluoromethyl)cyclopropyl]-imidazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]oxymethyl]-3-methoxybenzonitrile; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-[1-(trifluoromethyl)cyclopropyl]-1,3,4-oxadiazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-dimethylphosphoryl-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [4-[5-chloro-1-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]indazol-3-yl]piperidino]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [4-[5-chloro-1-[(2R)-3,3,3-trifluoro-2-hydroxypropyl]indazol-3-yl]piperidino]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[6-(trifluoromethyl)-3-pyridyl]methyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; 3-[[2-[6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)benzonitrile; [7-(4-chloro-2-mesylphenyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [4-[6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]piperazino]-(4-ethylphenyl)methanone; [4-[6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]piperazine]-[5-(2-pyridyl)-2-thienyl]methanone; [4-[6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]piperazine]-[4-(methylamino)phenyl]methanone; [4-[6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]piperazino]-(4-methyl-2-thienyl)methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(trifluoromethyl)pyrazol-1-yl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [3-[4-[3-cyclopropyl-5-(difluoromethyl)pyrazol-1-yl]phenyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[[5-(trifluoromethyl)-2-pyridyl]methyl]piperazino]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(2,4-dimethylthiazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[(5-chloro-1,3-dimethylpyrazol-4-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[(2-methyloxazol-4-yl)methyl]piperazino]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[(4-methylthiazol-5-yl)methyl]piperazino]methanone; [4-[(5-chloro-1,3-dimethylpyrazol-4-yl)methyl]piperazino]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-3-(trifluoromethyl)benzonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(difluoromethyl)-3-methylpyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[3-dimethylphosphoryl-5-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]oxymethyl]-3-methoxybenzamide; [6-[(3-tert-butyl-1,2,4-oxadiazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(pyrazolo[1,5-a]pyridin-3-ylmethyl)-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[2-mesyl-4-(trifluoromethyl)benzyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[4-dimethylphosphoryl-2-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[(4-chloro-2-methoxybenzyl)-methylamino]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [2-(4-chloro-2-mesylbenzyl)-6-azaspiro[3.4]octan-6-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [4-[(4-chloro-2-methoxybenzyl)-methylamino]piperidino]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[[(4-chloro-2-methoxybenzyl)-methylamino]methyl]azetidin-1-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-methylthiazol-2-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(2-methylthiazol-4-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(1,5-dimethylpyrazol-4-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(2,4-dimethyloxazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 5-chloro-2-[[1-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]methoxy]nicotinamide; [6-[(3-cyclopropyl-1H-pyrazol-5-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(2-methylpyrazol-3-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(1-methylpyrazol-3-yl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[[6-(trifluoromethyl)-3-pyridyl]oxymethyl]piperidino]methanone; 4-[[1-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]oxymethyl]-2-methoxybenzonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[2-fluoro-4-(trifluoromethoxy)benzyl]oxypiperidino]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[2-fluoro-4-(trifluoromethyl)benzyl]oxypiperidino]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[2-mesyl-4-(trifluoromethyl)benzyl]-oxypiperidino]methanone; 5-chloro-2-[[1-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]methoxy]nicotine nitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(2-methylsulfonylphenyl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; 4-[4-[1-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]phenyl]-1H-triazol-5-carbonitrile; 4-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethoxy)benzoic acid methyl ester; methyl ester of 5-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethoxy)benzoic acid; 4-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethoxy)benzamide; 5-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethoxy)benzamide; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[[2-mesyl-4-(trifluoromethyl)phenoxy]-methyl]piperidino]methanone; [4-[[4-fluoro-3-(trifluoromethyl)phenoxy]methyl]piperidino]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[[2-mesyl-4-(trifluoromethoxy)phenoxy]methyl]piperidino]methanone; [4-(2-chloro-4-mesylbenzyl)oxypiperidino]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[4-[[2-mesyl-4-(trifluoromethyl)phenoxy]methyl]-piperidino]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(4-trifluorobenzyl)-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [4-[[3-fluoro-5-(trifluoromethyl)phenoxy]methyl]piperidino]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[4-[[4-mesyl-3-(trifluoromethyl)phenoxy]-methyl]piperidino]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[4-[[2-mesyl-4-(trifluoromethoxy)phenoxy]methyl]-piperidino]methanone; [6-(5-cyclopropyl-1H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[4-[[4-mesyl-3-(trifluoromethyl)phenoxy]-methyl]piperidino]methanone; [4-(2-chloro-4-mesylbenzyl)oxypiperidino]-[6-(5-cyclopropyl-1H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(4-dimethylphosphorylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.4]octan-2-yl]methanone; [3-[3-[(5-cyclopropyl-1,3,4-oxadiazol-2-yl)methyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.4]octan-2-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(trifluoromethyl)-1,2,4-triazol-1-yl]phenyl]azetidin-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(4-fluorophenyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [2-(4-chloro-2-fluorophenyl)-6-azaspiro[3.4]octan-6-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [2-(4-chloro-2-fluorophenyl)-6-azaspiro[3.4]octan-6-yl]-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[3-[4-(3-cyclopropyl-1,2,4-triazol-1-yl)phenyl]azetidine-1-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[(3-dimethylphosphorylphenyl)methyl]-2-azaspiro[3.3]heptane-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-(5-fluoro-3-pyridyl)-2,6-diazaspiro[3.3]heptane-2-yl]methanone; [3-[6-(2-azaspiro[3.4]octane-2-yl)-3-pyridyl]azetidine-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]yl]heptane-2; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-[2-fluoro-4-(trifluoromethyl)phenyl]-2-azaspiro[3.3]heptane-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-yl]-[6-(4-mesylphenyl)-2-azaspiro[3.3]heptane-2-yl]methanone; [6-(5-cyclopropyl-4N-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(trifluoromethyl)phenyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[5-(trifluoromethyl)-2-pyridyl]oxymethyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[4-(trifluoromethyl)-2-pyridyl]oxymethyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-methoxy-5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[difluoro-[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-[1-(trifluoromethyl)cyclopropyl]-1N-pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[3-[1-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]-1-bicyclo[1.1.1]pentanyl]methyl]-5-(trifluoromethyl)-2-pyridone; 1-[[3-[1-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]azetidin-3-yl]-1-bicyclo[1.1.1]pentanyl]methyl]-4-(trifluoromethyl)-2-pyridone; [6-[3-(1-aminocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[4-(trifluoromethyl)pyrazol-1-yl]methyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethylsulfonimidoyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-triphenylpyrazol-1-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(methylsulfonimidoyl)-3-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-mesylpyrazol-1-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 5-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-3-(difluoromethyl)-2-pyridone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[3-(trifluoromethyl)isoxazol-5-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; 3-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(difluoromethyl)-2-pyridone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-methyl-5-(trifluoromethyl)-1,2,4-triazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-[1-(trifluoromethyl)cyclopropyl]-1,2,4-oxadiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)pyrazin-2-one; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(2,2,2-trifluoroethyl)triazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)-1,2,4-triazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(2,2,2-trifluoroethoxy)-3-pyridyl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-[1-(trifluoromethyl)cyclopropyl]imidazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-isopropoxy-5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(1S)-1-[4-methyl-5-(trifluoromethyl)-2-pyridyl]ethyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(1R)-1-[4-methyl-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(1-trifluorocyclopropyl)phenyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)-2-pyridyl]oxy]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]oxymethyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)triazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(3,3,3-trifluoropropyl)pyrazol-3-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-[(5-cyclopropylpyrazol-1-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [3-[3-[difluoro-[4-(trifluoromethyl)phenyl]methyl]-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]-[6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[3-(3-methyl-1H-pyrazol-5-yl)-1-bicyclo[1.1.1]pentanyl]azetidin-1-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[4-(methylsulfonimidoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-mesyl-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[2-[3-(trifluoromethyl)azetidin-1-yl]pyrimidin-5-yl]azetidin-1-yl]methanone; [4-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]piperazino]-(3-fluorophenyl)methanone; 4-[[1-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-4-piperidyl]oxymethyl]-2-methoxybenzamide; [3-[4-(2-chloro-4-mesylphenyl)phenyl]azetidin-1-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[2-fluoro-4-(trifluoromethyl)phenyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[[1-(trifluoromethyl)cyclopropyl]amino]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[4-mesyl-3-(trifluoromethyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3,5-difluoro-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1H-indazol-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)imidazo[1,2-a]pyridin-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)imidazo[1,5-a]pyridin-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1H-indazol-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone and [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone.

14. A compound of formula (I) according to claim 13 or a pharmaceutically acceptable salt thereof, selected from: [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)pyrimidin-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)pyrimidin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1H-pyrazol-5-yl]methyl]-2-azaspiro [3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-cyclopropyl-3-(trifluoromethyl)pyrazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-5-(trifluoromethyl)-2-pyridone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)triazol-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(4-trifluorobenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(4-trifluorobenzyl)-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-methyl-5-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[6-(trifluoromethyl)pyridazin-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[2-methyl-4-(trifluoromethyl)pyrazol-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-[3-(3,3-difluorocyclobutyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-(2-fluoro-4-trifluorobenzyl)oxyazetidin-1-yl]methanone; [6-[3-(1-hydroxycyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[5-[[1-(trifluoromethyl); 5-[[2-[6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-3-(trifluoromethyl)-2-cyanopyridine; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridyl] methyl]-2-azaspiro [3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[4-[3-(difluoromethyl)-5-methyl-1,2,4-triazol-1-yl]phenyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-[[5-(trifluoromethyl)isoxazol-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[7-(3-triflylbenzyl)-2,7-diazaspiro[3.4]octan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[3-[4-(trifluoromethylsulfonimidoyl)phenyl]azetidin-1-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-(trifluoromethyl)pyrimidin-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 4-[[2-[6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[5-(2,2-dimethylpropyl)-1,3,4-thiadiazol-2-yl]-1-bicyclo[1.1.1]-pentanyl]azetidin-1-yl]methanone; 5-[[2-[6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)benzonitrile; [6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-triphenylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1N-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-triflyl-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-(3-fluoro-5-triphenylbenzyl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[3-[3-[[5-(trifluoromethyl)pyrazin-2-yl]-amino]-1-bicyclo[1.1.1]-pentanyl]azetidin-1-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-[1-(trifluoromethyl)cyclopropyl]-pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[2-methyl-5-(trifluoromethyl)triazol-4-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1N-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-triflyl-3-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethylsulfonimidoyl)-2-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-[3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-[1-(trifluoromethyl); [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(5-trifluoromethyl-2-pyridyl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[difluoro-[6-(trifluoromethyl)-3-pyridyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; 5-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptane-6-yl]methyl]-2-(trifluoromethyl)nicotinonitrile; 5-[[2-[6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-2-(trifluoromethyl)isonicotinnitrile; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[fluoro-[6-(trifluoromethyl)pyridin-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(5-cyclopropyl-3-methylpyrazol-1-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[(3-cyclopropyl-5-methylpyrazol-1-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[2-fluoro-4-(trifluoromethylsulfonimidyoyl)benzyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-[3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-(4-trifluorobenzyl)-2,6-diazaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[4-(trifluoromethyl)pyrazol-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-(trifluoromethyl)-1,2,4-thiadiazol-5-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[difluoro-[5-(trifluoromethyl)pyrazin-2-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-[1-(trifluoromethyl)cyclopropyl]-1H-pyrazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[(4-trifluoropyrazol-1-yl)methyl]-2-azaspiro[3.3]heptan-2-yl]methanone; [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[3-[1-(trifluoromethyl)cyclopropyl]-1,2,4-oxadiazol-5-yl]methyl]-2,6-diazaspiro[3.3]heptan-2-yl]methanone; 1-[[2-[6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptane-2-carbonyl]-2-azaspiro[3.3]heptan-6-yl]methyl]-5-(trifluoromethyl)pyrazin-2-one and [6-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-2-azaspiro[3.3]heptan-2-yl]-[6-[[1-(2,2,2-trifluoroethyl)-1,2,4-triazol-3-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone.

15. A process for producing a compound of formula (I) according to any one of claims 1 to 14 or a pharmaceutically acceptable salt thereof, comprising reacting a compound of formula 2 where R 3 and R 4 are as defined in any of paragraphs 1-14, with a compound of formula 1 where R 3 and R 4are as defined in any one of paragraphs 1 to 14, by heating in a solvent such as DMF or CH3CN, in the presence of a base such as DIPEA, to form the said compound of formula (I).

16. A compound of formula (I) according to any one of claims 1 to 14 or a pharmaceutically acceptable salt thereof, obtained according to the method according to claim 15.

17. A compound of formula (I) according to any one of claims 1 to 14, or a pharmaceutically acceptable salt thereof, for use as a therapeutically active substance.

18. A pharmaceutical composition comprising a compound of formula (I) according to any one of claims 1-14 or a pharmaceutically acceptable salt thereof and a therapeutically inert carrier.

19. A method for treating or preventing neuroinflammation, neurodegenerative diseases, pain, cancer, mental disorders and / or inflammatory bowel disease in a mammal, said method comprising administering to said mammal a therapeutically effective amount of a compound of formula (I) according to any one of claims 1-14, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition according to claim 18.

20. The method according to claim 19, wherein said neuroinflammation, neurodegenerative diseases, pain, cancer and mental disorders are selected from multiple sclerosis, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, traumatic brain injury, neurotoxicity, stroke, epilepsy, anxiety, migraine, depression, hepatocellular carcinoma, colon carcinogenesis, ovarian cancer, neuropathic pain, chemotherapy-induced neuropathy, acute pain, chronic pain, spasticity associated with pain, abdominal pain, abdominal pain associated with irritable bowel syndrome and / or visceral pain.

21. A compound according to any one of claims 1-14, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition according to claim 18 for use in the method according to claim 19 or 20.

22. Use of a compound according to any one of claims 1-14 or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition according to claim 18 in the method according to claim 20 or 21.

23. Use of a compound according to any one of claims 1-14 or a pharmaceutically acceptable salt thereof for the preparation of a medicinal product for use in the method according to claim 20 or 21.