Blood vessel prosthesis for regenerative medicine

A vascular implant using natural mulberry silk threads and glutaraldehyde-treated gelatin addresses biocompatibility and endothelialization issues, ensuring stable operation and tissue integration with enhanced mechanical properties.

RU244414U1Active Publication Date: 2026-06-30FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE NATSIONALNYJ MEDITSINSKIJ ISSLEDOVATELSKIJ TSENTR TRANSPLANTOLOGII I ISKUSSTVENNYKH ORGANOV IMENI AKADKA V I SHUMAKOVA MINISTSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII FGBU NMITS TIO IM AK V I SHUMAKOVA MINZDRAVA ROSSII
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Patent Information

Authority / Receiving Office
RU · RU
Patent Type
Utility models
Current Assignee / Owner
FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE NATSIONALNYJ MEDITSINSKIJ ISSLEDOVATELSKIJ TSENTR TRANSPLANTOLOGII I ISKUSSTVENNYKH ORGANOV IMENI AKADKA V I SHUMAKOVA MINISTSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII FGBU NMITS TIO IM AK V I SHUMAKOVA MINZDRAVA ROSSII
Filing Date
2026-02-20
Publication Date
2026-06-30

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Abstract

This utility model relates to the field of medicine, specifically to vascular surgery and tissue engineering, and can be used for the replacement, reconstruction, or bypass of blood vessels. A blood vessel prosthesis for regenerative medicine comprises a tubular cylindrical body and a cylindrical base woven from threads. The cylindrical body is made of gelatin treated with a 2.5% glutaraldehyde solution. The body has an internal diameter of 1.0 to 9.0 mm and a wall thickness of 0.5 to 1.0 mm. The cylindrical base is woven from natural silk threads of mulberry silk with a diameter of 10 to 50 μm and is located in the wall of the cylindrical body as a reinforcing element. The technical result is to ensure the stable operation of a small-diameter (1.0 to 9.0 mm) vascular implant by creating conditions for accelerated endothelialization and tissue integration. 4 ill., 2 pr.
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