Composition of complete dietary food for dogs with exocrine pancreatic insufficiency

A specially formulated dietary food for dogs with exocrine pancreatic insufficiency addresses the lack of gastrointestinal benefits in existing feeds by normalizing intestinal microflora and enhancing digestive health through a balanced ingredient composition, achieving improved digestive health and clinical efficacy.

RU2864968C2Active Publication Date: 2026-06-30OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTYU TOMILE
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Patent Information

Authority / Receiving Office
RU · RU
Patent Type
Patents
Current Assignee / Owner
OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTYU TOMILE
Filing Date
2024-05-20
Publication Date
2026-06-30

AI Technical Summary

Technical Problem

Existing veterinary feed compositions for dogs and cats with exocrine pancreatic insufficiency lack a pronounced positive effect on the gastrointestinal tract and pancreas, and there is a need for a therapeutic diet that can improve digestive health and normalize intestinal microflora.

Method used

A complete dietary food for dogs with exocrine pancreatic insufficiency is formulated with specific ratios of ingredients including grain, protein, mineral, vitamin, and fiber sources, along with a flavor enhancer and oils, designed to be easily digestible and contain a complex of fermentable and non-fermentable dietary fibers, humic and fulvic acids, and antioxidants, promoting gastrointestinal health.

Benefits of technology

The food composition effectively normalizes intestinal microflora, reduces opportunistic microorganisms, increases beneficial bacteria, and enhances digestive health, providing clinical effectiveness and ease of use.

✦ Generated by Eureka AI based on patent content.

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Abstract

FIELD: veterinary medicine and dietetics.SUBSTANCE: development of complete feed compositions that can provide a therapeutic effect in cases of exocrine pancreatic insufficiency. A composition of dry complete dietary food for dogs with exocrine pancreatic insufficiency has been developed. It consists of easily digestible ingredients and it includes the following components in the following ratio, wt.%: grain part: mixture of rice, wheat, hulled barley and corn – 55.0–56.0; protein part of plant origin: isolated soy protein, beet pulp, wheat bran, flax seeds – 10.0; protein part of animal origin: feather meal, chicken liver, egg powder – 20.0; mineral supplement: feed chalk, monocalcium phosphate, table salt – 2.0; vitamin premix: A, D3, E, K, B1, В2, В3, В5, Вб, В12, Вс, H – 2.5; flavor enhancer in the form of enzymatic hydrolysate of pork and chicken by-products – 3–3.5; brewer's yeast – 2.5–3.0; mixture of fish and chicken fat – 3.0–5.0.EFFECT: obtain a composition of dry complete dietary food for dogs with exocrine pancreatic insufficiency, which is easily reproducible, effective from a clinical point of view, and also convenient in dosing and use.1 cl, 3 tbl, 1 ex
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Description

[0001] The invention relates to veterinary medicine and dietetics, namely to the development of complete feed compositions that can provide a therapeutic effect in exocrine pancreatic insufficiency.

[0002] Today, digestive system pathologies account for 35% of all non-communicable diseases. Gastrointestinal diseases are among the most common illnesses in dogs and cats today, accounting for approximately 25% of all visits to veterinary clinics. One of the most promising methods for the prevention and treatment of such pathologies is diet therapy.

[0003] The composition of sheep feed (SU670293) is known to prevent obesity in these animals. A drawback of this composition is the lack of a pronounced positive effect on the gastrointestinal tract in general and the pancreas in particular.

[0004] A dry kibble food for dogs (BY12952C1) is also well-known, allowing them to fully meet their physiological needs. A drawback of this formula is the lack of a pronounced positive effect on the gastrointestinal tract in general, and the pancreas in particular.

[0005] The technical result is a solution to the problem of creating a complete dietary food for dogs with exocrine pancreatic insufficiency. The advantages of this composition include its ease of reproducibility, clinical effectiveness, and ease of dosing and use.

[0006] To achieve the technical result, the compositions of a complete dietary food for dogs with exocrine pancreatic insufficiency are proposed in the following ratio, mass %:

[0007] 1) For dry complete feed:

[0008] - grain part (mixture of rice, wheat, hulled barley and corn) - 55.0-56.0;

[0009] - protein part of plant origin (isolated soy protein, beet pulp, wheat bran, flax seeds) - 10.0;

[0010] - protein part of animal origin (feather meal, chicken liver, egg powder) -20.0;

[0011] - mineral supplement (feed chalk, monocalcium phosphate, table salt, plantain seeds Plantago psyllium, mannanoligasaccharides with beta-glucans and lutein) - 2.0;

[0012] - vitamin premix (A, D3, E, K, B1, B2, B3, B5B6, B 12 , B с , H, taurine, inulin, beech lignocellulose, complex of natural fulvic and humic acids) -2.5;

[0013] - flavor enhancer in the form of enzymatic hydrolysate of pork and chicken by-products -3-3.5;

[0014] - brewer's yeast - 2.5-3.0;

[0015] - a mixture of fish and chicken oil - 3.0-5.0.

[0016] 2) For canned complete feed:

[0017] - meat and animal products (chicken, egg mixture) - 34.0;

[0018] - plant components and their processed products (carrots, wheat flour, corn starch, beet fiber, wheat fiber, flaxseed flour) - 11.0;

[0019] - vitamins and minerals (vitamin-mineral premix, table salt, dextrose, vitamin C, tripolyphosphate) - 0.6;

[0020] - fats and oils (fish oil, sunflower oil) - 0.2;

[0021] - amino acids (taurine) - 0.2;

[0022] - thickeners - 0.2;

[0023] - water - 53.8.

[0024] Thus, the food consists of easily digestible ingredients, is low in fat, and contains the necessary levels of sodium and potassium. It uses specialized protein and carbohydrate sources, which reduce the risk of adverse reactions to the product. The food contains a complex of fermentable (prebiotic) and non-fermentable dietary fiber, as well as a postbiotic, which helps normalize the gastrointestinal microflora and improve the animal's health.

[0025] The use of specialized dietary food for gastrointestinal diseases is an important adjunct to treatment. These food formulations provide the following benefits:

[0026] - Easily digestible feed (protein digestibility 88.4%)

[0027] - Moderate energy content and reduced fat levels for weight control and reduced digestive burden

[0028] - Contains a complex of fermentable (prebiotics) and non-fermentable dietary fibers to normalize the microflora of the gastrointestinal tract and strengthen its health

[0029] - Humic and fulvic acids (postbiotic) increase the body's natural resistance, exhibit a positive therapeutic effect, activate digestion, improve the absorption of nutrients and minerals in feed, have strong antioxidant activity, protect the liver from damage, are a powerful natural electrolyte, and are characterized by antitoxic properties.

[0030] - Acceptable electrolyte levels

[0031] - High palatability of feed

[0032] - Optimal level of Omega-3 / Omega-6 unsaturated fatty acids

[0033] - High level of B vitamins

[0034] - Organic form of microelements

[0035] To obtain dry food, the following steps are implemented:

[0036] 1. The barley is peeling.

[0037] 2. The grain mixture is weighed and ground: rice, wheat, barley without films, corn.

[0038] 3. Weigh and mix the following ingredients: ground grain mixture, isolated soy protein, wheat gluten (for cats), wheat bran, sugar beet pulp, flaxseed, egg powder, brewer's yeast, mineral sources of calcium and phosphorus, table salt, animal / poultry meal.

[0039] 4. The above mixture is crushed.

[0040] 5. After grinding, a vitamin and mineral premix is ​​added to the mixture, after which everything is thoroughly mixed.

[0041] The premix is ​​ready for the next technological process.

[0042] 6. Chicken liver is weighed, ground into minced meat and prepared into an emulsion by adding water.

[0043] 7. Liquid chicken fat is weighed and a natural antioxidant based on rosemary is added to it.

[0044] 8. Premix, liver emulsion and fish oil are introduced into the extruder.

[0045] 9. After extrusion, thanks to the properties of the premix, the technical characteristics of the extruder, and the help of the die and knife, the feed acquires a specific texture, shape, and size of granules.

[0046] 10. The feed granules are dried.

[0047] 11. Dry granules are placed in a vacuum sprayer, where they are sprayed with liquid chicken fat and enzymatic hydrolysate of pork and chicken by-products.

[0048] 12. The granules are cooling.

[0049] 13. Food packaging

[0050] To obtain canned food, the following steps are implemented:

[0051] 1. Raw material preparation:

[0052] - Weighing of meat raw materials.

[0053] - Grinding of meat raw materials.

[0054] - Dosing dry ingredients.

[0055] 2. Preparing the minced meat mixture using a mixer:

[0056] - Mixing minced meat with dry ingredients.

[0057] - Second fine grinding on an emulsifier after mixing with dry ingredients.

[0058] - Pumping minced meat / emulsion into a storage tank for feeding to the steam tunnel.

[0059] 3. Forming pieces:

[0060] - Feeding minced meat / emulsion through the extruder heads onto the belt (conveyor) of the steam tunnel.

[0061] - Cutting steamed strips of minced meat / emulsion into pieces.

[0062] - The pieces enter the buffer tank for mixing with the sauce before feeding to the packaging machine.

[0063] 4. Making sauce / jelly:

[0064] - Mixing cold water and dry ingredients in a saucepan.

[0065] - Pumping sauce into a buffer tank to mix with the pieces before feeding to the packaging machine.

[0066] 5. Packing pieces and sauce into individual (primary) packaging.

[0067] 6. Sealing of products (sealing).

[0068] 7. Autoclaving of products (sterilization).

[0069] 8. Packing products into group packaging.

[0070] The daily feeding rate may vary depending on the age, activity, condition and living conditions of the animal (tables 1, 2).

[0071]

[0072] The essence of the invention is explained by the following example.

[0073] Animals for the study were selected using the pair-analogue method, all animals were sterilized, vaccinated according to the vaccination schedule, and the animals were previously subjected to helminthological examinations.

[0074] Group formation: 3 experimental groups of 10 animals each:

[0075] - experimental group 1 - mongrel dogs with gastrointestinal diseases of various etiologies (with damage to the pancreas), which are given a dry and canned form of a veterinary diet based on the above-described food.

[0076] - experimental group 2 - mongrel dogs with gastrointestinal diseases of various etiologies (with damage to the pancreas), which are given a dry form of a veterinary diet based on the above-described food.

[0077] - experimental group 3 - mongrel dogs with gastrointestinal diseases of various etiologies (with damage to the pancreas), which were given a diet.

[0078] Three times during the study, bio-samples from dogs were studied (before the start of feeding; one month after the start of feeding, 3 months after the start of feeding)

[0079] The study of the microflora of the rectal contents of dogs included sowing the test material on selective nutrient media with subsequent determination of the quantity and composition of microflora, namely Bifidobacterium spp. (Bifidobacteria), Lactobacillus spp. (Lactobacilli), E. coli with normal enzymatic activity, E. coli with weakly expressed enzymatic properties, lactose-negative E. coli, hemolytic E. coli, Enterococcus spp. (Enterococci), Proteus spp. (Microbes of the genus Proteus), Klebsiella spp. (Klebsiella), Enterobacter spp. (Enterobacter), Staphylococcus aureus (Staphylococcus aureus), S. epidermidis (Staphylococcus epidermidis), S. saprophyticus (Staphylococcus saprophyticus), Candida fungi, Non-fermenting gram-negative bacteria, Clostridium spp. (Clostridium), Clostridium difficile, Pseudomonas spp. (Pseudomonas aeruginosa). The results of the studies are presented in Table 3.

[0080]

[0081] In the study, before the administration of a veterinary diet, the number of Escherichia coli with normal enzymatic activity was significantly reduced in all groups by 10 ∧ 4 CFU / g in all study groups. Escherichia coli with hemolytic activity in the amount of 10 was isolated. ∧ 3 CFU / g in each of the study groups. Clostridium perfringens were isolated in an amount of 10 ∧ 3 CFU / g.

[0082] After using the veterinary diet in the control group, the number of Escherichia coli with normal enzymatic activity was significantly reduced to 10 ∧ 4 CFU / g. Fungi of the genus Candida were detected in the amount of 10 ∧ 4 CFU / g.

[0083] When taking the prescribed feed in a group of animals consuming dry food, in one of the samples the level of Bifidobacterium spp. was significantly reduced in the amount of 10 ∧ 6 CFU / g and Escherichia coli with normal enzymatic activity up to 10 ∧ 2 CFU / g.

[0084] When taking the prescribed food in the group of animals consuming dry and wet food, the number of Bifidobacterium spp. increased to 10 ∧ 9 CFU / g and Lactobacillus spp. Up to 10 ∧ 8 CFU / g. No pathogenic microflora were detected.

[0085] Thus, the veterinary diet used has a positive effect on the intestinal microflora: the number of opportunistic microorganisms has decreased or is absent in most animal samples compared to studies before the use of the diet.

[0086] The beneficial effect also consists of an increase in the number of "beneficial" microorganisms after the use of a veterinary diet, namely, in the group of dogs consuming dry and wet food in the diet - bifidobacteria and lactobacilli, which ensure the breakdown and digestion of food, the absorption of iron, the neutralization of toxins, absorb bile acids, bile pigments, cholesterol; stimulate intestinal peristalsis, preventing disorders (diarrhea and delayed evacuation), activate lymphoid tissue, providing innate immunity mechanisms, which positively affects, among other things, the condition of the pancreas.

Claims

The composition of dry complete dietary food for dogs with exocrine pancreatic insufficiency, consisting of easily digestible ingredients, characterized in that it includes the following components in the following ratio, mass %: - grain part: a mixture of rice, wheat, hulled barley and corn - 55.0-56.0; - protein part of plant origin: isolated soy protein, beet pulp, wheat bran, flax seeds - 10.0; - protein part of animal origin: feather meal, chicken liver, egg powder -20.0; - mineral supplement: feed chalk, monocalcium phosphate, table salt - 2.0; - vitamin premix: A, D3, E, K, B1, B2, B3, B5, B б , IN 12 , IN с , H - 2.5; - flavor enhancer in the form of enzymatic hydrolysate of pork and chicken by-products - 3-3.5; - brewer's yeast - 2.5-3.0; - a mixture of fish and chicken oil - 3.0-5.0.