Pharmaceutical composition of 1-[2-(1-methylimidazol-4-yl)ethyl]perhydroazine-2,6-dione

Abstract

FIELD: chemical-pharmaceutical industry.SUBSTANCE: pharmaceutical composition in powder form and medicinal product containing 1-[2-(1-methylimidazol-4-yl)ethyl]perhydroazine-2,6-dione or its pharmaceutically acceptable salt. A pharmaceutical composition in powder form with antiviral activity, containing 1-[2-(1-methylimidazol-4-yl)ethyl]perhydroazine-2,6-dione or a pharmaceutically acceptable salt thereof in an amount of 0.5–10.0 wt.% and excipients including one or more fillers selected from mannitol, maltodextrin or a mixture thereof, in an amount of 85.0–99.0 wt.% and a sweetener in an amount of 0.1–5.0 wt.%, as well as a medicinal product in powder form for the preparation of a solution for the treatment and / or prevention of viral respiratory diseases, containing the above pharmaceutical composition.EFFECT: high stability, low hygroscopicity, good flowability and mixing homogeneity, as well as hypoallergenicity and the possibility of use in pediatrics.13 cl, 4 tbl, 3 ex

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