Molecules that are beneficial in insect control, and intermediates, components, and processes related to them.

Abstract

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Description

Molecules having pestlcidal utility, and intermediates, compositions, and processes, related theretoCross-references to related applicationsThis Application claims the benefit of, and priority from, U .S. provisional applications serial numbers 62 / 148830; 62 / 148837; 62 / 148809 ; 62 / 148814;62 / 148818; and 62 / 148824; all of which were filed on April 17, 2015. The entire contents of all of the above-identified applications are hereby incorporated by reference into this Application.Field of this disclosureThis disclosure relates to the field of molecules having pesticida l utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides.Background of this disclosure"Many of the most dangerous human diseases are transmitted by insect vectors" (Rivero et al. ). "Historically, malaria, dengue, yellow fever, plague, filariasis, louse- borne typhus, trypanomiasis, leishmaniasis, and other vector borne diseases were responsible for more human disease and death in the 17ththrough the early 20* centuries than all other causes combined" (Gubler) . Vector-borne diseases are responsible for about 17% of the global parasitic and infectious diseases. Malaria alone causes over 800,000 deaths a year, 85% of which occur in children under five years of age. Each year there are about 50 to about 100 million cases of dengue fever. A further 250,000 to 500,000 cases of dengue hemorrhagic fever occur each year (Matthews) . Vector control plays a critical role in the prevention and control of infectious diseases. However, insecticide resistance, including resistance to multiple insecticides, has arisen in all insect species that are major vectors of human diseases (Rivero et al . ) . Recently, more than 550 arthropod species have developed resistance to at least one pesticide (Whalon et al . ) . Furthermore, the cases of insect resistance continue to exceed by far the number of cases of herbicide and fungicide resistance (Sparks et al. ).Each year insects, plant pathogens, and weeds, destroy more than 40% of all food production. This loss occurs despite the application of pesticides and the use of a wide array of non-chemical controls, such as, crop rotations, and biological controls. If just some of this food could be saved, it could be used to feed the more than three billion people in the world who are malnourished (Pimental ).Plant parasitic nematodes are among the most widespread pests, and are frequently one of the most insidious and costly. It has been estimated that lossesattributable to nematodes are from about 9% in developed countries to about 15% in undeveloped countries. However, in the United States of America a survey of 35 States on various crops indicated nematode-derived losses of up to 25% (N icol et al . ) .It is noted that gastropods (slugs and snails) are pests of less economic importance than other arthropods or nematodes, but in certain places, they may reduce yields substantially, severely affecting the quality of harvested products, as well as, transmitting human, animal, and plant diseases. While only a few dozen species of gastropods are serious regional pests, a handful of species are important pests on a worldwide scale. In particular, gastropods affect a wide variety of agricultural and horticultural crops, such as, arable, pastoral, and fiber crops; vegetables; bush and tree fruits; herbs; and ornamentals (Speiser).Termites cause damage to all types of private and public structures, as well as to agricultural and forestry resources. In 2005, it was estimated that termites cause over US$50 billion in damage worldwide each year (Korb).Consequently, for many reasons, including those mentioned above, there is an on-going need for the costly (estimated to be about US$256 million per pesticide in 2010), time-consuming (on average about 10 years per pesticide), and difficult, development of new pesticides (CropLife America).Certain references cited in this disclosureCropLife America, The Cost of New Agrochemical Product Discovery, Development& Registration, and Research & Development predictions for the Future, 2010.Drewes, M . , Tietjen, K., Sparks, T.C. , High-Throughput Screening inAgrochemical Research, Modern Methods in Crop Protection Research, Part I, Methods for the Design and Optimization of New Active Ingredients, Edited by Jeschke, P. , Kramer, W., Schirmer, U ., and Matthias W., p. 1 -20, 2012.Gubler, D., Resurgent Vector-Borne Diseases as a Global Health Problem, Emerging Infectious Diseases, Vol. 4, No. 3, p. 442-450, 1998.Korb, J . , Termites, Current Biology, Vol . 17, No. 23, 2007.Matthews, G., Integrated Vector Management: Controlling Vectors of Malaria and Other Insect Vector Borne Diseases, Ch. 1, p. 1 , 2011.Nicol, J ., Turner S. , Coyne, L , den N ijs, L, Hocksland, L , Tahna-Maafi, Z., Current Nematode Threats to World Agriculture, Genomic and Molecular Genetics of Plant - Nematode Interactions, p. 21-43, 2011.Pimental, D. , Pest Control in World Agriculture, Agricultural Sciences - Vol . II, 2009.Rivero, A., Vezilier, J ., Weill, M. , Read, A., Gandon, S. , Insect Control of Vector- Borne Diseases : When is Insect Resistance a Problem? Public Library of SciencePathogens, Vol. 6, No. 8, p. 1-9, 2010.Sparks T.C ., Nauen R. , IRAC : Mode of action classification and insecticide resistance management, Pesticide Biochemistry and Physiology (2014) available online 4 December 2014.Speiser, B. , Molluscicides, Encyclopedia of Pest Management, Ch. 219, p. 506- 508, 2002.Whalon, M ., Mota-Sanchez, D. , Hollingworth, R., Analysis of Global Pesticide Resistance in Arthropods, Global Pesticide Resistance in Arthropods, Ch. 1, p. 5-33, 2008.Definitions used in this disclosureThe examples given in these definitions are generally non-exhaustive and must not be construed as limiting this disclosure. It is understood that a substituent should comply with chemical bonding rules and steric compatibility constraints in relation to the particular molecule to which it is attached . These definitions are only to be used for the purposes of this disclosure.The phrase "active ingredient" means a material having activity useful in controlling pests, and / or that is useful in helping other materials have better activity in controlling pests, examples of such materials include, but are not limited to, acaricides, algicides, antifeedants, avicides, bactericides, bird repellents, chemosterilants, fungicides, herbicide safeners, herbicides, insect attractants, insect repellents, insecticides, mammal repellents, mating disrupters, molluscicides, nematicides, plant activators, plant growth regulators, rodenticides, synergists, and virucides (see alanwood. net) . Specific examples of such materials include, but are not limited to, the materials listed in active ingredient group alpha .The phrase "active ingredient group alpha" (hereafter "AIGA") means collectively the following materials :( 1 ) (3-ethoxypropyl)mercury bromide, 1,2-dibromoethane, 1,2- dichloroetha ne, 1,2-dichloropropane, 1,3-dichloropropene, 1-MCP, 1- methylcyclopropene, 1-naphthol, 2-(octylthio)ethanol, 2,3,3-TPA, 2,3,5-tri-iodobenzoic acid, 2,3,6-TBA, 2,4,5-T, 2,4, 5-TB, 2,4,5-TP, 2,4-D, 2,4-DB, 2,4-DEB, 2,4-DEP, 2,4- DES, 2,4-DP, 2,4-MCPA, 2,4-MCPB, 2iP, 2-methoxyethylmercury chloride, 2- phenylphenol, 3,4-DA, 3,4-DB, 3,4-DP, 3,6-dichloropicolinic acid, 4-a minopyridine, 4- CPA, 4-CPB, 4-CPP, 4- hydroxyphenethyl alcohol, 8-hydroxyquinoline sulfate, 8- phenylmercurioxyquinoline, abamectin, abamectin-aminomethyl, abscisic acid, ACC, acephate, acequinocyl, acetamiprid, acethion, acetochlor, acetofenate, acetophos, acetoprole, acibenzolar, acifluorfen, aclonifen, ACN, acrep, acrinathrin, acrolein, acrylonitrile, acypetacs, afidopyropen, afoxolaner, alachlor, alanap, alanycarb, albendazole, aldicarb, aldicarb sulfone, aldimorph, aldoxycarb, aldrin, allethrin, allicin, allidochlor, allosamidin, alloxydim, allyl alcohol, allyxycarb, alorac, a / pfta-cypermethrin,a / p / 73-endosulfan, alphamethrin, altretamine, aluminium phosphide, aluminum phosphide, ametoctradin, ametridione, ametr n, ametryne, amibuzin, amicarbazone, amicarthiazol, amidithion, amidoflumet, amidosulfuron, aminocarb, aminocyclopyrachlor, aminopyralid, aminotriazole, amiprofos-methyl, amiprophos, amiprophos-methyl, amisulbrom, amiton, amitraz, amitrole, ammonium sulfamate, amobam, amorphous silica gel, amorphous silicon dioxide, ampropylfos, AMS, anabasine, ancymidol, anilazine, anilofos, anisuron, anthraquinone, antu, apholate, aramite, arprocarb, arsenous oxide, asomate, aspirin, asulam, athidathion, atraton, atrazine, aureofungin, avermectin Bl , AVG, aviglycine, azaconazole, azadirachtin, azafenidin, azamethiphos, azidithion, azimsulfuron, azinphosethyl, azinphos-ethyl, azinphosmethyl, azinphos- methyl, aziprotryn, aziprotryne, azithiram, azobenzene, azocyclotin, azothoate, azoxystrobin, bachmedesh, barban, barbanate, barium hexafluorosilicate, barium polysulfide, barium silicofluoride, barthrin, basic copper carbonate, basic copper chloride, basic copper sulfate, BCPC, beflubutamid, benalaxyl, benalaxyl-M, benazolin, bencarbazone, benclothiaz, bendaqingbingzhi, bendiocarb, bendioxide, benefin, benfluralin,benfuracarb, benfuresate, benmihuangcaoan, benodanil, benomyl, benoxacor, benoxafos, benquinox, bensulfuron, bensulide, bensultap, bentaluron, bentazon, bentazone, benthiavalicarb, benthiazole, benthiocarb, bentranil, benzadox, benzalkonium chloride, benzamacril, benzamizole, benzamorf, benzene hexachloride, benzfendizone, benzimine, benzipram, benzobicyclon, benzoepin, benzofenap, benzofluor,benzohydroxamic acid, benzomate, benzophosphate, benzothiadiazole, benzovindiflupyr, benzoximate, benzoylprop, benzthiazuron, benzuocaotong, benzyl benzoate,benzyladenine, berberine, beta-cyfluthrin, beta-cypermethrin, bethoxazin, BHC, bialaphos, bicyclopyrone, bifenazate, bifenox, bifenthrin, bifuj unzhi, bilanafos, binapacryl, bingqingxiao, bioallethrin, bioethanomethrin, biopermethrin, bioresmethrin, biphenyl, bisazir, bismerthiazol, bismerthiazol-copper, bisphenylmercury methylenedi(x- naphthalene-y-sulphonate), bispyribac, bistrifluron, bisultap, bitertanol, bithionol, bixafen, blasticidin-S, borax, Bordeaux mixture, boric acid, boscalid, BPPS, brassinolide, brassinolide-ethyl, brevicomin, brodifacoum, brofenprox, brofenvalerate, broflanilide, brofluthrinate, bromacil, bromadiolone, bromchlophos, bromethalin, bromethrin, bromfenvinfos, bromoacetamide, bromobonil, bromobutide, bromociclen, bromocyclen, bromo-DDT, bromofenoxim, bromofos, bromomethane, bromophos, bromophos-ethyl, bromopropylate, bromothalonil, bromoxynil, brompyrazon, bromuconazole, bronopol, BRP, BTH, bucarpolate, bufencarb, buminafos, bupirimate, buprofezin, Burgundy mixture, busulfan, busulphan, butacarb, butachlor, butafenacil, butam, butamifos, butane-fipronil, butathiofos, butenachlor, butene-fipronil, butethrin, buthidazole, buthiobate, buthiuron, butifos, butocarboxim, butonate, butopyronoxyl, butoxycarboxim, butralin, butrizol, butroxydim, buturon, butylamine, butylate, butylchlorophos, butylene-fipronil, cacodylic acid, cadusafos, cafenstrole, calciferol, calcium arsenate, calcium chlorate, calcium cyanamide, calcium cyanide, calcium polysulfide, calvinphos, cambendichlor, camphechlor, camphor, captafol, captan, carbarn, carbamorph, carbanolate, carbaril, carbaryl, carbasulam, carbathion, carbendazim, carbendazol, carbetamide, carbofenotion, carbofuran, carbon disulfide, carbon tetrachloride, carbonyl sulfide, carbophenothion, carbophos, carbosulfan, carboxazole, carboxide, carboxin, carfentrazone, carpropamid, cartap, carvacrol, carvone, CAVP, CDAA, CDEA, CDEC, cellocidin, CEPC, ceralure, cerenox, cevadilla, Cheshunt mixture, chinalphos, chinalphos- methyl, chinomethionat, chinomethionate, chiralaxyl, chitosan, chlobenthiazone, chlomethoxyfen, chloralose, chloramben, chloramine phosphorus, chloramphenicol, chloraniformethan, chloranil, chloranocryl, chlorantraniliprole, chlorazifop, chlorazine, chlorbenside, chlorbenzuron, chlorbicyclen, chlorbromuron, chlorbufam, chlordane, chlordecone, chlordimeform, chlorempenthrin, chloretazate, chlorethephon,chlorethoxyfos, chloreturon, chlorfenac, chlorfenapyr, chlorfenazole, chlorfenethol, chlorfenidim, chlorfenprop, chlorfenson, chlorfensulphide, chlorfenvinphos,chlorfenvinphos-methyl, chlorfluazuron, chlorflurazole, chlorflurecol, chlorfluren, chlorflurenol, chloridazon, chlorimuron, chlorinate, chlor-IPC, chlormephos, chlormequat, chlormesulone, chlormethoxynil, chlornidine, chlornitrofen, chloroacetic acid,chlorobenzilate, chlorodinitronaphthalenes, chlorofenizon, chloroform, chloromebuform, chloromethiuron, chloroneb, chlorophacinone, chlorophos, chloropicrin, chloropon, chloropropylate, chlorothalonil, chlorotoluron, chloroxifenidim, chloroxuron, chloroxynil, chlorphonium, chlorphoxim, chlorprazophos, chlorprocarb, chlorpropham, chlorpyrifos, chlorpyrifos-methyl, chlorquinox, chlorsulfuron, chlorthal, chlorthiamid, chlorthiophos, chlortoluron, chlozolinate, chitosan, cholecalciferol, choline chloride, chromafenozide, cicloheximide, cimectacarb, cimetacarb, cinerin I, cinerin II, cinerins, cinidon-ethyl, cinmethylin, cinosulfuron, cintofen, ciobutide, cisanilide, cismethrin, clacyfos, clefoxydim, clenpirin, clenpyrin, clethodim, climbazole, cliodinate, clodinafop, cloethocarb, clofencet, clofenotane, clofentezine, clofenvinfos, clofibric acid, clofop, clomazone, clomeprop, clonitralid, cloprop, cloproxydim, clopyralid, cloquintocet, cloransulam, closantel, clothianidin, clotrimazole, cloxyfonac, cloxylacon, clozylacon, CMA, CMMP, CMP, CMU, codlelure, colecalciferol, colophonate, copper 8-quinolinolate, copper acetate, copper acetoarsenite, copper arsenate, copper carbonate, basic, copper hydroxide, copper naphthenate, copper oleate, copper oxychloride, copper silicate, copper sulfate, copper sulfate, basic, copper zinc chromate, coumachlor, coumafene, coumafos, coumafuryl, coumaphos, coumatetralyl, coumethoxystrobin, coumithoate, coumoxystrobin, CPMC, CPMF, CPPC, credazine, cresol, cresylic acid, crimidine, crotamiton, crotoxyfos, crotoxyphos, crufomate, cryolite, cue-lure, cufraneb, cumyleron, cumyluron, cuprobam, cuprous oxide, curcumenol, CVMP, cyanamide, cyanatryn, cyanazine, cyanofenphos,cyanogen, cyanophos, cyanthoate, cyantraniliprole, cyanuric acid, cyazofamid, cybutryne, cyclafuramid, cyclanilide, cyclaniliprole, cyclethrin, cycloate, cycloheximide, cycloprate, cycloprothrin, cyclopyrimorate, cyclosulfamuron, cycloxydim, cycluron, cyenopyrafen, cyflufenamid, cyflumetofen, cyfluthrin, cyhalofop, cyhalothrin, cyhexatin, cymiazole, cymoxanil, cyometrinil, cypendazole, cypermethrin, cyperquat, cyphenothrin, cyprazine, cyprazole, cyproconazole, cyprodinil, cyprofuram, cypromid, cyprosulfamide, cyromazine, cythioate, cytrex, daimuron, dalapon, daminozide, dayoutong, dazomet, DBCP, d-camphor, DCB, DCIP, DCPA, DCPTA, DCU, DDD, DDPP, DDT, DDVP, debacarb, decafentin, decamethrin, decarbofuran, deet, dehydroacetic acid, deiquat, delachlor, delnav, deltamethrin, demephion, demephion-O, demephion-S, demeton, demeton- methyl, demeton-O, demeton-O-methyl, demeton-S, demeton-S-methyl, demeton-S- methyl sulphone, demeton-S-methylsulphon, DEP, depallethrine, derris, desmedipham, desmetryn, desmetryne, d-fanshiluquebingj uzhi, diafenthiuron, dialifor, dialifos, diallate, diamidafos, dianat, diatomaceous earth, diatomite, diazinon, dibrom, dibutyl phthalate, dibutyl succinate, dicamba, dicapthon, dichlobenil, dichlofenthion, dichlofluanid, dichlone, dichloralurea, dichlorbenzuron, dichlorfenidim, dichlorflurecol, dichlorflurenol, dichlormate, dichlormid, dichloromethane, dicloromezotiaz, dichlorophen, dichlorprop, dichlorprop-P, dichlorvos, dichlozolin, dichlozoline, diclobutrazol, diclocymet, diclofop, diclomezine, dicloran, diclosulam, dicofol, dicopha ne, dicoumarol, dicresyl, dicrotophos, dicryl, dicumarol, dicyclanil, dicyclonon, dieldrin, dienochlor, diethamquat, diethatyl, diethion, diethion, diethofencarb, dietholate, diethon, diethyl pyrocarbonate,diethyltoluamide, difenacoum, difenoconazole, difenopenten, difenoxuron, difenzoquat, difethia lone, diflovidazin, diflubenzuron, diflufenican, diflufenicanil, diflufenzopyr, diflumetorim, dikegulac, dilor, dimatif, dimefluthrin, dimefox, dimefuron, dimehypo, dimepiperate, dimetachlone, dimetan, dimethacarb, dimethachlone, dimethachlor, dimethametryn, dimethenamid, dimethenamid-P, dimethipin, dimethirimol, dimethoate, dimethomorph, dimethrin, dimethyl carbate, dimethyl disulfide, dimethyl phthalate, dimethylvinphos, dimetilan, dimexano, dimidazon, dimoxystrobin, dimpylate, dimuron, dinex, dingj unezuo, diniconazole, diniconazole-M, dinitramine, dinitrophenols, dinobuton, dinocap, dinocap-4, dinocap-6, dinocton, dinofenate, dinopenton, dinoprop, dinosam, dinoseb, dinosulfon, dinotefuran, dinoterb, dinoterbon, diofenolan,dioxabenzofos, dioxacarb, dioxathion, dioxation, diphacin, diphacinone, diphenadione, diphenamid, diphenamide, diphenyl sulfone, diphenylamine, diphenylsulphide, diprogulic acid, dipropalin, dipropetryn, dipterex, dipymetitrone, dipyrithione, diquat, disodium tetraborate, disosultap, disparlure, disugran, disul, disulfiram, disulfoton, ditalimfos, dithianon, dithicrofos, dithioether, dithiometon, dithiopyr, diuron, dixanthogen, d- limonene, DMDS, DMPA, DNOC, dodemorph, dodicin, dodine, dofenapyn, doguadine, dominicalure, doramectin, DPC, drazoxolon, DSMA, cZ-frans-allethrin, d-trans-resmethrin, dufulin, dymron, EBEP, EBP, ebufos, ecdysterone, echlomezol, EDB, EDC, EDDP, edifenphos, eglinazine, emamectin, EMPC, empenthrin, enadenine, endosulfan, endothal, endothall, endothion, endrin, enestroburin, enilconazole, enoxastrobin, ephirsulfonate, EPN, epocholeone, epofenonane, epoxiconazole, eprinomectin, epronaz, EPTC, erbon, ergocalciferol, erluj ixiancaoan, esdepallethrine, esfenvalerate, ESP, esprocarb, etacelasil, etaconazole, etaphos, etem, ethaboxam, ethachlor, ethalfluralin, ethametsulfuron, ethaprochlor, ethephon, ethidimuron, ethiofencarb, ethiolate, ethion, ethiozin, ethiprole, ethirimol, ethoate-methyl, ethobenzanid, ethofumesate,ethohexadiol, ethoprop, ethoprophos, ethoxyfen, ethoxyquin, ethoxysulfuron, ethychlozate, ethyl formate, ethyl pyrophosphate, ethylan, ethyl-DDD, ethylene, ethylene dibromide, ethylene dichloride, ethylene oxide, ethylicin, ethylmercury 2,3- dihydroxypropyl mercaptide, ethylmercury acetate, ethylmercury bromide, ethylmercury chloride, ethylmercury phosphate, etinofen, ETM, etnipromid, etobenzanid, etofenprox, etoxazole, etridiazole, etrimfos, etrimphos, eugenol, EXD, famoxadone, famphur, fenac, fenamidone, fenaminosulf, fenaminstrobin, fenamiphos, fenapanil, fenarimol, fenasulam, fenazaflor, fenazaquin, fenbuconazole, fenbutatin oxide, fenchlorazole, fenchlorphos, fenclofos, fenclorim, fenethacarb, fenfluthrin, fenfuram, fenhexamid, fenidin, fenitropan, fenitrothion, fenizon, fenjuntong, fenobucarb, fenolovo, fenoprop, fenothiocarb, fenoxacrim, fenoxanil, fenoxaprop, fenoxaprop-P, fenoxasulfone, fenoxycarb, fenpiclonil, fenpirithrin, fenpropathrin, fenpropidin, fenpropimorph, fenpyrazamine, fenpyroximate, fenquinotrione, fenridazon, fenson, fensulfothion, fenteracol, fenthiaprop, fenthion, fenthion-ethyl, fentiaprop, fentin, fentrazamide, fentrifanil, fenuron, fenuron-TCA, fenvalerate, ferbam, ferimzone, ferric phosphate, ferrous sulfate, fipronil, flamprop, flamprop-M, flazasulfuron, flocoumafen, flometoquin, flonicamid, florasulam,fluacrypyrim, fluazifop, fluazifop- P, fluazinam, fluazolate, fluazuron, flubendiamide, flubenzimine, flubrocythrinate, flucarbazone, flucetosulfuron, fluchloralin, flucofuron, flucycloxuron, flucythrinate, fludioxonil, fluenethyl, fluenetil, fluensulfone, flufenacet, flufenerim, flufenican, flufenoxuron, flufenoxystrobin, flufenprox, flufenpyr, flufenzine, flufiprole, fluhexafon, flumethrin, flumetover, flumetralin, flumetsulam, flumezin, flumiclorac, flumioxazin, flumipropyn, flumorph, fluometuron, fluopicolide, fluopyram, fluorbenside, fluoridamid, fluoroacetamide, fluoroacetic acid, fluorochloridone, fluorodifen, fluoroglycofen, fluoroimide, fluoromide, fluoromidine, fluoronitrofen, fluoroxypyr, fluothiuron, fluotrimazole, fluoxastrobin, flupoxam, flupropacil, flupropadine, flupropanate, flupyradifurone, flupyrsulfuron, fluquinconazole, fluralaner, flurazole, flurecol, flurenol, fluridone, flurochloridone, fluromidine, fluroxypyr, flurprimidol, flursulamid, flurtamone, flusilazole, flusulfamide, flutenzine, fluthiacet, fluthiamide, flutianil, flutolanil, flutriafol, fluvalinate, fluxapyroxad, fluxofenim, folpel, folpet, fomesafen, fonofos, foramsulfuron, forchlorfenuron, formaldehyde, formetanate,formothion, formparanate, fosamine, fosetyl, fosmethilan, fospirate, fosthiazate, fosthietan, frontalin, fthalide, fuberidazole, fucaoj ing, fucaomi, fuj unmanzhi, fulumi, fumarin, funaihecaoling, fuphenthiourea, furalane, furalaxyl, furamethrin, furametpyr, furan tebufenozide, furathiocarb, furcarbanil, furconazole, furconazole-cis, furethrin, furfural, furilazole, furmecyclox, furophanate, furyloxyfen, gamma-QHC, gamma- cyhalothrin, gamma-hCH, genit, gibberellic acid, gibberellin A3, gibberellins, gliftor, glitor, glucochloralose, glufosinate, glufosinate-P, glyodin, glyoxime, glyphosate, glyphosine, gossyplure, grandlure, griseofulvin, guanoctine, guazatine, halacrinate, halauxifen, halfenprox, halofenozide, halosafen, halosulfuron, haloxydine, haloxyfop, haloxyfop-P, haloxyfop-R, HCA, HCB, HCH, hemel, hempa, HEOD, heptachlor, heptafluthrin, heptenophos, heptopargil, herbimycin, herbimycin A, heterophos, hexachlor, hexachloran, hexachloroacetone, hexachlorobenzene, hexachlorobutadiene, hexachlorophene, hexaconazole, hexaflumuron, hexafluoramin, hexaflurate, hexalure, hexamide, hexazinone, hexylthiofos, hexythiazox, HHDN, holosulf, homobrassinolide, huancaiwo, huanchongj ing, huangcaoling, huanj unzuo, hydramethylnon, hydrargaphen, hydrated lime, hydrogen cyanamide, hydrogen cyanide, hydroprene, hydroxyisoxazole, hymexazol, hyquincarb, IAA, IBA, IBP, icaridin, imazalil, imazamethabenz, imazamox, imazapic, imazapyr, imazaquin, imazethapyr, imazosulfuron, imibenconazole, imicyafos, imidacloprid, imidaclothiz, iminoctadine, imiprothrin, inabenfide, indanofan, indaziflam, indoxacarb, inezin, infusorial earth, iodobonil, iodocarb, iodofenphos, iodomethane, iodosulfuron, iofensulfuron, ioxynil, ipazine, IPC, ipconazole, ipfencarbazone, iprobenfos, iprodione, iprovalicarb, iprymidam, ipsdienol, ipsenol, IPSP, IPX, isamidofos, isazofos, isobenzan, isocarbamid, isocarbamide, isocarbophos, isocil, isodrin, isofenphos, isofenphos-methyl, isofetamid, isolan, isomethiozin, isonoruron, isopamphos, isopolinate, isoprocarb, isoprocil, isopropa lin, isopropazol, isoprothiolane, isoproturon, isopyrazam, isopyrimol, isothioate, isotianil, isouron, isovaledione, isoxaben, isoxachlortole, isoxadifen, isoxaflutole, isoxapyrifop, isoxathion, isuron, ivermectin, ixoxaben, izopamfos, izopamphos, japonilure, japothrins, jasmolin I, jasmolin II, jasmonic acid, j iahuangchongzong, j iajizengxiaolin, j iaxiangj unzhi, j iecaowa n, j iecaoxi, jinganmycin A, jodfenphos, juvenile hormone I, j uvenile hormone II, juvenile hormone III, kadethrin, kappa-bifenthrin, kappa-tefluthrin, karbutilate, karetazan, kasugamycin, kej unlin, kelevan, ketospiradox, kieselguhr, kinetin, kinoprene, kiralaxyl, kresoxim- methyl, kuicaoxi, lactofen, / amdc / a-cyhalothrin, latilure, lead arsenate, lenacil, lepimectin, leptophos, lianbenj ingzhi, lime sulfur, lindane, lineatin, linuron, lirimfos, litlure, looplure, lufenuron, luxiancaolin, Ivdingj unzhi, Ivfumijvzhi, Ivxiancaolin, lythidathion, M-74, M-81, MAA, magnesium phosphide, malathion, maldison, maleic hydrazide, malonoben, maltodextrin, MAMA, mancopper, mancozeb, mandestrobin, mandipropamid, maneb, matrine, mazidox, MCC, MCP, MCPA, MCPA-thioethyl, MCPB,MCPP, mebenil, mecarbam, mecarbinzid, mecarphon, mecoprop, mecoprop-P, medimeform, medinoterb, medlure, mefenacet, mefenoxam, mefenpyr, mefluidide, megatomoic acid, melissyl alcohol, melitoxin, M EMC, menazon, M EP, mepanipyrim, meperfluthrin, mephenate, mephosfolan, mepiquat, mepronil, meptyldinocap, mercaptodimethur, mercaptophos, mercaptophos thiol, mercaptothion, mercuric chloride, mercuric oxide, mercurous chloride, merphos, merphos oxide, mesoprazine, mesosulfuron, mesotrione, mesulfen, mesulfenfos, mesulphen, metacresol,metaflumizone, metalaxyl, metalaxyl-M, metaldehyde, metam, metamifop, metamitron, metaphos, metaxon, metazachlor, metazosulfuron, metazoxolon, metconazole, metepa, metflurazon, methabenzthiazuron, methacrifos, methalpropalin, metham,methamidophos, methasulfocarb, methazole, methfuroxam, methibenzuron,methidathion, methiobencarb, methiocarb, methiopyrisulfuron, methiotepa, methiozolin, methiuron, methocrotophos, metholcarb, methometon, methomyl, methoprene, methoprotryn, methoprotryne, methoquin-butyl, methothrin, methoxychlor,methoxyfenozide, methoxyphenone, methyl apholate, methyl bromide, methyl eugenol, methyl iodide, methyl isothiocyanate, methyl parathion, methylacetophos,methylchloroform, methyldithiocarbamic acid, methyldymron, methylene chloride, methyl- isofenphos, methylmercaptophos, methylmercaptophos oxide,methylmercaptophos thiol, methylmercury benzoate, methylmercury dicyandiamide, methylmercury pentachlorophenoxide, methylneodecanamide, methylnitrophos, methyltriazothion, metiozolin, metiram, metiram-zinc, metobenzuron, metobromuron, metofluthrin, metolachlor, metolcarb, metometuron, metominostrobin, metosulam, metoxadiazone, metoxuron, metrafenone, metriam, metribuzin, metrifonate, metriphonate, metsulfovax, metsulfuron, mevinphos, mexacarbate, miechuwei, mieshuan, miewenjuzhi, milbemectin, milbemycin oxime, milneb, mima2nan, mipafox, MIPC, mirex, MNAF, moguchun, molinate, molosultap, momfluorothrin, monalide, monisuron, monoamitraz, monochloroacetic acid, monocrotophos, monolinuron, monomehypo, monosulfiram, monosulfuron, monosultap, monuron, monuron-TCA, morfamquat, moroxydine, morphothion, morzid, moxidectin, M PMC, MSMA, MTMC, muscalure, myclobutanil, myclozolin, myricyl alcohol, N- (ethylmercury)-p- toluenesulphonanilide, NAA, NAAm, nabam, naftalofos, naled, naphthalene,naphthaleneacetamide, naphthalic anhydride, naphthalophos, naphthoxyacetic acids, naphthylacetic acids, naphthylindane- l,3-diones, naphthyloxyacetic acids, naproanilide, napropamide, napropamide-M, naptalam, natamycin, N BPOS, neburea, neburon, nendrin, neonicotine, nichlorfos, niclofen, niclosamide, nicobifen, nicosulfuron, nicotine, nicotine sulfate, nifluridide, nikkomycins, NIP, nipyraclofen, nipyralofen, nitenpyram, nithiazine, nitralin, nitrapyrin, nitrilacarb, nitrofen, nitrofluorfen, nitrostyrene, nitrothal- isopropyl, nobormide, nonanol, norbormide, norea, norflurazon, nornicotine, noruron,novaluron, noviflumuron, NPA, nuarimol, nuranone, OCH, octachlorodipropyl ether, octhilinone, o-dichlorobenzene, ofurace, omethoate, o-phenylphenol, orbencarb, orfralure, orthobencarb, ortho-dichlorobenzene, orthosulfamuron, oryctalure, orysastrobin, oryzalin, osthol, osthole, ostramone, ovatron, ovex, oxabetrinil, oxadiargyl, oxadiazon, oxadixyl, oxamate, oxamyl, oxapyrazon, oxapyrazone, oxasulfuron, oxathiapiprolin, oxaziclomefone, oxine-copper, oxine-Cu, oxolinic acid, oxpoconazole, oxycarboxin, oxydemeton-methyl, oxydeprofos, oxydisulfoton, oxyenadenine, oxyfluorfen, oxymatrine, oxytetracycline, oxythioquinox, PAC, paclobutrazol,paichongding, pallethrine, PAP, para-dichlorobenzene, parafluron, paraquat, parathion, parathion-methyl, parinol, Paris green, PCN B, PCP, PCP-Na, p-dichlorobenzene, PDJ, pebulate, pedinex, pefurazoate, pelargonic acid, penconazole, pencycuron,pendimethalin, penfenate, penflufen, penfluron, penoxalin, penoxsulam,pentachlorophenol, pentachlorophenyl laurate, pentanochlor, penthiopyrad, pentmethrin, pentoxazone, perchlordecone, perfluidone, permethrin, pethoxamid, PHC, phenamacril, phenamacril-ethyl, phenaminosulf, phenazine oxide, phenetacarbe, phenisopham, phenkapton, phenmedipham, phenmedipham-ethyl, phenobenzuron, phenothiol, phenothrin, phenproxide, phenthoate, phenylmercuriurea, phenylmercury acetate, phenylmercury chloride, phenylmercury derivative of pyrocatechol, phenylmercury nitrate, phenylmercury salicylate, phorate, phosacetim, phosalone, phosametine, phosazetim, phosazetin, phoscyclotin, phosdiphen, phosethyl, phosfolan, phosfolan- methyl, phosglycin, phosmet, phosnichlor, phosphamide, phosphamidon, phosphine, phosphinothricin, phosphocarb, phosphorus, phostin, phoxim, phoxim-methyl, phthalide, phthalophos, phthalthrin, picarbutrazox, picaridin, picloram, picolinafen, picoxystrobin, pimaricin, pindone, pinoxaden, piperalin, piperazine, piperonyl butoxide, piperonyl cyclonene, piperophos, piproctanly, piproctanyl, piprotal, pirimetaphos, pirimicarb, piriminil, pirimioxyphos, pirimiphos-ethyl, pirimiphos-methyl, pival, pivaldione, plifenate, PMA, PMP, polybutenes, polycarbamate, polychlorcamphene,polyethoxyquinoline, polyoxin D, polyoxins, polyoxorim, polythialan, potassium arsenite, potassium azide, potassium cyanate, potassium ethylxanthate, potassium naphthenate, potassium polysulfide, potassium thiocyanate, pp'-DDT, prallethrin, precocene I, precocene II, precocene III, pretilachlor, primidophos, primisulfuron, probenazole, prochloraz, proclonol, procyazine, procymidone, prodiamine, profenofos, profluazol, profluralin, profluthrin, profoxydim, profurite-aminium, proglinazine, prohexadione, prohydrojasmon, promacyl, promecarb, prometon, prometryn, prometryne, promurit, pronamide, propachlor, propafos, propamidine, propamocarb, propanil, propaphos, propaquizafop, propargite, proparthrin, propazine, propetamphos, propham,propiconazole, propidine, propineb, propisochlor, propoxur, propoxycarbazone, propyl isome, propyrisulfuron, propyzamide, proquinazid, prosuler, prosulfalin, prosulfocarb,prosulfuron, prothidathion, prothiocarb, prothioconazole, prothiofos, prothoate, protrifenbute, proxan, prymidophos, prynachlor, psoralen, psoralene, pydanon, pyflubumide, pymetrozine, pyracarbolid, pyraclofos, pyraclonil, pyraclostrobin, pyraflufen, pyrafluprole, pyramat, pyrametostrobin, pyraoxystrobin, pyrasulfotole, pyraziflumid, pyrazolate, pyrazolynate, pyrazon, pyrazophos, pyrazosulfuron, pyrazothion, pyrazoxyfen, pyresmethrin, pyrethrin I, pyrethrin II, pyrethrins, pyribambenz-isopropyl, pyribambenz-propyl, pyribencarb, pyribenzoxim, pyributicarb, pyriclor, pyridaben, pyridafol, pyridalyl, pyridaphenthion, pyridaphenthione, pyridate, pyridinitril, pyrifenox, pyrifluquinazon, pyriftalid, pyrimetaphos, pyrimethanil, pyrimicarbe, pyrimidifen, pyriminobac, pyriminostrobin, pyrimiphos-ethyl, pyrimiphos- methyl, pyrimisulfan, pyrimitate, pyrinuron, pyriofenone, pyriprole, pyripropanol, pyriproxyfen, pyrisoxazole, pyrithiobac, pyrolan, pyroquilon, pyroxasulfone, pyroxsulam, pyroxychlor, pyroxyfur, qincaosuan, qingkuling, quassia, quinacetol, quinalphos, quinalphos-methyl, quinazamid, quinclorac, quinconazole, quinmerac, quinoclamine, quinomethionate, quinonamid, quinothion, quinoxyfen, quintiofos, quintozene, quizalofop, quizalofop-P, quwenzhi, quyingding, rabenzazole, rafoxanide, R- diniconazole, rebemide, reglone, renriduron, rescalure, resmethrin, rhodethanil, rhodojaponin-III, ribavirin, rimsulfuron, rizazole, R-metalaxyl, rodethanil, ronnel, rotenone, ryania, sabadilla, saflufenacil, saij unmao, saisentong, salicylanilide, salifluofen, sanguinarine, santonin, S-bioallethrin, schradan, scilliroside, sebuthylazine, secbumeton, sedaxane, selamectin, semiamitraz, sesamex, sesamolin, sesone, sethoxydim, sevin, shuangjiaancaolin, shuangj ianancaolin, S-hydroprene, siduron, sifumijvzhi, siglure, silafluofen, silatrane, silica aerogel, silica gel, silthiofam, silthiopham, silthiophan, silvex, simazine, simeconazole, simeton, simetryn, simetryne, sintofen, S-kinoprene, slaked lime, SMA, S-methoprene, S-metolachlor, sodium arsenite, sodium azide, sodium chlorate, sodium cyanide, sodium fluoride, sodium fluoroacetate, sodiumhexafluorosilicate, sodium naphthenate, sodium o-phenylphenoxide, sodiumorthophenylphenoxide, sodium pentachlorophenate, sodium pentachlorophenoxide, sodium polysulfide, sodium silicofluoride, sodium tetrathiocarbonate, sodiumthiocyanate, solan, sophamide, spinetoram, spinosad, spirodiclofen, spiromesifen, spirotetramat, spiroxamine, stirofos, streptomycin, strychnine, sulcatol, sulcofuron, sulcotrione, sulfallate, sulfentrazone, sulfiram, sulfluramid, sulfodiazole, sulfometuron, sulfosate, sulfosulfuron, sulfotep, sulfotepp, sulfoxaflor, sulfoxide, sulfoxime, sulfur, sulfuric acid, sulfuryl fluoride, sulglycapin, sulphosate, sulprofos, sultropen, swep, tau- fluvalinate, tavron, tazimcarb, TBTO, TBZ, TCA, TCBA, TCMTB, TCNB, TDE,tebuconazole, tebufenozide, tebufenpyrad, tebufloquin, tebupirimfos, tebutam, tebuthiuron, tecloftalam, tecnazene, tecoram, tedion, teflubenzuron, tefluthrin, tefuryltrione, tembotrione, temefos, temephos, tepa, TEPP, tepraloxydim, teproloxydim,terallethrin, terbacil, terbucarb, terbuchlor, terbufos, terbumeton, terbuthylazine, terbutol, terbutryn, terbutr / ne, terraclor, terramicin, terramycin, tetcyclacis, tetrachloroethane, tetrachlorvinphos, tetraconazole, tetradifon, tetradisul, tetrafluron, tetramethrin, tetramethylfluthrin, tetramine, tetranectin, tetraniliprole, tetrapion, tetrasul, thallium sulfate, thallous sulfate, thenylchlor, tfteta-cypermethrin,thiabendazole, thiacloprid, thiadiazine, thiadifluor, thiamethoxam, thiameturon, thiapronil, thiazafluron, thiazfluron, thiazone, thiazopyr, thicrofos, thicyofen, thidiazimin, thidiazuron, thiencarbazone, thifensulfuron, thifluzamide, thimerosal, thimet, thiobencarb, thiocarboxime, thiochlorfenphim, thiochlorphenphime,thiocyanatodinitrobenzenes, thiocyclam, thiodan, thiodiazole-copper, thiodicarb, thiofanocarb, thiofanox, thiofluoximate, thiohempa, thiomersal, thiometon, thionazin, thiophanate, thiophanate-ethyl, thiophanate-methyl, thiophos, thioquinox,thiosemicarbazide, thiosultap, thiotepa, thioxamyl, thiram, thiuram, thuringiensin, tiabendazole, tiadinil, tiafenacil, tiaoj iean, TIBA, tifatol, tiocarbazil, tioclorim, tioxazafen, tioxymid, tirpate, TMTD, tolclofos-methyl, tolfenpyrad, tolprocarb, tolpyralate, tolyfluanid, tolylfluanid, tolylmercury acetate, tomarin, topramezone, toxaphene, TPN, tralkoxydim, tralocythrin, tralomethrin, tralopyril, transfluthrin, transpermethrin, tretamine, triacontanol, triadimefon, triadimenol, triafamone, triallate, tri-allate, triamiphos, triapenthenol, triarathene, triarimol, triasulfuron, triazamate, triazbutil, triaziflam, triazophos, triazothion, triazoxide, tribasic copper chloride, tribasic copper sulfate, tribenuron, tribufos, tributy Itin oxide, tricamba, trichlamide, trichlopyr, trichlorfon, trichlormetaphos-3, trichloronat, trichloronate, trichlorotrinitrobenzenes, trichlorphon, triclopyr, triclopyricarb, tricresol, tricyclazole, tricyclohexyltin hydroxide, tridemorph, tridiphane, trietazine, trifenmorph, trifenofos, trifloxystrobin,trifloxysulfuron, trifludimoxazin, triflumezopyrim, triflumizole, triflumuron, trifluralin, triflusulfuron, trifop, trifopsime, triforine, trihydroxytriazine, trimedlure, trimethacarb, trimeturon, trinexapac, triphenyltin, triprene, tripropindan, triptolide, tritac, trithialan, triticonazole, tritosulfuron, trunc-call, tuoyelin, uniconazole, uniconazole-P, urbacide, uredepa, valerate, validamycin, validamycin A, valifenalate, valone, vamidothion, vangard, vaniliprole, vernolate, vinclozolin, vitamin D3, warfarin, xiaochongliulin, xinj unan, xiwoj unan, xiwojunzhi, XMC, xylachlor, xylenols, xylylcarb, xymiazole, yishij ing, zarilamid, zeatin, zengxiaoan, zengxiaolin, zeta-cypermethrin, zincnaphthenate, zinc phosphide, zinc thiazole, zinc thiozole, zinc trichlorophenate, zinc trichlorophenoxide, zineb, ziram, zolaprofos, zoocoumarin, zoxamide, zuoanj unzhi, zuocaoan, zuoj unzhi, zuomihuanglong, a-chlorohydrin, a-ecdysone, a-multistriatin, a- naphthaleneacetic acids, and β-ecdysone;(2) the following molecules(a) A / -(3-chloro- l-(pyridin-3-yl)- l H-pyrazol-4-yl)-N-ethyl-3- ((3,3,3-trifluoropropyl)thio)propanamide (hereafter "AI- 1")F(b) (3S,6S,7R,8R)-8-benzyl-3-(3-((isobutyryloxy)methoxy)-4- methoxypicolinamido)-6-methyl-4,9-dioxo-l, 5-dioxonan-7-yl isobutyrate (hereafter "AI-2")(4) the following molecules in Table ATable A - Structure of M# - active ingredientsAs used in this disclosure, each of the above is an active ingredient. For more information consult the "Compendium of Pesticide Common Names" located at Alanwood.net and various editions, including the on-line edition, of "The Pesticide Manual " located at bcpcdata.com .A particularly preferred selection of active ingredients are 1 ,3 dichloropropene, chlorpyrifos, hexaflumuron, methoxyfenozide, noviflumuron, spinetoram, spinosad, and sulfoxaflor (hereafter "AIGA-2").Additionally, another particularly preferred selection of active ingredients are acequinocyl, acetamiprid, acetoprole, avermectin, azinphos-methyl, bifenazate, bifenthrin, carbaryl, carbofuran, chlorfenapyr, chlorfluazuron, chromafenozide, clothianidin, cyfluthrin, cypermethrin, deltamethrin, diafenthiuron, emamectin benzoate, endosulfan, esfenvalerate, ethiprole, etoxazole, fipronil, flonicamid, fluacrypyrim, gamma-cyhalothrin, halofenozide, indoxacarb, / amdda-cyhalothrin, lufenuron, malathion, methomyl, novaluron, permethrin, pyridalyl, pyrimidifen, spirodiclofen, tebufenozide, thiacloprid, thiamethoxam, thiodicarb, tolfenpyrad, and zeta-cypermethrin (hereafter "AIGA-3").The term "alkenyl " means an acyclic, unsaturated (at least one carbon-carbon double bond), branched or unbranched, substituent consisting of carbon and hydrogen, for example, vinyl, allyl, butenyl, pentenyl, and hexenyl .The term "alkenyloxy" means an alkenyl further consisting of a carbon-oxygen single bond, for example, allyloxy, butenyloxy, pentenyloxy, hexenyloxy.The term "alkoxy" means an alkyl further consisting of a carbon-oxygen single bond, for example, methoxy, ethoxy, propoxy, isopropoxy, butoxy, isobutoxy, and 25 tertbutoxy.The term "alkyl " means an acyclic, saturated, branched or unbranched, substituent consisting of carbon and hydrogen, for example, methyl, ethyl, propyl, isopropyl, butyl, and tertbutyl .The term "alkynyl " means an acyclic, unsaturated (at least one carbon-carbon triple bond), branched or unbranched, substituent consisting of carbon and hydrogen, for example, ethynyl, propargyl, butynyl, and pentynyl .The term "alkynyloxy" means an alkynyl further consisting of a carbon-oxygen single bond, for example, pentynyloxy, hexynyloxy, heptynyloxy, and octynyloxy.The term "aryl " means a cyclic, aromatic substituent consisting of hydrogen and carbon, for example, phenyl, naphthyl, and biphenyl.The term "biopesticide" means a microbial biological pest control agent that, in general, is applied in a similar manner to chemical pesticides. Commonly they are bacterial, but there are also examples of fungal control agents, including Trichoderma spp. and Ampeiomyces quisqualis. One well-known biopesticide example is Bacillus species, a bacterial disease of Lepidoptera, Coleoptera, and Diptera . Biopesticides include products based on entomopathogenic fungi (e.g. Metarhizium anisopliae), entomopathogenic nematodes (e.g. Steinernema feltiae), and entomopathogenic viruses (e.g. Cydia pomonella granulovirus) . Other examples of entomopathogenic organisms include, but are not limited to, baculoviruses, protozoa, and M icrosporidia . For the avoidance of doubt, biopesticides are active ingredients.The term "cycloalkenyl " means a monocyclic or polycyclic, unsaturated (at least one carbon-carbon double bond ) substituent consisting of carbon and hydrogen, for example, cyclobutenyl, cyclopentenyl, cyclohexenyl, norbornenyl, bicyclo[2.2.2]octenyl, tetrahydronaphthyl, hexahydronaphthyl, and octahydronaphthyl .The term "cycloalkenyloxy" means a cycloalkenyl further consisting of a carbon-oxygen single bond, for example, cyclobutenyloxy, cyclopentenyloxy, norbornenyloxy, and bicyclo[2.2.2 ]octenyloxy.The term "cycloalkyl" means a monocyclic or polycyclic, saturated substituent consisting of carbon and hydrogen, for example, cyclopropyl, cyclobutyl, cyclopentyl, norbornyl, bicyclo[2.2.2 ]octyl, and decahydronaphthyl .The term "cycloalkoxy" means a cycloalkyl further consisting of a carbon- oxygen single bond, for example, cyclopropyloxy, cyclobutyloxy, cyclopentyloxy, norbornyloxy, and bicyclo[2.2.2]octyloxy.The term "halo" means fluoro, chloro, bromo, and iodo.The term "haloalkoxy" means an alkoxy further consisting of, from one to the maximum possible number of identical or different, halos, for example, fluoromethoxy, trifluoromethoxy, 2,2-difluoropropoxy, chloromethoxy, trichloromethoxy, 1 , 1,2,2- tetrafluoroethoxy, and pentafluoroethoxy.The term "haloalkyl " means an alkyl further consisting of, from one to the maximum possible number of, identical or different, halos, for example, fluoromethyl, trifluoromethyl, 2,2-difluoropropyl, chloromethyl, trichloromethyl, and 1, 1,2,2- tetrafluoroethyl.The term "heterocyclyl " means a cyclic substituent that may be aromatic, fully saturated, or partially or fully unsaturated, where the cyclic structure contains at least one carbon and at least one heteroatom, where said heteroatom is nitrogen, sulfur, or oxygen . Examples are :( 1 ) aromatic heterocyclyl substituents aromatic heterocyclyl substituents include, but are not limited to, benzofuranyl, benzoimidazolyl, benzoisothiazolyl, benzoisoxazolyl, benzothienyl, benzothiazolyl, benzothiophenyl, benzoxazolyl, cinnolinyl, furanyl, imidazolyl, imidazolylpyridinyl, indazolyl, indolyl, isoindolyl, isoquinolinyl, isothiazolyl, isoxazolyl, oxadiazolyl, oxazolinyl, oxazolyl, phthalazinyl, pyrazinyl, pyrazolinyl, pyrazolyl, pyrazolopyridinyl, pyridazinyl, pyridyl, pyrimidinyl, pyrrolyl, pyrrolopyridinyl, quinazolinyl, quinolinyl, quinoxalinyl, tetrazolyl, thiadiazolyl, thiazolinyl, thiazolyl, thienyl, triazinyl, [ l,2,4]triazolo[ l ,5-c]pyrimidinyl, and triazolyl ;(2) fully saturated heterocyclyl substituents include, but are not limited to, piperazinyl, piperidinyl, morpholinyl, pyrrolidinyl, tetrahydrofuranyl,tetrahydropyranyl, tetrahydrothiophenyl, tetrahydrothiophenyl-oxide, andtetrahydrothiophenyl-dioxide;(3) partially or fully unsaturated heterocyclyl substituents include, but are not limited to, 2,3-dihydro-1H-imidazolonyl, 4,5-dihydro-isoxazolyl, 4,5-dihydro- oxazolyl, 2,3-dihydrophthalazinyl, 2,3-dihydrophthalazine-l,4-dionyl, 4, 5-dihydro-1H- pyrazolyl, 2,3-dihydro-[ l,3,4]-oxadiazolyl, 2,5-dioxoimidazolidinyl, 2,4-dioxo-l,3- diazaspiro[4.4]nonanylisoxazolidinonyl, indolinyl, imidazolidinonyl, isoxazolidinonyl, oxazolidinonyl, pyrimidine-2,4( 1H,3H)-dionyl, pyrrolidinonyl, 1,2,3,4-tetrahydro- pyrimidinyl, 1,2,3,4-tetrahydro-quinolinyl, and thioxothiazolidinonyl ; and(4) Additional examples of heterocyclyls include the following :thieta nyl thietanyl-oxide and thietanyl-dioxide.The term "locus" means a habitat, breeding ground, plant, seed, soil, material, or environment, in which a pest is growing, may grow, or may traverse. For example, a locus may be: where crops, trees, fruits, cerea ls, fodder species, vines, turf, and / orornamental plants, are growing ; where domesticated animals are residing ; the interior or exterior surfaces of buildings (such as places where grains are stored) ; the materials of construction used in buildings (such as impregnated wood); and the soil around buildings.The phrase "MoA Material" means an active ingredient having a mode of action(" MoA") as indicated in IRAC MoA Classification v. 7.3, located at irac-online.org . , which describes the following groups.( 1 ) Acetylcholinesterase (AChE) inhibitors, includes the following active ingredients alanycarb, aldicarb, bendiocarb, benfuracarb, butocarboxim,butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, triazamate, trimethacarb, XMC, xylylcarb, acephate, azamethiphos, azinphos-ethyl, azinphos-methyl, cadusafos,chlorethoxyfos, chlorfenvinphos, chlormephos, chlorpyrifos, chlorpyrifos-methyl, coumaphos, cyanophos, demeton-S-methyl, diazinon, dichlorvos / DDVP, dicrotophos, dimethoate, dimethylvinphos, disulfoton, EPN, ethion, ethoprophos, famphur, fenamiphos, fenitrothion, fenthion, fosthiazate, heptenophos, imicyafos, isofenphos, isopropyl O-(methoxyaminothio-phosphoryl) salicylate, isoxathion, malathion, mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion, parathion-methyl, phenthoate, phorate, phosalone, phosmet, phosphamidon, phoxim, pirimiphos- methyl, profenofos, propetamphos, prothiofos, pyraclofos, pyridaphenthion, quinalphos, sulfotep,tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon, vamidothion.(2) GABA-gated chloride channel antagonists, includes the following active ingredients chlordane, endosulfan, ethiprole, and fipronil .(3) Sodium channel modulators, includes the following active ingredients acrinathrin, allethrin, d-cis-trans allethrin, d-trans allethrin, bifenthrin, bioallethrin, bioallethrin S-cyclopentenyl, bioresmethrin, cycloprothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha- cypermethrin, toeia-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin [( 1R)-frans-isomers], deltamethrin, empenthrin [(EZ)- ( 1R)- isomers], esfenvalerate, etofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, tau-fluvalinate, halfenprox, imiprothrin, kadethrin, permethrin, phenothrin [( 1R)-trans-isomer], prallethrin, pyrethrins ( pyrethrum), resmethrin, silafluofen, tefluthrin,tetramethrin, tetramethrin [( 1R)- isomers], tralomethrin, and transfluthrin, and methoxychlor.(4) Nicotinic acetylcholi ne receptor (nAChR) agonists, includes the following active ingredients(4A) acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam,(4B) nicotine,(4C) sulfoxaflor,(4D) flupyradifurone,(4E) triflumezopyrim and dicloromezotiaz.(5) Nicotinic acetylcholi ne receptor (nAChR) allosteric activators, includes the following active ingredients spinetoram and spinosad .(6) Chloride channel activators, includes the following active ingredients abamectin, emamectin benzoate, lepimectin, and milbemectin.(7) Juvenile hormone mimics, includes the following active ingredients hydroprene, kinoprene, methoprene, fenoxycarb, and pyriproxyfen.(8) Miscellaneous nonspecific (multi-site) inhibitors, includes the following active ingredients methyl bromide, chloropicrin, sulfur / 1 fluoride, borax, and tartar emetic.(9) Modulators of Chordotonal Organs, includes the following active ingredients pymetrozine and flonicamid.( 10) Mite growth inhibitors, includes the following active ingredients clofentezine, hexythiazox, diflovidazin, and etoxazole.( 11) Microbial disruptors of insect midgut membranes, includes the following active ingredients Bacillus thuringiensis subsp. Israelensis, Bacillusthuringiensis subsp. aizawai, Bacillus thuringiensis subsp. Kurstaki, Bacillus thuringiensis subsp. tenebrionenis, Bt crop proteins (CrylAb, CrylAc, CrylFa, CrylA. 105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb, Cry34Ab l / Cry35Ab l), and Bacillus sphaericus.( 12) Inhibitors of mitochondrial ATP synthase, includes the following active ingredients tetradifon, propargite, azocyclotin, cyhexatin, fenbutatin oxide, and diafenthiuron.( 13) Uncouplers of oxidative phosphorylation via disruption of the proton gradient, includes the following active ingredients chlorfenapyr, DNOC, and sulfluramid .( 14) Nicotinic acetylcholine receptor (nAChR) channel blockers, includes the following active ingredients bensultap, cartap hydrochloride, thiocyclam, and thiosultap-sodium.( 15) Inhibitors of chitin biosynthesis, type 0, includes the following active ingredients bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, and triflumuron.( 16) Inhibitors of chitln biosynthesis, type 1, includes the following active ingredient buprofezin.( 17) Moulting disruptor, Dipteran, includes the following active ingredient cyromazine.( 18) Ecdysone receptor agonists, includes the following active ingredients chromafenozide, halofenozide, methoxyfenozide, and tebufenozide.( 19) Octopamine receptor agonists, includes the following active ingredient amitraz.(20) Mitochondrial complex III electron transport inhibitors, includes the following active ingredients hydramethylnon, acequinocyl, and fluacrypyrim.(21) Mitochondrial complex I electron transport inhibitors, includes the following active ingredients fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad, tolfenpyrad, and rotenone.(22) Voltage-dependent sodium channel blockers, includes the following active ingredients indoxacarb and metaflumizone.( 23) Inhibitors of acetyl CoA carboxylase, includes the following active ingredients spirodiclofen, spiromesifen, and spirotetramat.(24) Mitochondrial complex IV electron transport inhibitors, includes the following active ingredients, aluminium phosphide, ca lcium phosphide, phosphine, zinc phosphide, and cyanide.(25) Mitochondrial complex II electron transport inhibitors, includes the following active ingredients cyenopyrafen and cyflumetofen. and(28) Ryanodine receptor modulators, includes the following active ingredients chlorantraniliprole, cyantraniliprole, and flubendiamide.Groups 26 and 27 are unassigned in this version of the classification scheme.Additionally, there is a Group UN that contains active ingredients of unknown or uncertain mode of action. This group includes the following active ingredients, azadirachtin, benzoximate, bifenazate, bromopropylate, chinomethionat, cryolite, dicofol, pyridalyl, and pyrifluquinazon.The term "pest" means an organism that is detrimental to huma ns, or human concerns (such as, crops, food, livestock, etc. ), where said organism is from Phyla Arthropoda, Mollusca, or Nematoda . Particular examples are ants, aphids, bed bugs, beetles, bristletails, caterpillars, cockroaches, crickets, earwigs, fleas, flies,grasshoppers, grubs, hornets, killer bees, leafhoppers, lice, locusts, maggots, mites, moths, nematodes, planthoppers, psyllids, sawflies, scales, silverfish, slugs, snails, spiders, springtails, stink bugs, symphylans, termites, thrips, ticks, wasps, whiteflies, and wireworms.Additional examples are pests in( 1 ) Subphyla Chelicerata, Myrlapoda, and Hexapoda.(2) Classes of Arachnida, Symphyla, and Insecta.(3) Order Anoplura . A non-exhaustive list of particular genera includes, but is not limited to, Haematopinus spp. , Hoplopleura spp. , Linognathus spp.(Pediculus spp. , Polyplax spp., Solenopotes spp. , and Neohaematopinis spp. A non-exhaustive list of particular species includes, but is not limited to, Haematopinus asini, Haematopinus suis, Linognathus setosus, Linognathus ovillus, Pediculus humanus capitis, Pediculus humanus humanus, and Pthirus pubis.(4) Order Coleoptera. A non-exhaustive list of particular genera includes, but is not limited to, Aca nth os eel ides spp. , Agriotes spp. , Anthonomus spp., Apion spp. ,Apogonia spp., Araecerus spp. , Aulacophora spp. , Bruchus spp. , Cerosterna spp. , Cerotoma spp. , Ceutorhynchus spp. , Chaetocnema spp. , Colaspis spp. , Ctenicera spp. , Curculio spp., Cyclocephala spp. , Diabrotica spp. , Dinoderus spp. , Gnathocerus spp. , Hemicoelus spp, , Heterobostruchus spp. , Hypera spp. , Ips spp., Lyctus spp. , Megasceiis spp. , Meiigethes spp. , Mezium spp. , Niptus spp. , Otiorhynchus spp., Pantomorus spp., Phyllophaga spp. , Phyllotreta spp. , Ptinus spp. , Rhizotrogus spp. , Rhynchites spp. , Rhynchophorus spp. , Scolytus spp. , Sphenophorus spp. , Sitophilus spp. , Tenebrio spp. , and Tribolium spp. A non-exhaustive list of particular species includes, but is not limited to, Acanthoscelides obtectus, Agrilus planipennis, Ahasverus advena, Alphitobius diaperinus, Anoplophora glabripennis, Anthonomus grandis, Anthrenus verbasci, Anthrenus falvipes, Ataenius spretulus, Atomaria linearis, Attagenus unicolor,Bothynoderes punctiventris, Bruchus pisorum, Callosobruchus macuiatus, Carpophilus hemipterus, Cassida vittata, Cathartus quadricoilis, Cerotoma trifurcata, Ceutorhynchus assimilis, Ceutorhynchus napi, Conoderus scalaris, Conoderus stigmosus, Conotracheius nenuphar, Cotinis nitida, Crioceris asparagi, Cryptolestes ferrugineus, Cryptoiestes pusiilus, Cryptolestes turcicus, Cylindrocopturus adspersus, Deporaus marginatus, Dermestes lardarius, Dermestes macuiatus, Epilachna varivestis, Euvrilletta peltata, Faustinus cubae, Hylobius pales, Hylotrupes bajulus, Hypera postica, Hypothenemus hampei, Lasioderma serricorne, Leptinotarsa decemlineata, Limonius canus, Liogenys fuscus, Liogenys suturalis, Lissorhoptrus oryzophilus, Lophocateres pusiilus, Lyctus planicollis, Maecolaspis joliveti, Melanotus communis, Meiigethes aeneus, Melolontha melolontha, Necrobia rufipes, Oberea brevis, Oberea linearis, Oryctes rhinoceros, Oryzaephilus mercator, Oryzaephilus surinamensis, Oulema melanopus, Ouiema oryzae, Phyllophaga cuyabana, Polycaon stoutti, Popillia japonica, Prostephanus truncatus, Rhyzopertha dominica, Sitona lineatus, Sitophilus granarius, Sitophilus oryzae, Sitophilus zeamais, Stegobium paniceum, Tenebroides mauritanicus, Tribolium castaneum, Tribolium confusum, Trogoderma granarium, Trogoderma variabile, Xestobium rufovillosum, and Zabrus tenebrioides.(5) Order Dermaptera . A non-exhaustive list of particular species includes, but is not limited to, Forficula auricularia .(6) Order Blattaria. A non-exhaustive list of particular species includes, but is not limited to, Blattella germanica, Blattella asahinai, Blatta orientalis, Blatta lateralis, Parcoblatta pennsylvanica, Periplaneta americana, Periplaneta australasiae, Periplaneta brunnea, Periplaneta fuliginosa, Pycnosceius surinamensis, and Supella longipaipa.(7) Order Diptera . A non-exhaustive list of particular genera includes, but is not limited to, Aedes spp. , Agromyza spp. , Anastrepha spp. , Anopheles spp. , Bactrocera spp. , Ceratitis spp. , Chrysops spp. , Cochliomyia spp. , Contarinia spp., Culex spp. , Culicoides spp., Dasineura spp. , Delia spp. , Drosophila spp., Fannia spp. , Hylemya spp. , Liriomyza spp., Musca spp., Phorbia spp. , Pollenia spp. , Psychoda spp. , Simulium spp. , Tabanus spp. , and Tipula spp. A non-exhaustive list of particular species includes, but is not limited to, Agromyza frontella, Anastrepha suspensa, Anastrepha ludens, Anastrepha obliqua, Bactrocera cucurbitae, Bactrocera dorsalis, Bactrocera invadens, Bactrocera zonata, Ceratitis capitata, Dasineura brassicae, Delia platura, Fannia canicularis, Fannia scalaris, Gasterophilus intestinalis, Gracillia perseae, Haematobia irritans, Hypoderma lineatum, Liriomyza brassicae, Melophagus ovinus, Musca autumnalis, Musca domestica, Oestrus ovis, Oscinella frit, Pegomya betae, Piophila casei, Psila rosae, Rhagoletis cerasi, Rhagoletis pomonella, Rhagoletis mendax, Sitodiplosis mosellana, and Stomoxys calcitrans.(8) Order Hemiptera. A non-exhaustive list of particular genera includes, but is not limited to, Adelges spp. , Aulacaspis spp., Aphrophora spp. , Aphis spp. , Bemisia spp. , Ceroplastes spp., Chionaspis spp., Chrysomphalus spp. , Coccus spp. , Empoasca spp. , Euschistus spp. , Lepidosaphes spp., Lagynotomus spp., Lygus spp., Macrosiphum spp. , Nephotettix spp. , Nezara spp. , Nilaparvata spp., Philaenus spp. , Phytocoris spp. , Piezodorus spp. , Planococcus spp. , Pseudococcus spp., Rhopalosiphum spp. , Saissetia spp. , Therioaphis spp., Toumeyella spp. , Toxoptera spp. , Trialeurodes spp. , Triatoma spp. , and Unaspis spp. A non-exhaustive list of particular species includes, but is not limited to, Acrosternum hilare, Acyrthosiphon pisum, Aleyrodes proletella, Aleurodicus dispersus, Aleurothrixus floccosus, Amrasca biguttula biguttula, Aonidiella aurantii, Aphis gossypii, Aphis glycines, Aphis pomi, Aulacorthum solani, Bactericera cockerelli, Bagrada hilaris, Bemisia argentifolii, Bemisia tabaci, Blissus leucopterus, Boisea trivittata, Brachycorynella asparagi, Brevennia rehi, Brevicoryne brassicae, Cacopsylla pyri, Cacopsylla pyricola, Calocoris norvegicus, Ceroplastes rubens, Cimex hemipterus, Cimex lectularius, Dagbertus fasciatus, Dichelops furcatus, Diuraphis noxia, Diaphorina citri, Dysaphis plantaginea , Dysdercus suturellus, Edessa meditabunda, Eriosoma lanigerum, Eurygaster maura, Euschistus conspersus, Euschistus heros, Euschistus servus,Halyomorpha halys, Helopeltis antonii, Helopeltis theivora, Icerya purchasi, Idioscopusnitidulus, Laodelphax striatellus, Leptocorisa oratorius, Leptocorisa vahcornis, Lygus hesperus, Maconellicoccus hirsutus, Macrosiphum euphorbiae, Macrosiphum granarium, Macrosiphum rosae, Macrosteles quadrilineatus, Mahanarva frimbiolata, Megacopta cribraria, Metopolophium dirhodum, Mictis longicornis, Myzus persicae, Nephotettix cincticeps, Neurocolpus longirostris, Nezara viridula, Nilaparvata lugens, Parlatoria pergandii, Parlatoria ziziphi, Peregrinus maidis, Phylloxera vitifoliae, Physokermes piceae, Phytocoris californicus, Phytocoris relativus, Piezodorus guildinii, Poecilocapsus lineatus, Psallus vaccinicola, Pseudacysta perseae, Pseudococcus brevipes,Quadraspidiotus pernlciosus, Rhopalosiphum maidis, Rhopalosiphum padi, Saissetia oleae, Scaptocoris castanea, Schizaphis graminum, Sitobion avenae, Sogatella furcifera, Trialeurodes vaporariorum, Trialeurodes abutiloneus, Unaspis yanonensis, and Zulia entrerriana.(9) Order Hymenoptera. A non-exhaustive list of particular genera includes, but is not limited to, Acromyrmex spp. , Atta spp ., Camponotus spp. , Diprion spp., Dolichovespula spp. , Formica spp ., Monomorium spp., Neodiprion spp ., Paratrechina spp. , Pheidole spp. , Pogonomyrmex spp. , Polistes spp., Solenopsis spp. , Technomyrmex, spp. , Tetramorium spp. , Vespula spp., Vespa spp. , a nd Xylocopa spp. A non-exhaustive list of particular species includes, but is not limited to, Athalla rosae, Atta texana, Caliroa cerasi, Cimbex americana, Iridomyrmex humilis, Linepithema humile, MelliferaScutellata, Monomorium minimum, Monomorium pharaonis, Neodiprion sertifer, Solenopsis invicta, Solenopsis geminata, Solenopsis molesta, Solenopsis richtery, Solenopsis xyloni, Tapinoma sessile, and Wasmannia auropunctata.( 10) Order Isoptera. A non-exhaustive list of particular genera includes, but is not limited to, Coptotermes spp., Cornitermes spp. , Cryptotermes spp. , Heterotermes spp., Kalotermes spp., Incisitermes spp. , Macrotermes spp., Marginitermes spp.,Microcerotermes spp., Procornitermes spp. , Reticulitermes spp. , Schedorhinotermes spp., and Zootermopsis spp. A non-exhaustive list of particular species includes, but is not limited to, Coptotermes acinaciformis, Coptotermes curvignathus, Coptotermes frenchi, Coptotermes formosanus, Coptotermes gestroi, Cryptotermes brevis,Heterotermes aureus, Heterotermes tenuis, Incisitermes minor, Incisitermes snyderi, Microtermes obesi, Nasutitermes corniger, Odontotermes formosanus, Odontotermes obesus, Reticulitermes banyulensis, Reticulitermes grassei, Reticulitermes flavipes, Reticulitermes hageni, Reticulitermes hesperus, Reticulitermes santonensis,Reticulitermes speratus, Reticulitermes tibialis, and Reticulitermes virginicus.( 11) Order Lepidoptera. A non-exhaustive list of particular genera includes, but is not limited to, Adoxophyes spp., Agrotis spp., Argyrotaenia spp., Cacoecia spp. , Caloptilia spp. , Chilo spp. , Chrysodeixis spp., Colias spp., Crambus spp. , Diaphania spp., Diatraea spp., Earias spp. , Ephestia spp. , Epimecis spp., Feltia spp., Gortyna spp.,Helicoverpa spp. , Heliothis spp. , Indarbela spp. , Lithocolletis spp., Loxagrotis spp. , Malacosoma spp., Nemapogon spp. , Peridroma spp ., Phyl!onorycter spp., Pseudaietia spp. , Plutella spp., Sesamia spp., Spodoptera spp., Synanthedon spp. , and Yponomeuta spp. A non-exhaustive list of particular species includes, but is not limited to, Achaea janata, Adoxophyes orana, Agrotis ipsilon, Alabama argiliacea, Amorbia cuneana, Amyelois transitella, Anacamptodes defectaria, Anarsia lineatella, Anomis sabulifera, Anticarsia gemmatalis, Archips argyrospila, Archips rosana, Argyrotaenia citrana, Autographa gamma, Bonagota cranaodes, Borbo cinnara, Bucculatrix thurberiella, Capua reticulana, Carposina niponensis, Chlumetia transversa, Choristoneura rosaceana, Cnaphalocrocis medinalis, Conopomorpha cramerella, Corey ra cephalonica, Cossus cossus, Cydia caryana, Cydia funebrana, Cydia molesta, Cydia nigricana, Cydia pomonella, Darna diducta, Diaphania nitidalis, Diatraea saccharalis, Diatraeagrandiosella, Earias insulana, Earias vittella, Ecdytolopha aurantianum, Elasmopalpus iignosellus, Ephestia cautella, Ephestia elutella, Ephestia kuehniella, Epinotia aporema, Epiphyas postvittana, Erionota thrax, Estigmene acrea, Eupoecilia ambiguella, Euxoa auxiliaris, Galleria mellonella, Grapholita molesta, Hedylepta indicata, Helicoverpa armigera, Helicoverpa zea, Heliothis virescens, Hellula undalis, Keiferia !ycopersicella, Leucinodes orbonalis, Leucoptera coffeella, Leucoptera malifoliella, Lobesia botrana, Loxagrotis albicosta, Lymantria dispar, Lyonetia clerkella, Mahasena corbetti, Mamestra brassicae, Manduca sexta, Maruca testulalis, Metisa plana, Mythimna unipuncta,Neoleucinodes elegantalis, Nymphuia depunctalis, Operophtera brumata, Ostrinia nubilalis, Oxydia vesulia, Pandemis cerasana, Pandemis heparana, Papilio demodocus, Pectinophora gossypiella, Peridroma saucia, Perileucoptera coffeella, Phthorimaea operculella, Phyllocnistis citrella, Phyllonorycter blancardella, Pieris rapae, Plathypena scabra, Platynota idaeusalis, Plodia interpunctella, Plutella xylostella, Polychrosis viteana, Prays endocarpa, Prays oleae, Pseudaietia unipuncta, Pseudoplusia includens,Rachiplusia nu, Scirpophaga incertulas, Sesamia inferens, Sesamia nonagrioides, Setora nitens, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera exigua, Spodoptera frugiperda, Spodoptera eridania, Thecla basilides, Tinea pellionella, Tineola bisselliella, Trichoplusia ni, Tuta absoluta, Zeuzera coffeae, and Zeuzea pyrina.( 12) Order Mallophaga. A non-exhaustive list of particular genera includes, but is not limited to, Anaticola spp., Bovicola spp ., Chelopistes spp., Goniodes spp., Menacanthus spp., and Trichodectes spp. A non-exhaustive list of particular species includes, but is not limited to, Bovicola bovis, Bovicola caprae, Bovicola ovis, Chelopistes meleagridis, Goniodes dissimilis, Goniodes gigas, Menacanthus stramineus, Menopon gallinae, and Trichodectes canis.( 13) Order Orthoptera. A non-exhaustive list of particular genera includes, but is not limited to, Melanoplus spp. and Pterophylla spp. A non-exhaustive list ofparticular species includes, but is not limited to, Acheta domesticus, Anabrus simplex, Gryllotalpa africana, Gryllotalpa australis, Gryilotalpa brachyptera, Gryllotalpahexadactyla, Locusta migratoria, Microcentrum retinerve, Schistocerca gregaria, and Scudderia furcata.( 14) Order Psocoptera . A non-exhaustive list of particular species includes, but is not limited to, Liposcelis decolor, Llposcelis entomophila, Lachesilla quercus, and Trogium pulsatorium.( 15) Order Siphonaptera . A non-exhaustive list of particular species includes, but is not limited to, Ceratophyllus gallinae, Ceratophyllus niger, Ctenocephalides canis, Ctenocephalides felis, and Pulex irritans.( 16) Order Thysanoptera. A non-exhaustive list of particular genera includes, but is not limited to, Caliothrips spp. , Frankliniella spp., Scirtothrips spp., and Thrips spp. A non-exhaustive list of particular species includes, but is not limited to, Frankliniella bispinosa, Frankliniella fusca, Frankliniella occidentalis, Frankliniella schultzei,Frankliniella tritici, Frankliniella williamsi, Heliothrips haemorrhoidalis, Rhipiphorothrips cruentatus, Scirtothrips citri, Scirtothrips dorsalis, Taeniothrips rhopalantennalis, Thrips hawaiiensis, Thrips nigropilosus, Thrips orientalis, Thrips palmi, and Thrips tabaci.( 17) Order Thysanura. A non-exhaustive list of particular genera includes, but is not limited to, Lepisma spp. and Thermobia spp.( 18) Order Acarina. A non-exhaustive list of particular genera includes, but is not limited to, Acarus spp. , Aculops spp. , Argus spp., Boophilus spp., Demodex spp., Dermacentor spp. , Epitrimerus spp. , Eriophyes spp. , Ixodes spp., Oligonychus spp. , Panonychus spp. , Rhizoglyphus spp. , and Tetranychus spp. A non-exhaustive list of particular species includes, but is not limited to, Acarapis woodi, Acarus siro, Aceria mangiferae, Aculops lycopersici, Aculus pelekassi, Aculus schlechtendali, Amblyomma americanum, Brevipalpus obovatus, Brevipalpus phoenicis, Dermacentor variabilis, Dermatophagoides pteronyssinus, Eotetranychus carpini, Liponyssoides sanguineus, Notoedres cati, Oligonychus coffeae, Oligonychus ilicis, Ornithonyssus bacoti,Panonychus citri, Panonychus ulmi, Phyllocoptruta oleivora, Polyphagotarsonemus latus, Rhipicephalus sanguineus, Sarcoptes scabiei, Tegolophus perseaflorae, Tetranychus urticae, Tyrophagus longior, and Varroa destructor.( 19) Order Araneae. A non-exhaustive list of particular genera includes, but is not limited to, Loxosceles spp. , Latrodectus spp., and Atrax spp. A non-exhaustive list of particular species includes, but is not limited to, Loxosceles reclusa, Latrodectus mactans, and Atrax robustus.(20) Class Symphyla. A non-exhaustive list of particular species includes, but is not limited to, Scutigerella immaculata,(21) Subclass Collembola . A non-exhaustive list of particular species includes, but is not limited to, Bourietiella hortensis, Onychiurus armatus, Onychiurus fimetarius, and Sminthurus viridis.( 22) Phylum Nematoda. A non-exhaustive list of particular genera includes, but is not limited to, Aphelenchoides spp. , Beionolaimus spp. , Criconemella spp. ,Ditylenchus spp. , Globodera spp. , Heterodera spp. , Hirschmanniella spp. , Hoplolaimus spp. , Meloidogyne spp., Pratylenchus spp., and Radopholus spp. A non-exhaustive list of particular species includes, but is not limited to, Dirofilaria immitis, Globodera pallida, Heterodera glycines, Heterodera zeae, Meloidogyne incognita, Meloidogyne javanica, Onchocerca volvulus, Pratylenchus penetrans, Radopholus similis, and Rotylenchulus reniformis.(23) Phylum Mollusca A non-exhaustive list of particular species includes, but is not limited to, Arion vulgaris, Cornu aspersum, Deroceras reticulatum, Limax flavus, Milax gagates, and Pomacea canaliculata.A particularly preferred pest group to control is sap-feeding pests. Sap-feeding pests, in general, have piercing and / or sucking mouthparts and feed on the sap and inner plant tissues of plants. Examples of sap-feeding pests of particular concern to agriculture include, but are not limited to, aphids, leafhoppers, moths, scales, thrips, psyll ids, mealybugs, stinkbugs, and whiteflies. Specific examples of Orders that have sap-feeding pests of concern in agriculture include but are not limited to, Anoplura and Hemiptera . Specific examples of Hemiptera that are of concern in agriculture include, but are not limited to, Aulacaspis spp. , Aphrophora spp. , Aphis spp. , Bemisia spp. , Coccus spp. , Euschistus spp. , Lygus spp., Macrosiphum spp. , Nezara spp., and Rhopalosiphum spp.Another particularly preferred pest group to control is chewing pests. Chewing pests, in general, have mouthparts that allow them to chew on the plant tissue including roots, stems, leaves, buds, and reproductive tissues (including, but not limited to flowers, fruit, and seeds). Examples of chewing pests of particular concern to agricultural include, but are not limited to, caterpillars, beetles, grasshoppers, and locusts. Specific examples of Orders that have chewing pests of concern in agriculture include but are not limited to, Coleoptera and Lepidoptera . Specific examples of Coleoptera that are of concern in agriculture include, but are not limited to, Anthonomus spp., Cerotoma spp. , Chaetocnema spp ., Colaspis spp. , Cyclocephala spp. , Diabrotica spp. , Hypera spp. , Phyllophaga spp., Phyllotreta spp. , Sphenophorus spp., Sitophilus spp .The phrase "pesticidally effective amount" means the amount of a pesticide needed to achieve an observable effect on a pest, for example, the effects of necrosis, death, retardation, prevention, removal, destruction, or otherwise diminishing the occurrence and / or activity of a pest in a locus. This effect may come about when pestpopulations are repulsed from a locus, pests are incapacitated in, or around, a locus, and / or pests are exterminated in, or around, a locus. Of course, a combination of these effects can occur. Generally, pest populations, activity, or both are desirably reduced more than fifty percent, preferably more than 90 percent, and most preferably more than 99 percent. In general, a pesticidally effective amount, for agricultural purposes, is from about 0.0001 grams per hectare to about 5000 grams per hectare, preferably from about 0.0001 grams per hectare to about 500 grams per hectare, and it is even more preferably from about 0.0001 grams per hectare to about 50 grams per hectare.Detailed description of this disclosureThis document discloses molecules of Formula OneR12Formula Onewherein :(A) R1is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, (C1-C6)alkyl, (C3-C6)cycloalkyl, (C2-C6)alkenyl, (C3-C6)cycloalkenyl, (C2-C6)alkynyl, (G- C6)alkoxy, (C1-C6)haloalkyl, (C1-C6)halocycloalkyl, (C2-C6)haloalkenyl, (G- C6)halocycloalkenyl, (C1-C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- C6)alkyl, S(C1-C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, (G-C6)alkyl- S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(B) R2is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, (C1-C6)alkyl, (C1-C6)cycloalkyl, (C2-C6)alkenyl, (G-G ycloalkenyl, (C2-C6)alkynyl, (G- C6)alkoxy, (C1-C6)haloalkyl, (C3-C6)halocycloalkyl, (C2-C6)haloalkenyl, (G- C6)halocycloalkenyl, (G-C6)haloalkoxy, S(G-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- C6)alkyl, S(G-C6)haloalkyl, S(0)(G-C6)haloalkyl, S(0)2(G -C6)haloalkyl, (G-G)alkyl- S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(C) R3is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, (C1-C6)alkyl, (C3-C6)cycloalkyl, (G-G)alkenyl, (C1-C6)cycloalkenyl, (C2-C6)alkynyl, (G- C6)alkoxy, (C1-C6)haloalkyl, (C1-C6)halocycloalkyl, (C2-C6)haloalkenyl, (G- G)halocycloalkenyl, (C1-C6)haloalkoxy, S(G-G)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- C6)alkyl, S(C1-C6)haloalkyl, S(0)(G -G)haloalkyl, S(0)2(C1-C6)haloalkyl, (C1-G)alkyl- S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(D) R4is selected from the group consisting of H, F, CI, Br, I, CN , NH2, NO2, (C1-C6)alkyl, (C3-C6)cycloalkyl, (C2-C6)alkenyl, (C3-C6)cycloalkenyl, (C2-C6)alkynyl, (G- C6)alkoxy, (C1-C6)haloalkyl, (G-Gihalocycloalkyl, ( C2-C6)haloalkenyl, ( Cs- C6)halocycloalkenyl, (C1-C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- C6)alkyl, S(C1-C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, (G-C6)alkyl- S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(E) R5is selected from the group consisting of H, F, CI, Br, I, CN , NH2, NO2, (C1-C6)alkyl, (Cs-C6)cycloalkyl, ( C2-C6)alkenyl, (C3-C6)cycloalkenyl, (C2-C6)alkynyl, (G- C6)alkoxy, (G-GJhaloalkyl, (C3-C6)halocycloalkyl, ( C2-C6) aloalkenyl, (G- C6)halocycloalkenyl, (C1-C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- C6)alkyl, S(C1-C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, (C1-C6)alkyl- S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(F) R6is selected from the group consisting of H and (G-C6)a lkyl ;(G) R7is selected from the group consisting of H, F, CI, Br, and I;( H) R8is selected from the group consisting of F, CI, Br, and I;(I) R9is selected from the group consisting of H and (C1-C6)alkyl ;(J) Q1is selected from the group consisting of 0 and S;(K) Q2is selected from the group consisting of 0 and S;(L) R10is selected from the group consisting of H , (C1-C6)alkyl, (C2-C&)a lkenyl, (C1-C6)haloalkyl, (C1-C6)a lkyl(G-G)a lkoxy, C( =0)(C1-C6)alkyl, and (G-Ce)alkoxyC( = 0)(C1-C6)alkyl ;(M) R11is selected from the group consisting of H, F, CI, Br, I, CN, NH2, N02, (C1-C6)alkyl, ( C3-C6)cycloa lkyl, (C2-C6)alkenyl, (C3-C6)cycloalkenyl, (C2-Ce)alkynyl, (C i - C6)alkoxy, (C1-C6)haloalkyl, (C3-C6)halocycloalkyl, (C2-C6)haloalkenyl, (C3- C6)halocycloalkenyl, (C1-C6)haloalkoxy, S(G-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- C6)alkyl, S(G-C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(G -C6)haloalkyl, (G-C6)alkyl-S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(N) R12is selected from the group consisting of H, F, CI, Br, I, CN, NH2, N02, (C1-C6)alkyl, (C3-C6)cycloalkyl, (C2-C6)alkenyl, (C3-C6)cycloalkenyl, (C?-C6)alkynyl, (G- Ce)alkoxy, (C1-C6)haloalkyl, ( C3-C6)halocycloalkyl, (C2-C6)haloalkenyl, ( C3- C6)halocycloalkenyl, (C1-C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- C6)alkyl, S(C1-C6)haloalkyl, S(0)(C1-C6)haloalkyl#S(0)2(C1-C6)haloalkyl, (G-C6)alkyl-S(0)2NH2, and (G-C6)haloalkyl-S(0)2NH2;X1is selected from the group consisting of( 1 ) N,( 2) NO, and(3) CR13,wherein R13is selected from the group consisting of H, F, CI, Br, I, CN,NH2, N02, CHO, (C1-C6)alkyl, (C3-C6)cycloalkyl, (C2-C6)a lkenyl, (C3-C6)cycloalkenyl, (C2- C6)alkynyl, (C1-C6)a lkoxy, (C1-C6)haloalkyl, (C3-C6)halocycloa lkyl, (C2-C6) aloalkenyl, (C3-C6)halocycloa lkenyl, (C1-C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- C6)alkyl, S(C1-C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, (C1-C6)alkyl- S(0)2NH2, (C1-C6)haloalkyl-S(0)2NH2, and triazolyl ;(P) X2is selected from the group consisting of( 1 ) N,( 2) NO, and(3) CR14,wherein R14is selected from the group consisting of H, F, CI, Br, I, CN,NH2, NO2, (C1-C6)a lkyl, (C3-C6)cycloalkyl, (C2-C6)a lkenyl, (C3-C6)cycloalkenyl, (C2- C6)alkynyl, (C1-C6)a lkoxy, (C1-C6)haloalkyl, (C3-C6)halocycloa lkyl, (C2-C6)haloalkenyl, (C3-C6)halocycloa lkenyl, (C1-C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- C6)alkyl, S(G-C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, (G-C6)alkyl- S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(Q) X3is selected from the group consisting of N (R15)(substituted or unsubstituted phenyl), N (Rls)(substituted or unsubstituted heterocyclyl), and substituted or unsubstituted heterocyclyl,(a) wherein said R15is selected from the group consisting of H, (G- C6)alkyl, (C2-C6)alkenyl, (C2-C6)alkynyl, (C1-C6) haloalkyl, (C1-C6)alkyl(C1-C6)a lkoxy, C( = 0)(C1-C6)alkyl, and (C1-C6)alkoxyC( = 0)(C1-C6)alkyl,( b) wherein said substituted phenyl and substituted heterocyclyl has one or more substituents selected from the group consisting of F, CI, Br, I, H, CN, CHO, NHOH, NO, NO2, OH, (C1-C6)alkoxy, (C1-C6)alkyl, (G-C6)alkylphenyl, (G-C6)alkyl-S(0)2NH2, (G-C6)haloalkoxy, (C1-C6)haloalkyl, (G-C6)haloalkyl-S(0)2NH2, (C2-C6)a lkenyl, (C2-C6)alkynyl, (C1-C6)haloalkenyl, (C3-C6)cycloalkenyl, (C3-C6)cycloalkyl, (G- C6)halocycloalkenyl, (C3-G)halocycloa lkyl, (C1-C6)alkyl((C1-C6)alkyl)( = NO(C1-C6)alkyl), C( = NO(C1-C6)alkyl)(C1-C6)alkyl, C(0)(C1-C6)alkyl, C(0)NH(G-C6)a lkyl, C(0)NHphenyl, C(0)0(C1-C6)a lkyl, CH( = NO(C1-C6)alkyl ), imidazolyl, N ((C1-C6)alkyl)(C(0)(C1-C6)a lkyl), N((C1-C6)alkyl)(C(0)(C1-C6)alkyl-0(C1-C6)a lkyl), N ((C1-C6)alkyl)(C(0)(C1-C6)haloalkyl), N((C1-C6)alkyl)(C(0)0(C1-C6)alkyl), N((C,-C6)alkyl)2, N (C(0)0(C1-C6)alkyl)2, N = CH- phenyl, NH((C1-C6)alkylC(0)(C1-C6)a lkyl), NH(C(0)(G-C6)alkyl), NH(C(0)(C2-C6)alkenyl), NH(C(0)(C3-C6)cycloalkyl), NH(C1-C6)a lkyl, N H(C1-C6)alkenyl, NH(C1-C6)a lkynyl, NH(G- C6)alkylphenyl, NH(S(0)2(C1-C6)alkyl), NH2, NHC(0)(G-C6)a lkyl, NHC(0)(G- C6)alkylphenyl, NHC(0)(C1-C6)a lkylphenyl, NHC(0)(G-C6)haloalkyl, NHC(0)(C2- C6)alkenyl, N H-C(0)0(C1-C6)a lkyl, oxazolyl, phenyl, pyrazolyl, pyridinyl, S( = NCN)((G- C6)alkyl), S(C1-C6)a lkyl, S(C1-C6)haloalkyl, S(0)( = NCN )((C1-C6)alkyl), S(0)(C1-C6)a lkyl,S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)a lkyl, S(0)2(Ci-C6)haloa lkyl, SCN, thiazolyl, thienyl, and triazolyl,wherein each alkoxy, alkyl, haloalkoxy, haloalkyl, alkenyl, alkynyl, haloalkenyl, cycloalkenyl, cycloalkyl, halocycloalkenyl, halocycloalkyl, imidazolyl, phenyl, pyrazolyl, pyridinyl, thiazolyl, thienyl, and triazolyl, may be optionally substituted with one or more substituents selected from the group consisting of F, CI, Br, I, CN, OH, NH(C i-C6)alkyl, N H(C3-C6)cycloalkylCH20(Cl-C6)a lkyliNH(C3-C6)cycloalkylCH20(Ci- C6)haloalkyl, N HCH2(C3-C6)cycloalkyl, NH2;N02, oxo, (Cl-C6)a lkyl, (Ci-C6)a lkyl, (G- C6)alkoxy, and C(0)0-(C1-C6)a lkyl; andN-oxides, agriculturally acceptable acid addition salts, salt derivatives, solvates, ester derivatives, crystal polymorphs, isotopes, resolved stereoisomers, and tautomers, of the molecules of Formula One.The molecules of Formula One may exist in different geometric or optical isomeric or different tautomeric forms. One or more centers of chirality may be present in which case molecules of Formula One may be present as pure enantiomers, mixtures of enantiomers, pure diastereomers or mixtures of diastereomers. It will be appreciated by those skilled in the art that one stereoisomer may be more active than the other stereoisomers. Individual stereoisomers may be obtained by known selective synthetic procedures, by conventional synthetic procedures using resolved starting materials, or by conventional resolution procedures. There may be double bonds present in the molecule, in which case compounds of Formula One may exist as single geometric isomers (c / s or trans, E or Z) or mixtures of geometric isomers (c / s and trans, E and Z). Centers of tautomerisation may be present. This disclosure covers all such isomers, tautomers, and mixtures thereof, in all proportions.In another embodiment the molecules of Formula One, the carboxamido, and the phenyl, which are bonded to the cyclopropane, are in the R,R configuration. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R1is selected from the group consisting of H, F, or CI .. This embodiment may be used in combination with the other embodiments of R2, R3, R4, Rs, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R2is selected from the group consisting of H, F, CI, Br, CHs, and CF3. This embodiment may be used in combination with the other embodiments of R1, R3, R4, R5, R6, R7, R8, R9, R10, R", R12, Q1, Q2, X1, X2, and X3.In another embodiment R3is selected from the group consisting of H, F, CI, Br,CHs, CF3, and OCF3. This embodiment may be used in combination with the other embodiments of R1, R2, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R4is selected from the group consisting of H, F, CI, Br, CH3, and CFs. This embodiment may be used in combination with the other embodiments of R\ R2, R3, R5, R6, R7, R8, R9, R10, R11, R12, Ql, Q2, X1, X2, and X3.In another embodiment R5is selected from the group consisting of H and CI . This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R6is H . This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R7is selected from the group consisting of CI and Br. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, Rs, R6, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R8is selected from the group consisting of CI and Br. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R9, R10, R", R12, Q1, Q2, X1, X2, and X3.In another embodiment R9is H. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R10is H or CH3. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R11is selected from the group consisting of H, F, CI, and CH3. This embodiment may be used in combination with the other embodiments of R\ R2, R3, R4, R5, R6, R7, R8, R9, R10, R12, Q1, Q2, X1, X2, and X3.In another embodiment R12is selected from the group consisting of H and CI .This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, Q1, Q2, X1, X2, and X3.In another embodiment Qlis 0. This embodiment may be used in combination with the other embodiments of R\ R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q2, X1, X2, and X3.In another embodiment Q2is selected from the group consisting of 0 and S. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, X1, X2, and X3.In another embodiment X1is selected from the group consisting of N, NO, and CR13. This embodiment may be used in combination with the other embodiments of R\ R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X2, and X3In another embodiment R13is selected from the group consisting of H, F, CI, Br, I, CN, CH3, CF3, OCH3, OCF3, SCH3, S(0)CH3, S(0)2CH3, and triazolyl . This embodimentmay be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Ql, Q2, X2, and X3.In another embodiment X2is selected from the group consisting of N and CR14. This embodiment may be used in combination with the other embodiments of R\ R2, R3, R4, Rs, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, and X3.In another embodiment R14is selected from the group consisting of H, F, CI, and OCH3. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Ql, Q2, X1, and X3.In another embodiment X3is selected from the group consisting ofR15(5)R15IN1R24 ■L*(6)R15I1R 23 o(7) R 22>15 >21)22(8)>15 21I-N.NN-(9)"NVR 22N- / / (10)R15IR222(11) R'3>15N— R22R24(12) R23, andwherein :(a) R15is selected from the group consisting of H, (C1-C6)a lkyl, (C2-C6)alkenyl, (C2-C6)alkynyl, (C1-C6)haloalkyl, (C1-C6)alkyl(C1-C6)alkoxy, C( = 0)(C1-C6)alkyl, and (C1-C6)a lkoxyC(=0)(C1-C6)alkyl ;(b) X4is selected from the group consisting of(I ) N,(li ) NO, and(iii ) CR16,wherein R16is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, CHO, (C1-C6)alkyl, (G-G ycloalkyl, (C2-C6)a lkenyl, (C3-C6)cycloalkenyl, (C2-C6)alkynyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, (G- C6)halocycloalkyl, (C2-C6)haloalkenyl, (C3-C6)halocycloa lkenyl, (G- C6)haloalkoxy, S(G-C6)alkyl, S(0)(G-C6)a lkyl, S(0)2(C1-C6)alkyl, S(G- C6)haloalkyl, S(0)(G-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, CO(G-C6)alkyl, CH( = NO(C1-C6)alkyl), C( = NO(C1-C6)alkyl)(C1-C6)a lkyl, (G-C6)a lkyl- S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2,wherein each alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, alkoxy, haloalkyl, halocycloalkyl, haloalkenyl, halocycloalkenyl, and haloalkoxy, may be optionally substituted with one or more substituents selected from the group consisting of F, CI, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(0)0-(C1-C6)alkyl;(c) X5is selected from the group consisting of(i ) N,(ii ) NO, and(iii ) CR17,wherein R17is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, (G-C6)alkyl, (C3-C6)cycloalkyl, (C2-C6)a lkenyl, (C3-C6)cycloalkenyl, (C2-C6)alkynyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, (G- C6)halocycloalkyl, (C2-C6)haloalkenyl, (Cs-O halocycloalkenyl, (G- C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(C1-C6)alkyl, S(G- G)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, C(0)0(G- C6)alkyl, (C1-C6)alkyl-S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(d) X6is selected from the group consisting of(I) N,(li) NO, and(iii) and CR18,wherein R18is selected from the group consisting of H, F, CI, Br, I, CN, NO2, OH, NH2, SCN, CHO, (C1-C6)alkyl, (C2-G)alkenyl, (G- C6)alkynyl, (C1-C6)haloalkyl, (C1-C6)alkoxy, (C1-C6)haloalkoxy, NH(G- G)alkyl, N((C1-C6)alkyl)2, S(G-G)alkyl, S(0)(C1-C6)alkyl, S(0)2(G- G)alkyl, S(C1-C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, CO(C1-C6)alkyl, CONH(C1-C6)alkyl, NHCO(C1-C6)alkyl, N(G-G)alkyl- CO(C1-C6)alkyl, NHCO(G-C6)alkenyl, NHCO(C3-C6)cycloalkyl, NHCO(G- C6)haloalkyl, N(C1-C6)alkyl-CO(C1-C6)haloalkyl, NHCO(G-C6)alkylphenyl, NH-C(0)0(C1-C6)alkyl, N(C1-C6)alkyl-C(0)0(C1-C6)alkyl, CH( = NO(G- C6)alkyl), C( = NO(C1-C6)alkyl)(G-G)alkyl, phenyl, pyrazolyl, imidazolyl, and triazolyl,wherein each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, halocycloalkyl, cycloalkyl, phenyl, imidazolyl, and triazolyl, may be optionally substituted with one or more substituents selected from the group consisting of F, CI, Br, I, CN, OH, NH2, NO2, oxo, (G-G)alkyl, (G-G alkoxy, and C(0)0-(C1-C6)alkyl;(e) X7is selected from the group consisting of(i) N,(ii) NO, and(iii) CR19,wherein R19is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, (G-G)alkyl, (C3-C6)cycloalkyl, (C2-C6)alkenyl, (G- G)cycloalkenyl, (C2-C6)alkynyl, (G-Ce)alkoxy, (C1-C6)haloalkyl, (C3- Q halocycloalkyl, (C2-C6)haloalkenyl, (C3-C6)halocycloalkenyl, (G- Ce)haloalkoxy, S(G-C6)alkyl, S(0)(G-Ce)alkyl, S(0)2(G-Ce)alkyl, S(G- C6)haloalkyl, S(0)(G-C6)haloalkyl, S(0)2(G-C6)haloalkyl, C(0)0(G- Ce)alkyl, (C1-C6)alkyl-S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(f) X8is selected from the group consisting of(i) N,(ii ) NO, and(iii ) CR20,wherein R20is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, (G-Cejalkyl, (Cs-Cejcycloalkyl, (C2-C6)a lkenyl, (CB- C6)cycloalkenyl, (C2-C6)alkynyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, (C3- C6) alocycloalkyl, (C2-C6)haloalkenyl, (C3-C6) alocycloa lkenyl, (G- C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(C1-C6)alkyl, S(G- C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, C(0)0(G- G)alkyl, (G-C6)a lkyl-S(0)2NH2, and (C1-C6)haloalkyl-S(0)2NH2;(g ) R21is selected from the group consisting of H, F, CI, Br, I,CN, NH2, NO2, (C1-C6)alkyl, ( C3-C6)cycloalkyl, (C2-C6)alkenyl, (G- C6)cycloalkenyl, (C2-C6)alkynyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, (G- C6)ha locycloalkyl, (C2-C6)haloalkenyl, (C3-C6)halocycloalkenyl, (G- G)ha loalkoxy, S(G-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(G-G)alkyl, S(G- G)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(G-G)haloalkyl, (G-G)a lkyl-S(0)2NH2, (C1-C6)haloalkyl-S(0)2NH2, phenyl, pyridinyl, and thienyl,wherein each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl, and triazolyl, may be optionally substituted with one or more substituents selected from the group consisting of F, CI, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(0)0-(C1-C6)alkyl.(h) R22is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, (C1-C6)alkyl, (G-GJcycloalkyl, (C2-C6)alkenyl, (C3- C6)cycloalkenyl, (C2-C6)alkynyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, (C3- C6)ha locycloalkyl, (C2-C6)haloalkenyl, (C3-C6)halocycloalkenyl, (G- C6)ha loalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(C1-C6)alkyl#S(Ci- C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, (C1-C6)alkyl- S(0)2NH2, (C1-C6)haloalkyl-S(0)2NH2, phenyl, pyridinyl, and thienyl,wherein each alkyl, alkenyl, alkynyl, haloalkyl, a lkoxy, ha loalkoxy, phenyl, imidazolyl, and triazolyl, may be optiona lly substituted with one or more substituents selected from the group consisting of F, CI,Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(0)0-(Ci- C6)alkyl.(I ) R23is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, (C1-C6)alkyl, ( C3-C6)cycloalkyl, (C2-C6)alkenyl, (C3- C6)cycloalkenyl, (C2-C6)alkynyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, (C3- C6)ha locycloalkyl, (C2-C6)haloalkenyl, (C3-C6)halocycloalkenyl, (Ci- C6)ha loalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(C1-C6)alkyl, S(Ci-C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(C1-C6)haloalkyl, (C1-C6)alkyl- S(0)2NH2, (C1-C6)haloalkyl-S(0)2NH?, phenyl, pyridinyl, and thienyl,wherein each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl, and triazolyl, may be optionally substituted with one or more substituents selected from the group consisting of F, CI, Br, I, CN, OH, NH2, N02, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(0)0-(Ci- C6)alkyl.(j) R24is selected from the group consisting of H, F, CI, Br, I, CN, NH2, NO2, (C1-C6)alkyl, (Cs-Cejcycloalkyl, (C2-C6)alkenyl, (Cs- C6)cycloalkenyl, (C2-C6)alkynyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, (Cs- C6)halocycloalkyl, (C2-C6)haloalkenyl, (C3-C6)halocycloa lkenyl, (G- C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(C1-C6)alkyl, S(Ci- C6)haloalkyl, S(0)(C1-C6)haloalkyl, S(0)2(G-C6)haloalkyl, (C1-C6)alkyl- S(0)2NH2, (C1-C6)haloalkyl-S(0)2NH2, phenyl, pyridinyl, and thienyl,wherein each alkyl, alkenyl, alkynyl, haloalkyl, a lkoxy, haloalkoxy, phenyl, imidazolyl, and triazolyl, may be optionally substituted with one or more substituents selected from the group consisting of F, CI, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(0)0-(G- G)alkyl.This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Ql, Q2, X1, and X2.In another embodiment X3is selected from the group consisting ofR15(6) R , andR15(7) RThis embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Ql, Q2, X1, and X2.In another embodiment X3said substituted or unsubstituted heterocyclyl is selected from the group consisting of indolyl, oxazolyl, pyrazinyl, pyrazolyl, pyridazinyl, pyridyl, pyrimidinyl, tetrazolyl, thiadiazolyl, thiazolyl, thienyl, triazinyl,[l,2,4]triazolo[ l,5-c]pyrimidinyl, triazolyl, 2,3-dihydrophthalazine-l,4-dionyl, indolinyl, and pyrimidine-2,4( 1H,3H)-dionyl, wherein substituents are selected from the group consisting of F, CI, Br, I, H, CN, NH2, N02, (C1-C6)alkoxy, (G-C6)alkyl, (C1-C6)haloalkoxy, (C1-C6)haloalkyl, (C2-C6)haloa lkenyl, (C3-C6)halocycloa lkenyl, and (C3-C6)halocycloalkyl. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, Rs, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, and X2.In another embodiment X3said substituted or unsubstituted heterocyclyl is selected from the group consisting of indolinyl, oxazolyl, pyridyl, and thiadiazolyl, wherein substituents are selected from the group consisting of F, CI, Br, I, H, CN, NO2,NH2, (C1-C6)alkoxy, (G-C6)alkyl, (C1-C6)haloalkoxy, (C1-C6) haloalkyl, (C2-C6)ha loalkenyl, (C3-C6)halocycloa lkenyl, and (C3-C6)halocycloalkyl . This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, and X2.In another embodiment X3is N (Rls)(substituted or unsubstituted phenyl),(a) wherein said R15is selected from the group consisting of H, and (C1-C6)alkyl,(b) wherein said substituted phenyl has one or more substituents selected from the group consisting of F, CI, Br, I, CN , NO2, NH2, (G-C6)alkoxy, (G- C6)alkyl, (C1-C6)haloa lkoxy, (C1-C6)haloa lkyl, (C1-C6)ha loalkenyl, (C3-C6)cycloalkenyl, (G- C6)cycloalkyl, (C3-C6)halocycloalkenyl, and (C3-C6)halocycloalkyl. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, and X2.In another embodiment R15is selected from the group consisting of H, CH3, CH2CH3, CH2CH2CH3, CH2CH = CH2, CH2-C≡CH, and CH2CF3. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment X4is selected from the group consisting of N and CR16. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R", R12, Q1, Q2, X1, X2, and X3.In another embodiment R16is selected from the group consisting of H, F, CI, CN,NH2, CH3, CH2CH3, and CH2(CH3)2. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment X5is selected from the group consisting of N, NO, and CR17. This embodiment may be used in combination with the other embodiments of Rl, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R17is selected from the group consisting of H, F, CI, and CN, NH2. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment X6is selected from the group consisting of N, NO, and CR18. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q\ Q2, X1, X2, and X3In another embodiment R18is selected from the group consisting of H, F, CI, CN, NO2, NH2, CH3, CF3, OCH3, OCHCF2, OCF3, SCH3, S(0)CH3, S(0)2CH3, C(0)NHCH3, and NHC(0)CH3. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment X7is CR19. This embodiment may be used in combination with the other embodiments of R\ R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R19is selected from the group consisting of H, F, andNH2. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment X8is CR20. This embodiment may be used in combination with the other embodiments of R\ R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Ql, Q2, X1, X2, and X3.In another embodiment R20is selected from the group consisting of H, F, CI, andCH3. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R21is H. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R22is H. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q1, Q2, X1, X2, and X3.In another embodiment R23is H. This embodiment may be used in combination with the other embodiments of R\ R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Ql, Q2, X1, X2, and X3.In another embodiment R24is H. This embodiment may be used in combination with the other embodiments of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, Q\ Q2, X1, X2, and X3.In another embodiment:(A) R1, R2, R3, R4, R5, R11, and R12are each independently selected from the group consisting of H, F, CI, Br, (C1-C6)alkyl, (C1-C6)haloalkyl, and (C1-C6)haloalkoxy;(B) R6and R9are H ;(C) R7is selected from the group consisting of CI and Br;(D) R8is selected from the group consisting of CI and Br;(E) Q1and Q2are each independently selected from the group consisting of 0 and S;( F) R10is H ;(G) X1is selected from the group consisting of( 1 ) N,(2) NO, and(3) CR13,wherein R13is selected from the group consisting of H, F, CI, Br, I, CN(Ci -G alkyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, (C1-C6)ha loa lkoxy, S(C1-C6)alkyl, S(0)(G- C6)alkyl, S(0)2(C1-C6)alkyl, and triazolyl ;(H) X2is selected from the group consisting of( 1 ) N and(2) CR14,wherein R14is selected from the group consisting of H, F, CI, and (G- C6)alkoxy;(I) X3is selected from the group consisting ofR15( 1 )(2)(6)(7)wherein:(a) R15is selected from the group consisting of H, (C1-C6)alkyl, (C2-C6)alkenyl, and (C1-C6)haloalkyl;(b) X4is selected from the group consisting of(i) N, and(ii) CR16,wherein R16is selected from the group consisting of H, F, CI, CN, NH2, and (C1-C6)alkyl;(c) X5is selected from the group consisting of(I) N,(ii) NO, and(iii) CR17,wherein R17is selected from the group consisting of H, F, CI,NH2.and CN;(d) X6is selected from the group consisting of(i) N,(ii) NO, and(iii) and CR18,wherein R18is selected from the group consisting of H, F, CI, CN, N02(NH2, (C1-C6)alkyl, (G-G haloalkyl, (G-C6)alkoxy, (G- C6)haloalkoxy, S(C1-C6)alkyl, S(0)(G-C6)alkyl, S(0)2(G-C6)alkyl,25 CONH(G-C6)alkyl, and NHCO(G-C6)alkyl;(e) X7is CR19,wherein R19is selected from the group consisting of H, NH?, and F;(f) X8is CR20,wherein R20is selected from the group consisting of H, F, CI,NH2, and (C1-C6)alkyl; and(g) R21, R22, R23, and R24are H.In another embodiment:(A) R1is H;(B) R2is selected from the group consisting of H, CI, Br, (C1-C6)alkyl, and (G- C6)haloalkyl;(C) R3is selected from the group consisting of H, F, CI, Br, (C1-C6)alkyl, (G- C6)haloalkyl, and (G-Ce)haloalkoxy;(D) R4is selected from the group consisting of H, CI, Br, (G-G alkyl, and (G- C6)haloalkyl;(E) R5is selected from the group consisting of H and CI;(F) R6is H;(G) R7is selected from the group consisting of CI and Br;(H) R8is selected from the group consisting of CI and Br;(I) R9is H;(J) Q1is 0;(K) Q2is selected from the group consisting of 0 and S;(L) R10is H;(M) R11is selected from the group consisting of H, F, CI, and (C1-C6)alkyl; (N) R12is selected from the group consisting of H and CI;(O) X1is selected from the group consisting of(1) N,(2) NO, and(3) CR13,wherein R13is selected from the group consisting of H, F, CI, Br, I, CN, (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, (C1-C6)haloalkoxy, S(C1-C6)alkyl, S(0)(G- G)alkyl, S(0)2(C1-C6)alkyl, and triazolyl;(P) X2is selected from the group consisting of(1) N and(2) CR14,wherein R14is selected from the group consisting of H, F, CI, and (G- Ce)alkoxy; and(Q) X3is selected from the group consisting of) 15(7) R22wherein:(a) R15is selected from the group consisting of H, (C1- C6)alkyl, (C2-C6)alkenyl, and (C1-C6)haloalkyl;(b) X4is selected from the group consisting of(i) N, and(ii) CR16,wherein R16is selected from the group consisting of H, F, CI, CN, NH2, and (C1-C6)alkyl;(c) X5is selected from the group consisting of(I) N,(Ii) NO, and(iii) CR17,wherein R17is selected from the group consisting of H, F, CI,NH2. and CN;(d) X6is selected from the group consisting of(i) N,(II) NO, and(iii ) and CR18,wherein R18is selected from the group consisting of H, F, CI, CN, NO2, NH2, (C1-C6)alkyl, (C1-C6)haloalkyl, (G-C6)a lkoxy, (G- C6)haloalkoxy, S(C1-C6)alkyl, S(0)(C1-C6)alkyl, S(0)2(C1-C6)alkyl,CONH(C1-C6)alkyl, and NHCO(C1-C6)alkyl;(e) X7is CR19,wherein R19is selected from the group consisting of H, NH2, and F;(f) X8is CR20,wherein R20is selected from the group consisting of H, F, CI,NH2. and (C1-C6)alkyl ; and(g ) R21, R22, R23, and R24are H.In another embodiment:(A) R1is selected from the group consisting of H, F, or CI ;(B) R2is selected from the group consisting of H, F, CI, Br, (C1-C6)a lkyl, and (C1-C6)haloalkyl ;(C) R3is selected from the group consisting of H, F, CI, Br, (C1-C6)alkyl, (G- C6)haloalkyl, and (C1-C6)haloalkoxy;(D) R4is selected from the group consisting of H, F, CI, Br, (C1-C6)alkyl, and (C1-C6)haloalkyl;(E) R5is selected from the group consisting of H, F, and CI;(F) R6is H ;(G) R7is selected from the group consisting of CI and Br;(H) R8is selected from the group consisting of CI and Br;(I) R9is H ;(J) Q1is 0;(K) Q2is selected from the group consisting of 0 and S;(L) R10is H;( M) R11is selected from the group consisting of H, F, CI, and (C1-C6)alkyl ; ( N) R12is selected from the group consisting of H and CI ;(O) X1is CR13,wherein R13is selected from the group consisting of H, F, CI, Br, I, CN , (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)haloalkyl, and (C1-C6)haloalkoxy;(P) X2is CR14,wherein R14is selected from the group consisting of H, F, CI, and (G- G)alkyl, (C1-C6)a lkoxy, (C1-C6)haloalkyl, and (C1-C6)haloa lkoxy; and(Q) X3isR15wherein :R15is selected from the group consisting of H, (G-Cejalkyl, (C2-C6)alkenyl, and (C1-C6)haloalkyl;X4is CR16wherein R16is selected from the group consisting of H, F, CI,NH2. CN , NO2, (C1-C6)alkyl, (C1-C6)haloalkyl, (C1-C6)alkoxy, and (C1-C6)haloa lkoxy;X5is CR17wherein R17is selected from the group consisting of H, F, CI,NH2, CN , NO2, (C1-C6)alkyl, (C1-C6)haloalkyl, (C1-C6)a lkoxy, and (C1-C6)haloa lkoxy;X6is CR18wherein R18is selected from the group consisting of H, F, CI,NH2, CN, NO2, (C1-C6)alkyl, (C1-C6)haloalkyl, (G -Ce)a lkoxy, and (G -Ce)haloa lkoxy;X7is CR19wherein R19is selected from the group consisting of H, F, CI,NH2, CN, NO2, (C1-C6)alkyl, (C1-C6)haloalkyl, (C1-C6)a lkoxy, and (C1-C6)haloa lkoxy;X8is CR20wherein R20is selected from the group consisting of H, F, CI, CN, NH2, NO2, (G -G)alkyl, (C1-C6)haloalkyl, (G -Ce)a lkoxy, and (C1-C6)haloa lkoxy.Preparation of cyclopropyl carboxylic acidsStilbenes 1-1, wherein R1, R2, R3, R4, R5, R6, and R9are as previously disclosed, may be treated with a base such as sodium hydroxide in the presence of a carbene source such as chloroform or bromoform a nd a phase transfer catalyst such as / V-benzyl- / V,W-diethylethanaminium chloride in a polar protic solvent such as water attemperatures from about 0C'C to about 40 °C to provide diaryl cyclopropanes 1-2, wherein R1, R2, R3, R4, Rs, R6, R7, R8, and R9are as previously disclosed (Scheme 1, step a). Treatment of diaryl cyclopropanes 1-2 with a transition metal such as ruthenium(III) chloride in the presence of a stoichiometric oxidant such as sodium periodate in a solvent mixture preferably water, ethyl acetate, and acetonitrile at temperatures from about 0 °C to about 40C'C may provide cyclopropyl carboxylic acids 1-3, wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9are as previously disclosed (Scheme 1 , step b).Scheme 1Thiophene carbonyl 1.4-1 , wherein R9is as previously disclosed, may be treated with a lkoxy benzyl phosphonate 2-2, wherein R1, R2, R4, Rsare as previously disclosed, in the presence of a base such as sodium methoxide in a polar aprotic solvent such as Λ / , V-dimethylformamide at temperatures from about - 10 °C to about 80 °C to provide stilbene 1.4-2, wherein R1, R2, R4, R5, R6, and R9are as previously disclosed (Scheme 1.4, step a). Stilbene 1.4-2, wherein R1, R2, R4, R5, R6, and R9are as previously disclosed, may be treated with a base such as sodium hydroxide in the presence of a carbene source such as chloroform or bromoform and a phase transfer catalyst such asV-benzyl- V,W-diethylethanaminium chloride in a polar protic solvent such as water at temperatures from about 0 °C to about 40 °C to provide thiophene cyclopropane 1.4-3, wherein R1, R2, R4, Rs, R6, R7, R8, and R9are as previously disclosed (Scheme 1.4, step b). Treatment of thiophene cyclopropane 1.4-3 with a transition metal such as ruthenium(III) chloride in the presence of a stoichiometric oxidant such as sodium periodate in a solvent mixture preferably water, ethyl acetate, and acetonitrile at temperatures from about 0 °C to about 40 °C may provide cyclopropyl carboxylic acid 1- 3, wherein R3is a (G-C- alkoxy group and R1, R2, R4, R5, R6, R7, R8, and R9are as previously disclosed (Scheme 1.4, step c) .R7R8(Cx-C^alkyl (C C4)alkyl1.4-3Phenyl carbonyls 1.7-1, wherein R1, R2, R3, R4, R5, and R6are as previously disclosed, may be treated with alkoxy phosphonate 1.7-2 in the presence of a base such as sodium hydride in a polar aprotic solvent such as tetrahydrofuran at temperatures from about -10 °C to about 40 °C to provide stilbenes 1.7-3, wherein R1, R2, R3, R4, R5, R6, and R9are as previously disclosed (Scheme 1.7 , step a). Stilbenes 1.7-3, wherein R1, R2, R3, R4, R5, R6, and R9are as previously disclosed, may be treated with a reducing agent such as diisobutylaluminum hydride (DIBAL) in a polar aprotic solvent such as toluene at temperatures from about -80 °C to about 0 °C to provide alcohols1.7-4, wherein R1, R2, R3, R4, Rs, R6, and R9are as previously disclosed (Scheme 1.7, step b). Alcohols 1.7-4, wherein R1, R2, R3, R4, R5, R6, and R9are as previously disclosed, may be protected by treatment with 3,4-dihydro-2H-pyran in the presence of an acid catalyst such as p-toluenesulfonic acid in a polar aprotic solvent such as diethyl ether at temperatures from about 0 °C to about 40 °C to give protected stilbenes 1.7-5, wherein R1, R2, R3, R4, R5, R6, and R9are as previously disclosed (Scheme 1.7, step c). Protected stilbenes 1.7-5, wherein R1, R2, R3, R4, R5, R6, and R9are as previously disclosed, may be treated with a base such as sodium hydroxide in the presence of a carbene source such as chloroform or bromoform and a phase transfer catalyst such as / V-benzyl- / V, / V-diethylethanaminium chloride in a polar protic solvent such as water at temperatures from about 0 °C to about 40 °C to provide cyclopropanes 1.7-7, wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9are as previously disclosed (Scheme 1.7, step d). Cyclopropanes 1.7-6, wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9are as previously disclosed, may be treated with an acid such as p-toluenesulfonic acid in a polar protic25 solvent such as methanol at temperatures from about 0 °C to about 40 °C to providealcohols 1.7-7, wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9are as previously disclosed (Scheme 1.7, step e). Treatment of alcohols 1.7-7, wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9are as previously disclosed, with an oxidant such as Jones reagent in a polar aprotic solvent such as acetone at temperatures from about -10 °C to about 40 °C to provide cyclopropyl carboxylic acids 1-3, wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9are as previously disclosed (Scheme 1.7, step f).Scheme 1.7R6O O R5O1.7-6 1.7-7 1-3 Preparation of stilbenesStilbenes 1-1 may be prepared by several different methods as outlined in Scheme 2. Phenyl carbonyls 2-1, wherein R1, R2, R3, R4, Rs, and R6are as previously disclosed, may be treated with alkoxy benzyl phosphonates 2-2 in the presence of a base such as sodium methoxide in a polar aprotic solvent such as N,N- dimethylformamide at temperatures from about - 10 °C to about 30 °C and subsequently heated to 40 °C to about 80 °C to provide stilbenes 1-1 (Scheme 2, step a).Scheme 22-1 2-2R51-12-3 2-5Aryl halides 2-3, wherein R1, R2, R3, R4, and R5are as previously disclosed, may be treated with vinylbenzenes 2-4, wherein R6and R9are as previously disclosed, in the presence of a transition metal catalyst such as palladium(II) acetate and a bisphosphine ligand such as l, l'-bis(diphenylphosphino)ferrocene in a basic solvent such as triethylamine at temperatures from about 60 °C to about 100 °C to provide stilbenes 1-1 (Scheme 2, step b). Alternatively, Aryl halides 2-3 may be treated with vinylboronates 2-5, wherein R6and R9are as previously disclosed, in the presence of a transition metal catalyst such as tetrakis(triphenylphosphine)palladium(0) and a base such as potassium carbonate in a solvent mixture such as 1,2-dimethoxyethane and water at temperatures from about 60 °C to about 100 °C to provide stilbenes 1-1 (Scheme 2, step c).In yet another embodiment, stilbenes 1-1 may also be prepared by the Wittig olefination method (Chalal, M . ; Vervandier-Fasseur, D. ; Meunier, P. ; Cattey, H . ; Hierso, J .-C. Tetrahedron 2012, 68, 3899-3907) as outlined in Scheme 2.5. Phenyl carbonyls 2- 1, wherein R1, R2, R3, R4, and R5are as previously disclosed and R6is H, may be treated with alkoxy benzyl triphenylphosphonium chlorides 2.5-2 in the presence of a base such as n-butyl lithium in a polar aprotic solvent such as tetrahydrofuran at temperatures from about -78 °C to ambient temperature to provide stilbenes 1-120 (Scheme 2.5, step a).Scheme 2.5'(CrC4)alkyla2-1 2.5-2.0.(C1-C4)alkylPreparation of cyclopropyl amidesCyclopropyl amides 3-3, wherein R\ R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, X1, X2, and Q2are as previously disclosed, and X3is as previously disclosed and OH, may be prepared by treatment with amines or amine salts 3-2, wherein R10, R11, R12, X1, X2, Q2, and X3are as previously disclosed, and activated carboxylic acids 3-1, wherein A is an activating group, and R1, R2, R3, R4, Rs, R6, R7, R8, and R9are as previously disclosed, with a base, such as triethylamine, diisopropylethylamine, 4- methylmorpholine, 4-dimethylaminopyridine, or pyridine in an anhydrous aprotic solvent such as dichloromethane, tetrahydrofuran, 1, 2-dichloroethane, dimethylformamide, or any combination thereof, at temperatures between about 0 °C and about 120 °C (Scheme 3, step a).Activated carboxylic acids 3-1 may be an acid halide, such as an acid chloride, an acid bromide, or an acid fluoride; a carboxylic ester, such as a para-nitrophenyl ester, a pentafluorophenyl ester, an ethyl (hydroxyiminio)cyanoacetate ester, a methyl ester, an ethyl ester, a benzyl ester, an / V-hydroxysuccinimidyl ester, a hydroxybenzotriazol- l-yl ester, or a hydroxypyridyltriazol- l-yl ester; an O-acylisourea ; an acid anhydride ; or a thioester. Acid chlorides may be prepared from the corresponding carboxylic acids by treatment with a dehydrating chlorinating reagent, such as oxalyl chloride or thionyl chloride. Activated carboxylic esters 3-1 may be prepared from carboxylic acids in situ with a uronium salt, such as 1- [bis(dimethylamino)methylene]- lH- l,2,3-triazolo[4,5- b]pyridinium 3-oxid hexafluorophosphate (HATU), 0-(benzotriazol- l-yl)- / V / / V / V' / / V - tetramethyluronium hexafluorophosphate (HBTU), or ( l -cyano-2-ethoxy-2-25 oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate(COMU) . Activated carboxylic esters 3-1 may also be prepared from carboxylic acids insitu with a phosphonium salt such as benzotriazol-l-yl-oxytripyrrolidinophosphonium hexafluorophosphate (PyBop). Activated carboxylic esters 3-1 may also be prepared from carboxylic acids in situ with a coupling reagent such as l-(3-dimethylamino propyl)-3-ethylcarbodiimide, propylphosphonic anhydride, or dicyclohexylcarbodiimide with or without the presence of a triazole such as hydroxybenzotriazole^ monohydrate (HOBt) or l-hydroxy-7-azabenzotriazole (HOAt) . O-Acylisoureas may be prepared with a dehydrating carbodimide such as l-(3-dimethylamino propyl)-3-ethylcarbodiimide or dicyclohexylcarbodiimide. Activated carboxylic esters 3-1 may also be prepared from carboxylic acids in situ with a coupling reagent such as 2-chloro-l,3- dimethylimidazolidinium hexafluorophosphate (CIP) in the presence of a triazole such as l-hydroxy-7-azabenzotriazole (HOAt).Cyclopropyl amides 3-3 containing a sulfide may be oxidized to the corresponding sulfoxide or sulfone by treatment with about one equiva lent of meta- chloroperoxybenzoic acid (sulfoxide) in a polar aprotic solvent such as dichloromethane or about two equivalents of meta-chloroperoxybenzoic acid (sulfone) at temperatures between about 0 °C to about 40 °C. Alternatively, cyclopropyl amides 3-3 containing a sulfide may be oxidized to the corresponding sulfoxide or sulfone by treatment with one equivalent of sodium perborate in a protic solvent such as acetic acid (sulfoxide) or two equivalents of sodium perborate (sulfone). The oxidation may be performed at temperatures between about 40 °C to about 100 °C using about 1.5 equivalents of sodium perborate to provide chromatographically separable mixtures of sulfoxide and sulfone cyclopropyl amides 3-3. Alternatively, cyclopropyl amides 3-3 containing a sulfide may be oxidized to the corresponding sulfilimine by treating with about one equivalent of an amine such as cyanamide, about one equivalent of a base such as potassium ieri-butoxide, and between one and two equivalents of an oxidant such as N- bromosuccinimide in a polar protic solvent such as methanol at temperatures between about 0 °C to about 40 °C. The sulfilimine may be further oxidized to the corresponding sulfoximine by treatment with about one equivalent of meta-chloroperoxybenzoic acid and about two equivalents of potassium carbonate in a mixture of solvents such as 2 : 1 : 1 ethanol : dichloromethane: water at temperatures between about 0 °C to about 40 °C.Cyclopropyl amides 3-3, wherein X1, X2, X4, X5, X6, X7, or , X8is N may be oxidized to the corresponding / V-oxide by treatment with about one equivalent of m eta - chloroperoxybenzoic acid in a polar aprotic solvent such as dichloromethane at temperatures between about 0 °C to about 40 °C.Cyclopropyl amides 3-3, wherein R3is NO2may be reduced to the correspondingNH2by treatment with an acid source, such as ammonium chloride, and iron in a polar protic solvent, such as methanol, water, or any combination thereof, at temperatures from about 20 °C to about 60 °C.Amines or amine salts 3-2, wherein Q2is 0 may be treated directly with a source of sulfur, such as phosphorus pentasulfide or 2,4-bis(4-methoxyphenyl)-l,3,2,4- dithiadiphosphetane 2,4-disulfide (Lawesson's reagent) with or without additives such as 1, 1, 1,3,3,3-hexamethyldisoloxane, in an aprotic solvent chosen from tetrahydrofuran, dichloromethane, chloroform, toluene, or pyridine, at temperatures from about 40 °C to about 120 °C to provide amines or amine salts 3-2, wherein Q2is S.Scheme 33-2Cyclopropyl amides 4-3, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, and X3are as previously disclosed, may be prepared by treatment with amines or amine salts 4-2, wherein X3is as previously disclosed, and activated carboxylic acids 4-1, wherein A is an activating group, and R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, and X2are as previously disclosed, with a base, such as triethylamine, diisopropylethylamine, 4-methylmorpholine, 4-dimethylaminopyridine, or pyridine in an anhydrous aprotic solvent such as dichloromethane, tetrahydrofuran, 1,2- dichloroetha ne, dimethylformamide, or any combination thereof, at temperatures between about 0 °C and about 120 °C (Scheme 4, step a) .Activated carboxylic acids 4-1 may be an acid halide, such as an acid chloride, an acid bromide, or an acid fluoride; a carboxylic ester, such as a p-nitrophenyl ester, a pentafluorophenyl ester, an ethyl (hydroxyimino)cyanoacetate ester, a methyl ester, an ethyl ester, a benzyl ester, an / V-hydroxysuccinimidyl ester, a hydroxybenzotriazol- l-yl ester, or a hydroxypyridyltriazol- l-yl ester; an O-acylisourea ; an acid anhydride; or a thioester. Acid chlorides may be prepared from the corresponding carboxylic acids bytreatment with a dehydrating chlorinating reagent, such as oxalyl chloride or thionyl chloride. Activated carboxylic esters 4-1 may be prepared from carboxylic acids in situ with a uronium salt, such as 1- [bis(dimethylamino)methylene]- lH- l,2,3-triazolo[4,5- b]pyridinium 3-oxid hexafluorophosphate ( HATU), 0-(benzotriazol- l-yl )- / V / / V / / V' / / V'- tetramethyluronium hexafluorophosphate (HBTU), or ( l -cyano-2-ethoxy-2- oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate (COMU) . Activated carboxylic esters 4-1 may also be prepared from carboxylic acids in situ with a phosphonium salt such as benzotriazol- l -yl-oxytripyrrolidinophosphonium hexafluorophosphate ( PyBop). Activated carboxylic esters 4-1 may also be prepared from carboxylic acids in situ with a coupling reagent such as l -(3-dimethylamino propyl)-3-ethylcarbodiimide, propylphosphonic anhydride, or dicyclohexylcarbodiimide with or without the presence of a triazole such as hydroxybenzotriazole^ monohydrate (HOBt) or l-hydroxy-7-azabenzotriazole (HOAt) . O-Acylisoureas may be prepared with a dehydrating carbodimide such as l-(3-dimethylamino propyl)-3-ethylcarbodiimide or dicyclohexylcarbodiimide. Activated carboxylic esters 4-1 may also be prepared from carboxylic acids in situ with a coupling reagent such as 2-chloro- l,3- dimethylimidazolidinium hexafluorophosphate (CIP) in the presence of a triazole such as l-hydroxy-7-azabenzotriazole (HOAt).Scheme 4R12HX34-34-2Cyclopropyl amides 5-2, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R1S, X4, Xs, X6, X7, and X8are as previously disclosed, may be prepared by treatment of amines 5-1, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R15, X4, X5, X6, X7, and X8are as previously disclosed, with amethylating agent such as methylboronic acid and a copper catalyst such asdiacetoxycopper in the presence of an aprotic amine base like pyridine in a solvent such as 1,4-dioxane at a temperature of about 110 °C (Scheme 5, step a) .Cyclopropyl amides 5-4, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R1S, X4, Xs, X6, X7, and X8are as previously disclosed, and L is (G- C6)alkyl, (C2-C6)a lkenyl, (C3-C6)cycloalkyl, (G-G)haloalkyl, (C1-C6)alkylphenyl, and (G- C6)alkoxy, wherein each alkyl, alkenyl, cycloalkyl, haloa lkyl, and phenyl, may be optionally substituted with one or more substituents selected from F, CI, Br, I, CN, OH,NH2, NO2, oxo, (G-G)alkyl, (G-G)alkoxy, and C(0)0(G-Q)alkyl, may be prepared by treatment of amines 5-1, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R15, X4, X5, X6, X7, and X8are as previously disclosed, or amines 5-2, wherein R1, R2, R3, R4, Rs, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R1S, X4, Xs, X6, X7, and X8are as previously disclosed, and activated carboxylic acids 5-3, wherein A is an activating group, and L is as previously disclosed, with a base, such as triethylamine, diisopropylethylamine, 4-methylmorpholine, 4-dimethylaminopyridine, or pyridine, in an anhydrous aprotic solvent such as dichloromethane, tetrahydrofuran, 1,2- dichloroetha ne, Λ / , / V-dimethylformamide, or any combination thereof, at temperatures between about 0 °C and about 120 °C (Scheme 5, steps b and c).Activated carboxylic acids 5-3 may be an acid halide, such as an acid chloride, an acid bromide, or an acid fluoride; a carboxylic ester, such as a p-nitrophenyl ester, a pentafluorophenyl ester, an ethyl (hydroxyiminio)cyanoacetate ester, a methyl ester, an ethyl ester, a benzyl ester, an / V-hydroxysuccinimidyl ester, a hydroxybenzotriazol- l-yl ester, or a hydroxypyridyltriazol- l-yl ester; an O-acylisourea ; an acid anhydride; or a thioester. Acid chlorides may be prepared from the corresponding carboxylic acids by treatment with a dehydrating chlorinating reagent, such as oxalyl chloride or thionyl chloride. Activated carboxylic esters 5-3 may be prepared from carboxylic acids in situ with a uronium salt, such as l -[bis(dimethylamino)methylene]-lH-l,2,3-triazolo[4, 5- b]pyridinium 3-oxid hexafluorophosphate ( HATU), 0-(benzotriazol- l-yl)- / V / / V / A / , / / V'- tetramethyl uronium hexafluorophosphate (HBTU ), or ( l -cyano-2-ethoxy-2- oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate(COMU) . Activated carboxylic esters 5-3 may also be prepared from carboxylic acids in situ with a phosphonium salt such as benzotriazol- l -yl-oxytripyrrolidinophosphonium hexafluorophosphate (PyBop). Activated carboxylic esters 5-3 may also be prepared from carboxylic acids in situ with a coupling reagent, such as l-(3-dimethylamino propyl)-3-ethylcarbodiimide or dicyclohexylcarbodiimide, in the presence of a triazole such as hydroxybenzotriazole- monohydrate (HOBt) or l-hydroxy-7-azabenzotriazole (HOAt). O-Acylisoureas may be prepared with a dehydrating carbodimide such as l-(3- dimethylaminopropyl)-3-ethylcarbodiimide or dicyclohexylcarbodiimide. Activatedcarboxylic esters 5-3 may also be prepared from carboxylic acids in situ with a coupling reagent such as 2-chloro- l ,3-dimethylimidazolidinium hexafluorophosphate (CIP) in the presence of a triazolol such as l-hydroxy-7-azabenzotriazole ( HOAt) . Activated carboxylic esters 5-3 may also be prepared from carboxylic acids in situ with a coupling reagent such as 2,4,6-tripropyl-l,3,5,2,4,6-trioxatriphosphinane 2,4,6-trioxide (T3P,R) in the presence of a base such as pyridine.Scheme 5R12R2Cyclopropyl amides 6-3, wherein R\ R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R15, X5, X6, X7, and X8are as previously disclosed, may be prepared by treatment of aldehydes or ketones 6-1 wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R15, X5, X6, X7, and X8are as previously disclosed, and hydroxylamines 6-2, wherein each alkyl may be optionally substituted with one or more substituents selected from F, CI, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)a lkyl, (G- C6)alkoxy, and C(0)0(C1-C6)alkyl, with or without an acid, such as acetic acid, in a polaraprotic solvent such as ethanol, at temperatures between about 0 °C and about 80 (Scheme 6, step a).Scheme 6R126-3Cyclopropyl amides 7-3, wherein R\ R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R15, X4, X5, X7, and X8are as previously disclosed, may be prepared by treatment of aldehydes or ketones 7-1 wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R15, X4, X5, X7, and X8are as previously disclosed, and hydroxylamines 7-2, wherein each alkyl may be optionally substituted with one or more substituents selected from F, CI , Br, I , CN , OH , NH2, N Oz, oxo, ( Ci -Ce)a lkyl, (G-Ce)alkoxy, and C(0)0(C1-C6)alkyl, with or without an acid, such as acetic acid, in a polar aprotic solvent such as ethanol, at temperatures between about 0 °C and about 80 °C (Scheme 7, step a) .Scheme 7> 127-3Cyclopropyl amides 8-3, wherein R\ R2, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, X3, and Q2are as previously disclosed, may be prepared by treatment of aryl bromide 8-1, wherein R1, R2, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, X3, and Q2are as previously disclosed, and (C1-C6)alkenyl or (C1-C6)a lkynyl stannane 8-2, wherein each alkenyl or alkynyl group may be optionally substituted with one or more substituents selected from F and SiMes, with a palladium source, such asbis(triphenylphosphine)palladium(II) dichloride in an aprotic solvent such as 1,4- dioxane, at temperatures between about 20 °C and about 120 °C (Scheme 8, step a) .Cyclopropyl amides 8-3 , wherein (C1-C6)alkynyl is trimethylsilyl alkyne may be treated with a source of fluoride, such as potassium fluoride, in a polar solvent, such as dichloromethane, methanol, or a combination thereof, at temperatures from about 0 °C to about 50 °C to provide cyclopropyl amide 8-3, wherein (C1-C6)alkynyl is CCH.Scheme 8-C6) alkenyl,(C1- C6)alkynyl8-2Bra R12(C1- C6)alkenyl,(C1- C6)alkynylCyclopropyl amides 9-3 , wherein R1, R2, R3, Rs, R6, R7, R8, R9, Q R10, R R12, X1, X2, X3, and Q2are as previously disclosed, may be prepared by treatment of aryl bromide 9-1, wherein R1, R2, R3, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, X3, and Q2are as previously disclosed, and (C1-C6)alkenyl or ( C1-C6)a lkynyl stannane 9-2, wherein each alkenyl or alkynyl group may be optionally substituted with one or more substituents selected from F and SiMes, with a palladium source, such asbis(triphenylphosphine)palladium(II) dichloride in an aprotic solvent such as 1,4- dioxane, at temperatures between about 20 °C and about 120 °C (Scheme 9, step a) .Cyclopropyl amides 9-3, wherein (C1-C6)alkynyl is trimethylsilyl alkyne may be treated with a source of fluoride, such as potassium fluoride, in a polar solvent, such as dichloromethane, methanol, or a combination thereof, at temperatures from about 0 °C to about 50 °C to provide cyclopropyl amide 9-3, wherein ( C1-C6)alkynyl is CCH.Scheme 9(C C6) alkenyl,(CrC6)alkynylBr-9-2a R12-C6)alkenyl,(C1- C6)alkynylCyclopropyl amides 10-3, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, X4, X5, X6, X7, and X8are as previously disclosed, may be prepared by treatment of primary amides 10-1, wherein R1, R2, R3, R4, Rs, R6, R7, R8, R9, Q1, R10, R11, R12, X1, and X2are as previously disclosed, and aryl bromides 10-2, wherein X4, X5, X6, X7, and X8are as previously disclosed, with a palladium catalyst such as tris(dibenzy!ideneacetone)dipal!adium(0), a phosphine ligand such as 4,5- Bis(diphenylphosphino)-9,9-dimethylxa nthene, and an inorganic base such as cesium carbonate, in an aprotic solvent such as 1,4-dioxane, at temperatures between about 60 °C and about 80 °C (Scheme 10, step a).Scheme 10> 1210-2Cyclopropyl amides 11-3, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, X4, X5, X6, X7, and X8are as previously disclosed, may be prepared by treatment of 11-1, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2,X4, X5, X6, X7, and X8are as previously disclosed, with a metal such as palladium on carbon in the presence of a reducing agent such as hydrogen gas in a solvent such as ethyl acetate or with a metal such as iron in the presence of a reducing agent such as ammonium chloride in a solvent mixture such as methanol and water at a temperature of about 25 °C to about 60 °C (Scheme 11, step a). Alternatively, cyclopropyl amides 11-3, wherein R\ R2, R3, R4, R5, R6, R7, R8, R9, Q\ R10, R11, R12, X1, X2, X4, X5, X6, X7, and X8are as previously disclosed, may be prepared by treatment of 11-2 wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q\ R10, R11, R12, X1, X2, X4, X5, X6, X7, and X8are as previously disclosed, with an anhydrous acid solution such as hydrochloric acid in 1,4- dioxane and dichloromethane at a temperature of about 25 °C (Scheme 11, step b).Scheme 11R12Cyclopropyl amides 12-3, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, R10, R11, R12, X1, X2, Q2, R1S, X4, Xs, X6, X7, and X8are as previously disclosed and L2is a (C1-C6)alkenyl or (C1-C6)alkynyl group, wherein each alkenyl or alkynyl group may be optionally substituted with one or more substituents selected from F, CI, and (G- C6)alkyl, may be prepared by treatment of aryl halides 12-1, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Ql, R10, R", R12, X1, X2, Q2, R15, X4, X5, X6, X7, and X8are as previously disclosed, with a stannane such as 12-2, wherein L2is as previously disclosed, in the presence of a metal catalyst such asbis(triphenylphosphine)palladium(II) dichloride in a n aprotic solvent like 1,4-dioxane at a temperature of about 90 °C (Scheme 12, step a).Scheme 12R12In some embodiments, 1-3 may be prepared from the αβ-unsaturated aldehyde 13-1, wherein R1, R2, R3, R4, R5, R6, and R9are as previously. It will be understood by one skilled in the art that compound 13-1 may be synthesized via Aldol condensation (see Yoshikawa, M . ; Kamei, T. PCT Int. Appl. 2010123006, 2010) of an appropriately substituted, commercially available aldehyde and acetaldehyde. Treatment of 13-1 with a (C1-C6)alkyl orthoformate, in the presence of an acid whose pH is 0-5 such as hydrobromic acid, / V-bromosuccinimide, hydrochloric acid, / V-chlorosuccinimide, and pyridinium p-toluenesulfonate (PPTS), in a (C1-C6)alkanol solvent, at a temperature from 0 °C to ambient and under ambient pressure provides the acetal 13-2, wherein R1, R2, R3, R4, R5, R6, and R9are as previously disclosed and Rais a (Ci-C6)a lkyl or Raand Rataken together can form a cyclic acetal (Scheme 13, step a). The acetal 13-2 may be converted to the cyclopropyl acetal 13-3, wherein Rl, R2, R3, R4, R5, R6, R7, R8, R9, and Raare as previously disclosed, by treatment with a carbene source such as a haloform, for example, bromoform or chloroform, in the presence of an inorganic base, such as sodium or potassium hydroxide or sodium or potassium carbonate, and a phase- transfer catalyst such as benzyl triethylammonium chloride, ( -)- / V-dodecyl- / V- methylephedrinium bromide, tetramethylammonium bromide, tetrapropylammonium20 bromide, tetrabutylammonium tetrafluoroborate, tetramethylammonium chloride or tetrabutylammonium hexafluorophosphate at a temperature from about ambienttemperature up to below the boiling point of the haloform (Scheme 13, step b). Caution : Step B is an exothermic reaction and careful control of the exotherm should be exercised when conducting this reaction. The cyclopropyl acetal 13-3 may be transformed into the aldehyde 13-4, wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9are as previously disclosed, in a polar solvent selected from the group consisting of acetone, acetonitrile, methanol, ethanol, nitromethane, Λ / , / V-dimethylformamide, dimethyl sulfoxide, ethyl acetate, tetrahydrofuran and 1 ,4-dioxane, in the presence of an aqueous mineral acid selected from the group consisting of nitric acid, hydrochloric acid, hydrobromic acid, and sulfuric acid (Scheme 5, step c) at ambient temperature. The cyclopropyl acid 1-3, wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9are as previously disclosed, may be obtained by oxidation of the aldehyde 13-4 with oxidants such sodium permanganate or potassium permanganate, or under Pinnick oxidation conditions in a polar aprotic solvent selected from the group consisting of acetone, acetonitrile, / V / W-dimethylformamide, dimethyl sulfoxide, ethyl acetate, tetrahydrofuran and 1,4-dioxane at a temperature from about 0 °C to about ambient temperature (Scheme 13, step d) . Standard safety precautions should be exercised because an exotherm may occur when conducting this reaction.Scheme 13R21-3It will be understood by those skilled in the art that, in some embodiments, the cyclopropyl acid 1-3, wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9are as previouslydisclosed, may be resolved into its (R,R) and (S,S) enantiomers via a method such as that in Kovalenko V. N . , Kulinkovich 0. G. Tetrahedron: Asymmetry 2011, 22, 26 (Scheme 14, step a).Scheme 14ExamplesThese examples are for illustration purposes and are not to be construed as limiting this disclosure to only the embodiments disclosed in these examples.Starting materials, reagents, and solvents that were obtained from commercial sources were used without further purification. Anhydrous solvents were purchased as Sure / Seal™ from Aldrich and were used as received . Melting points were obtained on a Thomas Hoover Unimelt capillary melting point apparatus or an OptiMelt Automated Melting Point System from Stanford Research Systems and are uncorrected . Examples using " room temperature" were conducted in climate controlled laboratories with temperatures ranging from about 20 °C to about 24CC. Molecules are given their known names, named according to naming programs within ISIS Draw, ChemDraw, or ACD Name Pro. If such programs are unable to name a molecule, such molecule is named using conventional naming rules. Ή NM R spectral data are in ppm (δ) and were recorded at 300, 400, 500, or 600 MHz;13C NMR spectral data are in ppm (δ) and were recorded at 75, 100, or 150 MHz, and19F NM R spectral data are in ppm (δ) and were recorded at 376 MHz, unless otherwise stated.Example 1 : Preparation of trans-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropanecarboxylic acid (CI )CIRuthenium(III) chloride (0.080 g, 0.39 mmol) was added to a stirred mixture of frans- l,3-dichloro-5-(-2,2-dichloro-3-(4-methoxyphenyl)cyclopropyl)benzene (C22) (2.8 g, 7.7 mmol) and sodium periodate (33 g, 160 mmol) in waten ethylacetate iacetonitrile (8 : 1 : 1, 155 mL) at 23 °C. The resulting biphasic brown mixture was vigorously stirred at 23 °C for 5 hours. The reaction mixture was diluted with water ( 1000 mL) and extracted with dichloromethane (4 x 200 mL) . The combined organic layers were dried over magnesium sulfate, filtered, and concentrated. The residue was diluted with a sodium hydroxide solution ( 1 M, 100 mL) and washed with diethyl ether (4 x 50 mL). The aqueous layer was adjusted to pH 2, using concentrated hydrochloric acid, and extracted with dichloromethane (3 x 50 mL) . The combined organic layers were dried over magnesium sulfate, filtered, and concentrated to afford the title product as a light brown powder (0.78 g, 34%) : mp 117 - 120 °C; Ή N R (400 MHz, DMSO-de) δ 13.38 (br s, 1 H), 7.52 - 7.65 ( m, 3H), 3.57 (d, J = 8.5 Hz, 1H ), 3.50 (d, J = 8.5 Hz, 1 H) ; IR (thin film) 3083 (s), 3011 (s), 1731 (s), 1590 (w), 1566 (s), 1448 (w), 1431 (m), 1416 (m) cm1.The following compounds were prepared in like manner to the procedure outlined in Example 1 :trans-2, 2-Dichloro-3-(3,4,5-trichlorophenyl )cyclopropanecarboxylic acid (C2)OH crCIIsolated as a yellow powder ( 1.5 g, 39%) :lH NM R (400 MHz, CDCb) δ 7.31 (d, J = 0.7 Hz, 2H), 3.40 (d, J = 8.2 Hz, 1H), 2.86 (d, J = 8.3 Hz, 1H) ;13C N MR ( 101 MHz, CDCb) δ 171.05, 134.55, 132.44, 131.75, 128.89, 61.18, 39.26, 37.14; ESIMS m / z 333 ( [M-H]-).trans-2, 2-Dichloro-3-(3,4-dlchlorophenyl )cyclopropanecarboxylic acid (C3)Isolated as a pale yellow solid (3.2 g, 51%) : Ή NMR (400 MHz, CDC ) δ 7.47 (d, J = 8.3 Hz, 1H), 7.37 (d, J = 1.6 Hz, 1H), 7.12 (ddd, J = 8.3, 2. 1, 0.6 Hz, 1H), 3.43 (d, J = 8.3 Hz, 1H), 2.86 (d, J = 8.3 Hz, 1H ) ;13C NMR ( 101 MHz, CDCIs) δ 171.52, 132.91, 132.76, 132.29, 130.66, 130.62, 128.02, 61.48, 39.65, 37.13; ESIMS m / z 298 ( [M-H]'). Example 2: Preparation of trans-2,2-dichloro-3-(4- (trifluoromethyl )phenyl )cyclopropanecarboxylic acid (C4)To a stirred mixture of trans-l-(2,2-dichloro-3-(4- (trifluoromethyl)phenyl)cyclopropyl)-4-methoxybenzene (C25) (3.50 g, 9.60 mmol) and sodium periodate (30.8 g, 144 mmol) in waten ethyl acetate :acetonitrile (8 : 1 : 1, 200 mL) was added ruthenium(III) chloride (0.100 g, 0.400 mmol) at 23 °C. The resulting mixture was vigorously stirred at 23 °C for about 5 hours. The reaction mixture was diluted with dichloromethane and washed with water. The combined organic layers were dried over sodium sulfate, filtered, and concentrated . Purification by flash column chromatography provided the title compound as an off-white solid (0.630 g, 38%) : mp 100 - 102 °C; Ή NM R (400 MHz, DMSO- / e) δ 13.43 (brs, 1H), 7.77 - 7.73 (m, 2H ), 7.67 - 7.64 ( m, 2H), 3.55 (d, J = 8.8 Hz, 1H), 3.44 (d, J = 8.8 Hz, 1H) ; ESIMS m / z 347 ( [M-H]-).The following compounds were prepared in like manner to the procedure outlined in Example 2 :trans-2,2-Dichloro-3-(3-(trlfluoromethyl )phenyl )cyclopropanecarboxylic acid (C5)CI CIFIsolated as an off-white solid (0.81 g, 33%): mp 86 - 88 °C; Ή NMR (400 MHz, DMSO-de) δ 13.37 (brs, 1H), 7.83 (s, 1H), 7.76 - 7.69 (m, 2H), 7.65 - 7.59 (m, 1H), 3.59 - 3.51 (m, 2H); ESIMS m / z 297 ([M-H] ).trans-2, 2-Dichloro-3-(3-chloro-4- (trifluoromethoxy)phenyl)cyclopropanecarboxylic acid (C6)Isolated as an off-white solid (0.3 g, 19%): mp 134 - 136 °C; Ή NMR (400 MHz, DMSO-de) δ 13.45 (brs, 1H), 7.82 (d, J = 1.6 Hz, 1H), 7.60 - 7.53 (m, 2H), 3.53 - 3.47 (m, 2H); ESIMS m / z 347 ([M-H]").trans-2,2-Dichloro-3-(2,4,5-trlchlorophenyl)cyclopropanecarboxylic acid (C7)CI CI nIsolated as an off-white solid (0.267 g, 18%): mp 189 - 192 °C; *H NMR (400 MHz, DMSO-c / e) δ 13.44 (brs, 1H), 8.01 (s, 1H), 7.82 (s, 1H), 3.52 (d, J = 8.2 Hz, 1H), 3.29 (d, 3 = 8.2 Hz, 1H); ESIMS m / z 333 ([M-H] ).trans-3-(3,5-bis(trif1uoromethyl)phenyl)-2,2-dichlorocyclopropanecarboxylic acid (C8)CI CI 0FIsolated as an off-white solid (0.5 g, 31%): mp 112 - 114 °C; 'H NMR (400 MHz DMSO-cie) δ 13.43 (brs, 1H), 8.22 (s, 2H), 8.08 (s, 1H), 3.80 - 3.71 (m, 2H); ESIMS m / z 365 ([M-H]').trans-2, 2-dichloro-3-(3,5-dibromophenyl)cyclopropanecarboxylic acid (C9)BrIsolated as an off-white solid (0.5 g, 24%): mp 157 - 159 °C; Ή NMR (400 MHz, DMSO-tfe) δ 13.36 (brs, 1H), 7.81 (d, J = 1.5 Hz, 2H), 7.72 (d, J = 1.5 Hz, 2H), 3.57 - 3.53 (m, 1H), 3.51 - 3.47 (m, 1H); ESIMS m / z 387 ([M-H]').trans-2,2-Dichloro-3-(3-chloro-5-(trifluoromethyl)phenyl)cyclopropanecarboxylic acid (CIO)CIIsolated as an off-white solid (0.73 g, 28%): mp 113 - 115 °C; Ή NMR (400 MHz, DMSO- / e) δ 13.39 (brs, 1H), 7.91 (s, 1H), 7.86 (s, 1H), 7.84 (s, 1H), 3.69 - 3.60 (m, 2H); ESIMS m / z 333 ([M-H] ).trans-2, 2-Dichloro-3-(3,5-dichloro-4-fluorophenyl)cyclopropanecarboxylic acid (Cll)CIIsolated as an off-white solid (0.539 g, 34%): Ή NMR (400 MHz, DMSO-de): δ 13.37 (brs, 1H), 7.71 (d, J = 6.4 Hz, 2H), 3.42 (s, 2H); ESIMS m / z 317 ([M-H]').trans-3-(4-Bromo-3,5-dichlorophenyl)-2,2-dichlorocyclopropanecarboxylic acid (C12)Isolated as an off-white solid (0.100 g, 10%): Ή N R (400MHz, DMSO-ck) δ 13.37 (brs, 1H), 7.76 (s, 3H), 3.57 (d, J = 8.8 Hz, 1H), 3.48 (d, J = 8.8 Hz, 1H); ESIMS m / z 377 ([M-H]-).trans-3-(3-Bromo-5-chlorophenyl)-2,2-dichlorocyclopropanecarboxylic acid (C13)CIIsolated as an off-white solid (0.4 g, 25%): mp 161 - 163 °C; »H NMR (400MHz, DMSO- / e) δ 13.38 (br s, 1H), 7.70 (d, J = 5.3 Hz, 2H), 7.66 - 7.52 (m, 1H), 3.59 - 3.4 (m, 2H); ESIMS m / z 341 ([M-H]-).trans-2, 2-Dichloro-3-(3-chloro-5-f1uorophenyl)cyclopropanecarboxylic acid (C14)CIIsolated as an off-white solid (0.700 g, 25%): mp 138 - 140 °C; Ή NMR(400MHz, DMSO-de) δ 13.38 (brs, 1H), 7.46 (s, 1H), 7.42 (td, J = 2.0, 8.7 Hz, 1H), 7.37 (d, J = 9.8 Hz, 1H), 3.52 (q, J = 8.5 Hz, 2H); ESIMS m / z 281 ([M-H]").frans-2,2-Dichloro-3-(4-chloro-3-f1uorophenyl)cyclopropanecarboxylic acid (C15)Isolated as an off-white solid (0.500 g, 20%): mp 140 - 142 °C; >H NMR(400MHz, DMSO- / e) δ 13.40 (brs, 1H), 7.59 (m, 1H), 7.55 (d, J = 8.4 Hz, 1H), 7.33 (dd, J = 2.0, 8.4 Hz, 1H), 3.55 - 3.38 (m, 2H); ESIMS m / z 281 ([M-H] ).trans-2, 2-Dichloro-3-(3-chloro-4-fluorophenyl)cyclopropanecarboxylic acid (C16)Isolated as an off-white solid (1.0 g, 53%): mp 121 - 123 °C; Ή NMR (400 MHz, DMSO-de) δ 13.35 (brs, 1H), 7.71 (dd, J = 2.0, 7.2 Hz, 1H), 7.53 - 7.35 (m, 2H), 3.50 - 3.41 (m, 2H); ESIMS m / z 281 ([M-H] ).trans-2, 2-Dichloro-3-(3-chloro-5-methyl phenyl )cyclopropanecarboxylic acid (C17)CH3Isolated as an off-white solid (1.0 g, 42%): mp 124 - 126 °C; Ή NMR (400 MHz, DMSO- / e) δ 13.33 (brs, 1H), 7.30 (s, 1H), 7.23 (s, 1H), 7.21 (s, 1H), 3.38 (s, 2H), 2.31 (s, 3H); ESIMS m / z 277 ([M-H] ).trans-2, 2-Dichloro-3-(3,5-dichloro-4-methyl phenyl )cyclopropanecarboxylic acid (C18)Isolated as an off-white solid (0.8 g, 40%): mp 181 - 183 °C; Ή NMR (400 MHz, DMSO-de) δ 13.40 (s, 1H), 7.56 (s, 2H), 3.53 - 3.50 (m, 1H), 3.46 - 3.43 (m, 1H), 2.40 (s, 3H); ESIMS m / z 311 ([M-H]").frans-2,2-Dichloro-3-(3,4-dichloro-5-methylphenyl)cyclopropanecarboxylic acid (C19)Isolated as an off-white solid (0.73 g, 45%) : mp 157 - 159 °C; Ή N R (400 MHz, DMSO-de) δ 13.40 (s, 1H), 7.59 (d, J = 2.0 Hz, 1 H), 7.44 (d, J = 1.6 Hz, 1H), 3.43 (q, J = 8.5 Hz, 2H ), 2.39 (s, 3H) ; ESIMS m / z 311 ( [M-H ] ).trans-2, 2-Dichloro-3-(4-( perfluoroethyl )phenvl )cyclopropanecarboxylic acid (C20)CI CIOHIsolated as an off-white solid (0.020 g, 10%) : mp 116 - 118 °C; » H N MR (300 MHz, CDCb) δ 7.63 (d, J = 8.1 Hz, 2H), 7.42 (d, J = 8.1 Hz, 2H), 3.53 (d, J = 8.4 Hz, 1H), 2.94 (d, J = 8.4 Hz, 1H) ; ESIMS m / z 347 ( [M-H ]-).trans-2, 2-dichloro-3-(4-ethoxyphenyl )cyclopropanecarboxyl ic acid (C21 )H3C OIsolated as an off-white solid (0.025 g, 5%) : mp 129 - 130 °C; 'H NM R (400 MHz, CDCb) δ 7.16 (d, J = 8.4 Hz, 2H), 6.88 (d, J = 8.31 Hz, 2H), 4.03 (q, J = 6.8 Hz, 2H), 3.41 (d, J = 8.0 Hz, 1H), 2.81 (d, J = 8.0 Hz, 1H), 1.41 (t, J = 6.8 Hz, 3H) ; ESIMS m / z 273 ( [M-H]").Example 3: Preparation of trans-l,3-dlchloro-5-(2,2-dichloro-3-(4- methoxyphenyl )cyclopropyl )benzene (C22)Aqueous sodium hydroxide (50%, 6.8 ml_, 130 mmol) was added to a stirred solution of (E)- l, 3-dichloro-5-(4-methoxystyryl)benzene (C43) (2.4 g, 8.6 mmol) and / V-benzyl- / V,A / -diethylethanaminium chloride (0.20 g, 0.86 mmol) in chloroform ( 14 ml_, 170 mmol) at 23 °C. The resulting biphasic, dark brown mixture was vigorously stirred at 23 °C for 24 hours. The reaction mixture was diluted with water (200 ml_) and extracted with dichloromethane (2 x 100 mL). The combined organic layers were dried25 over magnesium sulfate, filtered, and concentrated to afford the title product as a brownoil (2.8 g, 90%) : »H N R (400 MHz, CDCb) δ 7.34 (t, J = 1.8 Hz, 1H), 7.21 - 7.30 (m, 4H), 6.93 (m, 2H), 3.83 (s, 3H), 3.14 (d, J = 8.5 Hz, 1H), 3.08 (d, J = 8.5 Hz, 1H) ; IR (thin film) 3075 (w), 2934 (w), 2836 (w ), 1724 (w), 1640 (w), 1609 (m), 1584 (m), 1568 (s), 1513 (s) cm1.The following compounds were prepared in like manner to the procedure outlined in Example 3 :trans-l,2,3-Trichloro-5-(2,2-dichloro-3-(4-methoxyphenvl )cyclopropyl )benzene (C23)Isolated as a dark foam (4.7 g, 100%) : *H NM R (400 MHz, CDCb) δ 7.40 (d, J =0.6 Hz, 2H), 7.29 - 7.22 (m, 2H), 6.96 - 6.89 (m, 2H), 3.83 (s, 3H), 3. 12 (d, J = 8.8 Hz, 1H), 3.06 (d, J = 8.7 Hz, 1 H) ;13C NMR ( 101 MHz, CDCb) δ 159.46, 135.08, 134.23, 130.91, 129.85, 129.16, 125.42, 114.02, 64.67, 55.32, 39.62, 38.48.trans-1, 2-Dichloro-4-( 2, 2-dichloro-3-(4-methoxy phenyl )cyclopropyl )benzene (C24)Isolated as an orange-red oil (7.6 g, 99%) : Ή NM R (400 MHz, CDCb) δ 7.47 (d, J = 4.9 Hz, 1H), 7.45 (bs, 1H), 7.30 - 7.23 (m, 2H), 7.21 (dd, J = 8.2, 1.9 Hz, 1H), 6.96 - 6.90 (m, 2H), 3.83 (s, 3H), 3.11 (app. q, J = 8.8 Hz, 2H) ;13C NMR ( 101 MHz, CDCb) δ 159.39, 134.90, 132.62, 131.99, 130.90, 130.40, 129.90, 128.33, 125.81, 113.98, 64.94, 55.33, 39.52, 38.75.Example 4: Preparation of trans-l-( 2,2-dichloro-3-(4- (trifluoromethyl )phenyl )cyclopropyl )-4-methoxybenzene (C25)To a stirred solution of (f)-l-methoxy-4-(4-(trifluoromethyl)styryl)benzene(C46) (4.00 g, 14.0 mmol) and / V-benzyl- / V, / V-diethylethanaminium chloride (0.320 g, 14.0 mmol ) in chloroform (23.1 g, 288 mmol), was added aqueous sodium hydroxide (50%, 8.64 g, 216 mmol) in water ( 17 ml.) at 23 °C, and the resulting mixture was vigorously stirred at 23 °C for 16 hours. The reaction mixture was diluted with water and extracted with dichloromethane. The combined organic layers were dried over sodium sulfate, filtered, and concentrated . Purification by flash column chromatography provided the title compound as an off-white solid (3.70 g, 68%) : Ή NM R (300 M Hz, CDCb) δ 7.65 (d, J = 8.4 Hz, 2H ), 7.49 (d, J = 8.4 Hz, 2H), 7.29 (d, J = 8.4 Hz, 2H), 6.94 (d, J = 8.4 Hz, 2H), 3.83 (s, 3H ), 3.19 (s, 2H) ; ESIMS m / z 361 ( [M + H ]+).The following compounds were prepared in like manner to the procedure outlined in Example 4 :trans- 1-( 2, 2-Dichloro-3-(4-methoxyphenyl )cyclopropyl )-3- (trifluoromethyl )benzene (C26)Isolated as a brown liquid (3.5 g, 67%) : Ή NM R (300 MHz, CDCb) δ 7.62 - 7.50 (m, 4H), 7.29 (d, J = 9.0 Hz, 2H), 6.94 (d, J = 9.0 Hz, 2H), 7.35 - 7.25 ( m, 3H), 7.97 - 6.88 (m, 1H), 3.83 (s, 3H), 3.19 (m, 2H) ; ESIMS m / z 361 ( [M + H ]+).trans-2-Chloro-4-( 2,2-dichloro-3-(4-methoxyphenyl )cyclopropyl )-l- (trifluoromethoxy)benzene (C27)OIsolated as an off-white solid (2.5 g, 65%) : 'H NM R (400 MHz, CDCb) δ 7.57 (d, J = 2.0 Hz, 1H), 7.44 (d, J = 8.8 Hz, 1H), 7.35 - 7.25 (m, 3H), 7.97 - 6.88 (m, 1H), 3.84 (s, 3H), 3.15 - 3.05 (m, 2H) ; ESIMS m / z 411 ( [M + H]+).trans-l,2,4-Trichloro-5-(2,2-dichloro-3-(4-methoxyphenyl )cyclopropyl )benzene(C28)0CH3CICI CIIsolated as a brown liquid (2.0 g, 58%): EIMS m / z 394 ([M]+).trans-l-( 2, 2-Dichloro-3-(4-methoxyphenyl)cyclopropyl)-3, 5- bis(trifluoromethyl)benzene (C29)F FFIsolated as a brown liquid (3.0 g, 61%): EIMS m / z 428 ([M]+).trans-l,3-Dibromo-5-(2,2-dlchloro-3-(4-methoxyphenyl)cyclopropyl)benzene(C30)BrIsolated as a brown liquid (3.0 g, 57%): Ή NMR (300 MHz, CDC ) δ 7.64 (s, 1H), 7.45 (s, 2H), 7.25 (d, J = 9.0 Hz, 2H), 6.92 (d, J = 9.0 Hz, 1H), 3.83 (s, 3H), 3.15 - 3.05 (m, 2H); ESIMS m / z 453 ([M + H]+),trans- l-Chloro-3-(2,2-dlchloro-3-(4-methoxyphenyl)cyclopropyl)-5- (trifluoromethyl)benzene (C31)CIIsolated as a brown solid (4.0g, 74%): Ή NMR (300 MHz, CDCb) δ 7.64 (s, 1H), 7.45 (s, 1H), 7.42 (s, 1H), 7.26 (d, J = 9.0 Hz, 2H), 6.93 (d, J = 9.0 Hz, 1H), 3.83 (s, 3H), 3.15 - 3.05 (m, 2H); ESIMS m / z 395 ([M + H]+).trans-1, 3-Dichloro-5-( 2, 2-dlchloro-3-(4-methoxyphenyl)cyclopropyl)-2- fluorobenzene (C32)Isolated as a brown solid (1.6 g, 54%): Ή NMR (300 MHz, CDCb) δ 7.32 (d, J = 6.0 Hz, 2H), 7.30 (d, J = 9.0 Hz, 1H), 6.93 (d, J = 9.0 Hz, 1H), 3.83 (s, 3H), 3.12 - 3.05 (m, 2H); ESIMS m / z 297 ([M + H]+),trans-2-Bromo-l,3-dichloro-5-(2,2-dichloro-3-(4- methoxyphenyl )cyclopropyl )benzene (C33)Isolated as an off-white solid (1.5 g, 44%): Ή NMR (300 MHz, CDCb) δ 7.36 (d, J = 9.0 Hz, 2H), 7.20 (s, 2H), 6.93 (d, J = 9.0 Hz, 2H), 3.83 (s, 3H), 3.15 - 3.05 (m, 2H); ESIMS m / z 439 ([M + H]+).trans-l-Bromo-3-chloro-5-(2,2-dichloro-3-(4- methoxyphenyl )cyclopropyl )benzene (C34)BrIsolated as an off-white solid (2.5 g, 50%): Ή NMR (400 MHz, CDCb) δ 7.49 (s, 1H), 7.30 (s, 1H), 7.28 - 7.24 (m, 3H), 6.92 (d, J = 8.0 Hz, 2H), 3.92 (s, 3H), 3.01 (q, J = 8.8 Hz, 2H); ESIMS m / z 405 ([M + H]+).trans- l-Chloro-3-(2,2-dichloro-3-(4-methoxyphenyl)cyclopropyl)-5- fluorobenzene (C35)CIIsolated as a brown liquid (3.5 g, 67%): ESIMS m / z 345 ([M+H]+).trans-l-Chloro-4-(2,2-dichloro-3-(4-methoxyphenyl)cyclopropvl)-2- fluorobenzene (C36)Isolated as an off-white solid (2.5 g, 65%): ESIMS m / z 345 ([M + H]+).trans-2-Chloro-4-(2,2-dlchloro-3-(4-methoxyphenyl)cyclopropyl)-l- fluorobenzene (C37)CIFIsolated as a brown liquid (2.0 g, 58%): ESIMS m / z 345 ([M + H]+).trans-l-Chloro-3-(2,2-dichloro-3-(4-methoxyphenyl)cyclopropyl)-5- methyl benzene (C38)CH3Isolated as an off-white solid (3.0 g, 47%): Ή NMR (400 MHz, CDC ) δ 7.27 (d, J = 8.8 Hz, 2H), 7.14 (s, 2H), 7.06 (s, 1H), 6.92 (d, J = 8.8 Hz, 2H), 3.82 (s, 3H), 3.10 (q, J = 8.8 Hz, 2H), 2.36 (s, 3H); ESIMS m / z 341 ([M + H]+).trans- l,3-Dichloro-5-( 2, 2-dichloro-3-(4-methoxyphenyl )cyclopropyl)-2- methyl benzene (C39)Isolated as a brown liquid (2.5 g, 80%): Ή NMR (400 MHz, CDCb) δ 7.25 (d, J = 8.0 Hz, 2H), 7.17 (d, J = 8.8 Hz, 1H), 6.92 (d, J = 8.0 Hz, 2H), 6.88 (d, J = 8.8 Hz, 1H), 3.82 (s, 3H),3.12 - 3.03 (m, 2H), 2.47 (s, 3H); ESIMS m / z 375 ([M + H]+).trans-l,2-Dichloro-5-(2,2-dlchloro-3-(4-methoxyphenyl)cvclopropyl)-3- methyl benzene (C40)CH3Isolated as a Brown liquid (4.0 g, 90%): ESIMS m / z 375 ([M + H]+).trans-l-(2,2-Dichloro-3-(4-(perfluoroethyl )phenyl )cyclopropyl )-4- methoxybenzene (C41)Isolated as an off-white solid (0.5 g, 46%): Ή NMR (400 MHz, CDCb) δ 7.60 - 7.50 (m, 4H), 7.47 (d, J = 8.0 Hz, 2H), 6.92 (d, J = 8.0 Hz, 2H), 3.82 (s, 3H), 3.20 (s 2H); ESIMS m / z 411 ([M + H]+).trans-4,4'-(3,3-Dichlorocyclopropane-l,2-diyl)bis(ethoxybenzene) (C42)Isolated as an off-white solid (1.5 g, 45%): Ή NMR (400 MHz, CDCb) δ 7.27 (d, J = 8.0 Hz, 4H), 6.90 (d, J = 8.0 Hz, 4H), 4.04 (q, J = 6.8 Hz, 4H), 3.09 (s, 2H), 1.42 (t, J = 6.8 Hz, 6H); ESIMS m / z 351 ([M + H]+).Example 5: Preparation of (£)-l,3-dichloro-5-(4-methoxystyryl )benzene (C43)CISodium methoxide powder (98%, 0.63 g, 11 mmol) was added to a stirred solution of 3,5-dichlorobenzaldehyde (2.0 g, 11 mmol) a nd diethyl 4- methoxybenzylphosphonate (2.0 mL, 11 mmol) in dry / V, V-dimethylformamide (38 ml_) at 23 °C. The resulting heterogeneous dark blue mixture was heated to 80 °C, resulting in a dark brown mixture, and stirred for 24 hours. The cooled reaction mixture was diluted with water (500 mL) and extracted with diethyl ether (3 x 100 mL) . The combined organic layers were diluted with hexane ( 150 mL) and washed with water (300 mL) . The organic layer was dried over magnesium sulfate, filtered, and concentrated to afford the title product as a light brown oil (2.4 g, 75%) : 'H NM R (400 MHz, CDCb) δ 7.44 (m, 2H), 7.34 (d, J = 2 Hz, 2H ), 7.20 (t, J = 2 Hz, 1H), 7.06 (d, J = 16.5 Hz, 1H), 6.91 (m, 2H), 6.82 (d, J = 16.5 Hz, 1H), 3.84 (s, 3H) ; IR (thin film) 2934 (w), 2835 (w), 1724 (w), 1637 (w), 1605 (m), 1581 (m), 1558 (m), 1511 (s) cnr1.The following compounds were prepared in like manner to the procedure outlined in Example 5:(£)-l,2,3-Trichloro-5-(4-methoxystyryl )benzene (C44)Isolated as an off-white solid (3.7 g, 31%) : »H NM R (400 MHz, CDCb) δ 7.49 - 7.46 (m, 2H), 7.47 - 7.39 (m, 2H), 7.04 (d, J = 16.3 Hz, 1H), 6.93 - 6.89 ( m, 2H), 6.78 (d, J = 16.3 Hz, 1 H), 3.84 (s, 3H) ;13C NM R ( 101 MHz, CDCb) δ 159.46, 135.08, 134.23, 130.91, 129.85, 129. 16, 125.42, 114.02, 64.67, 55.32, 39.62, 38.48; EIMS m / z 313 ( [M ]+).(£)-l,2-Dlchloro-4-(4-methoxystyryl )benzene (C45)Isolated as an off-white solid (6.0 g, 53%) : mp 91 - 94CC; Ή NM R (400 MHz, CDCIs) δ 7.56 (d, J = 2.0 Hz, 1H), 7.46 - 7.42 (m, 2H), 7.39 (d, J = 8.4 Hz, 1H), 7.29 (dd, J = 8.4, 2.1 Hz, 1 H), 7.04 (d, J = 16.2 Hz, 1H), 6.93 - 6.88 (m, 2 H), 6.85 (d, J = 16.3 Hz, 1H), 3.84 (s, 3H) ;13C NM R ( 101 MHz, CDCIs) δ 159.75, 137.86, 132.72, 130.58, 130.49, 130.12, 129.33, 127.96, 127.77, 125.37, 123.98, 114.24, 55.35 ; EIMS m / z 279 ( [M]+).Example 6: Preparation of (f )-l-methoxy-4-(4-(trlfluoromethyl )styryl )benzene (C46)To a stirred solution of diethyl 4-methoxybenzyl phosphonate (8.89 g, 34.0 mmol) in Λ / , / V-dimethylformamide (30 mL) was added sodium methoxide powder ( 1.86 g, 34.0 mmol) . The reaction mixture was stirred at room temperature for 1 hour. The reaction mixture was cooled to 0 °C and 4-(trifluoromethyl)benzaldehyde (5.00 g, 28.0 mmol) in Λ / , / V-dimethylformamide (30 mL) was added dropwise. The reaction mixture was stirred at 60 °C for 2 hours. The reaction mixture was poured in ice cold water, filtered, and dried to afford the title compound as an off-white solid (3.60 g, 80%) : 'H NM R (300 MHz, CDCIs) δ 7.61 - 7.52 (m, 4H), 7.47 (d, J = 9.0 Hz, 2H ), 7.14 (d, J = 16.5 Hz, 1H), 6.97 (d, J = 16.5 Hz, 1H ), 6.91 (d, J = 9.0 Hz, 2H), 3.84 (s, 3H ) ; ESIMS m / z 279 ( [M + H]+).The following compounds were prepared in like manner to the procedure outlined in Example 6 :(£)-l-(4-Methoxystyryl )-3-(trifluoromethyl )benzene (C47)Isolated as an off-white solid (4.0 g, 85%) : Ή N MR (400 MHz, CDCb) δ 7.72 (s, 1H), 7.64 (d, J = 6.8 Hz, 1H), 7.50 - 7.44 (m, 4H), 7.12 (d, J = 16.0 Hz, 1H), 6.98 (d, J = 16.0 Hz, 1H), 6.91 (d, J = 8.8 Hz, 2H), 3.84 (s, 3H) ; ESIMS m / z 279 ( [M+ H ]+) .(£)-2-Chloro-4-(4-methoxystyryl )-l-(trifluoromethoxy)benzene (C48)F'"ΌIsolated: ESIMS m / z 329 ([M + H]+).(E)-l-(4-Methoxystyryl)-3,5-bis(trifluoromethyl)benzene (C49)F"CH 3F.F'Isolated as an off-white solid (4.0 g, 56%): Ή NMR (300 MHz, CDCh) δ 7.88 (s, 2H), 7.70 (s, 1H), 7.49 (d, J = 8.4 Hz, 2H), 7.19 (d, J = 16.5 Hz, 1H), 6.99 (d, J = 16.5 Hz, 1H), 6.92 (d, J = 8.4 Hz, 2H), 3.84 (m, 3H); ESIMS m / z 347 ([M + H]+).(f )-l,3-Dlbromo-5-(4-methoxystyryl)benzene (C50)Isolated as an off-white solid (2.2 g, 54%): Ή NMR (300 MHz, CDCh) δ 7.53 (s, 1H), 7.50 (s, 2H), 7.43 (d, J = 9.0 Hz, 2H), 7.05 (d, J = 16.2 Hz, 1H), 6.90 (d, J = 9.0 Hz, 2H), 6.79 (d, J = 16.2 Hz, 1H), 3.80 (s, 3H); ESIMS m / z 367 ([M + H]+).(£)-l-Chloro-3-(4-methoxystyryl)-5-(trifluoromethyl)benzene (C51)F VF-.F'Isolated as an off-white solid (4.3 g, 58%): Ή NMR (300MHz, CDCh) δ 7.62 (s, 1H), 7.58 (s, 1H), 7.48 - 7.42 (m, 3H), 7.12 (d, J = 16.2 Hz, 1H), 6.95 - 6.85(m, 3H), 3.84 (s, 3H); ESIMS m / z 313 ([M + H]+).(_r)-2-Bromo-l,3-dichloro-5-(4-methoxystyryl)benzene (C52)CIBrCIIsolated as an off-white solid (2.8 g, 40%): »H NMR (300 MHz, CDCb) δ 7.46 (s, 2H), 7.43 (d, J = 9.0 Hz, 2H), 7.07 (d, J = 13.5 Hz, 1H), 6.90 (d, J = 9.0 Hz, 1H), 6.73 (d, J = 13.5 Hz, 1H), 3.84 (s, 3H); ESIMS m / z 358 ([M + H]+).(E)-l-Bromo-3-chloro-5-(4-methoxystyryl)benzene (C53)CIIsolated as an off-white solid (4.0 g, 63%): Ή NMR (300 MHz, CDCb) δ 7.49 (s, 1H), 7.43 (d, J = 8.4 Hz, 2H), 7.38 (s, 1H), 7.35 (s, 1H), 7.05 (d, J = 16.5 Hz, 1H), 6.91 (d, J = 8.4 Hz, 2H), 6.80 (d, J = 16.5 Hz, 1H), 3.82 (s, 3H); ESIMS m / z 323 ([M + H]+). (E)-l-Chloro-3-fluoro-5-(4-methoxystyryl)benzene (C54)CIIsolated as an off-white solid (5.0 g, 60%): Ή NMR (400 MHz, CDCb) δ 7.45 (d, J = 8.4 Hz, 2H), 7.10 - 7.0 (m, 3H), 6.96 - 6.80 (m, 4H), 3.80 (s, 3H); ESIMS m / z 263 ([M + H]+).(E)-l-Chloro-2-fluoro-4-(4-methoxystyryl)benzene (C55)Isolated as an off-white solid (7.0 g, 84%): Ή NMR (400 MHz, CDCb) δ 7.44 (d, J = 8.0 Hz, 2H), 7.35 - 7.31 (m, 1H), 7.28 - 7.24 (m, 1H), 7.17 (dd, J = 1.6, 8.0 Hz, 1H), 7.03 (d, J = 16.0 Hz, 1H), 6.90 (d, J = 8.0 Hz, 1H), 7.49 (d, J = 8.0 Hz, 1H), 6.86 (d, J = 16.0 Hz, 1H), 3.82 (s, 3H); ESIMS m / z 263 ([M + H]+).(£)-2-Chloro-l-fluoro-4-(4-methoxystyryl)benzene (C56)FIsolated as an off-white solid (6.0 g, 72%): ESIMS m / z 263 ([M + H]+).(£)-l-Chloro-3-(4-methoxystyryl)-5-methyl benzene (C57)CH3Isolated as an off-white solid (5.0 g, 60%): Ή NMR (300 MHz, CDCb) δ 7.44 (d, J = 8.4 Hz, 2H), 7.28 (s, 1H), 7.15 (s, 1H), 7.05 - 7.00 (m, 2H), 6.91 - 6.83 (m, 3H), 3.83 (s, 3H), 2.24 (s, 3H); ESIMS m / z 259 ([M + H]+).(E)-l-Methoxy-4-(4-(perfluoroethyl)styryl)benzene (C58)F FIsolated as an off-white solid (0.5 g, 42%): Ή NMR (400 MHz, CDCb) δ 7.60 - 7.50 (m, 4H), 7.47 (d, J = 8.8 Hz, 2H),7.15 (d, J = 16.8 Hz, 1H), 6.98 (d, J = 16.8 Hz, 1H), 6.92 (d, J = 8.8 Hz, 2H), 3.82 (s, 3H); ESIMS m / z 329 ([M + H]+).(£)-l,2-bis(4-ethoxyphenyl)ethene (C59)Isolated as an off-white solid (1.7 g, 34%): Ή NMR (300 MHz, CDCb) δ 7.40 (d, J = 9.0 Hz, 4H), 6.91 (s, 2H), 6.87 (d, J = 9.0 Hz, 4H), 4.05 (q, J = 6.9 Hz, 4H), 1.42 (t, J = 6.9 Hz, 6H); ESIMS m / z 269 ([M + H]+).Example 7: Preparation of (E)-l,3-dichloro-2-fluoro-5-(4- methoxystyryl)benzene (C60)A stirred mixture of 5-bromo-l,3-dichloro-2-fluorobenzene (2.00 g, 8.20 mmol), l-methoxy-4-vinylbenzene (1.32 g, 9.80 mmol), and triethylamine (20 mL) under argon was degassed for 5 minutes. Palladium(II) acetate (0.0368 g, 0.164 mmol) and 1,1'- bis(diphenylphosphino)ferrocene (0.181 g, 0.328 mmol) were added and the reaction was heated to 90 °C for 16 hours. The reaction mixture was poured into water and extracted with ethyl acetate. The combined organic layers were dried over sodium sulfate, filtered, and concentrated. Purification by flash column chromatography provided the title compound as an off-white solid (1.60 g, 67%):lH NMR (300 MHz, CDCb) δ 7.41 (d, J = 8.8 Hz, 2H), 7.31 (s, 1H), 7.37 (s, 1H), 6.96 (d, J = 16.0 Hz, 1H), 6.89 (d, J = 8.8 Hz, 2H), 6.76 (d, J = 16.0 Hz, 1H), 3.84 (s, 3H); ESIMS m / z 297 ([M + H]+).The following compounds were prepared in like manner to the procedure outlined in Example 7:(£)-l,3-Dichloro-5-(4-methoxystyryl)-2-methylbenzene (C61)Isolated as an off-white solid (2.5 g, 67%): Ή NMR (300 MHz, CDCb) δ 7.43 (d, J = 8.7 Hz, 2H), 7.38 (s, 2H), 7.02 (d, J = 16.5 Hz, 1H), 6.90 (d, J = 8.7 Hz, 2H), 6.79 (d, J = 16.5 Hz, 1H), 3.82 (s, 3H), 2.42 (s, 3H); ESIMS m / z 293 ([M + H]+).(£)-l,2-Dichloro-5-(4-methoxystyryl)-3-methylbenzene (C62)Isolated as an off-white solid (3.0 g, 55%): »H NMR (300 MHz, CDCb) δ 7.50 - 7.40 (m, 3H), 7.24 (s, 1H), 7.02 (d, J = 15.9 Hz, 1H), 6.90 (d, J = 9.0 Hz, 2H), 6.81 (d, J = 15.9 Hz, 1H), 3.83 (s, 3H), 2.42 (s, 3H); ESIMS m / z 293 ([M + H]+).Example 8: Preparation of (E)-l,2,4-trichloro-5-(4-methoxystyryl)benzene (C63)0CH3CICICITo a sealed tube were added l -bromo-2,4,5-trichlorobenzene (3.0 g, 12 mmol), 1,2-dimethoxyethane: water ( 10 : 1 , 30 mL), (f)-2-(4-methoxystyryl)-4,4,5,5- tetramethyl- l,3,2-dioxaborolane (C64) (3.7 g, 14 mmol ), and potassium carbonate (3.2 g, 24 mmol) . The reaction mixture was degassed for 10 minutes with argon, followed by addition of tetrakis(triphenylphosphine)palladium(0) (0.55 g, 0.48 mmol) . The reaction mixture was degassed for 10 minutes then heated at 90 °C for 16 hours. The reaction mixture was poured in to water and extracted with ethyl acetate. The combined organic layers were dried over sodium sulfate, filtered, and concentrated . Purification by flash column chromatography provided the title compound as an off-white solid (3.0 g, 80%) : Ή NM R (400 MHz, CDC ) δ 7.73 (s, 1H), 7.50 - 7.45 (m, 3H), 7.20 (d, J = 16.0 Hz, 1 H), 7.02 (d, J = 16 Hz, 1H), 6.92 (d, J = 8.0 Hz, 2H), 3.84 (m, 3H) ; ESIMS m / z 313 ( [Μ + ΗΓ).Example 9: Preparation of (£)-2-(4-methoxystyryl )-4,4,5,5-tetramethyl-l,3,2- dloxaborolane (C64)To a 50 mL round-bottomed flask were added l-ethynyl-4-methoxybenzene (4.0 g, 30 mmol), 4,4,5,5-tetramethyl-l ,3,2-dioxaborolane (3.3 g, 36 mmol), zirconocene hydrochloride ( 1.2 g, 4.0 mmol), and triethylamine (2.8 mL, 15 mmol) at 0 °C. The reaction mixture was then stirred at 65 °C for 16 hours. The reaction mixture was poured in water and extracted with ethyl acetate. The combined organic layers were dried over sodium sulfate, filtered, and concentrated . Purification by flash column chromatography provided the title compound as an off-white semi solid (3.0 g, 38%) : Ή NM R (400 MHz, CDC ) δ 7.43 (d, J = 8.8 Hz, 2 H), 7.35 (d, J = 18.0 Hz, 1H), 6.86 (d, J = 8.8 Hz, 2H), 6.01 (d, J = 18.0 Hz, 1H ), 3.81 (s, 3H), 1.30 (s, 12H).Example 10: Preparation of 3,4,5-trichlorobenzaldehyde (C65)CIIn an oven dried, nitrogen flushed, 500 mL round-bottomed flask equipped with a pressure equalizing addition funnel, 5-bromo- l,2,3-trichlorobenzene ( 10.0 g, 38.4 mmol) was dissolved in tetrahydrofuran ( 100 mL), and the resulting solution was cooled in an ice bath under nitrogen. / soPropyl magnesium chloride (2 M solutiontetrahydrofuran, 21. 1 mL, 42.3 mmol) was added dropwise with good stirring over 15 minutes via the addition funnel . After 0.5 hours, Λ / , / V-dimethylformamide (3.72 mL, 48.0 mmol) was added to the dark solution with stirring . After an additional 0.5 hours, hydrochloric acid ( 1 N, 100 mL) was added with stirring . The layers were separated, and the organic layer was washed with brine. The combined aqueous layers were extracted with ether, and the combined organics were dried over sodium sulfate, filtered, and concentrated to afford the title compound as a white solid ( 10 : 1 mixture of title compound to 1,2,3-trichlorobenzene, 7.96 g, 99%) : Ή NM R (CDCb) δ 9.91 (s, 1H), 7.88 (s, 2H) ; EIMS m / z 209 ( [M ]+).Example 11: Preparation of l-bromo-4-(perfluoroethyl )benzene (C66)F FTo a stirred solution of l-(4-bromophenyl)-2,2,2-trifluoroethanone ( 5.00 g, 19.7 mmol) in dichloromethane under argon were added 4-tert-butyl-2,6- dimethylphenylsulfur trifluoride (2.90 g, 11.8 mmol) and hydrogen fluoride pyridine complex (0.190 g, 9.80 mmol) at 0 °C. The reaction mixture was allowed to warm to room temperature and stirred for 16 hours. The reaction mixture was poured into water and extracted with ethyl acetate. The combined organic extracts were dried over sodium sulfate, filtered, and concentrated. Purification by flash column chromatograph provided the title compound as colorless liquid ( 1.00 g, 20%) :lH N M R (300 MHz, CDCb) δ 7.65 (d, J = 9.0 Hz, 2H ), 7.47 (d, J = 9.0 Hz, 2H) ; EIMS m / z 274 ( [M ]+).Example 12: Preparation of trans-2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropanecarboxamido)benzoic acid (C67)CITo a solution of trans-2, 2-dichloro-3-(3, 5-dichlorophenyl)cyclopropanecarboxylic acid (CI ) (0.300 g, 1.00 mmol) in dichloromethane ( 5.00 mL) stirred at 0 °C, were added Λ / , V-dimethylformamide ( 1 drop) followed by oxalyl chloride (0.131 mL, 1.50 mmol) over 2 minutes. The ice batch was removed and the reaction allowed to warm toroom temperature over 90 minutes. The reaction was then concentrated to yield a yellow-orange semi-solid. The semi-solid was dissolved in dichloromethane (3.5 ml_), and the solution was added slowly to a cooled solution of 5-amino-2-chlorobenzoic acid (0.206 g, 1.20 mmol) and triethylamine (0.209 ml_, 1.50 mmol) in dichloromethane (7 mL) . The ice bath was removed and the reaction was allowed to wa rm to room temperature over 90 minutes. The reaction was diluted with dichloromethane ( 10 mL) and washed with hydrochloric acid (0.1 N ). The resulting slurry was filtered and the solid washed with water. The precipitated solid was dried in a vacuum oven at 40 °C to provide the title compound as a light brown solid (0.421 g, 93%) : mp 234 - 236 °C; Ή NM R (400 MHz, DMSO-cfc) δ 13.47 (s, 1H), 10.90 (s, 1 H), 8.16 (d, J = 2.3 Hz, 1H ), 7.78 (dd, J = 8.7, 2.4 Hz, 1H), 7.59 (m, 4H), 3.56 (dd, J = 49.8, 8.5 Hz, 2H), 1.09 ( m, 1H);13C NMR ( 101 MHz, DMSO-de) δ 166.26, 165.77, 162.61, 137.57, 137.27, 134.04, 132.18, 131.44, 131.22 , 127.88, 127.66, 126.40, 125.92, 122.88, 121. 17, 102.37, 62.11, 38.41, 36.83; ESIMS m / z 454 ( [M + H]+).Example 13: Preparation of trans-2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)- V-(4-fluorophenyl )benzamide (Fl )CI5-Amino-2-chloro- / V-(4-fluorophenyl)benzamide (C69) (0.174 g, 0.656 mmol) and 4-dimethylaminopyridine (0.087 g, 0.711 mmol) were sequentially added to a stirred mixture of trans-2, 2-dichloro-3-(3, 5-dichlorophenyl)cyclopropanecarboxylic acid (CI ) (0.164 g, 0.547 mmol) and l-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (0. 157 g, 0.820 mmol) in 1,2-dichloroethane (5.5 mL) at roomtemperature. The reaction was stirred at room temperature for 20 hours. The reaction was diluted with dichloromethane, washed with saturated aqueous sodium bicarbonate (2x), and washed with hydrochloric acid ( 1 N) (2x). The organic phase was dried over magnesium sulfate, filtered, and concentrated . Purification by flash columnchromatography using 0- 100% ethyl acetate / hexanes as eluent provided the title compound as a white foam (0.138 g, 46%) .The following compounds were prepared in like manner to the procedure outlined in Example 13 :trans-3-{ 2, 2-Dichloro-3-(3,5-dichlorophenyl )cyclopropane-l-carboxamido)- / V- (4-fluorophenyl )benzamide (F 2)CIIsolated as a brown solid (0.106 g, 79%).trans-5-{ 2, 2-Dichloro-3-(3,5-dichlorophenyl)cyclopropane-l-carboxamido)-V- (4-fluorophenyl)-2-(trif1uoromethyl)benzamide (F3)FCIIsolated as a yellow solid (0.074 g, 34%).trans-5-( 2, 2-Dichloro-3-(3,5-dichlorophenyl)cyclopropane-l-carboxamido)- / V- (4-fluorophenyl)-2-iodobenzamide (F4)CIIsolated as a brown solid (0.078 g, 50%).trans-2-Chloro-v-(4-cyanophenyl)-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)benzamide (F5)Isolated as a yellow solid (0.081 g, 39%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-A / -(4-(trifluoromethyl)phenyl)benzamide (F6)CICIFFCIIsolated as a yellow solid (0.082 g, 49%) .trans-2-Chloro- / V-(4-chlorophenyl )-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F7)CIIsolated as a yellow solid (0.083 g, 47%) .trans-2-Chloro- / V-(2-chloro-4-fluorophenyl )-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F8)CICIFCIIsolated as a yellow solid (0.075 g, 42%) .trans-2-Chloro-5-( 2,2-dlchloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(o-tolyl )benzamide (F9)CIIsolated as a brown solid (0.104 g, 54%) .trans-5-{ 2, 2-Dichloro-3-(3,5-dichlorophenyl )cyclopropane-l-carboxamido)- V- (4-fluorophenyl )-2-methylbenzamide (FIO)CH3CIFCIIsolated as a white solid (0.095 g, 50%).trans-2-Bromo-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl)benzamlde (Fll)Isolated as a red solid (0.085 g, 51%).trans-5-{ 2, 2-Dichloro-3-(3,5-dichlorophenyl)cyclopropane-l-carboxamido)-V- (4-fluorophenyl)-2-(lH-l,2,4-triazol-l-yl)benzamide (F12)CIFCIIsolated as a brown solid (0.103 g, 60%).trans-2-Chloro-5-(2,2-dichloro-3-(3,4,5-trichlorophenyl)cyclopropane-l- carboxamido)-A / -(4-fluorophenyl)benzamide (F13)Isolated as a white powder (0.090 g, 79%).trans-2-Chloro-5-(2,2-dichloro-3-(3,4-dichlorophenyl)cyclopropane-l- carboxamido)-A / -(4-fIuorophenyl)benzamide (F14)CICIFCIIsolated as an off-white powder (0.155 g, 77%).trans-3-( 2, 2-Dichloro-3-(3,5-dichlorophenyl)cyclopropane-l-carboxamido)-2- fIuoro-v-(4-f1uorophenyl)benzamide (F15)CIFCIIsolated as a yellow oil (0.025 g, 18%).trans-2-Chloro-5-(2,2-Dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-phenylbenzamide (F16)CIIsolated as a white solid (0.092 g, 66%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(2-fluorophenyl)benzamide (F17)CICICIIsolated as a white solid (0.030 g, 21%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamldo)- / V-(2,4-difluorophenyl)benzamide (F18)CICIFCIIsolated as a white solid (0.108 g, 72%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )-A / -methylbenzamide (F 19)CIIsolated as a white solid (0.137 g, 92%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(3-f1uorophenyl )benzamlde (F20)CIIsolated as a pink solid (0.115 g, 79%) .trans-2-Chloro- / V-(3-cyanophenyl )-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F21 )CI CI n ^ '°CICIIsolated as a white solid (0.113 g, 76%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(2,3-difluorophenyl )benzamide (F22)CIIsolated as a white solid (0.121 g, 80%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(2,4,6-trlf1uorophenyl )benzamide ( F24)CIIsolated as a light pink solid (0.092 g, 61%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(pyridin-4-yl )benzamide (F26)CI CI CIoCI NHCIIsolated as a white solid (0.112 g, 64%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(pyridin-3-yl )benzamide (F27)CIIsolated as a white solid (0.138 g, 78%).trans-5-{ 2, 2-Dichloro-3-(3,4-dichlorophenyl )cyclopropane-l-carboxamido)-2- fluoro-A / -(4-fluorophenyl )benzamide (F28)Isolated as a white solid (0.130 g, 92%) .trans-5-( 2, 2-Dichloro-3-(3,4,5-trichlorophenyl )cyclopropane-l-carboxamido)- 2-f1uoro- / V-(4-fluorophenyl )benzamide ( F 29)CI CIn^crYCIIsolated as a white solid (0.121 g, 90%) .trans-3-( 2, 2-Dichloro-3-(3,5-dichlorophenyl )cyclopropane-l-carboxamido)- / V- (4-fluorophenyl )-2-methoxybenzamlde (F30)CIIsolated as a yellow solid (0.069 g, 47%) .trans-2-Chloro- / V-(2-chloropyridin-3-yl )-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F31 )CIIsolated as a white solid (0.126 g, 67%).trans-2-Chloro- / V-(6-chloropyridin-3-yl )-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F32)Isolated as a white solid (0.131 g, 70%).trans-2-Chloro- / V-(6-cyanopyridin-3-yl )-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F33)Isolated as a white solid (0.094 g, 51%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(3-f1uorophenyl )-A / -methylbenzamide (F34)CI CIIsolated as a white solid (0.119 g, 80%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(2-f1uorophenyl )-A / -methylbenzamide (F35)CIIsolated as a white solid (0.123 g, 82%).trans-2-Chloro- / V-(4-cyano-2-methylphenyl )-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F36)Isolated as a white solid (0.103 g, 68%).trans-2-Chloro-5-( 2,2-dlchloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uoro-2-methyl phenyl )benzamide (F37)XIIsolated as a white solid (0.112 g, 75%).trans-2-Chloro- / V-(2-chlorophenyl )-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F38)CIIsolated as a white foam (0.101 g, 77%).trans-2-Chloro-5-(2,2-dichloro-3-(3,4-dichlorophenyl)cyclopropane-l- carboxamldo)-W-(2,4-difluorophenyl)benzamide (F39)Isolated as a white foam (0.096 g, 68%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f4,5-trichlorophenyl)cyclopropane-l- carboxamido)- / V-(2,4-difluorophenyl)benzamide (F40)Isolated as a white solid (0.104 g, 77%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropan carboxamido)- / V-(2-isopropyl phenyl )benzamide (F41)CIIsolated as a white solid (0.104 g, 78%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropan carboxamido)- / V-(2-ethyl-6-methylphenyl)benzamide (F42)CI CH 3CICIIsolated as a white solid (0.103 g, 77%).trans-2-Chloro- / V-(3-chlorophenyl )-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F43)CIIsolated as a white solid (0.029 g, 22%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(2,4-difluorophenyl )-A -methylbenzamide (F44)CICIFCIIsolated as a white foam (0.082 g, 57%).trans-5-{ 2, 2-Dichloro-3-( 3,5-dichlorophenyl )cyclopropane-l-carboxamido)-2- fluoro-A / -(4-f1uorophenyl )-W-methylbenzamlde (F45)CIIsolated as a white solid (0.077 g, 57%).trans-5-{ 2, 2-Dichloro-3-( 3,5-dichlorophenyl )cyclopropane-l-carboxamido)-2- fluoro-A / -(3-f1uorophenyl )-W-methylbenzamlde (F46)CIIsolated as a white solid (0.096 g, 70%).trans-3-{ 2, 2-Dichloro-3-(3,5-dichlorophenyl )cyclopropane-l-carboxamido)-2- fluoro-A / -(4-f1uorophenyl )-W-methylbenzamlde (F47)CIIsolated as a yellow glass (0.106 g, 78%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-4-f1uoro-A -(4-fluorophenyl )benzamide (F48)CIIsolated as a yellow foam (0.083 g, 59%).trans-5-{ 2, 2-Dichloro-3-(3,5-dichlorophenyl )cyclopropane-l-carboxamido)- 2,4-dif1uoro-A -(4-fluorophenyl )benzamlde (F49)CIIsolated as a white solid (0.061 g, 45%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,4,5-trichlorophenyl )cyclopropane-l- carboxamido)- v-(3-fluorophenyl )benzamide (F50)Isolated as a white solid (0.104 g, 76%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f4,5-trichlorophenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)-A / -methylbenzamide (F52)CIIsolated as a white solid (0.113 g, 85%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f4-dichlorophenyl)cyclopropan carboxamido)- / V-(4-fluorophenyl)-A / -methylbenzamide (F53)CICIIsolated as a white solid (0.094 g, 67%).trans-2-Chloro-V-(4-cyano-2-methylphenyl)-5-(2,2-dichloro-3-(3,4,5- trichlorophenyl)cyclopropane-l-carboxamido)benzamide (F54)Isolated as a white solid (0.085 g, 63%).trans-2-Chloro- / V-(4-cyano-2-methylphenyl)-5-(2,2-dichloro-3-(3,4- dichlorophenyl)cyclopropane-l-carboxamido)benzamlde (F55)XIcr ^ "°Isolated as a white solid (0.088 g, 62%).trans-2-Chloro-5-(2,2-dlchloro-3-(3-(trif1uoromethyl)phenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)benzamide (F56)XI^'x OFIsolated as a white solid (0.120 g, 78%).trans-2-Chloro-5-(2,2-dichloro-3-(3-(trif1uoromethyl)phenyl)cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl)-A / -methylbenzamide (F57)Isolated as a white solid (0.102 g, 61%).trans-2-Chloro-5-(2,2-dichloro-3-(3-(trlf1uoromethyl)phenyl)cyclopropane-l- carboxamido)-v-(2,6-difluorophenyl)benzamide (F58)0Isolated as a white solid (0.066 g, 42%).trans-5-( 2, 2-Dichloro-3-(3,4-dichlorophenyl )cyclopropane-l-carboxamido)-2- fluoro-A -(4-fluorophenyl )- / V-methyl benzamlde (F59)CIIsolated as a white solid (0.117 g, 86%).trans-5-( 2, 2-dichloro-3-( 3, 4,5-trichlorophenyl )cyclopropane-l-carboxamido)- 2-f1uoro-A -(4-fluorophenyl )-A / -methylbenzamide (F60)cryciIsolated as a white solid (0.027 g, 21%).trans-5-( 2, 2-Dichloro-3-( 3,5-dichlorophenyl )cyclopropane-l-carboxamido)-A - (2,4-dif1uorophenyl )-2-fluorobenzamide (F61)CIIsolated as a white solid (0.120 g, 73%) .trans-5-i 2, 2-Dichloro-3-( 3,4-dichlorophenyl )cyclopropane-l-carboxamido)-A - (2,4-dif1uorophenyl )-2-fluorobenzamide (F62)Isolated as a white solid (0.102 g, 62%).frans-5-(2,2-Dichloro-3-(3,5-dlchlorophenyl )cyclopropane-l-carboxamido)-N- (2,4-dlf1uorophenyl )-2-fluoro-A -methylbenzamide (F63)CI CIIsolated as a white solid (0.123 g, 73%).trans-5-{ 2, 2-Dichloro-3-( 3,4-dichlorophenyl )cyclopropane-l-carboxamido)- V- (2,4-difluorophenyl )-2-fluoro-A / -methylbenzamide (F64). FIsolated as a white foam (0.110 g, 65%).trans-5-( 2, 2-Dichloro-3-(3,4,5-trichlorophenyl )cyclopropane-l-carboxamido)- A -( 2,4-dif1uorophenyl )-2-fIuoro-W-methylbenzamide (F65)- FIsolated as a white solid (0.098 g, 55%) .trans-5-{ 2, 2-Dichloro-3-(3,5-dichlorophenyl )cyclopropane-l-carboxamido)-2- fluoro-A -methyl- v-phenylbenzamide (F66)CI CIIsolated as a white foam (0.123 g, 78%).trans-5-{ 2, 2-Dichloro-3-( 3,4-dichlorophenyl )cyclopropane-l-carboxamido)-2- fluoro-A / -methyl- / V-phenylbenzamide (F67)Isolated as a white foam (0.124 g, 79%).trans-5-( 2, 2-Dichloro-3-(3,4,5-trichlorophenyl )cyclopropane-l-carboxamido)- 2-fluoro- / V-methyl- / V-phenylbenzamide (F68)CIIsolated as a white solid (0.122 g, 72%) .trans-3-( 2, 2-Dichloro-3-(3,5-dichlorophenyl )cyclopropane-l-carboxamido)-2- fIuoro- v-methyl- / V-phenylbenzamide ( F69)CI CIIsolated as a yellow foam (0.101 g, 64%).frans-3-(2,2-Dichloro-3-(3,4-dlchlorophenyl )cyclopropane-l-carboxamido)-2- f1uoro-A / -methyl-A -phenylbenzamlde (F70)Isolated as a light yellow foam (0.107 g, 68%) .trans-3-( 2, 2-Dichloro-3-( 3,4, 5-trichlorophenyl )cyclopropane-l-carboxamido)- 2-fluoro-A / -methyl-A -phenylbenzamide ( F71 )CI CIIsolated as a light yellow foam (0.114 g, 68%).trans-5-(3-(4-Bromo-3,5-dichlorophenyl)-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro-A-(4-f1uorophenyl)benzamide (F72)Isolated as a white solid (0.030 g, 22%).trans-2-Chloro-5-(2,2-dlchloro-3-(2f4,5-trichlorophenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)benzamide (F73)CIcr ^ iIsolated as a white solid (0.047 g, 32%).trans-2-Chloro-5-(2,2-dichloro-3-(2,4,5-trichlorophenyl)cyclopropane-l- carboxamido)-A-(4-fluorophenyl)-A / -methylbenzamide (F74)Isolated as a white solid (0.109 g, 73%).frans-5-(2,2-Dichloro-3-(3,4,5-trichlorophenyl)cyclopropane-l-carboxamido)- N-(2,4-difluorophenyl)-2-f1uorobenzamide (F75)Isolated as a white solid (0.098 g, 56%).frans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(5-fluoropyridin-2-yl)benzamide (F76)CI CIIsolated as a white solid (0.029 g, 23%).trans-5-(2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)benzamido)-A-methylpicolinamide (F77)Isolated as a white solid (0.039 g, 25%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)-W-(pyridin-2-yl)benzamide (F78)Isolated as a white solid (0.071 g, 51%).trans-2-Chloro-5-(2,2-dlchloro-3-(3-chloro-4- (trifluoromethoxy)phenyl)cyclopropane-l-carboxamldo)- / V-(4- fluorophenyl)benzamide (F79)CI CIF'^O'Isolated as a white solid (0.082 g, 57%).trans-2-Chloro-5-(2,2-dichloro-3-(3-chloro-4-(trifIuoromethoxy)phenyl)cyclopropane-l-carboxamido)- / V-(4-fluorophenyl)-v- methylbenzamide (F80)Isolated as a white solid (0.111 g, 75%).trans-2-Chloro-5-(2,2-dlchloro-3-(4-(trif1uoromethyl)phenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)benzamide (F81)Isolated as a white solid (0.123 g, 80%).trans-2-Chloro-5-(2,2-dlchloro-3-(4-(trif1uoromethyl)phenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)-A / -methylbenzamide (F82)Isolated as a white solid (0.130 g, 82%).trans-2-Chloro-5-(2,2-dlchloro-3-(4-(trif1uoromethyl)phenyl)cyclopropane-l- carboxamido)- / V-(2,6-difluorophenyl)benzamide (F83)Isolated as a white solid (0.082 g, 52%).trans-5-(3-(3,5-Bis(trifluoromethyl)phenyl)-2,2-dlchlorocyclopropane-l- carboxamldo)-2-chloro-A-(4-fluorophenyl)benzamlde (F84)CI CIIsolated as a white solid (0.042 g, 30%).trans-5-(3-(3,5-Bis(trifluoromethyl)phenyl)-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro-A / -(4-fluorophenyl)-A / -methylbenzamide (F85)Isolated as a white solid (0.092 g, 64%).frans-5-(3-(3,5-Bis(trifluoromethyl)phenyl)-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro-N-(2,6-dif1uorophenyl)benzamide (F86)Isolated as a white solid (0.038 g, 26%).trans-2-Chloro-5-(2,2-dichloro-3-(3-chloro-5- (trifluoromethyl)phenyl)cyclopropane-l-carboxamido)-A-(4- f1uorophenyl)benzamlde (F87)Isolated as a white solid (0.055 g, 38%).trans-2-Chloro-5-(2,2-dlchloro-3-(3-chloro-5-(trifJuoromethyl)phenyl)cvclopropane-l-carboxamldo)-v-(4-fluorophenyl)- / V- methylbenzamide (F88)CIIsolated as a white solid (0.095 g, 63%).trans-2-Chloro-5-(2,2-dlchloro-3-(3-chloro-5- (trifluoromethyl)phenyl)cyclopropane-l-carboxamido)- / V-(2,6- dif1uorophenyl)benzamide (F89)BrIsolated as a white solid (0.023 g, 16%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dibromophenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)-v-methylbenzamide (F91)BrIsolated as a white solid (0.066 g, 47%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dibromophenyl)cyclopropane-l- carboxamldo)- / V-(2,6-difluorophenyl)benzamide (F92)BrIsolated as a white solid (0.020 g, 14%).trans-v-(4-Cyano-2-f1uorophenyl)-5-(2,2-dlchloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)-2-fluorobenzamlde (F93)CIIsolated as a white solid (0.108 g, 78%).trans-N -(4-Cyano-2-f1uorophenyl)-5-(2,2-dichloro-3-(3,4- dichlorophenyl)cyclopropane-l-carboxamido)-2-fluorobenzamlde (F94)Isolated as a white solid (0.013 g, 10%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichloro-4-f1uorophenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)benzamide (F96)CICIFFCIIsolated as a white solid (0.017 g, 11%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichloro-4-fluorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )-A / -methylbenzamide (F97)Isolated as a white solid (0.063 g, 41%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichloro-4-fluorophenyl )cyclopropane-l- carboxamldo)-W-(2,6-difluorophenyl )benzamide (F98)CIIsolated as a white solid (0.025 g, 16%).trans-2-Chloro-5-( 2,2-dlchloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-ethyl-A -(4-f1uorophenyl )benzamide (F99)CIIsolated as a white solid (0.087 g, 60%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )-A / -( 2,2,2-trif1uoroethyl )benzamlde (FIOO)FCIFCIIsolated as a white solid (0.095 g, 60%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamido)- v-(4-fluorophenyl )- / V-propylbenzamide (F101)CH3CIFCIIsolated as a yellow foam (0.090 g, 61%).frans-A -Allyl-2-chloro-5-(2,2-dichloro-3-(3,5-dlchlorophenyl )cyclopropane-l- carboxamido)-A / -(4-fluorophenyl )benzamide (F102)CH2CIIsolated as an orange foam (0.047 g, 32%) .trans-2-chloro-A -(4-cyano-2-f1uorophenyl )-5-(2,2-dichloro-3-(3,4- dichlorophenyl )cyclopropane-l-carboxamido)benzamide (F 103)Isolated as a colorless oil (0.032 g, 22%) .frans-2-Chloro-yv-(4-cyano-2-f1uorophenyl )-5-(2,2-dichloro-3-(3,4,5- trichlorophenyl )cyclopropane-l-carboxamldo)benzamide (F104)Isolated as a white foam (0.016 g, 11%).trans-v-(4-Cyano-2-fluorophenyl)-5-(2,2-dichloro-3-(3,4,5- trlchlorophenyl)cyclopropane-l-carboxamido)-2-fluoro-A / -methylbenzamlde (F105)CI CIIsolated as a white foam (0.020 g, 20%).trans-2-Chloro- / V-(4-cyano-2-fluorophenyl)-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)-A-methylbenzamide (F106)XICIIsolated as a colorless oil (0.041 g, 28%).trans-2-Chloro- / V-(4-cyano-2-fluorophenyl)-5-(2,2-dichloro-3-(3,4- dichlorophenyl)cyclopropane-l-carboxamido)-A-methylbenzamide (F107)XIIsolated as a white foam (0.034 g, 23%).trans-2-Chloro-V-(4-cyano-2-fJuorophenyl)-5-(2,2-dichloro-3-(3,4,5- trichlorophenyl)cyclopropane-l-carboxamido)-A / -methylbenzamide (F108)Isolated as a yellow film (0.011 g, 6%).trans-2-Chloro-5-(2,2-dichloro-3-phenylcvclopropane-l-carboxamldo)- / V-(4- fluorophenyl)- / V-methylbenzamide (F110)Isolated as a yellow film (0.011 g, 6%).trans-2, 2-Dichloro-iV-(4-chloro-3-( (4- fluorophenyl) (methyl )carbamothioyl)phenyl)-3-( 3,5- dichlorophenyl)cyclopropane-l-carboxamide (F112)CIIsolated as a yellow solid (0.024 g, 25%) .trans-2,2-Dichloro-A / -(4-chloro-3-((4-fluorophenyl )carbamothioyl )phenyl )-3- (3,5-dichlorophenyl )cyclopropane-l-carboxamlde (F 113)CIIsolated as a yellow solid (0.027 g, 13%) .trans- v-(4-Cyano-2-fluorophenyl )-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)-2-fluoro-A / -methylbenzamide (F114)CIIsolated as a colorless glass (0.004 g, 4%) .trans-5-{ 2, 2-Dichloro-3-( 3,5-dichlorophenyl )cyclopropane-l-carboxamido)- / V- (4-fluorophenyl )-2-( methyl thlo)benzamide (F115)CIIsolated as a white solid (0.173 g, 28%).trans-2-Chloro-5-( 2,2-dichloro-3-(3-chloro-5-methyl phenyl )cyclopropane- 1- carboxamido)-A / -(4-fluorophenyl )benzamide ( F116)Isolated as a white solid (0.083 g, 59%).trans-2-Chloro-5-( 2,2-dichloro-3-(3-chloro-5-methyl phenyl )cyclopropane- 1- carboxamldo)-W-(4-f1uorophenyl )-A / -methylbenzamide (F 117)CIIsolated as a white foam (0.100 g, 69%).trans-2-Chloro-5-( 2,2-dichloro-3-(3-chloro-5-methyl phenyl )cyclopropane- 1- carboxamldo)-W-(2,6-difluorophenyl )benzamide (F 118)H,CIsolated as a white foam (0.066 g, 45%).trans-2-Chloro-5-( 2,2-dlchloro-3-(3,5-dichloro-4-methyl phenyl )cyclopropane- l-carboxamido)-A / -(4-fluorophenyl )benzamide (F119)H,CIsolated as a white foam (0.028 g, 21%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichloro-4-methyl phenyl )cyclopropane- l-carboxamido)-A / -(4-fluorophenyl )-A / -methylbenzamide (F120)Isolated as a white solid (0.077 g, 56%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichloro-4-methyl phenyl )cyclopropane- l-carboxamido)-A / -( 2,6-dlf1uorophenyl )benzamide (F 121 )CIIsolated as a white foam (0.025 g, 18%).trans-2-Chloro-5-( 2,2-dibromo-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )benzamlde (F122)Isolated as an off-white solid (0.075 g, 45%) .trans-2-Chloro-5-( 2,2-dlchloro-3-(3,4-dichloro-5-methyl phenyl )cyclopropane- l-carboxamido)-A / -(4-fluorophenyl )benzamide (F123)XIIsolated as a white foam (0.102 g, 76%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,4-dichloro-5-methyl phenyl )cyclopropane- l-carboxamido)-A / -(4-fluorophenyl )-A / -methylbenzamide (F124)Isolated as a white foam (0.094 g, 68%).Example 14: Preparation of trans-4-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)-A -(4-fluorophenyl )picolinamlde (F126)CITo a solution of trans-2, 2-dichloro-3-(3,5-dichlorophenyl)cyclopropanecarboxylic acid (CI ) (0. 100 g, 0.333 mmol) in dichloromethane (3.33 mL) at 0 °C was added N,N- dimethylformamide ( 1 drop) and oxalyl chloride (0.0440 mL, 0.500 mmol) dropwise. The cold bath was removed and the reaction was stirred at room temperature for 1 hour. The reaction was again cooled to 0 °C, and W-methylmorpholine (0.110 mL, 1.000 mmol) followed by 4-amino-W-(4-fluorophenyl)picolinamide (C81 ) (0.154 g, 0.667 mmol ) were added. The reaction was stirred at room temperature for 1 hour. The reaction was diluted with dichloromethane, washed with saturated aqueous sodium bicarbonate (2x), and washed with hydrochloric acid ( 1 N ) (2x) . The organic phase was dried over magnesium sulfate, filtered, and concentrated . Purification by flash columnchromatography using 0-100% ethyl acetate / hexanes as eluent provided the title compound as a glassy clear solid (0.0800 g, 44%).The following compounds were prepared in like manner to the procedure outlined in Example 14 :trans-2-Chloro-3-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamldo)- / V-(4-f1uorophenyl)benzamlde (F127)CIFCIIsolated as a white solid (0.102 g, 67%).trans-5-( 2, 2-Dichloro-3-(3,5-dichlorophenyl)cyclopropane-l-carboxamido)- / V- (4-fluorophenyl)-2-methoxybenzamlde (F128)CH3OCIFCIIsolated as a white solid (0.040 g, 26%).trans-5-{ 2, 2-Dichloro-3-(3,5-dichlorophenyl)cyclopropane-l-carboxamido)-2- fluoro- / V-(4-fluorophenyl)benzamide (F129)FCIFCIIsolated as a white solid (0.081 g, 58%).trans-4-Chloro-3-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-v-(4-fluorophenyl)benzamide (F130)CIIsolated as an off-white solid (0.099 g, 65%).trans-3-Chloro-6-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-v-(4-fluorophenyl)picolinamide (F131)CI CIIsolated as a faint yellow solid (0.116 g, 75%) .trans-2-Cyano-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )benzamlde (F132)Isolated as a yellow film (0.043 g, 38%).frans-6-(2,2-Dichloro-3-(3,5-dlchlorophenyl )cyclopropane-l-carboxamido)- / V- (4-fluorophenyl )plcolinamide (F133)Isolated as a clear glassy solid (0.033 g, 40%) .frans-3-(2,2-Dichloro-3-(3,5-dlchlorophenyl )cyclopropane-l-carboxamido)- / V- (4-fluorophenyl )-4-methylbenzamide (F134)Isolated as an off-white solid (0.039 g, 35%) .frans-5-(2,2-Dichloro-3-(3,5-dlchlorophenyl )cyclopropane-l-carboxamido)- / V- (4-fluorophenyl )-2-(trlf1uoromethoxy)benzamide ( F135)FCIIsolated as a white solid (0.108 g, 65%).trans-3-Chloro-5-( 2,2-dlchloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-fluorophenyl )benzamlde (F136)CIIsolated as a clear glassy solid (0.078 g, 51%) .Example 15: Preparation of trans-2-chloro-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)- / V-(4-nitrophenyl )benzamide (F137)To a solution of 4-nitroaniline (0.0270 g, 0.198 mmol) in dichloromethane (2 ml_) was added in sequence l-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (0.0480 g, 0.248 mmol), 4-dimethylaminopyridine (0.0240 g, 0.198 mmol), and trans- 2-chloro-5-(2,2-dichloro-3-(3, 5-dichlorophenyl)cyclopropanecarboxamido)benzoic acid (C67) (0.0750 g, 0. 165 mmol). The reaction was stirred at room temperature for 16 hours. The reaction was loaded onto Celite -', and purification by flash column chromatography using 0-25% ethyl acetate / hexanes as eluent provided the title compound as a yellow solid (0.0131 g, 14%).The following compounds were prepared in like manner to the procedure outlined in Example 15:irans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)- / V-( l,2,3-thiadiazol-5-yl )benzamide ( F 138)CIIsolated as a white solid (0.024 g, 27%) .Example 16: Preparation of trans-3-( 2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamldo)pyridine 1-oxide (F139)CITo a solution of trans-2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)- / V-(pyridin-3-yl)benzamide ( F27) (0.0930 g, 0.176 mmol) in dichloromethane (4 ml.) was added meta-chloroperoxybenzoic acid (0.0404 g, 0. 176 mmol) . The reaction was stirred at room temperature for 14 hours. Celite" was added to the reaction and the solvent was concentrated . Purification by flash column chromatography using 0- 10% methanol / dichloromethane as eluent provided the title compound as a white solid (0.0813 g, 85%) .The following compounds were prepared in like manner to the procedure outlined in Example 16 :trans-4-( 2-Chloro-5-( 2, 2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamido)benzamido)pyridine 1-oxide (F 140)CIIsolated as a white solid (0.035 g, 34%).trans-4-( 2, 2-Dichloro-3-( 3,5-dichlorophenyl )cyclopropane-l-carboxamido)-2- ((4-fluorophenyl )carbamoyl )pyridine 1-oxide ( F141 )ΘCIFCIIsolated as a faint yellow solid (0.038 g, 58%) .Example 17: Preparation of trans-2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)- V-(6-fluoropvridin-3- yl )benzamide (F142)CI6-Fluoropyridin-3-amine (0.0290 g, 0.254 mmol) was dissolved indichloromethane (2 ml_) . The solution was cooled in an ice bath. Triethylamine (0.0440 mL, 0.318 mmol) was added . trans-2-Chloro-5-(2,2-dichloro-3-(3, 5- dichlorophenyl)cyclopropane-l-carboxamido)benzoyl chloride (C68) (0.100 g, 0.212 mmol) was dissolved in dichloromethane (2 mL), and the solution was added to the reaction mixture. The ice bath was removed and the reaction allowed to stir overnight at room temperature. The reaction was loaded onto Ceiite5and purified by flash column chromatography using 0-40% ethyl acetate / hexanes as eluent to afford the title compound as a white solid (0.0339 g, 29%) .The following compounds were prepared in like manner to the procedure outlined in Example 17:trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-(methylsulfonyl )phenyl )benzamide (F143)CICIo / / / "CH3CIIsolated as a white solid (0.040 g, 30%).trans-2-Chloro- / V-(4-cyano-2-fluorophenyl )-5-(2,2-dichloro-3-( 3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F 144)Isolated as a white solid (0.028 g, 23%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(oxazol-2-yl )benzamide (F145)CIIsolated as a light brown solid (0.021 g, 19%) .Example 18: Preparation of frans-2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)-A -(4-methoxyphenyl )benzamide (F146)CITo a solution of trans-2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropanecarboxamido)benzoic acid (C67) (0. 100 g, 0.212 mmol) in dichloromethane (0.1 mL) was added / V, / V-dimethylformamide (one drop), and the reaction cooled in an ice bath. Oxalyl chloride (0.0438 mL, 0.254 mmol) was charged slowly over about 5 minutes. The reaction was removed the ice bath and allowed to warm to room temperature over 90 minutes. The reaction was then concentrated. The residue was re-dissolved in dichloromethane (0.1 mL). This solution was added to a cooled (ice bath) separate solution of 4-methoxyaniline (0.0310 g, 0.254 mmol) and triethylamine (0.0440 mL, 0.318 mmol) in dichloromethane (0.5 mL) . The reaction was removed the ice bath and stirred at room temperature for 14 hours. The reaction was adsorbed directly onto Ceiite5and purified by flash column chromatography using ethyl acetate / hexanes as eluent followed by trituration with dichloromethane / hexanes to provide the title compound as a white solid (0.0666 g, 56%) .The following compounds were prepared in like manner to the procedure outlined in Example 18:trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(4-(trifluoromethoxv)phenyl)benzamide (F147)CIIsolated as a yellow solid (0.078 g, 60%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(4-(dif1uoromethoxy)phenyl)benzamide (F148)CIIsolated as a light brown solid (0.089 g, 70%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-A-(4-(methylthio)phenyl)benzamide (F149)CIIsolated as a light brown solid (0.068 g, 56%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(2-fluoro-4-methoxyphenyl)benzamide (F150)CIIsolated as a beige solid (0.060 g, 49%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamldo)- / V-(2-f1uoro-4-methyl phenyl )benzamide (F151)Isolated as a white solid (0.057 g, 48%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamldo)-v-(4-(methylcarbamoyl)phenyl)benzamide (F152)Chi,Isolated as a white solid (0.062 g, 50%).trans-W-(4-Acetamidophenyl)-2-chloro-5-(2,2-dlchloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)benzamlde (F153)Chi,Isolated as a white solid (0.096 g, 77%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamldo)-v-(3,5-difluorophenyl)benzamide (F154)CIIsolated as a white solid (0.044 g, 37%).trans-2,2-Dichloro- / V-(4-chloro-3-(5-f1uoroindoline-l-carbonyl)phenyl)-3-(3,5 dichlorophenyl)cyclopropane-l-carboxamide (F155)Isolated as a white foam (0.052 g, 41%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(2-fluoropyridln-3-yl )benzamide (F 156)Isolated as a white solid (0.058 g, 48%).Example 19: Preparation of frans-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)-A -(4-fluorophenyl )-2- (methylsulfonyl )benzamlde (F 157)To a solution of trans-5-(2,2-dichloro-3-(3, 5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)-2-(methylthio)benzamide ( F 115) (0.049 g, 0.088 mmol) in dichloromethane (0.878 mL) was added mefa-chloroperoxybenzoic acid (0.049 g, 0.22 mmol) . The reaction was stirred at room temperature for 3 hours. Saturated aqueous sodium bicarbonate was added, and the mixture was extracted with ethyl acetate. The combined organic phases were washed with brine, dried over magnesium sulfate, filtered, and concentrated . Purification by flash column chromatography using 0- 15% methanol / dichloromethane as eluent provided the title compound as a white solid (0.042 g, 73%) .Example 20: Preparation of trans-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)- / V-(4-fluorophenyl )-2- (methylsulflnyl )benzamide ( F158)CI CITo a solution of trans-5-(2,2-dichloro-3-(3, 5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)-2-(methylthio)benzamide (F 115) (0.051 g, 0.091 mmol) in dichloromethane (0.9 mL) was added meta-chloroperoxybenzoic acid (0.021 g, 0.096 mmol). The reaction was stirred at room temperature for 1 hour. Saturated aqueous sodium bicarbonate was added, and the mixture was extracted with ethyl acetate. The combined organic phases were washed with brine, dried over magnesium sulfate, filtered, and concentrated . Purification by flash column chromatography using 0- 15% methanol / dichloromethane as eluent provided the title compound as a white solid (0.036 g„ 65%) .The following compounds were prepared in like manner to the procedure outlined in Example 20:trans-2-Chloro-5-( 2,2-dlchloro-3-(3f5-dichlorophenyl )cyclopropane-l- carboxamldo)- v-(4-(methylsulfInyl )phenyl )benzamide (F159)Isolated as a white solid (0.013 g, 24%) .Example 21: Preparation of trans-2-chloro-5-(2,2-dichloro-3-(3,dichlorophenyl )cyclopropane-l-carboxamido)benzoyl chlorideTo a solution of trans-2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropanecarboxamido)benzoic acid (C67) (0.200 g, 0.441 mmol) in dichloromethane (2.2 mL) stirred at 0 °C was added Ν, Ν-dimethylformamide ( 1 drop)followed by oxalyl chloride (0.0579 ml_, 0.661 mmol) over 2 minutes. The ice batch was removed, and the reaction allowed to warm to room temperature over 90 minutes. The reaction was then concentrated to provide the title compound as a cream colored foam which was used without further purification or characterization (0.211 g, quant) .Example 22: Preparation of 5-amino-2-chloro-A / -(4-fluorophenyl )benzamide (C69) and 3-amino- / V-(4-fluorophenyl )benzamlde (C70)C70Palladium on alumina (5%, 0.0065 g, 0.061 mmol) was added to a deoxygenated solution of 2-chloro- / V-(4-fluorophenyl)-5-nitrobenzamide (C143) (0. 18 g, 0.61 mmol) in ethyl acetate (6 mL) at room temperature. The mixture was purged with nitrogen, and the reaction was stirred under a balloon of hydrogen at room temperature for 3 hours. Palladium on carbon ( 10%, 0.0070 g) was added, and the reaction was stirred under a balloon of hydrogen overnight. The reaction was diluted with dichloromethane, and the reaction was washed with hydrochloric acid ( 1 N) . The aqueous layer was neutralized with saturated aqueous sodium bicarbonate and extracted with dichloromethane to provide (C69) as a yellow oil (0.028 g, 16%) : Ή N R (400 MHz, CDCb) δ 8.09 (s, 1H), 7.65 - 7.51 (m, 2H), 7.17 (d, J = 8.6 Hz, 1H), 7.08 - 7.00 (m, 3H), 6.68 (dd, J = 8.6, 2.9 Hz, 1 H), 3.85 (s, 2H) ; IR (thin film) 3349, 1654 cm1; ESIMS m / z 265 ( [M + H ]+). The organic layer was concentrated to a give a yellow solid, which was suspended in degassed methanol (6 mL). Palladium on carbon ( 10%, 0.010 g) was added, and the reaction was stirred under a balloon of hydrogen overnight. The reaction was diluted with ethyl acetate and extracted with hydrochloric acid ( 1 N ). The aqueous layer was basified with saturated aqueous sodium bicarbonate, extracted with dichloromethane, and concentrated to provide (C70) as a yellow solid (0.060 g, 38%) : Ή N MR (400 MHz, CDCb) 5 7.85 (s, 1H), 7.58 (dd, J = 9.0, 4.8 Hz, 2H), 7.25 - 7.20 (m, 1H), 7.20 - 7.15(m, 1 H), 7.04 (t, J = 8.7 Hz, 2H), 6.83 (ddd, J = 7.9, 2.4, 0.9 Hz, 1H), 3.83 (s, 2H) ; IR (thin film) 3328, 1648 cnr1; ESIMS m / z 231 ([M + H]+).Example 23: Preparation of 5-amino-2-chloro- / V-(4-f1uorophenyl )benzamide (C69)CITo a solution of 2 -chloro- V-(4-fluorophenyl)-5-nitrobenzamide (C143) (3.57 g, 12.1 mmol) in methanol (81 mL) and water (40.4 mL) was added iron powder (3.38 g, 60.6 mmol) and ammonium chloride ( 1.94 g, 36.3 mmol). The reaction was heated at 60 °C for 2 hours. The reaction was filtered through Celite - . The filtrate was diluted with ethyl acetate and washed with brine. The organic phase was extracted with hydrochloric acid ( 1 N ). The combined aqueous phases were neutralized with saturated aqueous sodium bicarbonate and extracted with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered, and concentrated to provide the title compound as a white solid ( 1.75 g, 54%) .The following compounds were prepared in like manner to the procedure outlined in Example 23 :5-Amino- / V-(4-fluorophenyl )-2-(trifluoromethyl )benzamide (C71 )FFIsolated as a brown solid (0.182 g, 63%) : Ή NM R (400 MHz, DMSO-c / e) δ 10.47 (s, 1H), 7.79 - 7.62 (m, 2H), 7.41 (d, J = 8.3 Hz, 1H), 7.18 (t, J = 8.9 Hz, 2H), 6.77 - 6.62 (m, 2H), 6.06 (s, 2H); EIMS m / z 298 ( [M]+).5-Amino-A / -(4-fluorophenyl )-2-iodobenzamide (C72)Isolated as a brown solid (0.205 g, 84%) : »H NM R (400 MHz, DMSO- / e) δ 10.34 (s, 1H), 7.78 - 7.66 (m, 2H), 7.45 (d, J = 8.5 Hz, 1H), 7.24 - 7.10 ( m, 2H), 6.67 (d, J =2.7 Hz, 1H), 6.45 (dd, J = 8.5, 2.7 Hz, 1H), 5.50 (s, 2H); IR (thin film) 3247, 1650 cm"1; ESI S m / z 357 ([ + H]+).5-Amino-2-chloro-A-(4-cyanophenyl)benzamide (C73)XIH->NIsolated as a yellow solid (0.119 g, 52%): Ή NMR (400 MHz, DMSO-c / e) δ 10.83 (s, 1H), 7.90 (d, J = 8.7 Hz, 2H), 7.81 (d, J = 8.8 Hz, 2H), 7.15 (d, J = 8.6 Hz, 1H), 6.71 (d, J = 2.7 Hz, 1H), 6.67 (dd, J = 8.6, 2.7 Hz, 1H), 5.51 (s, 2H); IR (thin film) 3365, 3100, 2223, 1670 cm"1; ESIMS m / z 273 ([M + H]+).5-Amino-2-chloro-v-(4-(trif1uoromethyl)phenyl)benzamide (C74)XIH7NIsolated as a yellow solid (0.253 g, 79%): Ή NMR (400 MHz, DMSO-de) δ 10.76 (s, 1H), 7.93 (d, J = 8.5 Hz, 2H), 7.72 (d, J = 8.6 Hz, 2H), 7.15 (d, J = 8.6 Hz, 1H), 6.72 (d, J = 2.7 Hz, 1H), 6.67 (dd, J = 8.6, 2.7 Hz, 1H), 5.51 (s, 2H); IR (thin film) 3230, 3039, 1666 cm1; ESIMS m / z 316 ([M+H]+).5-Amino-2-chloro-A-(4-chlorophenyl)benzamide (C75)XIH?NIsolated as a yellow solid (0.290 g, 90%): Ή NMR (400 MHz, DMSO- / e) δ 10.51 (s, 1H), 7.80 - 7.68 (m, 2H), 7.44 - 7.32 (m, 2H), 7.13 (d, J = 8.6 Hz, 1H), 6.69 (d, J = 2.7 Hz, 1H), 6.65 (dd, J = 8.6, 2.8 Hz, 1H), 5.48 (s, 2H); IR (thin film) 3375, 3212, 1660 cm"1; ESIMS m / z 282 ([M + H]+).5-Amino-2-chloro-A-(2-chloro-4-fluorophenyl)benzamide (C76)XIIsolated as a white solid (0.092 g, 68%): IR (thin film) 3377, 3157, 1659 cm"1; ESI S m / z 300 ([ + H]+).5-Amino-2-chloro-A / -(4-chlorophenyl)benzamide (C77)XIIsolated as a red solid (0.185 g, 84%): *H NMR (400 MHz, DMSO-de) δ 9.82 (s, 1H), 7.35 (d, J = 7.5 Hz, 1H), 7.26 - 7.10 (m, 4H), 6.75 (d, J = 2.7 Hz, 1H), 6.63 (dd, J = 8.6, 2.7 Hz, 1H), 5.46 (s, 2H), 2.27 (s, 3H); IR (thin film) 3351, 3228, 1654cm"1; ESIMS m / z 262 ([M + H]+).5-Amino-v-(4-fluorophenyl)-2-methylbenzamide (C78)XH3H7NIsolated as a brown solid (0.390 g, 83%): Ή NMR (400 MHz, DMSO-de) δ 10.23 (s, 1H), 7.82 - 7.68 (m, 2H), 7.23 - 7.08 (m, 2H), 6.92 (d, J = 8.2 Hz, 1H), 6.65 (d, J■■ 2.4 Hz, 1H), 6.58 (dd, J = 8.1, 2.4 Hz, 1H), 5.07 (s, 2H), 2.18 (s, 3H); IR (thin film) 3422, 3339, 3256, 1649 cm"1; ESIMS m / z 245 ([M + H]+).5-Amino-2-bromo-A-(4-fluorophenyl)benzamide (C79).BrIsolated as a brown solid (0.308 g, 87%): Ή NMR (400 MHz, DMSO-c / e) δ 10.40 (s, 1H), 7.76 - 7.66 (m, 2H), 7.26 (d, J = 8.6 Hz, 1H), 7.21 - 7.11 (m, 2H), 6.68 (d, J = 2.7 Hz, 1H), 6.58 (dd, J = 8.6, 2.8 Hz, 1H), 5.50 (s, 2H); IR (thin film) 3382, 3236, 1645 cm1; ESIMS m / z 310 ([M + H]+).5-Amino- / V-(4-fluorophenyl)-2-(lH-l,2,4-triazol-l-yl)benzamide (C80)N■Isolated as a beige solid (0.182 g, 54%): Ή NMR (400 MHz, DMSO-de) δ 10.32 (s, 1H), 8.63 (s, 1H), 7.99 (s, 1H), 7.597.51 (m, 2H), 7.24 (d, J = 8.5 Hz, 1H), 7.15 - 7.08 (m, 2H), 6.81 (d, J = 2.5 Hz, 1H), 6.74 (dd, J = 8.5, 2.5 Hz, 1H), 5.75 (s, 2H); IR (thin film) 3344, 3227, 3051, 1659 cm1; ESIMS m / z 298 ([M + H]+).4-Amino-V-(4-fluorophenyl)picolinamide (C81)FIsolated as a brown solid (0.321 g, 57%): Ή NMR (400 MHz, DMSO-de) δ 10.53 (s, 1H), 8.11 (d, J = 5.5 Hz, 1H), 7.91 (dd, J = 9.0, 5.0 Hz, 2H), 7.32 (d, J = 2.1 Hz, 1H), 7.18 (t, J = 8.9 Hz, 2H), 6.66 (dd, J = 5.5, 2.2 Hz, 1H), 6.44 (s, 2H); IR (thin film) 3484, 3359, 3321, 3234, 1642 cm"1; ESIMS m / z 232 ([M + H]+).3-Amino-2-chloro-W-(4-f1uorophenyl)benzamlde (C82)Isolated as a yellow solid (0.332 g, 65%): Ή NMR (400 MHz, DMSO-?6) δ 10.42 (s, 1H), 7.81 - 7.65 (m, 2H), 7.257.13 (m, 2H), 7.10 (t, J = 7.7 Hz, 1H), 6.88 (dd, J = 8.1, 1.3 Hz, 1H), 6.67 (dd, J = 7.3, 1.3 Hz, 1H), 5.57 (s, 2H); IR (thin film) 3372, 3237, 3011, 1655 cm"1; ESIMS m / z 265 ([M + H]+).5-Amino-A-(4-fluorophenyl)-2-methoxybenzamide (C83)Isolated as a light brown solid (0.356 g, 61%): Ή NMR (400 MHz, DMSO-c / e) δ 10.12 (s, 1H), 7.80 - 7.69 (m, 2H), 7.217.11 (m, 2H), 6.96 (d, J = 2.9 Hz, 1H), 6.90 (d, J = 8.8 Hz, 1H), 6.71 (dd, J = 8.7, 2.9 Hz, 1H), 4.89 (s, 2H), 3.79 (s, 3H); IR (thin film) 3338, 1662 cm1; ESIMS m / z 261 ([M + H]+).5-Amino-2-chloro-A-phenylbenzamide (C84)Isolated as a white foam (1.28 g, 96%): Ή N R (400 MHz, CDCb) δ 7.97 (s, 1H), 7.68 - 7.60 (m, 2H), 7.43 - 7.34 (m, 2H), 7.22 - 7.13 (m, 2H), 7.10 (d, J = 2.9 Hz, 1H), 6.71 (dd, J = 8.5, 2.9 Hz, 1H), 3.83 (s, 2H);13C NMR (101 MHz, CDCb) δ 164.43, 145.71, 137.61, 135.33, 131.12, 129.12, 124.77, 120.12, 118.92, 118.22, 116.55; ESIMS m / z 247 ([M + H]+).5-Amino-2-chloro-W-(2-f1uorophenyl)benzamlde (C85)Isolated as a white solid (1.24 g, quant): Ή NMR (400 MHz, CDCb) δ 8.48 (td, J = 8.1, 1.6 Hz, 1H), 8.34 (s, 1H), 7.23 - 7.08 (m, 5H), 6.72 (dd, J = 8.5, 2.9 Hz, 1H), 3.85 (s, 2H), 3.48 (s, 1H);19F NMR (376 MHz, CDCb) δ -130.65; ESIMS m / z 265 ([M + H]+).5-Amino-2-chloro-v-(2,4-difluorophenyl)benzamlde (C86)FIsolated as a purple solid (0.37 g, 28%): Ή NMR (400 MHz, CDCb) δ 8.42 (tdd, J = 9.7, 6.0, 3.6 Hz, 1H), 8.25 (s, 1H), 7.21 (d, J = 8.5 Hz, 1H), 7.13 (d, J = 2.9 Hz, 1H), 6.97 - 6.88 (m, 2H), 6.73 (dd, J = 8.5, 2.9 Hz, 1H), 3.84 (s, 2H);15F NMR (376 MHz, CDCb) δ -114.57 (d, J = 4.6 Hz), -125.78 (d, J = 4.6 Hz); ESIMS m / z 283 ([M + H]+). 5-Amino-2-chloro-W-(4-fluorophenyl)-W-methylbenzamlde (C87)FIsolated as a white solid (0.81 g, 60%): Ή NMR (400 MHz, CDCb) δ 7.17 - 7.07(m, 2H), 6.96 - 6.83 (m, 3H), 6.49 - 6.40 (m, 2H), 3.60 (s, 2H), 3.45 (s, 3H);19F NMR (376 MHz, CDCb) δ -114.12; ESIMS m / z 279 ([M + H]+).5-Amino-2-chloro-A-(3-fluorophenyl)benzamide (C88)Isolated as a white solid (1.18 g, 95%): Ή NMR (400 MHz, CDC ) δ 8.05 (s, 1H), 7.63 (dt, J = 10.9, 2.2 Hz, 1H), 7.31 (td, J = 8.1, 6.2 Hz, 1H), 7.26 - 7.22 (m, 1H), 7.20 (d, J = 8.5 Hz, 1H), 7.09 (d, J = 3.0 Hz, 1H), 6.86 (tdd, J = 8.3, 2.5, 1.1 Hz, 1H), 6.71 (dd, J = 8.6, 2.9 Hz, 1H), 3.84 (s, 2H);19F NMR (376 MHz, CDCb) δ -111.22; ESIMS m / z 265 ([M + H]+).5-Amino-2-chloro-W-(3-cyanophenyl)benzamide (C89)XIH-.NIsolated as a white solid (0.89 g, 70%): Ή NMR (400 MHz, DMSO-de) δ 10.75 (s, 1H), 8.23 - 8.14 (m, 1H), 7.95 (td, J = 4.7, 2.2 Hz, 1H), 7.66 - 7.50 (m, 2H), 7.15 (d, J = 8.6 Hz, 1H), 6.76 - 6.60 (m, 2H), 5.52 (s, 2H);I3C NMR (101 MHz, DMSO-c / e) δ 165.98, 147.85, 139.77, 136.41, 130.29, 129.99, 127.17, 123.96, 121.98, 118.63, 116.18, 115.03, 113.32, 111.60; ESIMS m / z 272 ([M + H]+).5-Amino-2-chloro-v-(2,3-difluorophenyl)benzamlde (C90)XIH,NIsolated as a white solid (1.11 g, 99%): Ή NMR (400 MHz, CDCb) δ 8.38 (s, 1H), 8.29 - 8.20 (m, 1H), 7.22 (d, J = 8.6 Hz, 1H), 7.17 - 7.06 (m, 2H), 6.95 (dddd, J = 9.9, 8.6, 7.6, 1.5 Hz, 1H), 6.73 (dd, J = 8.6, 2.9 Hz, 1H), 3.85 (s, 2H);19F NMR (376 MHz, CDCb) δ -137.88 (d, J = 20.5 Hz), -154.65 (d, J = 20.4 Hz); ESIMS m / z 283 ([M + H]+). 5-Amino-2-chloro-A-(3,4-difluorophenyl)benzamide (C91)XIIsolated as a grey solid (1.26 g, 93%): Ή NMR (400 MHz, CDCb) δ 8.03 (s, 1H), 7.76 (ddd, J = 12.1, 7.2, 2.3 Hz, 1H), 7.23 - 7.08 (m, 4H), 6.72 (dd, J = 8.6, 2.9 Hz, 1H), 3.85 (s, 2H);19F NMR (376 MHz, CDCb) δ -135.39 (d, J = 21.6 Hz), -141.93 (d, J = 21.7 Hz); ESIMS m / z 283 ([M + H]+).5-Amino-2-chloro- / V-(2,4,6-trifluorophenyl)benzamlde (C92)Isolated as a light brown solid (1.20 g, 73%): Ή NMR (400 MHz, DMSO-c / e) δ 10.08 (s, 1H), 7.38 - 7.27 (m, 2H), 7.14 (d, J = 8.6 Hz, 1H), 6.74 (d, J = 2.7 Hz, 1H), 6.65 (dd, J = 8.6, 2.8 Hz, 1H), 5.52 (s, 2H);19F NMR (376 MHz, DMSO-de) δ -109.56 (t, J = 5.5 Hz), -114.48 (d, J = 5.5 Hz); ESIMS m / z 301 ([M + H]+).5-Amino-2-chloro-v-(2,6-difluorophenyl)benzamide (C93)XIIsolated as a light brown solid (0.93 g, 98%): Ή NMR (400 MHz, DMSO-de) δ 10.09 (s, 1H), 7.40 (tt, J = 8.4, 6.3 Hz, 1H), 7.26 - 7.10 (m, 3H), 6.75 (d, J = 2.7 Hz, 1H), 6.65 (dd, J = 8.6, 2.8 Hz, 1H), 5.51 (s, 2H);I9F NMR (376 MHz, DMSO-c / e) δ - 117.62; ESIMS m / z 283 ([M + H]+).3-Amino-4-chloro-N-(4-f1uorophenyl)benzamlde (C94)CI-H7NIsolated as a white solid (0.147 g, 23%): Ή NMR (400 MHz, DMSO-de) δ 10.21 (s, 1H), 7.83 - 7.69 (m, 2H), 7.39 - 7.27 (m, 2H), 7.23 - 7.14 (m, 2H), 7.10 (dd, J = 8.3, 2.1 Hz, 1H), 5.61 (s, 2H); IR (thin film) 3472, 3379, 1659 cm"1; ESIMS m / z 265 ([M + H]+).5-Amino-2-chloro-N-(pyridin-4-yl)benzamide (C95)XIH7NIsolated as a yellow solid (0.385 g, 89%): Ή NMR (400 MHz, CD3OD) δ 8.44 (dt, J = 5.0, 1.3 Hz, 2H), 7.78 - 7.71 (m, 2H), 7.17 (dd, J = 8.6, 1.2 Hz, 1H), 6.83 (dd, J = 2.8, 1.1 Hz, 1H), 6.77 (ddd, J = 8.6, 2.8, 1.1 Hz, 1H);I3C NMR (101 MHz, CDC ) δ 171.98, 153.55, 153.30, 151.33, 150.57, 140.02, 134.02, 121.26, 117.90; ESIMS m / z 248 ([M + H]+).5-Amino-2-chloro-A -(pyridin-3-yl )benzamide (C96)CIIsolated as a yellow solid (0.341 g, 80%) : Ή N MR (400 MHz, CDBOD) δ 8.82 (d, J = 2.5 Hz, 1H), 8.31 (dt, J = 4.9, 1.2 Hz, 1H ), 8.23 (ddt, J = 8.4, 2.6, 1.2 Hz, 1H), 7.45 (dd, J = 8.4, 4.9 Hz, 1H), 7.17 (dd, J = 8.6, 1.0 Hz, 1H), 6.85 (dd, J = 2.7, 1.0 Hz, 1H), 6.77 (ddd, J = 8.7, 2.8, 1.0 Hz, 1H);13C NM R ( 126 MHz, CD3OD) δ 167.78, 147.36, 144.18, 140.67, 136. 19, 135.99, 130.06, 127.82, 123.97, 117.41, 117.22, 114.04; ESIMS m / z 248 ( [M + H]+).3-Amino- / V-(4-fluorophenvl )-2-methoxybenzamide (C97)Isolated as a yellow oil (0.541 g, quant) : »H N MR (400 MHz, CDC ) δ 9.61 (s, 1H), 7.69 - 7.61 (m, 2H), 7.50 (dd, J = 7.8, 1.6 Hz, 1 H), 7.13 - 7.02 (m, 3H), 6.92 (dd, J = 7.8, 1.6 Hz, 1H), 3.93 (s, 2H), 3.87 (s, 3H);19F NM R (376 MHz, CDCI3) δ -118.16; ESIMS m / z 261 ( [M + H]+).5-Amino-2-chloro- v-(2-chloropyridin-3-yl )benzamide (C98)CIIsolated as a yellow solid (0.269 g, 83%) : Ή N MR (400 MHz, DMSO-de) δ 10.25 (s, 1H), 8.30 (dd, J = 4.7, 1.8 Hz, 1H), 8.09 (d, J = 8. 1 Hz, 1H), 7.49 (dd, J = 7.9, 4.7 Hz, 1H), 7.14 (d, J = 8.6 Hz, 1H), 6.79 (d, J = 2.8 Hz, 1H), 6.66 (dd, J = 8.6, 2.7 Hz, 1H), 5.51 (s, 2H);l3C N MR ( 101 MHz, DMSO-de) δ 165.98, 147.76, 146.42, 145.29, 135.89, 135.82, 131.61, 129.99, 123.44, 116.25, 115.23, 113.61 ; ESIMS m / z 282 ( [M + H]+).5-Amino-2-chloro-W-(6-chloropyridin-3-yl )benzamide (C99)CIIsolated as a yellow solid (0.560 g, 69%) : Ή N MR (400 MHz, DMSO- ?6) δ 10.77 (s, 1H), 8.72 (d, J = 2.7 Hz, 1H), 8.19 (dd, J = 8.7, 2.7 Hz, 1H), 7.52 (d, J = 8.7 Hz,1H), 7.16 (d, J = 8.6 Hz, 1H), 6.73 (d, J = 2.7 Hz, 1H), 6.68 (dd, J = 8.6, 2.8 Hz, 1H), 5.52 (s, 2H);13C NMR (101 MHz, DMSO-de) δ 165.95, 147.84, 143.95, 140.56, 136.17, 135.28, 130.02, 129.94, 124.27, 116.25, 115.04, 113.36; ESIMS m / z 282 ([M + H]+). 5-Amino-2-chloro-A / -(6-cyanopyridin-3-yl)benzamide (CIOO)XIH7NIsolated as a yellow solid (0.292 g, 45%): Ή NMR (400 MHz, DMSO-?6) δ 11.10 (s, 1H), 8.98 (d, J = 2.5 Hz, 1H), 8.38 (dd, J = 8.6, 2.6 Hz, 1H), 8.03 (d, J = 8.7 Hz, 1H), 7.17 (d, J = 8.6 Hz, 1H), 6.74 (d, J = 2.7 Hz, 1H), 6.69 (dd, J = 8.6, 2.8 Hz, 1H), 5.54 (d, J = 9.0 Hz, 2H);13C NMR (101 MHz, DMSO-de) δ 166.45, 147.89, 142.08, 138.85, 135.78, 130.11, 129.70, 126.37, 126.12, 117.64, 116.48, 114.98, 113.33; ESIMS m / z 273 ([M + H]+).5-Amino-2-chloro-A-(3-fluorophenyl)-A / -methylbenzamide (ClOl)XIIsolated as a yellow oil (0.446 g, 99%): Ή NMR (400 MHz, CDC ) δ 7.16 (d, J = 7.9 Hz, 2H), 7.03 - 6.77 (m, 4H), 6.47 (s, 2H), 3.61 (s, 2H), 3.47 (s, 3H);19F NMR (376 MHz, CDCb) δ -111.45; ESIMS m / z 279 ([M + H]+).5-Amino-2-chloro- / V-(2-fluorophenyl)-v-methylbenzamide (C102)XIH7NIsolated as a red-orange oil (0.542 g, quant): Ή NMR (400 MHz, CDCb) δ 7.26 - 7.13 (m, 2H), 7.04 - 6.94 (m, 2H), 6.91 (d, J = 8.6 Hz, 1H), 6.52 (dd, J = 2.8, 1.4 Hz, 1H), 6.41 (dd, J = 8.6, 2.8 Hz, 1H), 3.59 (s, 2H), 3.42 (d, J = 0.6 Hz, 3H);19F NMR (376 MHz, CDCb) δ -120.54; ESIMS m / z 279 ([M + H]+).5-Amino-2-chloro-v-(4-cyano-2-methylphenyl)benzamlde (C103)XIIsolated as a white solid (0.390 g, 86%): Ή NMR (400 MHz, CDCb) δ 8.43 (d, J = 8.6 Hz, 1H), 8.23 (s, 1H), 7.57 (dd, J = 8.5, 2.0 Hz, 1H), 7.50 (d, J = 1.9 Hz, 1H), 7.22 (d, J = 8.6 Hz, 1H), 7.19 (d, J = 2.9 Hz, 1H), 6.75 (dd, J = 8.6, 2.9 Hz, 1H), 3.88 (s, 2H), 2.38 (s, 3H);13C NMR (101 MHz, CDCb) δ 145.97, 140.12, 134.26, 134.01, 131.35, 131.27, 128.18, 121.64, 118.89, 118.76, 118.44, 117.09, 107.72, 17.93;ESIMS m / z 286 ([M + H]+).5-Amino-2-chloro- / V-(4-f1uoro-2-methyl phenyl )benzamide (C104)CIIsolated as a red solid (0.430 g, 95%): >H NMR (400 MHz, DMSO-de) δ 9.84 (s, 1H), 7.34 (dd, J = 8.8, 5.7 Hz, 1H), 7.12 (dd, J = 9.0, 2.4 Hz, 2H), 7.04 (td, J = 8.6, 3.0 Hz, 1H), 6.74 (d, J = 2.7 Hz, 1H), 6.63 (dd, J = 8.6, 2.8 Hz, 1H), 5.46 (s, 2H), 2.27 (s, 3H);19F NMR (376 MHz, DMSO-de) δ -117.12; ESIMS m / z 279 ([M + H]+).6-Amino-A-(4-fluorophenyl)picolinamide (C105)Isolated as a green film (0.072 g, 15%): Ή NMR (400 MHz, CDCb) δ 9.82 (s, 1H), 7.70 (dd, J = 7.2, 4.8 Hz, 2H), 7.67 - 7.52 (m, 2H), 7.05 (t, J = 8.3 Hz, 2H), 6.67 (d, J = 7.6 Hz, 1H), 4.63 (s, 2H); IR (thin film) 3333, 1671, 1608 cnr1; ESIMS m / z 232 ([M + H]+).3-Amino- / V-(4-fluorophenyl)-4-methylbenzamide (C106)FIsolated as a faint yellow solid (0.102 g, 15%): Ή NMR (400 MHz, DMSO-de) δ 10.05 (s, 1H), 7.82 - 7.71 (m, 2H), 7.20 - 7.11 (m, 3H), 7.09 - 7.01 (m, 2H), 5.07 (s, 2H), 2.11 (s, 3H); IR (thin film) 3366, 2924, 1655 cm"1; ESIMS m / z 245 ([M + H]+). 5-Amino-A-(4-fluorophenyl)-2-(trlf1uoromethoxy)benzamide (CI 07)FF. FOFIsolated as a white solid (0.448 g, 81%): mp 115-117 °C; Ή NMR (400 MHz, DMSO-de) δ 10.39 (s, 1H), 7.76 - 7.64 (m, 2H), 7.23 - 7.15 (m, 2H), 7.10 (d, J = 8.9 Hz, 1H), 6.76 (d, J = 2.8 Hz, 1H), 6.70 (dd, J = 8.8, 2.8 Hz, 1H), 5.57 (s, 2H); ESIMS m / z 315 ([M + H]+).3-Amino-5-chloro- / V-(4-fluorophenyl)benzamide (C108)CIFIsolated as a light brown solid (0.497 g, 81%): mp 133-136 °C; Ή NMR (400 MHz, DMSO-de) δ 10.23 (d, J = 8.3 Hz, 1H), 7.82 - 7.68 (m, 2H), 7.25 - 7.12 (m, 2H), 7.10 - 7.00 (m, 2H), 6.76 (t, J = 2.0 Hz, 1H), 5.69 (s, 2H); ESIMS m / z 265 ([M]+). 5-Amino-2-chloro-A / -(2-chlorophenyl)benzamide (C109)Isolated as a red oil (0.391 g, 69%): Ή NMR (400 MHz, CDCb) δ 8.60 - 8.53 (m, 2H), 7.41 (dd, J = 8.0, 1.5 Hz, 1H), 7.33 (td, J = 8.0, 1.6 Hz, 1H), 7.22 (d, J = 8.5 Hz, 1H), 7.13 (dd, J = 6.1, 2.2 Hz, 1H), 7.09 (td, J = 7.8, 1.6 Hz, 1H), 6.73 (dd, J = 8.6, 2.9 Hz, 1H), 3.85 (s, 2H);13C NMR (101 MHz, CDCIs) δ 145.70, 134.98, 131.82, 131.30, 129.17, 127.77, 126.29, 125.00, 122.04, 121.82, 118.45, 116.57; ESIMS m / z 281 ([M + H]+).5-Amino-2-chloro-v-(2-isopropyl phenyl )benzamide (CI 10)Isolated as a red oil (0.461 g, 81%): Ή NMR (400 MHz, CDCb) δ 7.92 (s, 1H), 7.85 (dd, J = 7.5, 1.9 Hz, 1H), 7.34 (dd, J = 7.2, 2.2 Hz, 1H), 7.29 - 7.18 (m, 3H), 7.17 (d, J = 2.9 Hz, 1H), 6.71 (dd, J = 8.6, 2.9 Hz, 1H), 3.84 (s, 2H), 3.16 (hept, J = 6.9 Hz,1H), 1.27 (d, J = 6.8 Hz, 6H);13C NMR (101 MHz, CDCb) δ 162.79, 145.76, 140.95, 133.86, 131.14, 126.46, 126.40, 125.71, 124.85, 118.20, 116.87, 28.04, 23.22; ESIMS m / z 289 ([M + H]+).5-Amino-2-chloro-A / -(2-ethyl-6-methyl phenyl )benzamide (CI 11)Isolated as a red oil (0.512 g, 74%): Ή NMR (400 MHz, CDCb) δ 7.57 (s, 1H), 7.25 - 7.10 (m, 5H), 6.71 (dd, J = 8.6, 2.9 Hz, 1H), 3.83 (s, 2H), 2.70 (q, J = 7.6 Hz, 2H), 2.34 (s, 3H), 1.22 (t, J = 7.6 Hz, 3H);13C NMR (101 MHz, CDC ) δ 161.01, 145.71, 144.07, 141.41, 136.23, 135.17, 131.13, 128.40, 127.96, 126.51, 118.95, 118.13, 116.80, 25.18, 18.86, 14.74; ESIMS m / z 289 ([M + H]+).5-Amino-2-chloro-A / -(3-chlorophenyl)benzamide (CI 12)CIIsolated as an orange solid (0.470 g, 62%): Ή NMR (400 MHz, CDCb) δ 8.02 (d, J = 8.1 Hz, 1H), 7.76 (dt, 3 = 3.8, 2.1 Hz, 1H), 7.53 - 7.43 (m, 1H), 7.34 - 7.28 (m, 1H), 7.19 (d, 3 = 8.5 Hz, 1H), 7.14 (ddd, 3 = 8.0, 2.0, 1.0 Hz, 1H), 7.07 (d, 3 = 2.9 Hz, 1H), 6.71 (dd, 3 = 8.6, 2.9 Hz, 1H), 3.84 (s, 2H); ESIMS m / z 281 ([M + H]+).5-Amino-2-chloro-A / -(2,4-difluorophenyl)- / V-methylbenzamide (CI 13)Isolated as a yellow foam (0.495 g, 91%): Ή NMR (300 MHz, CDCb) δ 6.93 (d, J= 8.6 Hz, 1H), 6.82 - 6.64 (m, 3H), 6.52 (d, J = 2.6 Hz, 1H), 6.44 (dd, J = 8.6, 2.8 Hz, 1H), 3.62 (s, 2H), 3.39 (s, 3H); IR (thin film) 3355, 1645, 1510 cm'1; ESIMS m / z 297 ([M + H]+).5-Amino-2-chloro-4-fluoro-v-(4-fluorophenyl)benzamide (CI 14)Isolated as a yellow foam (0.442 g, 95%): Ή NMR (300 MHz, DMSO- / e) δ 10.44 (s, 1H), 7.87 - 7.63 (m, 2H), 7.28 (d, J = 11.2 Hz, 1H), 7.24 - 7.12 (m, 2H), 6.92 (d, J = 9.4 Hz, 1H), 5.56 (s, 2H); ESIMS m / z 283 ([M + H]+).5-Amino-2-chloro-A-(5-fIuoropyridin-2-yl)benzamide (CI 15)Isolated as a yellow solid (0.073 g, 90%): Ή NMR (400 MHz, DMSO-de) δ 10.96 (s, 1H), 8.35 (d, J = 3.1 Hz, 1H), 8.26 - 8.15 (m, 1H), 7.79 (td, J = 8.7, 3.0 Hz, 1H), 7.18 (d, J = 8.8 Hz, 1H), 6.89 - 6.73 (m, 2H), 5.44 (s, 2H);19F NMR (376 MHz, DMSO- de) δ -132.77; ESIMS m / z 266 ([M+H]+).5-(5-Amino-2-chlorobenzamido)- / V-methylpicolinamide (CI 16)Isolated as a yellow foam (0.187 g, quant): Ή NMR (400 MHz, DMSO-cfe) δ 10.86 (s, 1H), 8.92 (dd, J = 5.0, 2.4 Hz, 1H), 8.66 (d, J = 5.0 Hz, 1H), 8.30 (dt, J = 8.6, 2.3 Hz, 1H), 8.03 (dd, J = 8.6, 2.5 Hz, 1H), 7.16 (d, J = 8.6 Hz, 1H), 6.74 (d, J = 2.7 Hz, 1H), 6.68 (dd, J = 8.6, 2.7 Hz, 1H), 5.52 (s, 2H), 2.81 (d, J = 4.8 Hz, 3H); ESIMS m / z 305 ([M + H]+).5-Amino-2-chloro-A-(pyridin-2-yl)benzamide (CI 17)Isolated as a yellow foam (0.152 g, 49%): Ή NMR (400 MHz, DMSO-de) δ 11.25 (s, 1H), 8.74 (d, J = 2.7 Hz, 1H), 8.46 (d, J = 2.8 Hz, 1H), 8.41 - 8.35 (m, 1H), 8.32 (dd, J = 8.9, 2.8 Hz, 1H), 8.25 (dd, J = 8.8, 2.7 Hz, 1H), 8.20 (d, J = 8.4 Hz, 1H), 7.92 - 7.78 (m, 3H), 7.21 (ddd, J = 7.4, 4.9, 1.0 Hz, 1H); EIMS m / z 248 ([M + H]+).A / -Allyl-5-amino-2-chloro- / V-(4-f1uorophenyl)benzamide (CI 18)Η,ΝIsolated as an orange solid (0.269 g, 60%): ESIMS m / z 305 ([M + H]+).Example 24: Preparation of 5-amino-2-f1uoro-A / -(4-fIuorophenyl)benzamide (C119).FH7NTo a solution of 2-fluoro- / V-(4-fluorophenyl)-5-nitrobenzamide (C183) (1.06g, 3.81 mmol) in ethyl acetate (15 mL) under a nitrogen blanket was added palladium on carbon (0.120 g, 0.0560 mmol). The reaction flask was placed on a Parr shaker at room temperature under hydrogen (45 psi) for 16 hours. The reaction was filtered through Celite5, washed with ethyl acetate, and concentrated to provide the title product as a white solid (0.955 g, quant) *H NMR (400 MHz, CDCIs) δ 8.46 (d, J = 17.1 Hz, 1H), 7.65 - 7.58 (m, 2H), 7.42 (dd, J = 6.5, 3.1 Hz, 1H), 7.11 - 7.03 (m, 2H), 6.98 (dd, J = 11.8, 8.8 Hz, 1H), 6.78 (ddd, J = 8.7, 4.1, 3.1 Hz, 1H), 3.74 (s, 2H);19F NMR (376 MHz, CDCI3) δ -117.55, -126.58; EIMS m / z 249 ([M + H]+).The following compounds were prepared in like manner to the procedure outlined in Example 24 :3-Amino-2-fluoro-v-(4-fluorophenvl)benzamide (CI 20)H?NIsolated as a white solid (1.05 g, 96%): Ή NMR (400 MHz, CDCb) δ 8.28 (d, J 13.9 Hz, 1H), 7.66 - 7.57 (m, 2H), 7.43 (ddd, J = 7.8, 7.0, 1.7 Hz, 1H), 7.12 - 7.03 ( 3H), 6.95 (ddd, J = 8.7, 7.9, 1.7 Hz, 1H), 3.87 (s, 2H);19F NMR (376 MHz, CDCb) δ - 117.54, -136.71; EIMS m / z 249 ([M + H]+).5-Amino-2-fluoro-V-(4-fluorophenyl)-A-methylbenzamide (C121)Isolated as a white foam (0.618 g, 98%): Ή NMR (300 MHz, CDC ) δ 7.12 - 7.01 (m, 2H), 6.96 - 6.83 (m, 2H), 6.67 - 6.44 (m, 3H), 3.54 (br s, 2H), 3.44 (s, 3H); IR (thin film) 3351, 2922, 1638, 1509 cm1; ESIMS m / z 263 ([M + H]+).5-Amino-2-fluoro- / V-(3-fluorophenyl)-A / -methvlbenzamide (CI 22),FH?NIsolated as a white foam (0.595 g, quant): EIMS m / z 263 ([M + H]+).3-Amino-2-fluoro-A-(4-fluorophenyl)-A / -methylbenzamide (CI 23)IF OIsolated as a green solid (0.595 g, quant): Ή NMR (300 MHz, CDCh) δ 7.05 (s, 2H), 6.89 (t, J = 8.3 Hz, 2H), 6.77 (t, 3 = 7.7 Hz, 1H), 6.59 (dt, 3 = 13.9, 7.6 Hz, 2H), 3.62 (s, 2H), 3.45 (s, 3H); EIMS m / z 263 ([M + H]+).5-Amino-2,4-dif1uoro- / V-(4-fluorophenvl)benzamide (CI 24)Isolated as a white foam (0.436 g, 87%): »H NMR (300 MHz, CDCb) δ 8.37 (d, 3 = 16.6 Hz, 1H), 7.66 - 7.53 (m, 3H), 7.11 - 7.02 (m, 2H), 6.89 (dd, J = 11.6, 10.2 Hz, 1H), 3.79 (s, 2H); EIMS m / z 267 ([M + H]+).5-Amino-A-(2,4-difluorophenyl)-2-f1uorobenzamide (CI 25).FIsolated as a white solid (0.90 g, quant):lH NMR (400 MHz, CDCb) δ 8.71 (d, J = 17.8 Hz, 1H), 8.43 (td, J = 9.1, 6.0 Hz, 1H), 7.42 (dd, J = 6.4, 3.1 Hz, 1H), 6.99 (dd, J = 11.7, 8.7 Hz, 1H), 6.96 - 6.86 (m, 2H), 6.80 (ddd, J = 8.7, 4.1, 3.1 Hz, 1H), 3.82 (s, 2H);15F NMR (376 MHz, CDCb) δ -114.82 (d, J = 4.6 Hz), -125.88 (d, J = 4.6 Hz), - 126.34 (d, J = 1.4 Hz); EIMS m / z 267 ([M + H]+).5-Amino-A-(2,4-difluorophenyl)-2-fluoro-N-methylbenzamlde (C126)FIsolated as a brown oil (0.54 g, 57%): »H NMR (400 MHz, DMSO-c / e) δ 7.40 - 7.21 (m, 2H), 7.00 (t, J = 8.6 Hz, 1H), 6.63 (t, J = 9.1 Hz, 1H), 6.50 - 6.37 (m, 2H) 5.01 (s, 2H), 3.25 (s, 3H);19F NMR (376 MHz, DMSO-de) δ -109.77 (d, J = 7.6 Hz), 116.51 (t, J = 7.1 Hz), -131.34 (d, J = 6.2 Hz); EIMS m / z 281 ([M + H]+).5-Amino-2-fIuoro-v-methyl- / V-phenvlbenzamide (CI 27)Isolated as a white solid (0.92 g, 71%): Ή NMR (400 MHz, DMSO-ck) δ 7.40 - 7.05 (m, 5H), 6.63 (s, 1H), 6.43 (s, 2H), 4.97 (s, 2H), 3.32 (s, 3H);19F NMR (376 MHz, DMSO- / e) δ -131.23; EIMS m / z 245 ([M + H]+).3-Amino-2-fluoro-V-methyl-A-phenylbenzamide (CI 28)Isolated as a white solid (1.07 g, 87%): Ή NMR (400 MHz, DMSO-c / e) δ 7.41 7.00 (m, 5H), 6.64 (d, J = 39.8 Hz, 2H), 6.35 (s, 1H), 5.07 (s, 2H), 3.32 (s, 3H);19l NMR (376 MHz, DMSO-c / e) δ -137.79; EIMS m / z 245 ([M + H]+).5-Amino- / V-(4-cyano-2-fluorophenyl)-2-fluorobenzamide (C129)Isolated as a yellow solid (0.447 g, 95%): Ή NMR (400 MHz, DMSO-de) δ 10.32 10.14 (m, 1H), 8.17 (t, J = 8.1 Hz, 1H), 7.95 (dd, J = 10.8, 1.8 Hz, 1H), 7.72 (dt, J = 8.4, 1.2 Hz, 1H), 7.01 (dd, J = 10.5, 8.8 Hz, 1H), 6.89 (dd, J = 6.0, 2.9 Hz, 1H), 6.73 (ddd, J = 8.8, 4.2, 2.9 Hz, 1H), 5.25 (s, 2H);19F NMR (376 MHz, D SO-cfe) δ -120.96, - 130.61; EIMS m / z 274 ([M + H]+).5-Amino-2-chloro-W-ethyl-A-(4-fluorophenyl)benzamide (C130),CI ^CH3Isolated as a white solid (0.201 g, 98%): EIMS m / z 293 ([M + H]+).5-Amino-2-chloro-A-(4-fJuorophenvl)-A-(2,2,2-trlf1uoroethyl)benzamide (C131)H?NIsolated as a white solid (0.125 g, 97%): EIMS m / z 347 ([M + H]+).5-Amino-2-chloro-A-(4-fluorophenyl)-W-propvlbenzamide (C132)H,NIsolated as a white solid (0.267 g, 99%): EIMS m / z 307 ([M + H]+).5-Amino- / V-(4-cyano-2-fluorophenvl)-2-fluoro-A-methvlbenzamide (C133)-FIsolated as an orange solid (0.120 g, 22%): Ή NMR (400 MHz, CDC ) δ 7.45 - 7.17 (m, 4H), 6.70 (dd, J = 5.4, 2.8 Hz, 1H), 6.68 - 6.52 (m, 1H), 3.63 (s, 2H), 3.40 (s, 3H);19F NMR (376 MHz, CDCb) δ -116.04, -126.81; EIMS m / z 288 ([M + H]+).5-Amino-2-chloro-A-(4-cyano-2-fluorophenyl)-A / -methylbenzamide (C134)H->NIsolated as a red-orange solid (0.248 g, 33%) : EIMS m / z 304 ( [ + H]+) .Example 25: Preparation of 6-Amlno-3-chloro-A -(4-fluorophenyl )picolinamide (C135)XIStep 1. 6-[bis(tert-butoxycarbonyl )amino]-3-chloro-pyridine-2-carboxylic acid (C136) and 6-(teri-butoxycarbonylamino)-3-chloro-pyridine-2-carboxylic acid (C137):,CI .CICh OOO OH3C"CH-:CH3~C136 C137To a solution of methyl 6-[bis(tert-butoxycarbonyl)amino]-3-chloro-pyridine-2- carboxylate (C211 ) (0.500 g, 1.29 mmol) in tetrahydrofuram (6.5 mL) and water ( 1.4 mL) was added lithium hydroxide (0.0930 g, 3.88 mmol) . After 3 hours, the reaction was acidified with hydrochloric acid (0.5 N ), and the reaction mixture was extracted with ethyl acetate. The combined organic phases were washed with water, dried over magnesium sulfate, and concentrated to provide a 3 : 1 mixture of (C136) and (C 137) (0.308 g) .Step 2. terf-butyl W-tert-butoxycarbonyl- / V-[5-chloro-6-[(4- fluorophenyl )carbamoyl ]-2-pyridyl ]carbamate (C138) and teri-butyl VV-[5- chloro-6-[(4-fluorophenyl )carbamoyl]-2-pyridyl ]carbamate (C 139):C138 C1396-[Bis(ieri-butoxycarbonyl)amino]-3-chloro-pyridine-2-carboxylic acid (C136) and 6- (tert-butoxycarbonylamino)-3-chloro-pyridine-2-carboxylic acid (C 137) (0.308 g) was dissolved in 1,2-dichloroethane (3.5 mL) and 4-dimethylaminopyridine (0.165 g, 1.35 mmol), 4-fluoroaniline (0.118 mL, 1.24 mmol), and l-ethyl-3-(3- dimethylaminopropyl)carbodiimide hydrochloride (0.298 g, 1.56 mmol) were added at room temperature. The reaction was stirred at room temperature overnight. The reaction mixture was diluted with dichloromethane and washed with saturated aqueous sodium bicarbonate followed by hydrochloric acid ( 1 N) to provide a 3 : 1 mixture of (C138) and (C139) (0.537 g ) .Step 3. 6-amino-3-chloro- / V-(4-fluorophenyl )picolinamide (C135): The mixture of (C138) and (C139 ) (0.537 g) were dissolved in dichloromethane (2.4 mL), and trifluoroacetic acid (2.4 mL) was added. After 30 minutes, the reaction was poured into a separator / funnel and carefully quenched with saturated aqueous sodium bicarbonate. The mixture was extracted with dichloromethane. The combined organic phases were dried over magnesium sulfate, and concentrated to provide the title compound as a white solid (0.223 g, 0.797 mmol) : *H NM R (400 MHz, DMSO- / e) δ 10.49 (s, 1H ), 7.79 - 7.66 (m, 2H), 7.54 (d, J = 8.8 Hz, 1H ), 7.24 - 7. 14 (m, 2H), 6.58 (d, J = 8.8 Hz, 1H), 6.44 (s, 2H ); IR (thin film) 3476, 3339, 1685 cm" 1; EIMS m / z 266 ([M]+).Example 26: Preparation of 5-amino-2-chloro-A / -(4-fluorophenyl )-A / - methyl benzothioamlde (C140)To a solution of 5-amino-2-chloro-N-(4-fluorophenyl)benzamide (C69) (0.300g, 1.13 mmol ) in tetrahydrofuran (4 mL) was added 1, 1, 1,3,3,3-hexamethyldisiloxane ( 1.21 mL, 5.67 mmol) followed by phosphorus pentasulfide (0.529 g, 2.38 mmol ) in one portion. The reaction was warmed to 60 °C for 3 hours, cooled to room temperature, and filtered over a pad of Celite " . The filtrates were partitioned between ethyl acetate andwater. Brine was added until a phase cut was achieved . The phases were separated, and the organic layer adsorbed onto several scoops of Celite'5'. Purification by flash column chromatography provided the title compound as a yellow solid (0.108 g, 34%) : ESIMS m / z 295 ( [M + H]+).The following compounds were prepared in like manner to the procedure outlined in Example 26:5-Amino-2-chloro- v-(4-f1uorophenyl )benzothioamide (C141 )XIIsolated as a yellow solid (0.108 g, 34%) : ESIMS m / z 281 ( [M + H]+) .Example 27: Preparation of 5-amino-2-cyano- / V-(4-fluorophenyl )benzamide (C142)To a solution of 5-amino-2-bromo- / V-(4-fluorophenyl)benzamide (C79) (0.460 g, 1.49 mmol) in / V, / V-dimethylformamide (4.25 ml_) was added copper(I) cyanide (0.666 g, 7.44 mmol) . The reaction was degassed under vacuum, backfilled with nitrogen, capped in a 25-mL vial, and heated at 160 °C for 20 minutes in a Biotage Initiator5microwave reactor with external IR-sensor temperature monitoring from the side of the vessel. The reaction was diluted with ethyl acetate while stirring vigorously and filtered through Celite'-'washing with ethyl acetate. The filtrate was washed with brine. The organic phase was dried over magnesium sulfate, filtered, and concentrated to provide the title compound as a yellow solid (0.106 g, 24%) : Ή NM R (400 MHz, DMSO-c / e) δ 9.53 (s, 1H), 7.85 (d, J = 8.0 Hz, 1H), 7.48 - 7.42 (m, 2H), 7.37 - 7.29 (m, 2H), 6.94 (s, 1H), 6.89 (d, J = 9.0 Hz, 1H), 6.21 (s, 2H) ; ESIMS m / z 256 ([M + H]+).Example 28: Preparation of 2-chloro- / V-(4-fluorophenyl )-5-nitrobenzamide (C143)XI2-Chloro-5-nitrobenzoic acid (0.250 g, 1.24 mmol) and 4-dimethylaminopyridine (0.197 g, 1.61 mmol) were sequentially added to a stirred mixture of 4-fluoroaniline (0.141 ml, 1.49 mmol) and l-ethyl-3-(3-dimethylaminopropyl)carbodiimidehydrochloride (0.357 g, 1.86 mmol) in 1,2-dichloroethane (12.4 mL) at roomtemperature. The reaction was stirred at room temperature for 20 hours. The reaction mixture was diluted with dichloromethane and washed with saturated aqueous sodium bicarbonate followed by hydrochloric acid (1 N) to provide the title compound as a light brown solid (0.188 g, 49%): »H NMR (400 MHz, CDCb) δ 8.59 (d, J = 2.7 Hz, 1H), 8.26 (dd, J = 8.8, 2.8 Hz, 1H), 7.90 (s, 1H), 7.66 (d, J = 8.8 Hz, 1H), 7.64 - 7.57 (m, 2H), 7.15 - 7.05 (m, 2H);19F NMR (376 MHz, CDCb) δ -116.03; ESIMS m / z 295 ([M + H]+).The following compounds were prepared in like manner to the procedure outlined in Example 28:N-(4-Fluorophenyl)-5-nitro-2-(trifluoromethyl)benzamide (C144)FFIsolated as a light brown solid (0.299 g, 41%): »H NMR (400 MHz, CDCb) δ 8.52 (d, J = 2.1 Hz, 1H), 8.44 (dd, J = 8.7, 1.4 Hz, 1H), 7.99 (d, J = 8.6 Hz, 1H), 7.61 - 7.52 (m, 2H), 7.47 (s, 1H), 7.15 - 7.06 (m, 2H); EIMS m / z 328 ([M]+). / V-(4-Fluorophenyl)-2-iodo-5-nitrobenzamide (C145)FIsolated as a brown solid (0.258 g, 37%): Ή NMR (400 MHz, DMSO- e) δ 10.68 (s, 1H), 8.29 (d, J = 2.7 Hz, 1H), 8.26 (d, J = 8.6 Hz, 1H), 8.03 (dd, J = 8.6, 2.7 Hz, 1H), 7.77 - 7.67 (m, 2H), 7.30 - 7.19 (m, 2H); IR (thin film) 3219, 3069, 1651 cm1; ESIMS m / z 387 ([M + H]+).2-Chloro- / V-(4-cyanophenyl)-5-nitrobenzamide (C146)CIIsolated as a yellow solid (0.252 g, 30%): Ή NMR (400 MHz, DMSO-de) δ 11.15 (s, 1H), 8.55 (d, J = 2.7 Hz, 1H), 8.37 (dd, J = 8.8, 2.8 Hz, 1H), 7.98 - 7.80 (m, 5H); IR (thin film) 3275, 3100, 2222, 1667 cm1; ESIMS m / z 303 ([M + H]+).2-Chloro-5-nitro- / V-(4-(trif1uoromethyl)phenyl)benzamide (C147)XIIsolated as a yellow solid (0.316 g, 35%): Ή NMR (400 MHz, CDCb) δ 8.63 (d, J = 2.7 Hz, 1H), 8.30 (dd, J = 8.8, 2.7 Hz, 1H), 8.00 (s, 1H), 7.79 (d, J = 8.5 Hz, 2H), 7.72 - 7.63 (m, 3H); IR (thin film) 3255, 3078, 1663 cm1; ESIMS m / z 346 ([M + H]+). 2-Chloro-A-(4-chlorophenyl)-5-nitrobenzamide (C148)XIIsolated as a yellow solid (0.339 g, 42%): Ή NMR (400 MHz, CDCb) δ 8.62 (d, J = 2.7 Hz, 1H), 8.28 (dd, J = 8.8, 2.7 Hz, 1H), 7.84 (s, 1H), 7.67 (d, J = 8.8 Hz, 1H), 7.60 (d, J = 8.8 Hz, 2H), 7.38 (d, J = 8.8 Hz, 2H); IR (thin film) 3246, 3105, 1657 cm"1; ESIMS m / z 312 ([M + H]+).2-Chloro-A-(2-chloro-4-f1uorophenyl)-5-nltrobenzamide (C149)XIIsolated as a yellow solid (0.135 g, 13%): Ή NMR (400 MHz, CDCb) δ 8.70 (d, J = 2.7 Hz, 1H), 8.49 (dd, J = 9.2, 5.6 Hz, 1H), 8.37 (s, 1H), 8.31 (dd, J = 8.8, 2.7 Hz, 1H), 7.70 (d, J = 8.8 Hz, 1H), 7.22 (dd, J = 7.9, 2.9 Hz, 1H), 7.11 (ddd, J = 9.2, 7.9, 2.9 Hz, 1H); IR (thin film) 3237, 3104, 1660 cm"1; ESIMS m / z 330 ([M + H]+).2-Chloro-5-nitro-W-(o-tolyl)benzamide (C150)XIIsolated as a light red solid (0.221 g, 28%): >H NMR (400 MHz, CDCb) δ 8.68 (d, J = 2.7 Hz, 1H), 8.28 (dd, J = 8.8, 2.7 Hz, 1H), 7.94 (d, J = 8.0 Hz, 1H), 7.74 (s, 1H), 7.68 (d, J = 8.8 Hz, 1H), 7.33 - 7.26 (m, 2H), 7.18 (t, J = 7.0 Hz, 1H), 2.36 (s, 3H); IR (thin film) 3239, 3103, 1656 cm1; ESIMS m / z 290 ([M-H] ). / V-(4-Fluorophenyl)-2-methyl-5-nitrobenzamide (C151)Isolated as a light brown solid (0.504 g, 63%): Ή NMR (400 MHz, CDCh) δ 8.36 (s, 1H), 8.23 (d, J = 8.4 Hz, 1H), 7.67 - 7.56 (m, 2H), 7.53 (s, 1H), 7.47 (d, J = 8.5 Hz, 1H), 7.10 (t, J = 8.2 Hz, 2H), 2.62 (s, 3H); IR (thin film) 3264, 3074, 1648 cnr1; ESIMS m / z 275 ([M + H]+).2-Bromo- / V-(4-fluorophenyl)-5-nitrobenzamide (C152).BrIsolated as a light brown solid (0.370 g, 51%): Ή NMR (400 MHz, CDC ) δ 8.48 (d, J = 2.6 Hz, 1H), 8.17 (dd, J = 8.8, 2.7 Hz, 1H), 7.86 (d, J = 8.8 Hz, 1H), 7.66 (s, 1H), 7.64 - 7.56 (m, 2H), 7.15 - 7.06 (m, 2H); IR (thin film) 3241, 3097, 1657 cm'1; ESIMS m / z 340 ([M + H]+).A-(4-Fluorophenyl)-5-nitro-2-(lH-l,2,4-triazol-l-yl)benzamlde (C153)N■Isolated as a brown solid (0.367 g, 47%): Ή NMR (400 MHz, CDCb) δ 8.69 (d, J = 2.5 Hz, 1H), 8.59 (s, 1H), 8.49 (dd, J = 8.7, 2.6 Hz, 1H), 8.19 (s, 1H), 7.90 (s, 1H), 7.79 (d, J = 8.8 Hz, 1H), 7.50 - 7.42 (m, 2H), 7.10 - 7.03 (m, 2H); IR (thin film) 3135, 3013, 1673 cm"1; ESIMS m / z 328 ([M + H]+).v-(4-Fluorophenyl)-4-nitropicolinamide (C154)O.FIsolated as a yellow solid (0.602 g, 74%): Ή NMR (400 MHz, CDCb) δ 9.84 (s, 1H), 8.99 (dd, J = 2.2, 0.6 Hz, 1H), 8.94 (dd, J = 5.3, 0.6 Hz, 1H), 8.24 (dd, J = 5.3, 2.2 Hz, 1H), 7.80 - 7.70 (m, 2H), 7.16 - 7.07 (m, 2H); IR (thin film) 3309, 3076, 1680 cm1; ESIMS m / z 262 ([M + H]+).2-Chloro- / V-(4-fluorophenyl)-3-nitrobenzamide (C155)FIsolated as a yellow solid (0.544 g, 71%): Ή NMR (400 MHz, CDCb) δ 7.87 (ddd, J = 12.8, 7.9, 1.6 Hz, 2H), 7.65 (s, 1H), 7.62 - 7.57 (m, 2H), 7.54 (t, J = 7.9 Hz, 1H), 7.14 - 7.06 (m, 2H); IR (thin film) 3263, 3079, 1654 cm1; ESIMS m / z 296 ([M + H]+). A-(4-Fluorophenyl)-2-methoxy-5-nitrobenzamide (C156)CH3FIsolated as a light brown solid (0.624 g, 81%):!H NMR (400 MHz, CDCb) δ 9.46 (s, 1H), 9.15 (d, J = 2.9 Hz, 1H), 8.38 (dd, J = 9.1, 3.0 Hz, 1H), 7.66 - 7.58 (m, 2H), 7.16 (d, J = 9.1 Hz, 1H), 7.11 - 7.04 (m, 2H), 4.20 (s, 3H); IR (thin film) 3350, 2082, 1658 cm1; ESIMS m / z 291 ([M + H]+).2-Chloro-5-nitro-A-phenylbenzamide (C157)Isolated as a white solid (1.51 g, 73%): Ή NMR (400 MHz, CDCb) δ 8.61 (d, J =2.7 Hz, 1H), 8.26 (dd, J = 8.8, 2.7 Hz, 1H), 7.85 (s, 1H), 7.70 - 7.59 (m, 3H), 7.46 - 7.36 (m, 2H), 7.25 - 7.18 (m, 1H);13C NMR (101 MHz, CDCb) δ 162.10, 137.49, 136.87, 136.54, 131.63, 129.30, 126.00, 125.55, 125.37, 120.33, 99.98; ESIMS m / z 277 ([M + H]+).2-Chloro-N-(2-fluorophenyl)-5-nitrobenzamide (C158)Isolated as a white solid (1.38 g, 63%): Ή NMR (400 MHz, CDC ) δ 8.68 (d, J = 2.7 Hz, 1H), 8.50 - 8.40 (m, 1H), 8.29 (dd, J = 8.8, 2.8 Hz, 1H), 8.19 (s, 1H), 7.68 (d, J = 8.8 Hz, 1H), 7.26 - 7.20 (m, 1H), 7.20 - 7.12 (m, 2H);19F NMR (376 MHz, CDCb) δ - 130.45; ESIMS m / z 295 ([M + H]+).2-Chloro- / V-(2,4-dlf1uorophenyl)-5-nitrobenzamide (C159)XIIsolated as a light purple solid (1.48 g, 64%): Ή NMR (400 MHz, CDC ) δ 8.68 (d, J = 2.7 Hz, 1H), 8.40 (td, J = 9.1, 6.7 Hz, 1H), 8.30 (dd, J = 8.8, 2.7 Hz, 1H), 8.09 (s, 1H), 7.69 (d, J = 8.8 Hz, 1H), 7.04 - 6.89 (m, 2H);19F NMR (376 MHz, CDCb) δ - 113.04 (d, J = 5.0 Hz), -125.45 (d, J = 5.1 Hz); ESIMS m / z 313 ([M + H]+).2-Chloro- / V-(4-f1uorophenyl)- / V-methyl-5-nltrobenzamide (C160)XIIsolated as a green solid (1.80 g, 78%): Ή NMR (400 MHz, CDCb) δ 8.04 - 7.97 (m, 2H), 7.40 (dd, J = 8.5, 0.7 Hz, 1H), 7.19 - 7.11 (m, 2H), 6.96 - 6.88 (m, 2H), 3.50 (s, 3H);19F NMR (376 MHz, CDCb) δ -112.30; ESIMS m / z 309 ([M + H]+).2-Chloro- / V-(3-f1uorophenyl)-5-nitrobenzamide (C161)XIIsolated as a white solid (1.38 g, 63%): Ή NMR (400 MHz, CDCb) δ 8.62 (d, J = 2.8 Hz, 1H), 8.28 (dd, J = 8.8, 2.7 Hz, 1H), 7.90 (s, 1H), 7.67 (d, J = 8.8 Hz, 1H), 7.61 (dt, J = 10.5, 2.3 Hz, 1H), 7.36 (td, J = 8.2, 6.2 Hz, 1H), 7.30 - 7.27 (m, 1H), 6.93 (tdd, J = 8.2, 2.5, 1.0 Hz, 1H);19F NMR (376 MHz, CDCb) δ -110.61; ESIMS m / z 295 ([M + H]+).2-Chloro- / V-(3-cyanophenyl)-5-nitrobenzamide (C162)Isolated as a light solid (1.41 g, 63%): ESIMS m / z 302 ([M + H]+).2-Chloro-A / -(2,3-dif1uorophenyl)-5-nitrobenzamide (C163)XIIsolated as a white solid (1.24 g, 53%): Ή NMR (400 MHz, CDCh) δ 8.69 (d, J = 2.8 Hz, 1H), 8.31 (dd, J = 8.8, 2.7 Hz, 1H), 8.23 (t, J = 7.3 Hz, 2H), 7.70 (d, J = 8.8 Hz, 1H), 7.22 - 7.11 (m, 1H), 7.09 - 6.96 (m, 1H);I9F NMR (376 MHz, CDCh) δ -137.23 (d, J = 20.2 Hz), -154.19 (d, J = 20.3 Hz); ESIMS m / z 313 ([M + H]+).2-Chloro- / V-(3,4-dlf1uorophenyl)-5-nitrobenzamide (C164)XIIsolated as a dark colored solid (1.50 g, 65%): >H NMR (400 MHz, DMSO- e) δ 10.95 (s, 1H), 8.51 (d, J = 2.8 Hz, 1H), 8.36 (dd, J = 8.8, 2.8 Hz, 1H), 7.91 (d, J = 8.9 Hz, 1H), 7.89 - 7.83 (m, 1H), 7.54 - 7.37 (m, 2H);I9F NMR (376 MHz, DMSO-de) δ - 136.87 (d, J = 23.1 Hz), -143.43 (d, J = 23.0 Hz); ESIMS m / z 313 ([M + H]+).2-Chloro-5-nitro- / V-(2,4,6-trif1uorophenyl)benzamide (C165)XIIsolated as a white solid (1.80 g, 73%): Ή NMR (400 MHz, DMSO-de) δ 10.59 (s, 1H), 8.43 - 8.30 (m, 2H), 7.93 (d, J = 8.7 Hz, 1H), 7.44 - 7.30 (m, 2H);19F NMR (376 MHz, DMSO- / e) δ -108.89 (d, J = 5.8 Hz), -114.25 (d, J = 5.7 Hz); ESIMS m / z 331 ([M + H]+).2-Chloro-A / -(2,6-dif1uorophenyl)-5-nitrobenzamide (C166)CIFH0. N0"0FIsolated as a white solid (1.06 g, 46%): »H NMR (400 MHz, DMSO-de) δ 10.61 (s, 1H), 8.51 - 8.21 (m, 2H), 7.93 (d, 3 = 8.7 Hz, 1H), 7.60 - 7.36 (m, 1H), 7.25 (t, 3 = 8.2 Hz, 2H);19F NMR (376 MHz, DMSO-de) δ -117.43; ESIMS m / z 313 ([M + H]+).4-Chloro-A / -(4-fluorophenyl)-3-nitrobenzamide (C167)FIsolated as a yellow solid (0.679 g, 88%): Ή NMR (400 MHz, CDCb) δ 8.36 (d, 3 = 2.1 Hz, 1H), 8.04 (dd, 3 = 8.4, 2.1 Hz, 1H), 7.95 (s, 1H), 7.69 (d, 3 = 8.4 Hz, 1H), 7.62 - 7.54 (m, 2H), 7.13 - 7.04 (m, 2H); IR (thin film) 3342, 3075, 1651 cm1; ESIMS m / z 295 ([M + H]+).A / -(4-Fluorophenyl)-2-methoxy-3-nitrobenzamide (C168)Isolated as a yellow solid (0.600 g, 65%): Ή NMR (400 MHz, DMSO-de) δ 10.60 (s, 1H), 8.04 (dd, 3 = 8.1, 1.7 Hz, 1H), 7.85 (dd, 3 = 7.7, 1.7 Hz, 1H), 7.78 - 7.68 (m, 2H), 7.44 (t, 3 = 7.9 Hz, 1H), 7.23 (dt, J = 11.5, 8.9 Hz, 2H), 3.88 (s, 3H);13C NMR (101 MHz, DMSO-c / e) δ 163.36, 149.49, 143.90, 135.07, 133.51, 133.03, 126.15, 124.42, 121.53 (d, JCF = 7.8 Hz), 115.43 (d, JCF = 22.3 Hz), 99.49, 63.30; ESIMS m / z 291 ([M + H]+).2-Chloro-iV-(3-fluorophenyl)-V-methyl-5-nitrobenzamide (C169)Isolated as a yellow solid (1.46 g, 64%): »H NMR (400 MHz, CDCb) δ 8.02 (d, J = 8.3 Hz, 2H), 7.42 (d, J = 8.5 Hz, 1H), 7.19 (td, J = 8.7, 6.6 Hz, 1H), 6.96 - 6.86 (m, 3H), 3.52 (s, 3H);19F NMR (376 MHz, CDCb) δ -110.00; ESIMS m / z 309 ([M + H]+). 2-Chloro- / V-(2-fluorophenyl)- / V-methyl-5-nitrobenzamide (C170)Isolated as a light brown solid (0.61 g, 27%): Ή NMR (400 MHz, CDC ) δ 8.13 (dd, J = 2.7, 1.3 Hz, 1H), 7.99 (dd, J = 8.8, 2.7 Hz, 1H), 7.38 (d, J = 8.8 Hz, 1H), 7.25 - 7.15 (m, 2H), 7.05 - 6.97 (m, 2H), 3.48 (d, J = 0.5 Hz, 3H).2-Chloro-A-(4-cyano-2-methylphenyl)-5-nitrobenzamide (C171)XIIsolated as a white solid (1.14 g, 49%): Ή NMR (400 MHz, DMSO-de) δ 10.43 (s, 1H), 8.56 (d, J = 2.8 Hz, 1H), 8.35 (dd, J = 8.8, 2.8 Hz, 1H), 7.89 (dd, J = 14.0, 8.6 Hz, 2H), 7.79 (d, J = 1.9 Hz, 1H), 7.77 - 7.69 (m, 1H), 2.34 (s, 3H); 'X NMR (101 MHz, DMSO-de) δ 163.33, 146.15, 140.02, 137.41, 137.00, 134.26, 133.14, 131.25, 130.22, 125.78, 125.48, 124.03, 118.76, 107.91, 17.62; ESIMS m / z 316 ([M + H]+).2-Chloro-A / -(4-f1 uoro-2-methyl phenyl )-5-nitrobenzamide (C172)XIIsolated as a light purple solid (1.45 g, 63%): Ή NMR (400 MHz, DMSO-tfe) δ 10.20 (s, 1H), 8.50 (d, J = 2.8 Hz, 1H), 8.34 (dd, J = 8.8, 2.8 Hz, 1H), 7.90 (d, J = 8.9 Hz, 1H), 7.51 (dd, J = 8.8, 5.6 Hz, 1H), 7.16 (dd, J = 9.8, 3.0 Hz, 1H), 7.09 (td, J = 8.6, 3.0 Hz, 1H), 2.30 (s, 3H);19F NMR (376 MHz, CDC ) δ -116.56; ESIMS m / z 309([M + H]+).A / -(4-Fluorophenyl)-6-nitroplcolinamide (C173)Isolated as a light brown solid (0.511 g, 49%): mp 169-170 °C; Ή NMR (400 MHz, DMSO-d6) δ 10.62 (s, 1H), 8.68 - 8.29 (m, 3H), 7.92 - 7.80 (m, 2H), 7.29 - 7.15 (m, 2H); ESIMS m / z 262 ([M + H]+).N-(4-Fluorophenyl)-4-methyl-3-nltrobenzamide (C174)Isolated as an off-white solid (0.711 g, 89%): mp 136-138 °C; Ή NMR (400 MHz, DMSO-de) δ 10.52 (s, 1H), 8.57 (d, J = 1.8 Hz, 1H), 8.21 (dd, J = 8.0, 1.8 Hz, 1H), 7.83 - 7.74 (m, 2H), 7.69 (d, J = 8.1 Hz, 1H), 7.28 - 7.16 (m, 2H), 2.60 (s, 3H); ESIMS m / z 275 ([M + H]+). / V-(4-fluorophenyl)-5-nitro-2-(trifluoromethoxy)benzamide (C175)Isolated as a yellow solid (0.544 g, 75%): mp 175-177 °C; Ή NMR (400 MHz, CDCb) δ 8.97 (d, J = 2.9 Hz, 1H), 8.43 (dd, J = 9.0, 2.9 Hz, 1H), 8.24 (s, 1H), 7.63 - 7.57 (m, 2H), 7.57 - 7.52 (m, 1H), 7.15 - 7.07 (m, 2H); ESIMS m / z 345 ([M + H]+). 3-Chloro-iV-(4-fluorophenyl)-5-nitrobenzamide (C176)CIIsolated as a yellow solid (0.645 g, 84%): mp 209-210 °C; Ή NMR (400 MHz, DMSO-de) δ 10.68 (s, 1H), 8.74 - 8.68 (m, 1H), 8.51 (t, J = 2.0 Hz, 1H), 8.47 (t, J = Hz, 1H), 7.84 - 7.74 (m, 2H), 7.30 - 7.17 (m, 2H); ESIMS m / z 295 ([M-H]").2-Chloro- / V-(2-chlorophenyl)-5-nitrobenzamide (C177)XIIsolated as a yellow solid (1.14 g, 49%): »H NMR (400 MHz, CDC ) δ 8.69 (d, J = 2.7 Hz, 1H), 8.53 (dd, J = 8.2, 1.5 Hz, 1H), 8.48 (s, 1H), 8.30 (dd, J = 8.8, 2.7 Hz, 1H), 7.69 (d, J = 8.8 Hz, 1H), 7.45 (dd, J = 8.0, 1.5 Hz, 1H), 7.42 - 7.32 (m, 1H), 7.20 - 7.10 (m, 1H);13C NMR (101 MHz, CDCb) δ 161.91, 146.79, 137.41, 136.03, 133.91,131.81, 129.29, 127.97, 126.28, 125.87, 125.79, 123.41, 122.01; ESIMS m / z 311 ([M + H]+).2-Chloro-A-(2-isopropyl phenyl )-5-nitrobenzamide (C178)Isolated as a white solid (1.79 g, 75%): Ή NMR (400 MHz, DMSO-de) δ 10.21 (s,1H), 8.45 (d, J = 2.7 Hz, 1H), 8.34 (dd, J = 8.8, 2.8 Hz, 1H), 7.89 (d, J = 8.8 Hz, 1H), 7.41 (ddd, J = 19.3, 7.6, 1.7 Hz, 2H), 7.27 (dtd, J = 18.7, 7.3, 1.6 Hz, 2H), 3.34 - 3.24 (m, 1H), 1.19 (d, J = 6.9 Hz, 6H);13C NMR (101 MHz, DMSO-de) δ 163.78, 146.11, 143.95, 138.02, 136.97, 133.74, 131.29, 127.35, 127.05, 125.90, 125.71, 125.50, 123.70, 27.19, 23.25; ESIMS m / z 319 ([M + H]+).2-Chloro- / V-(2-ethyl-6-methylphenyl)-5-nitrobenzamlde (C179)Isolated as a white solid (1.31 g, 55%): Ή NMR (400 MHz, DMSO-de) δ 10.14 (s, 1H), 8.36 (dd, J = 8.8, 2.8 Hz, 1H), 8.31 (d, J = 2.7 Hz, 1H), 7.92 (d, J = 8.8 Hz, 1H), 7.24 - 7.13 (m, 3H), 2.66 (q, J = 7.5 Hz, 2H), 2.30 (s, 3H), 1.17 (t, J = 7.5 Hz, 3H);13C NMR (101 MHz, DMSO-de) δ 163.25, 146.11, 141.22, 137.80, 136.96, 135.68, 133.26, 131.56, 127.89, 127.40, 126.30, 125.65, 123.36, 24.41, 18.24, 14.77; ESIMS m / z 319 ([M + H]+).2-Chloro- / V-(3-chlorophenyl)-5-nitrobenzamide (C180)Isolated as an off-white solid (1.46 g, 63%): Ή NMR (400 MHz, DMSO-de) δ 10.90 (s, 1H), 8.51 (d, J = 2.7 Hz, 1H), 8.36 (dd, J = 8.8, 2.8 Hz, 1H), 7.99 - 7.84 (m, 2H), 7.57 (ddd, J = 8.2, 2.0, 1.0 Hz, 1H), 7.42 (t, J = 8.1 Hz, 1H), 7.22 (ddd, J = 8.0, 2.1, 1.0 Hz, 1H);13C NMR (101 MHz, DMSO-de) δ 162.99, 146.13, 139.85, 137.29, 137.02, 133.13, 131.36, 130.60, 125.88, 123.95, 123.93, 119.24, 118.19; ESIMS m / z 311 ([M + H]+).2-Chloro-A / -(2,4-dif1uorophenyl)-V-methyl-5-nitrobenzamide (C181)Isolated as a green solid (0.72 g, 36%) : Ή N R (300 MHz, CDC ) δ 8. 13 (dd, J = 2.7, 1.4 Hz, 1H), 8.03 (dd, J = 8.8, 2.7 Hz, 1H), 7.40 (dd, J = 8.8, 0.4 Hz, 1H), 7.24 (td, J = 8.9, 5.9 Hz, 1H ), 6.84 - 6.71 (m, 2H), 3.45 (d, J = 0.5 Hz, 3H) ; IR (thin film) 3074, 1654, 1527, 1607 cm1; ESIMS m / z 327 ([M + H]+).2-Chloro-N-(4-cyano-2-fluorophenyl )-5-nltrobenzamide (C182 ),CIIsolated as a tan solid (0.642 g, 41%) : *H N M R (400 MHz, DMSO-c / e) δ 11.01 (s, 1H), 8.53 (d, J = 2.8 Hz, 1H), 8.41 - 8.24 (m, 2H), 7.98 (dd, J = 10.8, 1.9 Hz, 1H), 7.89 (d, J = 8.8 Hz, 1H), 7.77 (ddd, J = 8.5, 1.9, 0.9 Hz, 1H) ;19F NM R (376 MHz, DMSO-de) δ - 121.17 ; ESIMS m / z 320 ( [M + H]+).Example 29: Preparation of 2-fluoro- / V-(4-fluorophenyl )-5-nitrobenzamide (C183), FA solution of 2-fluoro-5-nitrobenzoic acid ( 1.0 g, 5.40 mmol) in thionyl chloride (7.0 ml_, 96 mmol) was heated to reflux for 4 hours. The reaction was thenconcentrated. Dry toluene ( 1.0 mL) was added to the residue twice and concentrated to remove any residual thionyl chloride. The residue was then dissolved in drydichloromethane (20 mL) . Pyridine (0.87 mL, 11 mmol) was added. The solution was cooled in an ice-bath, and 4-fluoroaniline (0.60 g, 5.4 mmol) dissolved indichloromethane ( 5.0 mL) was added over 20 minutes. The reaction was stirred in the ice-bath for 45 minutes. The reaction was washed with hydrochloric acid ( 1 M) (2 x 20 mL) followed by saturated aqueous sodium bicarbonate (2 x 20 mL). The organic layer was poured through a phase separator and concentrated to provide the title compound as a white solid ( 1.2 g, 71%) : Ή N M R (400 MHz, CDCb) δ 9.07 (dd, J = 6.6, 3.0 Hz, 1H), 8.42 (ddd, J = 9.0, 4.3, 3.0 Hz, 1H ), 8.32 (d, J = 13.8 Hz, 1H), 7.68 - 7.59 (m,2H), 7.40 (dd, J = 10.7, 9.0 Hz, 1H), 7. 16 - 7.06 (m, 2H);19F NM R (376 MHz, CDCb) δ - 104.29, - 116.18 ; ESIMS m / z 279 ( [M + H]+).The following compounds were prepared in like manner to the procedure outlined in Example 29:2-Fluoro- V-(4-fluorophenyl )-3-nitrobenzamide (C 184)FIsolated as a white solid ( 1.22 g, 81%) : Ή NM R (400 MHz, CDCb) δ 8.44 (ddd, J = 8.3, 6.6, 1.9 Hz, 1H), 8.27 (s, 1H), 8.22 (ddd, J = 8.1, 7.3, 1.9 Hz, 1 H), 7.68 - 7.57 (m, 2H), 7.49 (td, J = 8.0, 1.0 Hz, 1H), 7.16 - 7.05 (m, 2H) ;19F NMR (376 MHz, CDCb) δ - 116.17, - 121.77; EIMS m / z 279 ( [M]+).Example 30: Preparation of 2-chloro-5-nltro- V-(pyridin-4-yl )benzamide (C185)CITo a solution of 2-chloro-5-nitrobenzoic acid (0.500 g, 2.48 mmol) indichloromethane (8.3 mL) was added oxalyl chloride (0.239 mL, 2.73 mmol) slowly, followed by / V, / V-dimethylformamide ( 1 drop). The reaction was stirred at room temperature for 2 hours. To the solution was added triethylamine (0.691 mL, 4.96 mmol) followed by pyridin-4-amine (0.467 g, 4.96 mmol) in dichloromethane ( 1 mL). The reaction was allowed to stir at room temperature for 16 hours. Purification by flash column chromatography using 0-100% ethyl acetate / hexanes as eluent provided the title compound as a tan solid (0.401 g, 58%) : ' H NMR (400 MHz, DMSO-de) δ 11.10 (s, 1H), 8.64 - 8.45 (m, 3H), 8.37 (dd, J = 8.9, 2.8 Hz, 1 H), 7.92 (d, J = 8.8 Hz, 1H), 7.73 - 7.61 (m, 2H) ;13C NMR ( 101 MHz, DMSO-de) δ 163.67, 150.56, 146.14, 145.04, 136.95, 131.40, 126.06, 124.00, 113.68 ; ESIMS m / z 278 ( [M + H ]+).The following compounds were prepared in like manner to the procedure outlined in Example 30:2-Chloro-5-nitro-A / -(pyridin-3-yl )benzamide (C186)CIIsolated as a white solid (0.480 g, 70%): Ή NMR (400 MHz, DMSO-de) δ 10.95 (s, 1H), 8.85 (dd, J = 2.6, 0.7 Hz, 1H), 8.54 (d, J = 2.8 Hz, 1H), 8.42 - 8.31 (m, 2H), 8.15 (ddd, J = 8.3, 2.6, 1.5 Hz, 1H), 7.92 (d, J = 8.8 Hz, 1H), 7.44 (ddd, J = 8.3, 4.7, 0.8 Hz, 1H);13C NMR (101 MHz, DMSO- / e) δ 163.19, 146.13, 145.14, 141.29, 137.17, 137.04, 135.17, 131.38, 126.78, 125.92, 123.99, 123.76; ESIMS m / z 278 ([M + H]+). 2-Chloro-A-(2-chloropyridin-3-yl)-5-nitrobenzamlde (C187)Isolated as a white solid (0.364 g, 47%): Ή NMR (400 MHz, DMSO-de) δ 10.67 (s, 1H), 8.53 (d, J = 2.8 Hz, 1H), 8.40 - 8.31 (m, 2H), 8.26 (ddt, J = 6.1, 4.5, 2.4 Hz, 1H), 7.91 (d, J = 8.9 Hz, 1H), 7.55 (dd, J = 7.9, 4.7 Hz, 1H);13C NMR (101 MHz, DMSO de) δ 146.77, 146.02, 144.78, 137.16, 136.84, 135.87, 131.34, 131.11, 125.95, 124.13 123.50; ESIMS m / z 312 ([M + H]+).2-Chloro-N-(6-chloropyridin-3-yl)-5-nitrobenzamlde (C188)Isolated as a white solid (0.639 g, 83%): Ή NMR (400 MHz, DMSO-de) δ 11.10(s, 1H), 8.71 (d, J = 2.7 Hz, 1H), 8.56 (d, J = 2.7 Hz, 1H), 8.37 (dd, J = 8.8, 2.8 Hz, 1H), 8.19 (dd, J = 8.7, 2.8 Hz, 1H), 7.92 (d, J = 8.8 Hz, 1H), 7.57 (d, J = 8.7 Hz, 1H);13C NMR (101 MHz, DMSO-de) δ 163.20, 146.12, 144.54, 140.93, 137.05, 136.85, 134.79, 131.43, 130.44, 126.08, 124.39, 124.07; ESIMS m / z 312 ([M + H]+).2-Chloro- / V-(6-cyanopvridin-3-vl)-5-nitrobenzamlde (C189)Isolated as a white foam (0.433 g, 58%): ESIMS m / z 303 ([M + H]+).2-Chloro-V-(5-fluoropyridin-2-yl)-5-nitrobenzamide (C190)CIH0. N N0FIsolated as a light yellow foam (0.094 g, 21%): »H NMR (300 MHz, Acetone-de) δ 10.29 (s, 1H), 8.56 (d, J = 2.7 Hz, 1H), 8.46 - 8.34 (m, 2H), 8.27 (d, J = 3.0 Hz, 1H), 7.91 - 7.81 (m, 1H), 7.82 - 7.70 (m, 1H); IR (thin film) 3112, 1688, 1610, 1576, 1522 cm1; ESIMS m / z 296 ([M + H]+).5-(2-Chloro-5-nitrobenzamido)- / V-methylpicolinamlde (C191)CI0Isolated as a light brown foam (0.330 g, 66%): Ή NMR (400 MHz, DMSO- / e) δ 11.16 (s, 1H), 8.90 (d, J = 2.4 Hz, 1H), 8.66 (q, J = 4.8 Hz, 1H), 8.58 (d, J = 2.8 Hz, 1H), 8.37 (dd, J = 8.9, 2.8 Hz, 1H), 8.30 (dd, J = 8.5, 2.4 Hz, 1H), 8.07 (d, J = 8.5 Hz, 1H), 7.92 (d, 3 = 8.8 Hz, 1H), 2.82 (d, J = 4.8 Hz, 3H);13C NMR (101 MHz, DMSO-de) δ 163.92, 163.34, 146.15, 145.63, 139.52, 137.32, 137.06, 136.89, 131.43, 127.28, 126.07, 124.09, 122.28, 25.90; ESIMS m / z 335 ([M + H]+).2-Chloro-5-nitro- / V-(pyrldin-4-yl)benzamlde (C192)Isolated as a tan solid (0.401 g, 58%):JH NMR (400 MHz, DMSO-de) δ 11.10 (s, 1H), 8.64 - 8.45 (m, 3H), 8.37 (dd, J = 8.9, 2.8 Hz, 1H), 7.92 (d, J = 8.8 Hz, 1H), 7.73 - 7.61 (m, 2H);13C NMR (101 MHz, DMSO-de) δ 163.67, 150.56, 146.14, 145.04, 136.95, 131.40, 126.06, 124.00, 113.68; ESIMS m / z 278 ([M + H]+).Example 31: Preparation of 2-fluoro-W-(4-fluorophenyl)-W-methyl-5- nitrobenzamide (C193)To a solution of 2 -fluoro-5-nitrobenzoic acid (0.500 g, 2.70 mmol) indichloromethane ( 10 mL) was added oxalyl chloride (0.355 ml_, 4.05 mmol) slowly, followed by / V, / V-dimethylformamide ( 1 drop). The reaction was stirred at room temperature for 90 minutes. The reaction mixture was concentrated, and the residue was dissolved in dichloromethane ( 15 mL). To the solution was added pyridine (0.437 mL, 5.40 mmol), and the solution was cooled to 0 °C. To the cool solution was added 4- fluoro-N -methylaniline (0.338 g, 2.70 mmol) dissolved in dichloromethane (5 mL) over 20 minutes. After 45 minutes the ice bath was removed, and the reaction was allowed to stir at room temperature for 16 hours. The reaction was diluted with dichloromethane and washed with hydrochloric acid ( 1 M ) (2 x 20 mL). The organic layer was poured through a phase separator and concentrated to provide the title compound as a white solid (0.804 g, 92%) : 'H NM R (300 MHz, CDCb) δ 8.23 (dd, J = 5.5, 2.8 Hz, 1H), 8.13 (ddd, J = 9.1 , 4.4, 2.8 Hz, 1H), 7.14 - 7.05 (m, 2H), 7.05 - 6.87 (m, 3H), 3.49 (s, 3H) ; IR (thin film) 3039, 1647, 1627, 1506 cm" 1; ESIMS m / z 293 ( [M + H]+).The following compounds were prepared in like manner to the procedure outlined in Example 31 :2-Fluoro- V-(3-fluorophenyl )-A -methyl-5-nitrobenzamide (C194)Isolated as a white solid (0.740 g, 94%) : Ή NM R (300 MHz, CDCb) δ 8.26 (s, 1H), 8.22 - 8.07 ( m, 1H), 7.27 - 7.13 (m, 1H), 7.03 (t, J = 8.6 Hz, 1H ), 6.99 - 6.73 (m, 3H), 3.51 (s, 3H); IR (thin film) 3080, 1659, 1629, 1587 cm1.2-Fluoro- V-(4-fluorophenyl )-A -methyl-3-nitrobenzamide (C195 )FIsolated as a yellow solid (0.675 g, 86%) : Ή N MR (300 MHz, CDCb) δ 7.93 (dddJ = 8.6, 7.1, 1.8 Hz, 1H), 7.56 (ddd, J = 7.4, 5.3, 1.8 Hz, 1 H), 7.19 (td, J = 8.0, 1.1 Hz, 1H), 7.08 (ddd, J = 8.8, 4.7, 1.2 Hz, 2H), 6.99 - 6.88 (m, 2H), 3.49 (s, 3H); IR (thin film) 3086, 1653, 1614, 1536 cm" 1; ESIMS m / z 293 ( [M + H]+).2-Chloro-4-f1uoro-A -(4-fluorophenyl )-5-nitrobenzamide (C196)Isolated as a yellow solid (0.532 g, 75%): Ή NMR (300 MHz, CDCb) δ 8.54 (d, J = 7.8 Hz, 1H), 7.85 (s, 1H), 7.66 - 7.54 (m, 2H), 7.48 (d, J = 9.9 Hz, 1H), 7.17 - 7.03 (m, 2H); IR (thin film) 3265, 3072, 1614, 1530 cm"1; ESIMS m / z 313 ([M + H]+).2,4-Difluoro-v-(4-fluorophenyl)-5-nitrobenzamide (C197)Isolated as a green solid (0.576 g, 79%):!H NMR (300 MHz, CDCb) δ 9.00 (t, J = 8.2 Hz, 1H), 8.23 (d, J = 13.4 Hz, 1H), 7.67 - 7.53 (m, 2H), 7.21 (dd, J = 10.9, 9.7 Hz, 1H), 7.15 - 7.06 (m, 2H); IR (thin film) 3080, 1687, 1614, 1590 cm"1; ESIMS m / z 297 ([M + H]+). / V-(2,4-DifJuorophenyl)-2-f1uoro-5-nitrobenzamlde (C198)-FIsolated as a grey solid (3.1 g, 97%): Ή NMR (400 MHz, CDCb) δ 9.08 (dd, J = 6.6, 3.0 Hz, 1H), 8.56 (d, J = 14.5 Hz, 1H), 8.42 (ddt, J = 14.1, 8.7, 5.0 Hz, 2H), 7.41 (dd, J = 10.6, 9.1 Hz, 1H), 6.95 (tdd, J = 11.1, 7.0, 3.2 Hz, 2H);19F NMR (376 MHz, CDCb) δ -104.13 , -113.26 (d, J = 5.0 Hz), -125.68 (d, J = 5.2 Hz); ESIMS m / z 297 ([M + H]+).2-Fluoro-A / -methyl-5-nitro-N-phenylbenzamlde (C199).FIsolated as a brown oil (1.45 g, 98%):!H NMR (400 MHz, CDCb) δ 8.21 (dd, J = 5.6, 2.8 Hz, 1H), 8.15 - 8.05 (m, 1H), 7.26 - 7.14 (m, 3H), 7.09 (d, J = 7.7 Hz, 2H), 6.98 (t, J = 8.6 Hz, 1H), 3.52 (s, 3H);19F NMR (376 MHz, CDCb) δ -102.19; ESIMS m / z 275 ([M + H]+).2-Fluoro- / V-methyl-3-nitro- / V-phenylbenzamide (C200)O.Isolated as a light brown solid (1.38 g, 93%): Ή NMR (400 MHz, CDCb) δ 7.94 - 7.85 (m, 1H), 7.55 (ddd, J = 7.5, 5.4, 1.8 Hz, 1H), 7.26 - 7.12 (m, 4H), 7.08 (d, J = 7.6 Hz, 2H), 3.51 (s, 3H);19F NMR (376 MHz, CDCb) δ -118.54; ESIMS m / z 275 ([M + H]+). A / -(4-Cyano-2-fluorophenyl)-2-fluoro-5-nitrobenzamide (C201)FIsolated as a light brown solid (1.1 g, 84%): *H NMR (400 MHz, DMSO-de) δ 10.89 (s, 1H), 8.59 (dd, J = 5.8, 2.9 Hz, 1H), 8.49 (ddd, J = 9.1, 4.3, 3.0 Hz, 1H), 8.24 (t, J = 8.1 Hz, 1H), 7.99 (dd, J = 10.8, 1.8 Hz, 1H), 7.77 (ddd, J = 8.4, 1.9, 0.9 Hz, 1H), 7.69 (t, J = 9.2 Hz, 1H);l9F NMR (376 MHz, DMSO- / e) δ -103.66, -120.88; ESIMS m / z 304 ([M + H]+).Example 32: Preparation of / V-(2,4-difluorophenyl)-2-fluoro-V-methyl-5- nitrobenzamide (C202)FTo a solution of / V-(2,4-difluorophenyl)-2-fluoro-5-nitrobenzamide (C198) (1.00 g, 3.38 mmol) in dry Λ / ,V-dimethylformamide (15 mL) cooled in an ice bath was added sodium hydride (60% oil immersion, 0.162 g, 4.05 mmol). The slurry was stirred for 30 minutes, and iodomethane (0.422 mL, 6.75 mmol) was added. The reaction was stirred for 2 hours. An additional amount of sodium hydride (0.0400 g) was added. An additional amount of iodomethane (0.100 mL) was added. The reaction was left to stir for 16 hours. The reaction was quenched by the slow addition of water (15 mL) and diluted with ethyl acetate (25 mL). The phases were cut, and the organic layer washed with 1 : 1 brine / water (3 x 20 mL). The organic layer was dried over magnesium sulfate, filtered, and concentrated to provide the title compound as a brown oil (1.05 g, quant): Ή NMR (400 MHz, CDC ) δ 8.32 - 8.24 (m, 1H), 8.15 (ddd, J = 9.1, 4.3, 2.8 Hz, 1H), 7.23 - 7.12 (m, 1H), 7.02 (dd, J = 9.1, 8.2 Hz, 1H), 6.85 - 6.71 (m, 2H), 3.44 (s, 3H);19F NMR (376 MHz, CDCb) δ -102.79 (d, J = 5.6 Hz), -107.11 (d, J = 8.2 Hz), -115.48 (dd, J = 8.3, 5.6 Hz); ESIMS m / z 311 ([M + H]+).The following compounds were prepared in like manner to the procedure outlined in Example 32 :2-Chloro-iV-ethyl-VV-(4-fluorophenyl)-5-nitrobenzamide (C203)FIsolated as a tan solid using iodoethane (0.225 g, quant): Ή NMR (400 MHz, CDCb) δ 8.02 - 7.94 (m, 2H), 7.42 - 7.35 (m, 1H), 7.18 - 7.11 (m, 2H), 6.98 - 6.86 (m, 2H), 3.97 (q, J = 7.2 Hz, 2H), 1.27 (t, J = 7.2 Hz, 4H);19F NMR (376 MHz, CDCb) δ - 112.13; ESIMS m / z 323 ([M + H]+).2-Chloro- / V-(4-fJuorophenyl)-5-nitro-v-(2,2,2-trifluoroethyl)benzamide (C204)FFIsolated as a white solid using 2,2,2-trifluoroethylmethanesulfonate (0.147 g, 58%): *H NMR (400 MHz, CDCb) δ 8.03 (dd, J = 8.7, 2.7 Hz, 1H), 8.00 (d, J = 2.5 Hz, 1H), 7.42 (dd, J = 8.8, 0.5 Hz, 1H), 7.25 - 7.19 (m, 2H), 6.99 - 6.91 (m, 2H), 4.55 (q, J = 8.6 Hz, 2H);19F NMR (376 MHz, CDCb) δ -68.62, -110.49; ESIMS m / z 377 ([M + H]+). 2-Chloro-A-(4-fluorophenyl)-5-nitro-A / -propylbenzamide (C205)Isolated as a tan solid using iodopropane (0.296 g, quant): Ή NMR (400 MHz, DMSO-de) δ 8.32 (d, J = 2.8 Hz, 1H), 8.05 (dd, J = 8.8, 2.8 Hz, 1H), 7.62 (d, J = 8.8 Hz, 1H), 7.42 - 7.34 (m, 2H), 7.15 - 7.06 (m, 2H), 3.81 (t, J = 7.4 Hz, 2H), 1.55 (h, J = 7.4 Hz, 2H), 0.93 (t, J = 7.4 Hz, 3H);19F NMR (376 MHz, DMSO-d6) δ -113.51; ESIMS m / z 337 ([M + H]+). / V-Allyl-2-chloro-v-(4-fluorophenyl)-5-nitrobenzamlde (C206)CHO.FIsolated as a white solid using 3-bromoprop-l-ene (0.269 g, 91%): Ή NMR (400 MHz, DMSO- / e) δ 8.40 (d, J = 2.8 Hz, 1H), 8.06 (dd, J = 8.9, 2.8 Hz, 1H), 7.62 (d, J = 8.9 Hz, 1H), 7.43 - 7.30 (m, 2H), 7.17 - 7.02 (m, 2H), 5.93 (ddt, J = 17.2, 10.2, 6.0 Hz, 1H), 5.31 - 5.11 (m, 2H), 4.47 (d, J = 6.0 Hz, 2H);I9F NMR (376 MHz, DMSO-c / e) δ - 113.49; ESIMS m / z 335 ([M + H]+).A-(4-Cyano-2-methyl phenyl )-2-fluoro-A-methyl-5-nitrobenzamlde (C207)Isolated as a tan solid (0.595 g, 94%): >H NMR (400 MHz, DMSO-de) δ 8.52 - 8.17 (m, 2H), 7.94 (d, J = 10.1 Hz, 1H), 7.84 - 7.60 (m, 2H), 7.44 (s, 1H), 3.36 (s, 3H)15F NMR (376 MHz, DMSO- / e) δ -104.90 , -118.40; ESIMS m / z 318 ([M + H]+).2-Chloro- / V-(4-cyano-2-fluorophenyl)-A / -methyl-5-nitrobenzamide (C208)Isolated as a white solid (0.826 g, 95%): ESIMS m / z 334 ([M + H]+).Example 33: Preparation of 5-nltro-2-(lH-l,2,4-triazol-l-yl)benzoic acid (C209)^XTo a solution of methyl 5-nitro-2-(lH-l,2,4-triazol-l-yl)benzoate (C210) (1.24 g, 5.00 mmol) in tetrahydrofuran (25 mL) and water (5.0 mL) was added lithium hydroxide (0.359 g, 15.0 mmol). The reaction was stirred at room temperature for 2.5 hours. The reaction was acidified with hydrochloric acid (1 N), and the reaction mixture was extracted with ethyl acetate. The combined organic layers were washed with brine,dried over magnesium sulfate, filtered, and concentrated to provide the title compound as a faint yellow solid ( 1.14 g, 93%) : >H N M R (400 MHz, DMSO-de) δ 13.83 (s, 1H), 9.11 (s, 1H), 8.63 - 8.50 (m, 2H ), 8.29 (s, 1H), 7.98 (d, J = 8.7 Hz, 1H) ; IR (thin film) 3169, 3097, 1713 cm1; ESIMS m / z 235 ( [M + H]+).Example 34: Preparation of methyl 5-nitro-2-( lH-l,2,4-triazol-l-yl )benzoate (C210)To a solution of methyl 2-chloro-5-nitrobenzoate (2.00 g, 9.28 mmol) in N,N- dimethylformamide ( 18.5 mL) was added lH-l ,2,4-triazole (0.673 g, 9.74 mmol). The reaction was stirred at 50 °C for 2 hours, at room temperature overnight, and heated at 80 °C for 2 hours. Water was added, and the mixture was extracted with diethyl ether. The combined organic layers were washed with brine (2x), dried over magnesium sulfate, filtered, and concentrated to provide the title compound as a faint yellow solid ( 1.25 g, 51%) : Ή N MR (400 MHz, DMSO-tfe) δ 9.21 (s, 1H), 8.62 - 8.57 (m, 2H), 8.31 (s, 1H), 8.09 - 8.03 (m, 1H), 3.75 (s, 3H) ; ESIMS m / z 249 ( [M + H]+).Example 35: Preparation of methyl 6-[bis(tert-butoxycarbonyl )amlno]-3- chloro-pyridine-2-carboxylate (C211 )3'CH^To a solution of methyl 6-amino-3-chloropicolinate (2.00 g, 10.7 mmol) in tert- butanol (21 mL) and acetone (6.0 mL) was added 4-dimethylaminopyridine (0.0200 g, 0.161 mmol) and di-tert-butyl dicarbonate (8.21 mL, 35.4 mmol) . The reaction was stirred at room temperature for 2 days. The reaction was diluted with ethyl acetate, washed with water, dried over magnesium sulfate, filtered, and concentrated .Purification by flash column chromatography using 0-100% ethyl acetate / hexanes as eluent provided the title compound as a white solid (2.45 g, 56%) : Ή N MR (400 MHz, CDC ) δ 7.81 (d, J = 8.6 Hz, 1H ), 7.40 (d, J = 8.6 Hz, 1H), 3.97 (s, 3H), 1.46 (s, 18H) ; IR (thin film) 2978, 1778, 1742 cm" 1; EIMS m / z 387 ( [M]+).The following molecules in Table 1 may be prepared according to the procedures disclosed above.Table PI : Structure and preparation method for prophetic moleculesNo. Structure Prep'13, 14, 15,PI18, 18CI CI13, 14, 15,P218, 1813, 14, 15,P318CI CI13, 14, 15,P418CI CI13, 14, 15,P518Prep* means prepare according to Example or SchemeThe following compounds were prepared in like manner to the procedure outlined in Example 2.frans-2,2-Dichloro-3-(4-methoxyphenyl )cyclopropane-l-carboxylic acid (C212)Isolated as white crystals (0.090 g, 27%):>H NMR (400 MHz, CDCIs) δ 11.33 (s, 1H), 7.22 - 7.15 (m, 2H), 6.94 - 6.86 (m, 2H), 3.82 (s, 3H), 3.44 (d, J = 8.3 Hz, 1H), 2.83 (d, J = 8.4 Hz, 1H);13C NMR (101 MHz, CDCIs) δ 172.23, 159.52, 129.77, 124.17, 114.00, 62.40, 55.31, 40.37, 36.97; ESIMS m / z 260 ([M-H] ).trans-3-(4-Bromo-3-chlorophenyl)-2,2-dichlorocvclopropane-l-carboxylic acid (C213)Isolated as a brown solid (0.186 g, 60%): Ή NMR (400 MHz, CDC ) δ 7.63 (d, J = 8.3 Hz, 1H), 7.40 - 7.32 (m, 1H), 7.04 (ddd, J = 8.3, 2.2, 0.7 Hz, 1H), 3.42 (d, J = 8.3 Hz, 1H), 2.86 (d, J = 8.3 Hz, 1H);13C NMR (101 MHz, CDCb) δ 171.39, 134.91, 133.89, 133.08, 130.54, 128.16, 122.61, 61.39, 39.70, 37.14; ESIMS m / z 342.8 ([M-H]').trans-3-(3-Bromo-4-chlorophenyl)-2,2-dichlorocvclopropane-l-carboxylic acid (C214)Isolated as a tan solid (0.7577 g, 71%): »H NMR (400 MHz, CDCb) δ 7.53 (d, J = J = 2.1 Hz, 1H), 7.47 (d, J = 8.3 Hz, 1H), 7.17 (dd, J = 8.3, 2.1 Hz, 1H), 3.44 (d, J = 8.3 Hz, 1H), 2.86 (d, J = 8.3 Hz, 1H);13C NMR (101 MHz, CDCb) δ 171.40, 134.73, 133.87, 132.39, 130.43, 128.70, 122.74, 61.50, 39.53, 37.14; ESIMS m / z 342.7 ([M-H]")·trans-3-(3-Bromo-5-chlorophenyl)-2,2-dichlorocyclopropane-l-carboxylic acid (C215)CIIsolated as a tan solid (0.9102 mg, 40%): Ή NMR (400 MHz, Acetone-de) δ 7.67 (d, J = 1.6 Hz, 1H), 7.63 (s, 1H), 7.57 (d, J = 1.8 Hz, 1H), 3.53 (d, J = 8.5 Hz, 1H), 3.38 (d, J = 8.5 Hz, 1H);13C NMR (101 MHz, Acetone-c / e) δ 166.92, 138.16, 135.69, 131.59, 131.55, 129.10, 123.23, 62.52, 39.41, 37.85; ESIMS m / z 342.7 ([M-H]-)]. trans-2, 2-Dichloro-3-(3-chloro-5-(dif1uoromethyl)phenyl)cvclopropane-l- carboxyMc acid (C216)Isolated as an off-white solid (2.6 g, 63%): 'H NMR (300 MHz, CDCb) missing COOH signal δ 7.49 (s, 1H), 7.38 (s, 1H), 7.30 (s, 1H), 6.63 (t, J = 56.0 Hz, 1H), 3.50 (d, J = 8.4 Hz, 1H), 2.91 (d, J = 8.0 Hz, 1H);19F NMR (282.2 MHz, CDC ) δ -112.04; ESIMS m / z 313 ([M-H] ).trans-2, 2-Dichloro-3-(4-chloro-3-(difluoromethyl)phenyl)cyclopropane-l- carboxylic acid (C217)Isolated as an off-white solid (6.2 g, 69%): 'H NMR (400 MHz, CDCb) δ 10.5 (br s, 1H), 7.55 (s, 1H), 7.46 (d, J = 8.0 Hz, 1H), 7.34 (d, J = 8.4 Hz, 1H), 6.95 (t, J = 54.8 Hz, 1H), 3.50 (d, J = 8.4 Hz, 1H), 2.91 (d, J = 8.4 Hz, 1H);19F NMR (376.2 MHz, CDCb) δ -115.52; ESIMS m / z 313 ([M-H] ).trans-2, 2-Dichloro-3-(3-(difluoromethy I )-5-fluorophenyl)cyclopropane-l- carboxylic acid (C218)FIsolated as an off-white solid (5 g, 38%): Ή NMR (400 MHz, CDCb) missing COOH signal δ 7.23 - 7.21 (m, 2H), 7.11 (d, J = 8.8 Hz, 1H), 6.64 (t, J = 55.6 Hz, 1H), 3.51 (d, J = 8.4 Hz, 1H), 2.91 (d, J = 8.0 Hz, 1H);19F NMR (376.2 MHz, CDCb) δ -110.37; ESIMS m / z 297.19 ([M-H]").trans-2,2-Dichloro-3-(3-(difluoromethyl)-4-f1uorophenyl)cvclopropane-l- carboxylic acid (C219)Isolated as an off-white solid (6.0 g, 77%): Ή NMR (400 MHz, CDCb) missing COOH signal δ 7.49 (d, J = 6.0 Hz, 1H), 7.40 (br s, 1H), 7.17 (t, J = 9.2 Hz, 1H), 6.90 (t, J = 54.8 Hz, 1H), 3.49 (d, J = 8.0 Hz, 1H), 2.89 (d, J = 8.4 Hz, 1H);19F NMR (376.2 MHz, CDCb) δ -114.47, -119.69; ESIMS m / z 297 ([M-H]").trans-2,2-Dichloro-3-(3-chloro-4-(dif1uoromethyl)phenyl)cyclopropane-l- carboxylic acid (C220)Isolated as an off-white solid (3.5 g, 42%): 'H NMR (400 MHz, CDCb) missing COOH signal δ 7.68 (d, J = 7.6 Hz, 1H), 7.35 (s, 1H), 7.29 (d, J = 8.4 Hz, 1H), 6.94 (t, J = 54.8 Hz, 1H), 3.48 (d, J = 8.4 Hz, 1H), 2.91 (d, J = 8.4 Hz, 1H);19F NMR (376.2 MHz, CDCb) δ -115.46; ESIMS m / z 313 ([M-H] ).trans-2,2-Dichloro-3-(4-(difluoromethyl)-3-fluorophenyl)cyclopropane-l- carboxylic acid (C221)FIsolated as an off-white solid (4.4 g, 77%): »H NMR (400 MHz, CDCb) δ 7.62 (t, J = 7.6 Hz, 1H), 7.18 (d, J = 7.6 Hz, 1H), 7.06 (d, J = 10.0 Hz, 1H), 6.89 (t, J = 54.8 Hz, 1H), 3.50 (d, J = 8.4 Hz, 1H), 2.90 (d, J = 8.4 Hz, 1H);19F NMR (376.2 MHz, CDCb) δ -114.42, -118.63; ESIMS m / z 297.15 ([M-H]-).trans-2, 2-Dichloro-3-(3-(difluoromethvl)phenyl)cvclopropane-l-carboxyllc acid (C222)Isolated as an off-white solid (6.2 g, 53%): Ή NMR (300 MHz, CDCb) δ 7.49 (br s, 2H), 7.41 (br s, 2H), 6.66 (t, J = 56.0 Hz, 1H), 3.53 (d, J = 8.4 Hz, 1H), 2.92 (d, J = 8.0 Hz, 1H);19F NMR (282.2 MHz, CDC ) δ -111.20 ; ESIMS m / z 279.20 ([M-H]"). trans-2, 2-Dichloro-3-(4-(difluoromethyl)phenyl)cyclopropane-l-carboxylic acid (C223)FIsolated as an off-white solid (7 g, 61%): Ή NMR (300 MHz, CDCb) δ 7.53 (d, J= 8.0 Hz, 2H), 7.37 (d, J = 8.0 Hz, 2H), 6.66 (t, J = 56.4 Hz, 1H), 3.52 (d, J = 8.4 Hz, 1H), 2.92 (d, J = 8.0 Hz, 1H);19F NMR (282.2 MHz, CDCb) δ -112.20; ESIMS m / z279.30 ([M-H]').trans-3-(4-Bromo-3,5-difluorophenyl)-2,2-dichlorocyclopropane-l-carboxylic acid (C224)CI CIIsolated as a white solid (2.13 g, 72%): mp 178.3-188.6 °C;!H NMR (400 MHz, CDCb) δ 6.90 (d, J = 7.1 Hz, 2H), 3.43 (d, J = 8.2 Hz, 1H), 2.86 (d, J = 8.2 Hz, 1H);19F NMR (376 MHz, CDCb) δ -103.87; ESIMS m / z 344.7 ([M-H] ).trans-3-(4-Bromo-3-f1uoro-5-methoxyphenyl)-2,2-dichlorocyclopropane-l- carboxylic acid (C225)CI CIH CIsolated as an oily solid (0.43 g, 37%): *H NMR (400 MHz, CDCb) δ 6.70 - 6. (m, 1H), 6.61 (d, J = 1.6 Hz, 1H), 3.95 (s, 3H), 3.44 (d, J = 8.3 Hz, 1H), 2.86 (d, J 8.3 Hz, 1H);15F NMR (376 MHz, CDCb) δ -104.22; ESIMS m / z 356.7 ([M-H] ).trans-3-(3-Bromo-5-f1uoro-4-methoxyphenyl)-2,2-dichlorocyclopropane-l- carboxylic acid (C226)CI CIIsolated as a brown oil (0.24 g, 65%): Ή NMR (400 MHz, CDCb) δ 7.24 (d, J = 7.9 Hz, 1H), 6.87 (d, J = 11.3 Hz, 1H), 3.91 (d, J = 3.8 Hz, 3H), 3.44 (d, J = 8.3 Hz, 1H), 2.80 (d, J = 8.3 Hz, 1H);19F NMR (376 MHz, CDCb) δ -135.11; ESIMS m / z 356.7 ([M-H]-).trans-2,2-Dichloro-3-(3,5-difluoro-4-methoxyphenyl)cyclopropane-l-carboxylic acid (C227)CI CIh CIsolated as a tan solid (0.440 g, 53%):!H NMR (400 MHz, CDCb) δ 10.72 (s, 1H), 6.89 - 6.77 (m, 2H), 4.02 (t, J = 1.2 Hz, 3H), 3.39 (d, J = 8.3 Hz, 1H), 2.80 (d, J = 8.3 Hz, 1H);19F NMR (376 MHz, CDCb) δ -127.43, -127.43, -127.44; ESIMS m / z 296 ([M-H]-).cls / trans-2, 2-Dlchloro-3-(3f4,5-trifJuorophenyl)cyclopropane-l-carboxyllc acid (C228)CI CIIsolated as a white solid (0.411 g, 53%): Ή NMR (400 MHz, CDCb) δ 7.72 (s, 1H), 7.06 - 6.74 (m, 2H), 3.46 - 3.23 (m, 1H), 3.01 - 2.74 (m, 1H);19F NMR (376 MHz, CDCb) δ -132.88, -132.94, -133.81, -133.87, -159.60, -159.65, -159.71, -160.34, -160.39, -160.45; ESIMS m / z 284 ([M-H] ).The following compounds were prepared in like manner to the procedure outlined in Example 3 :frans-2-Chloro-5-(2,2-dichloro-3-(4-methoxyphenyl)cyclopropyl)thiophene (C229)CI CI .CIoIcIsolated as a dark orange oil (0.455 g, 68%): Ή NMR (400 MHz, CDCb) δ 7.25 (d, J = 9.5 Hz, 2H), 6.92 (d, J = 8.8 Hz, 2H), 6.83 (d, J = 3.8 Hz, 1H), 6.80 (d, J = 3.5 Hz, 1H), 3.83 (s, 3H), 3.10 (s, 2H);13C NMR (101 MHz, CDCb) δ 159.40, 136.68, 129.87, 129.36, 126.30, 126.04, 125.59, 113.96, 65.28, 55.32, 41.23, 34.95.trans-2-((2,2-Dichloro-3-methyl-3-(4-(trifluoromethoxy)phenyl)cyclopropyl)methoxy)tetrahydro-2H-pyran (C230)CI CIIsolated as a pale yellow liquid (3.3 g, 77%) : Ή N MR (400 MHz, CDCh) δ 7.38 - 7.32 (m, 2H), 7.22 - 7.16 (d, J = 8.4 Hz, 2H ), 4.72 (dt, J = 17.0, 3.3 Hz, 1H), 4.13 (dd, J = 11.2, 6.6 Hz, 0.5H), 4.00 - 3.82 (m, 2H), 3.63 (dd, J = 11.3, 7.4 Hz, 0.5H), 3.60 - 3.52 (m, 1H), 2.20 (dt, J = 11.6, 4.5 Hz, 1H), 1.94 - 1.82 (m, 1H), 1.82 - 1.71 (m, 1H), 1.71 - 1.55 (m, 4H), 1.52 (d, J = 5.9 Hz, 3H) ;I9F NMR (376 MHz, CDCh) δ -57.85 ;I3C NMR ( 101 M Hz, CDCh) δ 148.26, 141.31, 130.14, 124.32, 121.77, 120.89, 119.21, 116.65, 99.17, 99.08, 67.92, 63.87, 63.77, 62.41, 37.91, 37.83, 36.92, 36.82, 30.74, 25.45, 19.93, 19.88, 19.48, 19.44; ESIMS m / z 441.4 (M + CH3CN) ; IR (thin film) 1257, 1222, 1208, 1163 cm htrans- l-Chloro-3-( 2,2-dichloro-3-(4-methoxyphenyl )cyclopropyl )-5- (difluoromethyl )benzene (C231)CIIsolated as a yellow liquid ( 11.5 g, 69%) : Ή N MR (300 MHz, CDCh) : δ 7.47 (s, 2H), 7.39 (s, 1H), 7.28 (d, J = 8.7 Hz, 2H), 6.93 (d, J = 8.7 Hz, 2H), 6.64 (t, J = 56.1 Hz, 1H), 3.83 (s, 3H), 3.16 (q, J = 8.7 Hz, 2H) .trans- l-Chloro-4-( 2, 2-dichloro-3-(4-methoxyphenyl )cyclopropyl )-2- (difluoromethyl ) benzene (C232)Isolated as a pale yellow solid ( 10.7 g, 83%) : » H NMR (400 MHz, CDCh) δ 7.65 (s, 1H), 7.46 - 7.41 (m, 2H), 7.28 (d, J = 8.4 Hz, 2H), 7.10 - 6.83 ( m, 3H), 3.83 (s, 3H), 3.18 - 3.13 ( m, 2H).trans-l-{2, 2-Dichloro-3-(4-methoxyphenyl )cyclopropyl )-3-(dif1uoromethyl )-5- fluorobenzene (C233)FIsolated as an off-white solid (16.5 g, 64%): 'H NMR (400 MHz, CDCb) δ 7.29 (d, J = 8.8 Hz, 2H), 7.20 (d, J = 8.8 Hz, 2H), 6.93 (d, J = 8.8 Hz, 2H), 6.65 (t, J = 56.0 Hz, 2H), 3.83 (s, 3H), 3.16 (s, 2H).trans-4-(2, 2-Dichloro-3-(4-methoxyphenvl)cyclopropyl)-2-(dlf1uoromethyl)-l- fluorobenzene (C234)Isolated as an off-white solid (10.0 g, 55%): ESIMS m / z 374 ([M + H]+).trans-2-Chloro-4-(2,2-dichloro-3-(4-methoxyphenyl)cyclopropyl)-l- (difluoromethyl)benzene (C235)FFIsolated as an off-white solid (10.0 g, 34%): »H NMR (400 MHz, CDCb) δ 7.68 (d, J = 8.0 Hz, 1H), 7.43 (s, 1H), 7.38 (d, J = 8.4 Hz, 1H), 7.28 - 7.25 (m, 2H), 7.09 - 6.92 (m, 3H), 3.83 (s, 3H), 3.15 (q, J = 12.0 Hz, 2H); ESIMS m / z 376 ([M + H]+).trans-2-Fluoro-4-(2,2-dichloro-3-(4-methoxyphenyl)cyclopropyl)-l- (dlfluoromethyl)benzene (C236)FFIsolated as a pale yellow liquid (6.9 g, 58%): Ή NMR (400 MHz, CDCb) δ 7.31 (t, J = 7.6 Hz, 1H), 7.27 (d, J = 9.2 Hz, 2H), 7.14 (d, J = 10.8 Hz, 1H), 7.04 - 6.76 (m, 4H), 3.83 (s, 3H), 3.16 (t, J = 8.8 Hz, 2H);19F NMR (376.2 MHz, CDCb) δ -114.14,-114.32, -119.30.trans- 1-( 2, 2-Dichloro-3-(4-methoxyphenyl)cyclopropyl)-3-(difluoromethyl)- benzene (C237)Isolated as a pale yellow solid (6.3 g, 95%): Ή NMR (400 MHz, CDCb) δ 7.50 (br s, 4H), 7.29 (d, J = 8.8 Hz, 2H), 6.93 (d, J = 8.0 Hz, 2H), 6.67 (t, 1H), 3.83 (s, 3H), 3.19 (s, 2H);19F NMR (376.2 MHz, CDCb) δ -110.87, -111.02.trans-\-{2, 2-Dichloro-3-(4-(difluoromethyl)phenyl)cyclopropyl)-4- methoxybenzene (C238)Isolated as a white solid (14 g, 69%): Ή NMR (400 MHz, CDCb) δ 7.54 (d, J = 8.0 Hz, 2H), 7.46 (d, J = 8.0 Hz, 2H), 7.28 (t, J = 8.4 Hz, 2H), 6.93 (d, J = 8.0 Hz, 2H), 6.67 (t, J = 56.8 Hz, 1H), 3.83 (s, 3H), 3.18 (s, 2H).The following compounds were prepared in like manner to the procedure outlined in Example 12.2-Chloro-5-((1R,3R)-2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)benzoic acid (C239)CIIsolated as a grey solid (3.80 g, 96%): Ή NMR (300 MHz, DMSO-de) δ 13.48 (s 1H), 10.90 (s, 1H), 8.15 (d, J = 2.6 Hz, 1H), 7.78 (dd, J = 8.8, 2.7 Hz, 1H), 7.63 (t, J 1.9 Hz, 1H), 7.57 - 7.50 (m, 3H), 3.62 (d, J = 8.5 Hz, 1H), 3.49 (d, J = 8.5 Hz, 1H); ESIMS m / z 454 ([M + H]+).2-Chloro-5-((1R,3R)-2,2-dlchloro-3-(3,4-dichlorophenyl)cyclopropane-l- carboxamldo)benzolc acid (C240)Isolated as a grey solid (3.70 g, 98%): »H NMR (300 MHz, DMSO-tfe) δ 13.47 (s, 1H), 10.95 (s, 1H), 8.16 (d, J = 2.7 Hz, 1H), 7.82 - 7.73 (m, 2H), 7.69 (d, J = 8.3 Hz, 1H), 7.53 (d, J = 8.7 Hz, 1H), 7.43 (dd, J = 8.5, 2.1 Hz, 1H), 3.60 (d, J = 8.5 Hz, 1H), 3.45 (d, J = 8.5 Hz, 1H); ESIMS m / z 454 ([M + H]+).2-Chloro-5-((l ?,3^)-2,2-dichloro-3-(3,4,5-trichlorophenyl)cyclopropane-l- carboxamido)benzoic acid (C241)CIIsolated as a grey solid (3.60 g, 99%): Ή NMR (400 MHz, DMSO-de) δ 13.44 (s, 1H), 10.91 (s, 1H), 8.16 (d, J = 2.7 Hz, 1H), 7.80 - 7.76 (m, 3H), 7.54 (d, J = 8.7 Hz, 1H), 3.63 (dt, J = 8.5, 0.7 Hz, 1H), 3.52 (d, J = 8.5 Hz, 1H); ESIMS m / z 488 ([M + H]+). 2-Chloro-5-((1R,3R)-2,2-dichloro-3-(3-chloro-4-fluorophenyl)cyclopropane-l- carboxamido)benzoic acid (C242)Isolated as a grey solid (3.80 g.99%): Ή NMR (400 MHz, DMSO-de) δ 13.48 (s,1H), 10.93 (s, 1H), 8.16 (d, J = 2.6 Hz, 1H), 7.78 (dd, J = 8.8, 2.7 Hz, 1H), 7.71 (dd, J = 7.2, 2.0 Hz, 1H), 7.53 (d, J = 8.7 Hz, 1H), 7.50 - 7.42 (m, 2H), 3.58 (d, J = 8.4 Hz, 1H), 3.42 (d, J = 8.5 Hz, 1H);19F NMR (376 MHz, DMSO-de) δ -117.29; ESIMS m / z 438 ([M + H]+).trans-2-Chloro-5-(2,2-dlchloro-3-(3,5-dichloro-4-methoxyphenyl)cyclo- propane-l-carboxamido)benzoic acid (C243)CIOHCIIsolated as a cream-colored solid ( 1.565 g, 90%) : mp 227-231 °C ; *H NM R (400 MHz, DMSO-de) δ 13.48 (s, 1H), 10.89 (s, 1H), 8.16 (d, J = 2.4 Hz, 1H), 7.78 (dd, J = 8.7, 2.4 Hz, 1H), 7.61 (s, 2H), 7.53 (d, J = 8.7 Hz, 1H), 3.84 (s, 3H), 3.57 (d, J = 8.4 Hz, 1H), 3.45 (d, J = 8.5 Hz, 1H) ;13C NMR ( 101 MHz, DMSO-de) δ 166.27, 162.66, 151.18, 137.58, 131.44, 131.42, 131.22, 129.72, 128.18, 125.90, 122.87, 121. 16, 62.19, 60.64, 38.51, 36.44; HRMS-ESI (m / z) [M + ]+calcd for C1SH 12CI 5NO4, 480.9209 ; found, 480.9216.trans-2-Chloro-5-( 2,2-dichloro-3-(3-chloro-4-fluorophenyl )cyclopropane-l- carboxamido)benzoic acid (C244)CIIsolated as a white solid (6.589 g, 93%) : 207-210 °C; Ή NM R (400 MHz, DMSO- de) δ 13.50 (s, 1H), 10.95 (s, 1H), 8.18 (d, J = 2.5 Hz, 1H), 7.80 (dd, J = 8.7, 2.5 Hz, 1H), 7.71 (d, J = 7.2 Hz, 1H), 7.51 (dd, J = 28.2, 8.8 Hz, 3H), 3.59 (d, J = 8.4 Hz, 1H), 3.43 (d, J = 8.5 Hz, 1H) ;13C NMR ( 101 MHz, DMSO-c / e) δ 166.22, 162.68, 158.01 , 155.55, 137.53, 131.37, 131.17, 131.00, 130.95, 130.91, 129.74, 129.67, 125.86, 122.82, 121.12, 119.49, 119.32, 116.91, 116.70, 62.21, 38.49, 36.58 ;19F NMR (376 MHz, DMSO- / e) δ - 117.26; ESIMS m / z 438 ( [M + H]+).trans-2,3-Dichloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamido)benzoic acid (C245)CICIIsolated as a tan solid ( 1.685 g, 79%) : mp 231-235 °C; Ή NM R (400 MHz, DMSO-de) 13.82 (s, 1 H), 11.05 (s, 1H), 8.13 (d, J = 2.4 Hz, 1 H), 7.97 (d, J = 2.4 Hz, 1H), 7.63 (s, 1H), 7.56 (s, 2H), 3.63 (d, J = 8.5 Hz, 1H), 3.50 (d, J = 8.5 Hz, 1H) ;13C NM R ( 101 MHz, DMSO-c / e) δ 165.84, 162.96, 138.00, 137.09, 134.14, 133.98, 133.01, 127.83, 127.64, 123.41 , 122.15, 119.27, 61.94, 38.37, 36.78; HRMS-ESI (m / z) [M + ]+calcd for C17H9CI6NO3, 484.8714; found, 484.8711.trans-2, 4-Dichloro-5-( 2, 2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamido)benzoic acid (C246)CIIsolated as a light-yellow solid (0.855 g, 42%) : mp 263-266 °C ; Ή NM R (500MHz, DMSO-c / e) δ 13.67 (s, 1H), 10.37 (s, 1H), 8.37 (s, 1H ), 7.85 (s, 1 H), 7.63 (s, 1H), 7.53 (d, J = 1.6 Hz, 2H), 3.82 (d, J = 8.6 Hz, 1H), 3.63 (d, J = 8.5 Hz, 1H) ;I3C N MR ( 126 MHz, DMSO-de) δ 165.41, 163.35, 137.17, 133.95, 133.66, 131.17, 129.96, 128.80, 128.24, 127.74, 127.60, 126.63, 62.37, 37.24, 37.09 ; HRMS-ESI (m / z) [M + ]+calcd for C17H9CI6NO3, 484.8714; found, 484.8715.The following compounds were prepared in like manner to the procedure outlined in Example 13 :trans-2-Chloro-5-( 2,2-dlbromo-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)- v-(2,6-difluorophenyl )benzamide (F 162)Isolated as an off-white solid (0.062 g, 44%)trans-tert-Bu y\ (4-(3-(2,2-dichloro-3-(3,4,5-trlchlorophenyl)cyclopropane-l- carboxamido)benzamido)-3-methylphenvl)carbamate (F262)CIIsolated as a yellow foam (0.043 g, 27%)trans-tert-Bu y\ (4-(3-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)benzamido)-3-methylphenyl)carbamate (F263)CIIsolated as a light yellow foam (0.043 g, 27.2%).trans-v-(4-(lH-Pyrazol-l-yl)phenyl)-2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropanecarboxamido)benzamide (F440)CIIsolated as a cream solid (0.310 g, 63%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropancarboxamldo)- / V-(4-(oxazol-2-yl)phenyl)benzamide (F446)CIIsolated as an off-white solid (0.203 g, 58.4%).trans-2-Chloro-5-(2,2-dlbromo-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)-v-(4-f1uorophenyl)-N-methylbenzamide (PF7)Br BrIsolated as a pale yellow glass (0.050 g, 29.6%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)- / V-(5-(trifluoromethyl)-lH-pyrazol-3-yl )benzamide (PF138)Isolated as an off-white solid (0.092 g, 45.1%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(2,4-dioxo-l,2,3,4-tetrahydropyrimldin-5-yl )benzamide (PF139)Isolated as a colorless glass (0.008 g, 6.37%) .trans-2-Chloro- / V-(4-chloropyridin-2-yl)-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF140)CI CI ^ - - -CIIsolated as a colorless glass (0.008 g, 6.37%) .trans-2-Chloro- / V-(6-chloropyridazin-3-yl)-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF148)CI CIIsolated as a dark red glass (0.0177 g, 14%) .trans-2-Chloro-5-( 2,2-dichloro-3-(3-chloro-5-fluorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )benzamlde (PF 1 )CIIsolated as a light yellow oil (0.076 g, 51%).trans-2-Chloro-5-( 2,2-dichloro-3-(3-chloro-5-fluorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )-A / -methylbenzamide (PF2)Isolated as a white foam (0.118 g, 77%).trans-2-Chloro-5-( 2,2-dichloro-3-(3-chloro-4-fluorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )benzamlde (PF4)CI CI / \ .CIIsolated as a white foam (0.094 g, 67%).trans-2-Chloro-5-( 2,2-dlchloro-3-(3-chloro-4-fluorophenyl )cyclopropane-l- carboxamldo)- v-(4-f1uorophenyl )-N-methylbenzamide (PF5)Isolated as a light yellow oil (0.097 g, 63%).trans-5-( 2, 2-Dichloro-3-(3,5-dichlorophenyl )cyclopropanecarboxamido)-2- ethyl- / V-(4-fluorophenyl )benzamide ( PF8)CIIsolated as a clear film (0.103 g, 54.9%).trans-5-{ 2, 2-Dichloro-3-( 3,5-dichlorophenyl )cyclopropanecarboxam ido)- / V-(4- fluorophenyl )-2-vinylbenzamide (PF9)Isolated as a faint yellow film (0.051 g, 20%) .trans-2-Chloro-5-( 2,2-dichloro-3-methyl-3-(4- (trifluoromethoxy)phenyl )cyclopropanecarboxamido)- V-(4- fluorophenyl )benzamide ( PF32)Isolated as a white solid (0.017 g, 42%).trans-2-Chloro-5-( 2,2-dlchloro-3-(4-chloro-3-fluorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )benzamlde (PF34)Isolated as a light yellow oil (0.134 g, 95%).trans-2-Chloro-5-(2,2-dlchloro-3-(4-chloro-3-fluorophenyl)cyclopropane-l- carboxamido)- / V-(4-fluorophenyl)-A / -methylbenzamide (PF35)Isolated as a white foam (0.101 g, 70%).trans-5-(3-(3-Bromo-5-chlorophenyl)-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro- / V-(4-f1uorophenyl)- / V-methylbenzamide (PF38)CIIsolated as a colorless oil (0.067 g, 64%).trans-A-(4-Acetamido-2-fluorophenyl)-2-chloro-5-(2,2-dichloro- dichlorophenyl)cyclopropane-l-carboxamido)benzamide (PF40)Isolated as a light yellow solid (0.043 g, 31%).trans-A-(4-Acetamido-2-fluorophenyl)-2-chloro-5-(2,2-dichloro-3-(3,4- dichlorophenyl)cyclopropane-l-carboxamido)benzamide (PF41)Isolated as a light brown solid (0.078 g, 55%) .trans- v-(4-Acetamido-2-fluorophenyl )-2-chloro-5-(2,2-dichloro-3-(3,4,5- trichlorophenyl )cvclopropane-l-carboxamido)benzamide ( PF42)CIIsolated as a white solid (0.085 g, 63%) .trans-2-Chloro-5-( 2,2-dlchloro-3-(3f4-dichlorophenyl )cyclopropane-l- carboxamido)- / V-(4-fluoro-2-methyl phenyl )benzamide (PF46)Isolated as a white solid (0.094 g, 75%).trans-2-Chloro-5-( 2,2-dichloro-3-(3-chloro-4-fluorophenyl )cyclopropane-l- carboxamido )-A -(4-fluoro-2-methyl phenyl )benzamide (PF48)Isolated as a white solid (0.077 g, 68%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(4-fluoro-2-methyl phenyl )- / V-methylbenzamide (PF49)Isolated as a white solid (0.084 g, 69%).trans-2-Chloro-5-(2,2-dlchloro-3-(3-chloro-4-fluorophenyl)cyclopropane-l carboxamido)- / V-(4-fluoro-2-methyl phenyl )- / V-methylbenzamide (PF50)Isolated as a light yellow glass (0.087 g, 73%).trans-2-Chloro-5-(2,2-dichloro-3-(4-methoxyphenyl)cyclopropane-l- carboxamido)-A-(4-fluorophenyl)benzamide (PF65)Isolated as a white solid (0.052 g, 35.3%).trans-2-Chloro-5-(2,2-dichloro-3-(4- isopropylphenyl)cyclopropanecarboxamido)-v-(4-f1uorophenyl)benzamide (PF66)CI CIHhCIsolated as a white solid (0.051 g, 31.8%).trans-2-Chloro-V-(2-cyano-4-fJuorophenyl)-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)benzamlde (PF67)Isolated as a white foam (0.114 g, 85%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-v-(2,3,4-trif1uorophenyl)benzamide (PF68)XIIsolated as a white solid (0.118 g, 87%).trans-2-Chloro- / V-(2-cyanophenyl)-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)benzamide (PF72)Isolated as a white solid (0.104 g, 80%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-A-(4-(trifluoromethyl)thiazol-2-yl)benzamide (PF134)CI CIIsolated as a white foam (0.096 g, 48%).trans-2-Chloro- / V-(5-chloropyridin-2-yl )-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF141)CIIsolated as a yellow foam (0.068 g, 43%).trans- v-(4-Acetamido-2-methylphenyl )-2-chloro-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF158)CH,Isolated as a white solid (0.051 g, 37%).trans-2-Chloro-5-( 2,2-dlchloro-3-(3-chloro-5-fluorophenyl )cyclopropane-l- carboxamldo)-W-(2,6-difluorophenyl )benzamide (F 160)XIIsolated as a white foam. (0.064 g, 41%).trans-2-Chloro-5-( 2,2-dichloro-3-(3-chloro-4-fluorophenyl )cyclopropane-l- carboxamldo)-W-(2,6-difluorophenyl )benzamide (F 161 )Isolated as a white foam (0.031 g, 20%).trans-2-Chloro-5-(2,2-dlchloro-3-(4-chloro-3-fluorophenyl)cyclopropane-l- carboxamido)- / V-(2,6-difluorophenyl)benzamide (F163)Isolated as a white foam (0.052 g, 36%).trans-5-(3-(3-Bromo-5-chlorophenyl)-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro- / V-(2,6-difluorophenyl)benzamide (F164)CIIsolated as a white solid (0.018 g, 17%).trans-2-Chloro-V-(2-cyano-4-fluorophenyl)-5-(2,2-dichloro-3-(3,4- dichlorophenyl)cyclopropane-l-carboxamido)benzamide (F190)Isolated as an orange foam (0.091 g, 80%).frans-2-Chloro-yv-(2-cyano-4-f1uorophenyl)-5-(2,2-dichloro-3-(3,4,5- trichlorophenyl)cyclopropane-l-carboxamldo)benzamide (F191)Isolated as a white solid (0.088 g, 73%).trans-2-Chloro- / V-(2-cyano-4-fluorophenyl)-5-(2,2-dichloro-3-(3-chloro-4- fluorophenyl)cyclopropane-l-carboxamido)benzamide (F192)NIsolated as an orange glass (0.076 g, 67%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(4-iodophenyl)benzamide (F193)Isolated as a white foam (0.121 g, 79%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(3-iodophenyl)benzamide (F194)Isolated as a light yellow solid (0.118 g, 77%).trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)cyclopropane-l- carboxamldo)-v-(2-f1uoro-4-lodophenyl)benzamlde (F203)Isolated as a white solid (0.133 g, 85%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(3-f1uoro-4-lodophenyl )benzamlde ( F204)Isolated as a white solid (0.116 g, 74%).trans-tert-Butyl-(4-(2-chloro-5-(2,2-dichloro-3-(3,4,5- trlchlorophenyl )cyclopropane-l-carboxamido)benzamidmethyl phenyl )(methyl )carbamate (F218)Isolated as a white solid (0.104 g, 71%).trans-tert-Butyl-(4-(2-chloro-5-(2,2-dichloro-3-(3-chloro-4- fluorophenyl )cyclopropane-l-carboxamido)benzamido)-3- methyl phenyl )(methyl )carbamate ( F219)Isolated as a white solid (0.107 g, 77%) .trans-tert-Butyl-(4-(2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)- V-methylbenzamido)-3- methyl phenyl )(methyl )carbamate ( F220)O CHiCH3Isolated as a white solid (0.127 g, 82%).trans-tert-Butyl-(4-(2-chloro-5-(( 1R,3R)-2,2-dichloro-3-(3,4,5- trlchlorophenyl )cyclopropane-l-carboxamido)-A -methylbenzamido)-3- methyl phenyl )(methyl )carbamate ( F221 )O CHH3Isolated as a white solid (0.101 g, 72%).trans-2-Chloro- / V-(2-cyano-4-fluorophenyl )-5-(2,2-dichloro-3-( 3,5- dichlorophenyl )cyclopropane-l-carboxamido)-A -methylbenzamide (F243)NCIIsolated as a white foam (0.084 g, 54%).trans-2-Chloro- / V-(2-cyano-4-fluorophenyl )-5-(2,2-dichloro-3-( 3,4,5- trlchlorophenyl )cyclopropane-l-carboxamido)-A -methylbenzamide (F244)NIsolated as a white foam (0.088 g, 56%).5-(trans-3-(4-Bromo-3-chlorophenyl )-2,2-dichlorocyclopropane-l- carboxamldo)-2-chloro-W-(4-fluorophenyl )benzamlde (F270)CIIsolated as a white foam (0.112 g, 78%).trans-3-{ 2, 2-Dichloro-3-( 3,5-dichlorophenyl )cyclopropane-l-carboxamido)-A / - (4-fluoro-2-methylphenyl )benzamide (F272)Isolated as a white foam (0.117 g, 84%).trans-3-{ 2, 2-Dichloro-3-( 3,5-dichlorophenyl )cyclopropane- l-carboxamido)-A / - (4-fluorophenyl )-A / -methylbenzamide (F273)Isolated as a white foam (0.123 g, 87%).trans-N-( 2-Chloro-4-fluorophenyl )-3-( 2, 2-dichloro-3-( 3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F274)Isolated as a white solid (0.076 g, 52%).5-(trans-3-(4-Bromo-3-chlorophenyl)-2,2-dichlorocyclopropane-l- carboxamldo)-2-chloro-W-(2,4-dlf1uorophenyl)benzamide (F306)XICIIsolated as an off-white solid (0.2825 g, 61%).5-(trans-3-(4-Bromo-3-chlorophenyl)-2,2-dichlorocyclopropane-l- carboxamldo)-2-chloro-W-(4-fluorophenyl)-A-methylbenzamide (F;Isolated as an off-white solid (0.3047 g, 62%).trans-5-(3-(3,5-d / s(Trifluoromethyl)phenyl)-2,2-dichlorocyclopropane' carboxamldo)-2-chloro-W-(2-cyano-4-f1uorophenyl)benzamide (F308)Isolated as a white solid (0.080 g, 58%).2-Chloro-5-((lf?,3f?)-2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-v-(3,5-difluoropyridin-2-yl)benzamide (F309)CI CI CI0 FHCINNH0FCIIsolated as a white solid (0.059 g, 39%).2-Chloro-5-((lf?,3f?)-2,2-dichloro-3-(3,4-dichlorophenyl)cyclopropane-l- carboxamldo)-W-(3,5-difluoropyridin-2-yl)benzamide (F310)Isolated as a white solid (0.062 g, 41%).2-Chloro-5-((1R,3R)-2,2-dichloro-3-(3f4,5-trichlorophenyl)cyclopropane-l- carboxamido)-v-(3,5-difluoropyridin-2-yl)benzamide (F311)CIIsolated as a white solid (0.054 g, 37%).2-Chloro-5-((1R,3R)-2,2-dichloro-3-(3-chloro-4-fluorophenyl)cyclopropane-l- carboxamido)- / V-(3,5-dlfluoropyridin-2-yl)benzamide (F316)Isolated as a white solid (0.071 g, 46%).5-(trans-3-(4-Bromo-3-chlorophenyl)-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro- / V-(2-cyano-4-fluorophenyl)benzamide (F320)NCIFBr" ^CIIsolated as a white foam (0. 1212 g, 42%).fert-Butyl (4-(5-(trans-3-(4-bromo-3-chlorophenyl )-2,2-dichlorocyclopropane- l-carboxamido)-2-chlorobenzamido)-3-methylphenyl )( methyl )carbamate (F321 )Isolated as a white solid (0.2009 g, 61%).tert-Butyl (4-(5-(trans-3-(4-bromo-3-chlorophenyl )-2f2-dichlorocyclopropane- l-carboxamido)-2-chlorobenzamido)-3-methylphenyl )carbamate (F322)CI.CH3CH3BrCIIsolated as a white foam (0.0812 g, 25%).5-(trans-3-(3-Bromo-4-chlorophenyl )-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro-N-(4-f1uorophenyl )benzamide (F330)Isolated as a pale yellow foam (0.1740 g, 64% ).5-(trans-3-(3-Bromo-4-chlorophenyl )-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro-A / -(2,4-dif1uorophenyl )benzamide (F331 )Isolated as a pale yellow foam (0.1959 g, 70%).5-(trans-3-(3-Bromo-4-chlorophenyl )-2,2-dlchlorocyclopropane-l- carboxamido)-2-chloro-A -( 2-cyano-4-fluorophenyl )benzamide ( F332)Isolated as a pale yellow foam (0.1893 g, 67%) .5-(trans-3-(3-Bromo-5-chlorophenyl )-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro- / V-( 2-cyano-4-f1uorophenyl )benzamide (F333)Isolated as a pale yellow foam (0.226 g, 77%).terf-Butyl (4-(5-( trans-3-(3-bromo-4-chlorophenyl )-2,2-dichlorocyclopropane- l-carboxamido)-2-chlorobenzamido)-3-methylphenyl )carbamate (F334)Isolated as a pale yellow foam (0.1789 g, 54% ).tert-Butyl (4-(5-( trans-3-(3-bromo-5-chlorophenyl )-2,2-dichlorocyclopropane- l-carboxamido)-2-chlorobenzamido)-3-methylphenyl )carbamate (F335)Isolated as a pale yellow foam (0.2256 g, 68%).trans-2-Chloro- / V-(2-cyano-4-fluorophenyl)-5-(2,2-dichloro-3-(3- (trifluoromethyl)phenyl)cyclopropane-l-carboxamldo)benzamide (F340)NIsolated as a white solid (0.106 g, 69%).trans-2-Chloro-5-(2,2-dlchloro-3-(3-chloro-5-cyanophenyl)cyclopropane-l- carboxamido)- / V-(3,5-difluoropyridin-2-yl)benzamide (F342)Isolated as a light yellow foam (0.061 g, 40%).trans-2-Chloro- / V-(2-cyano-4-fluorophenyl)-5-(2,2-dichloro-3-(3-chloro-5- cyanophenyl)cyclopropane-l-carboxamido)benzamide (F343)Isolated as a white solid (0.082 g, 53%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl)-A / -(prop-2-yn-l-yl)benzamide (F413)CIIsolated as a white foam (0.117 g, 75%).2-Chloro-5-((lf?,3f?)-2,2-dichloro-3-(3-chloro-4-fluorophenyl)cyclopropane-l- carboxamldo)-W-(2,4-difluorophenyl)-A-(prop-2-yn-l-yl)benzamlde (F414)Isolated as a light yellow foam (0.131 g, 79%).trans-2-Chloro-5-(2,2-dlchloro-3-(4-nltrophenyl)cyclopropane-l- carboxamldo)- / V-(4-f1uorophenyl)benzamlde (F422)Isolated as a yellow foam (0.1341 g, 54%).tert-Butyl- / V-((tert-butoxy)carbonyl)- / V-(3-(2-chloro-5-((l / ?,3 / ?)-2,2-dichloro-3- (3,5-dichlorophenyl)cyclopropane-l-carboxamldo)benzamido)-2,6- difluorophenyl)carbamate (F499)Isolated as a white solid (0.207 g, 80%).tert-Butyl- / V-((teri-butoxy)carbonyl)- / V-(3-(2-chloro-5-((1R,3R)-2,2-dichl (3,4-dichlorophenyl)cyclopropane-l-carboxamido)benzamido)-2,6- difluorophenyl)carbamate (F500)Isolated as a white solid (0.174 g, 67%).tert-Butyl- / V-((teri-butoxv)carbonyl)- / V-(3-(2-chloro-5-((l / ?,3R)-2,2-dichl (3,4,5-trichlorophenvl)cyclopropane-l-carboxamido)benzamido)-2,6- difluorophenyl)carbamate (F501)Isolated as a white solid (0.171 g, 64%).tert-Butyl-v-((tert-butoxy)carbonyl)- / V-(3-(2-chloro-5-((l / ?,3 / ?)-2,2-dichl (3-chloro-4-f1uorophenyl)cyclopropane-l-carboxamido)benzamido)-2,6- difluorophenyl)carbamate (F503)Isolated as a white solid (0.161 g, 75%).tert-Butyl-v-((tert-butoxy)carbonyl)-v-(3-(5-(3-(4-bromo-3-chlorophenyl)- 2,2-dichlorocyclopropane-l-carboxamido)-2-chlorobenzamido)-2,6- difluorophenyl)carbamate (F512)Isolated as a white foam (0.2060 g, 55%).tert-Butyl- V-((tert-butoxv)carbonyl )- V-(3-(5-(3-(3-bromo-4-chlorophenyl )- 2,2-dichlorocyclopropane-l-carboxamido)-2-chlorobenzamido)-2,6- dif1uorophenyl )carbamate (F513)Isolated as a pale yellow solid (0.2054 g, 54%).tert-Butyl- V-((tert-butoxy)carbonyl )- / V-(3-(5-(3-(3-bromo-5-chlorophenyl )- 2,2-dlchlorocyclopropane-l-carboxamido)-2-chlorobenzamido)-2,6- dif1uorophenyl )carbamate (F514)Isolated as a pale yellow foam (0.3134 g, 83%).trans-tert-Butyl- / V-((tert-butoxy)carbonyl )-W-(3-( 2-chloro-5-(2,2-dlchloro-3- (3-chloro-5-cyanophenyl )cyclopropane-l-carboxamldo)benzamido)-2,6- difluorophenyl )carbamate (F515)Isolated as a white solid (0.133 g, 63%).trans-teri-Butvl- / V-((tert-butoxy)carbonyl)- / V-(3-(2-chloro-5-(2,2-dlchloro- (3-(trifluoromethyl)phenyl)cvclopropane-l-carboxamldo)benzamido)-2,6- dif1uorophenyl)carbamate (F516)Isolated as a white solid (0.187 g, 90%).5-(trans-3-(3-Bromo-5-chlorophenyl)-2,2-dlchlorocyclopropane-l- carboxamido)-2-chloro-A-(4-f1uorophenyl)benzamide (PF37)CIIsolated as a pale yellow foam (0.2287 g, 84%).5-(trans-3-(3-Bromo-5-chlorophenyl)-2,2-dlchlorocyclopropane-l- carboxamido)-2-chloro-A-(2,4-dif1uorophenyl)benzamide (PF39)XIIsolated as a pale yellow foam (0.2352 g, 84%).trans-tert-Butyl (4-(2-chloro-5-(2,2-dlchloro-3-(3,4,5- trlchlorophenyl )cyclopropane-l-carboxamido)benzamido)-3- methyl phenyl )carbamate (F606)O H3CIsolated as a white solid (0.068 g, 47%) .trans-tert-Butyl (4-(2-chloro-5-(2,2-dlchloro-3-(3-chloro-4- fIuorophenyl )cyclopropane-l-carboxamido)benzamido)-3- methyl phenyl )carbamate (F607)HIsolated as a white solid (0.069 g, 51%).5-(trans-3-(4-bromo-3,5-dif1uorophenyl )-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro-A / -(4-f1uorophenyl )benzamide (F538)XIIsolated as a yellow foam (0.1445 g, 40%).5-(trans-3-(4-Bromo-3-f1uoro-5-methoxyphenyl )-2,2-dichlorocyclopropane-l- carboxamido)-2-chloro-A / -(4-f1uorophenyl )benzamide (F539)Isolated as a yellow foam (0.0322 g, 23%).5-(trans-3-(3-Bromo-5-f1uoro-4-methoxyphenyl )-2,2-dichlorocyclopropane-l-20 carboxamido)-2-chloro-A / -(4-f1uorophenyl )benzamide (F540)Isolated as a yellow foam (0.0243 g, 17%).5-(trans-3-(4-Bromo-3,5-difluorophenyl )-2,2-dichlorocyclopropane- l- carboxamldo)-2-chloro-W-(2,4-dlf1uorophenyl )benzamide (F541 )Isolated as a yellow foam (0.1307 g, 88%).5-(trans-3-(4-Bromo-3-fluoro-5-methoxyphenyl )-2,2-dichlorocyclopropane-l- carboxamldo)-2-chloro-W-(2,4-dlf1uorophenyl )benzamide (F542)Isolated as a yellow foam (0.0273 g, 19%).5-(( 1R,3f?)-3-(3-Bromo-4-chlorophenyl )-2,2-dichlorocyclopropane-l- carboxamldo)-2-chloro-W-(2,4-dlf1uorophenyl )benzamide (F572)Isolated as a yellow foam (0.0886 g, 68%).5-(( lS,3S)-3-(3-Bromo-4-chlorophenyl)-2,2-dlchlorocyclopropane-l- carboxamido)-2-chloro-A-(2,4-dif1uorophenyl)benzamide (F573)Isolated as a yellow foam (0.0833 g, 64%).tert-Butyl-v-((tert-butoxy)carbonyl)- / V-(3-(5-((1R,3R)-3-(3-bromo-4- chlorophenyl)-2,2-dichlorocyclopropane-l-carboxamido)-2-chlorobenzamido)- 2,6-dlf1uorophenyl)carbamate (F616)Isolated as a white foam (0.1054 g, 60%).tert-Butyl-v-((tert-butoxy)carbonyl)- / V-(5-(5-((1R,3R)-3-(3-bromo-4- chlorophenyl)-2,2-dichlorocyclopropane-l-carboxamido)-2-chlorobenzamldo)- 2,4-dlf1uorophenyl)carbamate (F617)Isolated as a yellow foam (0.0506 g, 29%).5-(trans)-2-Bromo-2-chloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-2-chloro-A-(4-f1uorophenyl)benzamide (PF33)CIIsolated as a white solid (0.069 mg, 48%).5-(trans)-2-Bromo-3-(3,5-dichlorophenyl )-2-f1uorocyclopropane-l- carboxamldo)-2-chloro-W-(4-fluorophenyl )benzamlde (PF51)CIIsolated as a pale yellow solid (0.095 g, 53%) .2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-N-(3,4,5-trlchlorophenyl )benzamide (PF 119)CI CIIsolated as a white solid (0.031 g, 22%).2-Chloro-5-(trans)-2-chloro-3-(3,5-dichlorophenyl )-2-f1uorocyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )benzamlde (PF 153)CIIsolated as a white foam (0.152 g, 73%).2-Chloro-5-(trans)-2,2-dichloro-3-(3-chloro-5-cyanophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )benzamlde (PF 155)CI CIIsolated as a white solid (0.104 g, 55%).The following compounds were prepared in like manner to the procedure outlined in Example 14 :trans-2-Chloro-5-(2,2-dlchloro-3-(3f5-dichlorophenyl)-v-methylcyclopropane- l-carboxamido)-v-(4-f1uorophenyl)benzamide (F183)Isolated as a brown waxy solid (0.033 g, 23%).trans-2-Chloro-5-(2,2-dlchloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)-v-(4-f1uoro-3-(trifluoromethyl)phenyl)benzamide (PF70)cl clo-F"FOIsolated as a light brown foam (0.111 g, 29.2%).trans-2-Chloro-5-(2,2-dlchloro-3-(3,5-dichlorophenyl)cyclopropane-l carboxamldo)-v-(3-(trifluoromethyl)phenyl)benzamide (PF71)cl clO ^r^a-FFOClIsolated as a light brown foam (0.147 g, 26.8%)trans-2-Chloro- / V-(4-chloro-3-methylphenyl)-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)benzamlde (PF113)CIIsolated as a white foam (0.091 g, 70.1%) .2-Chloro-A / -(4-chloro-3-methoxyphenyl )-5-(trans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF114)Isolated as a white foam (0.095 g, 71.2%) . / V-(4-Bromo-3-f1uorophenyl )-2-chloro-5-(trans)-2f2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF115)CIIsolated as a white foam (0.059 g, 41.9%) .2-Chloro- / V-(4-chloro-2-f1uorophenyl )-5-(trans)-2,2-dlchloro-3-(3f5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF116)Isolated as a white foam (0.091 g, 69.6%) .2-Chloro-5-(frans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)- / V-(3,4-dichlorophenyl )benzamide (PF117)Isolated as a white foam (0.030 g, 22%).2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(2,5-difluorophenyl )benzamide (PF118)CI FIsolated as a white foam (0.040 g, 31.5%) .2-Chloro- V-(3-chloro-4-cyanophenyl )-5-( trans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF120)CI CIIsolated as a white foam (0.020 g, 15%).2-Chloro- V-(3-chloro-4-f1uorophenyl )-5-(irans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF122)CIIsolated as a gold foam (0.093 g, 71.2%).2-Chloro- V-(4-chloro-3-f1uorophenyl )-5-(irans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF123)Isolated as a white foam (0.084 g, 64.3%) .2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(3-ethynylphenyl )benzamide (PF124)CIIsolated as a yellow foam (0.084 g, 56.2%).2-Chloro-A / -(3-chloro-4-methylphenyl )-5-(trans)-2,2-dichloro-3-(3, dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF125)Isolated as a white foam (0.107 g, 68.6%) .2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)- / V-( lH-lndol-6-yl )benzamide (PF126)Isolated as a white solid (0.055 g, 35.9%).2-Chloro- V-(3,4-dichloro-2-fluorophenyl )-5-(trans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (PF127)Isolated as a white foam (0.016 g, 9.62%).2-Chloro-5-((lf?,3f?)-2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl)benzamlde (F165)Isolated as a white foam (0.0242 g, 52.1%).2-Chloro-5-((lS,3S)-2,2-dichloro-3-(3,5-dlchlorophenyl)cycloprop carboxamldo)- / V-(4-f1uorophenyl)benzamlde (F166)Isolated as a white foam (0.221 g, 48.5%).2-Chloro-5-((1R,3R)-2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-A-(4-fluorophenyl)-A / -methylbenzamide (F169)Isolated as a white foam (0.095 g, 52.9%).2-Chloro-5-((lS,3S)-2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-v-(4-fluorophenyl)- / V-methylbenzamide (F170)CI CIIsolated as a white foam (0.103 g, 57.3%).2-Chloro-5-((1R,3R)-2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)- / V-(2,4-dlfluorophenyl)benzamide (F185)Isolated as a white foam (0.200 g, 52.1%).3-(trans)-2,2-Dichloro-3-(3,5-dichlorophenyl)cyclopropane-l-carboxamido)-v- (2,4-difluorophenyl)benzamide (F186)Isolated as a white foam (0.184 g, 68%).2-Chloro-5-((IS,3S)-2,2-dichloro-3-(3,4-dlchlorophenyl)cyclopropcarboxamldo)- / V-(4-f1uorophenyl)benzamlde (F208)Isolated as a white foam (0.090 g, 34.9%).2-Chloro-5-((1R,3R)-2,2-dichloro-3-(3,4-dichlorophenyl)cyclopropane-l- carboxamido)-A-(4-fluorophenyl)benzamide (F209)Isolated as a white foam (0.086 g, 33.4%).2-Chloro-5-((lS,3S)-2,2-dichloro-3-(3,4-dlchlorophenyl)cycloprop carboxamido)- / V-(2,4-difluorophenyl)benzamide (F210)XICI"Isolated as a white foam (0.096 g, 36.1%).2-Chloro-5-((1R,3R)-2,2-dichloro-3-(3,4-dichlorophenyl)cyclopropane-l- carboxamido)-A-(2,4-difluorophenyl)benzamide (F211),CIIsolated as a white foam (0.076 g, 28.6%).2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dlchlorophenyl)cyclopropane-l- carboxamido)-A-(2-methylisolndolin-5-yl)benzamlde (F498)CI CI ^ |N-CH,Isolated as a tan foam (0.073 g, 53.9%).2-Chloro-5-(2,2-dichloro-3-c / s-(3,5-dichlorophenyl)cyclopropane-l- carboxamido)-A / -(4-fluorophenyl)benzamide (F629)CI CI FCICIIsolated as an off-white solid (0.027 g, 29%) .The following compounds were prepared in like manner to the procedure outlined in Example 15:trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamido)- / V-(4-fluoro-3-methoxyphenyl )benzamide (PF52)Isolated as a white foam (0.080 g, 78%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamido)-A -(4-fluoro-3,5-dimethylphenyl )benzamide (PF53)Isolated as a white solid (0.056 g, 55%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamido)-A -(4-fluoro-2,3-dimethylphenyl )benzamide (PF54)CICH3CIFCIIsolated as a white solid (0.064 g, 63%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamido)-A -(2,4-difluoro-3-methylphenyl )benzamide (PF55)CICH3CIFCIIsolated as a white solid (0.038 g, 37%).trans-2-Chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uoro-2-methoxyphenyl )benzamide (PF58)CI H3CCIFCIIsolated as a white solid (0.048 g, 47%).trans-methyl (4-( 2-chloro-5-( 2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane- l-carboxamido)benzamido)phenyl )carbamate (PF 110)CIIsolated as a white foam (0.096 g, 72%).trans-2-Chloro-5-(2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(thiophen-3-yl )benzamide (PF152)CIIsolated as an off-white glass (0.096 g, 81%) .trans-tert-Butyl-(4-(2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlmethyl phenyl )carbamate (F 197)Isolated as a white solid (0.056 g, 55%).trans-tert-Butyl-(4-(2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamldo)-3- methyl phenyl )(methyl )carbamate ( F198)Isolated as a white solid (0.169 g, 44%).trans- / V-(Benzo[ ?]thiophen-5-yl )-2-chloro-5-( 2,2-dlchloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F452)IIsolated as an off-white foam (0.125 g, 81%) .trans- / V-(Benzo[d]thiazol-5-yl )-2-chloro-5-( 2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F482)Isolated as a white powder (0.092 g, 59%) .trans-tert-Butyl (4-(2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamldo)-3- fluorophenyl ) (methyl )carbamate (F600)o CHIsolated as a white solid (0.066 g, 22%).trans-tert-Butyl-V-((tert-butoxy)carbonyl)-A / -(4-(2-chloro-5-(2,2-dichl (3,5-dichlorophenyl)cyclopropane-l-carboxamldo)benzamido)-2- fluorophenyl)carbamate (F601)CHCH3CH3Isolated as a white foam (0.093 g, 55%).trans-tert-Butyl- / V-((tert-butoxy)carbonyl)- / V-(4-(2-chloro-5-(2,2-dlchl (3,5-dlchlorophenyl)cyclopropane-l-carboxamido)benzamido)-3- fluorophenyl)carbamate (F602)CHIsolated as a white foam (0.029 g, 17%).trans-tert- ut \ (4-(2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)benzamido)-2- fluorophenyl)(methyl)carbamate (F603)Isolated as a white foam (0.090 g, 60.3%)trans-tert-Butyl (3-(2-chloro-5-(2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamldo)phenyl )carbamate (F604)Isolated as a colorless glass (0.091 g, 68%) .trans-tert-Butyl (3-(2-chloro-5-(2,2-dlchloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamldo)phenyl )(methyl ) carbamate (F605)Isolated as a colorless glass (0.074 g, 54%) .trans-tert-Butyl (5-(2-chloro-5-(2,2-dlchloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlmethoxyphenyl )carbamate (F608)CIIsolated as a pink solid (0.121 g, 87%) .trans-tert-Butyl (5-(2-chloro-5-(2,2-dlchloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlmethoxy phenyl )(methyl )carbamate ( F609)CIIsolated as an orange solid (0.122 g, 86%).trans-2-Chloro-5-( 2,2-dlchloro-3-(3f5-dichlorophenyl )cyclopropane-l- carboxamido)- / V-(5-( methylthio)-lH-l,2,4-triazol-3-yl )benzamide (F184)CIIsolated as an off-white foam (0.085 g, 59.4%) .trans-2-Chloro-5-( 2,2-dlchloro-3-(3f5-dichlorophenyl )cyclopropane-l- carboxamldo)- / V-(4-(p-tolyl )thlazol-2-yl )benzamlde (PF136)CIIsolated as an off-white solid (0.087 g, 56.7%).trans-tert-Butyl (4-(2-chloro-5-(2,2-dlchloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlmethyl phenyl )( methyl )carbamate ( F618)CICH3CH3Isolated as an off-white foam (0.041 g, 43%) .trans-tert-Butyl (5-(2-chloro-5-(2,2-dlchloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamido)-2- methyl phenyl )( methyl )carbamate ( F619)Isolated as an off-white foam (0.064 g, 75%) .trans-tert-Butyl (5-(2-chloro-5-(2,2-dlchloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamido)-2- methyl phenyl )carbamate (F620)Isolated as an off-white foam (0.104 g, 52%) .5-(trans)-2-Bromo-2-chloro-3-( 3,5-dichlorophenyl )cyclopropanecarboxamido)- 2-chloro-A / -(4-fluorophenyl )- / V-methylbenzamide ( F 167)Isolated as a white foam (0.128 g, 71.4%).5-(trans)-2-Bromo-2-chloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)-2-chloro-W-(2,6-dlf1uorophenyl)benzamide (F168)Br CICIIsolated as a white foam (0.096 g, 54.3%).A / -(5-Bromo-lH-indol-6-yl)-2-chloro-5-(trans)-2,2-dichloro-3-(3,5- dichlorophenyl)cyclopropane-l-carboxamido)benzamlde (F172)Isolated as a white foam (0.081 g, 27.8%).2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)-W-(4-f1uoro-lH-indol-6-yl)benzamlde (F173)Isolated as a gold oil (0.114 g, 41.9%).2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl)cyclopropane-l- carboxamldo)- / V-(lH-pyrrolo[2,3-£>]pyridin-6-yl)benzamide (F178)CI CICI N- Isolated as a white solid (0.121 g, 49.2%).5-(trans)-2-Bromo-2-chloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-2-chloro-W-(2,4-dlf1uorophenyl )benzamide (F187)CIIsolated as a white foam (0.171 g, 63.2%) .2-Chloro-5-(trans)-2,2-dichloro-3-(3-chloro-5-cyanophenyl )cyclopropane-l- carboxamldo)-W-(2,4-difluorophenyl )benzamide (F 188)Isolated as a white solid (0.105 g, 53.8%).2-Chloro-5-(trans)-2,2-dichloro-3-(3-chloro-5-cyanophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )-A / -methylbenzamide (F 189)Isolated as a gold foam (0.125 g, 64.6%).2-Chloro-5-( (2S)-2-chloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )benzamlde (F212)CIIsolated as a white solid (0.073 g, 27.7%).2-Chloro-5-( (2f?)-2-chloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(4-f1uorophenyl )benzamlde (F213)CIIsolated as a white solid (0.078 g, 29.5%).2-Chloro-5-( (2S)-2-chloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(2,4-difluorophenyl )benzamide (F214)Isolated as a white solid (0.109 g, 38. 1%).A / -(Benzo[d]thiazol-6-yl )-2-chloro-5-(trans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F434)Isolated as a white foam (0.055 g, 41.7%) .2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)- / V-( lH-lndol-5-yl )benzamide (F435)CIIsolated as a tan foam (0.030 g, 11.7%).2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(qulnolin-7-yl )benzamide (F436)Isolated as a tan foam (0.121 g, 46.4%).2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)- / V-( lH-pyrrolo[3,2-£>]pyridin-6-yl )benzamide (F437)Isolated as a tan foam (0.137 g, 53.5%).2-Chloro-A / -(2-chloro-lH-benzo[d]imidazol-6-yl )-5-(trans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F438)Isolated as a pale yellow solid (0. 101 g, 37.2%) .v-(Benzo[d]thiazol-2-yl )-2-chloro-5-(trans)-2,2-dichloro-3-( 3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamide (F441 )CIIsolated as a white solid (0.038 g, 19.22%).2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamido)-A / -(5-fluorobenzo[d]thiazol-2-yl )benzamide (F442)Isolated as a white solid (0.109 g, 53.5%).2-Chloro- / V-(4-chlorobenzo[d]thiazol-2-yl )-5-( trans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamide (F443)Isolated as a white solid (0.073 g, 34.9%).2-Chloro-5-( trans)-2, 2-dichloro-3-(3, 5-dichloropheny I )cyclopropane-l- carboxamido)-A / -(5,6-dichlorobenzo[i / ]thiazol-2-yl )benzamide ( F444)CI CIIsolated as a white solid (0.097 g, 43.9%).2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(6-fluorobenzo[d]thiazol-2-yl )benzamide (F445)CI CIFIsolated as a white solid (0.122 g, 59.9%). / V-(Benzo[d]oxazol-2-yl )-2-chloro-5-(trans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F447)Isolated as a white solid (0.032 g, 16.6%).2-Chloro- / V-(5-chlorobenzo[d]oxazol-2-yl )-5-(trans)-2,2-dlchloro-3-(3f5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F448)Isolated as a white solid (0.062 g, 30.4%).2-Chloro-5-(trans)-2, 2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)- v-(4-f1uoro-l-methyl-lH-indazol-3-yl )benzamide (F449)'N\CH3Isolated as a white foam (0.020 g, 9.9%).V-(Benzo[d]oxazol-6-yl )-2-chloro-5-(trans)-2,2-dichloro-3-(3,5- dichlorophenyl )cyclopropane-l-carboxamido)benzamlde (F450)CIIsolated as a tan foam (0.028 g, 14.6%).2-Chloro-5-(trans)-2,2-dichloro-3-(3,5-dichlorophenyl )cyclopropane-l- carboxamldo)-W-(...

Claims

------04 / 01 / 2561------(OCR) Page 1 of 22 pages. Claims 1. Molecules with the following formula (chemical formula) Formula I, where:(A) R1 is chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl, S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(B) R2 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl, (C1-C6)Halo Alkoxy,S(C1-C6)Alkyl,S(O)(C1-C6)Alkyl,S(O)2(C1-C6)Alkyl,S(C1-C6)Halo Alkyl,S(O)(C1-C6)Halo Alkyl,S(O)2(C1-C6)Halo Alkyl,(C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalkyl-S(O)2NH2;(C)R3 were selected from the group containing H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy, (C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,Page 2 of 22 pagesS(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)halocalkyl-S(O)2NH2;(D) R4 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkenil, (C3-C6) cycloalkenil, (C2-C6) calkinil, (C1-C6) calcoxy. (C1-C6)halocalkyl,(C3-C6)halocyclocalkyl,(C2-C6)halocalkinyl,(C3-C6)halocyclocalkinyl,(C1-C6)ralocalcoxyl,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)halocalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,(C1-C6)calkyl-S(O)2NH2 and(C1-C6)halocalkyl?S(O)2NH2;(E) R5 was selected from the group containing H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)calkyl,(C3-C6)cyclocalkyl,(C2-C6)calkinil,(C3-C6)cyclocalkinil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocyclocalkyl,(C2-C6)halocalkinil,(C3-C6)halocyclocalkinil ,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)halocalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,(C1-C6)calkyl-S(O)2NH2 and(C1-C6)halocalkyl-S(O)2NH2;(F) R6 was selected from the group consisting of H and (C1-C6) calkyl;(G) R7 was selected from the group consisting of H, F, Cl, Br and I;(H) R8 was selected from the group consisting of F, Cl, Br and I;(I) R9 was selected from the group consisting of H and (C1-C6) calkyl;(J) Q1 was selected from the group consisting of O and S;(K) Q2 was selected from the group consisting of O and S;(L) R10 was selected from the group consisting of H, (C1-C6) calkyl, (C2-C6) calkinil, (C1-C6) halocalkyl, (C1-C6) calkyl, (C1-C6) calcoxi, C(=O)(C1-C6) calkyl and (C1-C6) calcoxi C(=O)(C1-C6) calkyl;(M) R11 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)calkis,(C3-C6)cyclocalkyl,(C2-C6)calkenil,(C3-C6)cyclocalkenil,(C2-C6)calkinil.(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkyl,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (N) R12 Selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alxoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6 )haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1- C6)haloalkyl-S(O)2NH2;(a) X1 was selected from the group consisting of (7) N,(8) NO and (9) CR13 where R13 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2 and triazolyl;(P) X2 were selected from the group consisting of (7) N,(8) NO and (9). CR14 is page 4 of 22, in which R14 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1- C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(Q)X3 were selected from the group consisting of N(R15)(substituted or unsubstituted phenyl),N(R15)(substituted or unsubstituted heterocyclyls) and substituted or unsubstituted heterocyclyls (a) where such R15 is chosen from a group consisting of H,(C1-C6)alkyl,(C2-C6)alkinyl,(C2-C6)alkinyl,(C1-C6)haloalkyl,(C1-C6)alkyl(C1-C6)alkoxy,C(=O)(C1-C6)alkyl and(C1-C6)alkoxyC(=O)(C1-C6)alkyl(b) where such substituted phenyls and substituted heterocyclyls have one or more representatives chosen from a group consisting of F,Cl,Br,I,H,CN,CHO,NHOH,NO,NO2, OH,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)alkylphenyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkyl-S(O)2NH2,(C2-C6)alkinyl,(C2-C6)alkinyl,(C2-C6)haloalkinyl,(C3-C6)cycloalkinyl,( C3-C6)cycloalkyl,(C3-C6)halocycloalkenil,(C3-C6)halocycloalkyl,(C1-C6)alkyl((C1-C6)alkyl)(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,C(O)(C1-C6)alkyl,C(O)NH(C1-C6)alkyl,C(O)NHphenyl,C(O)O(C1-C6)alkyl, CH(=NO(C1-C6)alkyl),imidazolyl,N((C1-C6)alkyl)(C(O)(C1-C6)alkyl),N((C1-C6)alkyl)(C(O)(C1-C6)alkyl-O(C1-C6)alkyl),N((C1-C6)alkyl)(C(O)(C1-C6)haloalkyl),N((C1-C6)alkyl)(C(O)O(C1-C6)alkyl),N((C1-C6)alkyl)2,N(C(O)O(C1-C6)alkyl)2,N=CH-phenyl, NH((C1-C6)alkylC(O)(C1-C6)alkyl),NH(C(O)(C1-C6)alkyl),NH(C(O)(C2-C6)alkinyl),NH(C(O)(C3-C6)cycloalkyl),NH(C1-C6)alkyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl,NH(C1-C6)alkylphenyl, NH(S(O)2(C1-C6)alkyl),NH2,NHC(O)(C1-C6)alkyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)page 5 of 22 pages alkylphenyl,NHC(O)(C1-C6)haloalkyl,NHC(O)(C2-C6)alkenyl,NH-C(O)O(C1-C6)alkyl,oxazolyl,aunyl,pyrazolyl Pyridinil, S(=NCN)((C1-C6)alkyl, S(C1-C6)alkyl, S(C1-C6)haloalkyl, S(O)(=NCN)((C1-C6)alkyl, S(O)(C1-C6)alkyl, S(O)(C1-C6)haloalkyl, S(O)2(C1-C6)alkyl, S(O)2(C1-C6)haloalkyl, SCN, thiazolyl, thienyl, and triazolyl Where Alcoxi, Alkyl, Halo Alcoxi, Halo Alkyl, Alkinil, Alkinil, Halo Alkinil, Cyclo Alkinil, Cyclo Alkyl, Halo Cyclo Alkinil, Halo Cyclo Alkinil, Imidazolil, Phenyl, Pyrazolil, Pyridinil, Thiazolil,Each thienyl and triazolyl may be alternatively substituted by one or more substitutes selected from the group comprising F, Cl, Br, I, CN, OH, NH(C1-C6) alkyl, NH(C3-C6) cycloalkyl, CH2O(C1-C6) alkyl, NH(C3-C6) cycloalkyl, CH2O(C1-C6) haloalkyl, NHCH2(C3-C6) cycloalkyl, NH2, NO2, oxo, (C1-C6) alkyl, (C1-C6) alkyl, (C1-C6) alkoxy and C(O)O-(C1-C6) alkyl; and N-oxides, acid-additive salts, salt derivatives, solvates, ester derivatives, crystalline polymorphs, isotopes, isolated stereoisomers and agriculturally acceptable toutomers of the first formula molecule.

2. Molecules according to claim 1 where X3 is chosen from a group consisting of (chemical formula) page 6 of 22 pages (chemical formula) page 7 of 22 pages (chemical formula) where:(a) R15 is chosen from a group consisting of H,(C1-C6)alkyl,(C2-C6)alkenil,(C2-C6)alkinil,(C1-C6)haloalkyl,(C1-C6)alkyl(C1-C6)page 8 of 22 pages C6)alkoxy,C(=O)(C1-C6)alkyl and(C1-C6)alkoxyC(=O)(C1-C6)alkyl;(b) X4 is chosen from a group consisting of (i)N,(ii)NO and (iii)CR16, where R16 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocalkyl, (C2-C6)halocyclokinil,(C3-C6)halocyclokinil,(C1-C6)haloalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)calkyl,S(C1-C6)halocyclokinil,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,(C1-C6)alkyl-C(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2 where each alkyl, cycloalkyl, alkenyl, cycloalkinyl, alkinyl, alkoxy, haloalkyl, halocycloalkyl, haloalkinyl, halocycloalkinyl and haloalkoxy may be alternatively replaced by one or more representatives chosen from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2, oxo,(C1-C6)calkyl,(C1-C6)calkoxy and C(O)O-(C1-C6)alkyl; (c) Xs is chosen from the group consisting of (i) N,(ii) NO and (iii) CR17, where R17 is chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)calkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalky,page 9 of 22,(C2-C6)alkynyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,( C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,C(O)O(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(d) X6 was selected from the group consisting of(i)N,(ii) NO and(iii). And CR18, where R18 was selected from a group consisting of H,F,Cl,Br,I,CN,NO2,OH,NH2,SCN,CHO,(C1-C6)alkyl,(C2-C6)alkinyl,(C2-C6)alkinyl,(C1-C6)haloalkyl,(C1-C6)alcoxy,(C1-C6)haloalcoxy,NH(C1-C6)alkyl,N((C1-C6)alkyl)2,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1 -C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl,CONH(C1-C6)alkyl,NHCO(C1-C6)alkyl,N(C1-C6)alkyl-CO(C1-C6)alkyl,NHCO(C2-C6)alkenyl,NHCO(C3-C6)cycloalkyl,NHCO(C1-C6)haloalkyl,N(C1-C6)alkyl-CO(C1-C6)haloalkyl,NHCO(C1-C6)alkylphenyl,NH-C(O)O(C1-C6)alkyl,N(C1-C6)alkyl-C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,phenyl,pyrazolyl,imidazolyl and triazolyl where alkyl,alkinyl,alkinyl,haloalkyl,alcoxy,haloalcoxy,halocycloalky Each of the cycloalkyl, phenyl, imidazolyl and triazolyl may be alternatively replaced by one or more substitutes chosen from the group consisting of F, Cl, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6) alkyl, (C1-C6) alkoxy and C(O)O-(C1-C6) alkyl; page 10 of page 22(e) X7 is chosen from the group consisting of (i) N, (ii) NO and (iii). CR19, where R19 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocyclol. Alkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalcoxy,S(C1-C6)alkyl,S(0)(C1-C6)alkyl,S(0)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,C(O)O(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalkyl-S(O)2NH2;(f) X8 was selected from the group consisting of (i) N,(ii) NO and (iii) CR20 where R20 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinyl,(C 3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,C(O)O(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(g) R21 Selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alxoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl, Page 11 of 22 (C2-C6) Haloalkinil, (C3-C6) Halocycloalkinil, (C1-C6) Haloalkoxy, S(C1-C6) Alkyl, S(O)(C1-C6) Alkyl, S(O)2(C1-C6) Alkyl, S(C1-C6) Haloalkyl, S(O)(C1-C6) Haloalkyl, S(O)2(C1-C6) Haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl, where each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy,phenyl, imidazolyl and triazolyl may be alternatively substituted by one or more substitutes chosen from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl(h). R22 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alcoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalcox. ,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyricinyl and thienyl where alkyl,alkinyl,alkinyl,haloalkyl,alcoxy,haloalcoxy,phenyl,Each imidazolyl and triazolyl may be alternatively substituted by one or more representatives chosen from the group consisting of F,C1,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(0)0-(C1-C6)alkyl(i). R23 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkinil,S(O)(C1-C6). Page 12 of the list. Page 22 of the haloalkyl,S(O)2(C1-C6)halocalkyl,(C1-C6)calkyl-S(O)2NH2,(C1-C6)halocalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl, in which calkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy,phenyl,imidazolyl and triazolyl each may be alternatively replaced by one or more substitutes chosen from the group consisting of F,C1,Br,I,CN,OH,NH2,NO2,oxo,(C2-C6)alkyl,(C2-C6)alkoxy and C(O)O-(C2-C6)alkyl(j) R24 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calkoxy,(C1-C6)halocalkyl,(C3-C6)ha Locycloalkyl,(C2-C6)halocalkinil,(C3-C6)halocalkinil,(C1-C6)halocalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6 )haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)halocalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl, where each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl and triazolyl may be alternatively substituted by one or more substitutes selected from the group consisting of F,C1,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6alkoxy and C(O)O-(C1-C6)calkyl3. A molecule under claim 1 where X3 is a substituted or unsubstituted heterocyclic where such heterocyclic is chosen from a group consisting of indolyl, oxazolyl, pyrazinil, pyrazolil, pyridyl, pyrimidinil,Tetrazolyl, thiadiazolyl, thiazolyl, thienyl, triazinyl,[1,2,4]triazolo[l,5-c]pyrimidinyl, triazolyl, 2,r-dihydrophthalasine-1,4-dionyl, indolinyl and pyrimidine-2,4(1H,3H-dionyl) page 13 of 22 functions in which representatives were selected from the group consisting of F,Cl,Br,I,H,CN,NH2,NO2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C2-C6)haloalkenyl,(C3-C6)halocycloalkenyl and (C3-C6)halocycloalkyl4. The molecule according to claim 1, where X3 is a substituted or unsubstituted heterocyclic, where such heterocyclic is chosen from the group consisting of indolinil, oxavolil, pyridyl and thiadiazolyl, which is represented by a group consisting of F, Cl, Br, I, FI, CN, NO2, NH2, (C1-C6) alkoxy, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) haloalkinyl, (C2-C6) haloalkenyl.(C3-C6)halocycloalkenil and (C3-C6)halocycloalkyl5. The molecule according to claim 1, where X3 is N(R15)(substituted or unsubstituted phenyl)(a) where such R15 is chosen from the group containing H and (C1-C6) alkyl(b) where such substituted phenyl has one or more representatives chosen from the group containing F,Cl,Br,I,CN,NO2,NH2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C2-C6)haloalkenyl,(C3-C6)cycloalkenyl,(C3-C6)cycloalkyl,(C3-C6)halocycloalkenyl and(c3-c6)halocycloalkyl6. The molecules according to claim 1 are:(A) R1, R2, R3, R4, R5, R11 and R12 each freely chosen from the group consisting of H, F, Cl, Br, (C1-C6) alkyl, (C1-C6) haloalkyl and (C1-C6) haloalkoxy;(B) R6 and r' are H;(C) R7 is chosen from the group consisting of C1 and Br;(D) R8 is chosen from the group consisting of C1 and Br;(E) Q1 and Q2 each freely chosen from the group consisting of o and S;(F) R10 is H;(G) X1 is chosen from the group consisting of (4) N, (5) NO and page 14 of the 22 pages;(6) CR13 where R13 is chosen from the group consisting of H, F, Cl, Br, I, CN,(C1-C6)alkyl,(C1-C6)alcoxy,(C1-C6)haloalkyl,(C1-C6)haloalcoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl and triazolyl; (H) X2 was chosen from the group consisting of (3) N and (4) CR14, where R14 was chosen from the group consisting of H, F, C1 and (C1-C6) alkoxy; (I) X3 was chosen from the group consisting of (chemical formula) where: page 15 of 22 pages; (h) R15 was chosen from the group consisting of H, (C,-C6) alkyl, (C2-C6) alkenyl and (C1-C6) haloalkyl; (i) X4 was chosen from the group consisting of (i) N and (ii) CR, where R16 was chosen from the group consisting of H, F, Cl, CN, NH2 and (C1-C6) alkyl; (j) X5 was chosen from the group consisting of (iv) N, (v) NO and (vi) CR17, where R17 was chosen from the group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from the group consisting of (iv) N,(v) NO and (vi) and CR18 where R18 was selected from the group consisting of H,F,Cl,CN,NO2,NH2(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy,(C1-C6)haloalkoxy, S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,CONH(C1-C6) alkyl and NHCO(C1-C6) alkyl;(l) X7 is CR19 in which R19 is chosen from the group consisting of H, NH2 and F;(m) X8 is CR20 page 16 of 22 pages in which R20 is chosen from the group consisting of H, F, Cl, NH2 and (C1-C6) alkyl; and(n) R21, R22, R23 and R24 are H7 molecules according to claim 1 in which(A) R1 is H;(B) R2 is chosen from the group consisting of H, Cl, Br, (C1-C6) alkyl and (C1-C6) haloalkyl;(C) R3 is chosen from the group consisting of H, F, Cl, Br, (C1-C6) alkyl, (C1-C6) haloalkyl and (C1-C6) haloalkoxy;(D) R4 was chosen from the group consisting of H, Cl, Br, (C1-C6) alkyl and (C1-C6) haloalkyl;(E) R5 was chosen from the group consisting of H and C1;(F)R6 is H;(G) R7 was chosen from the group consisting of C1 and Br;(H) R8 was chosen from the group consisting of C1 and Br;(I) R9 is H;(J) Q1 is O;(K) Q2 was chosen from the group consisting of o and r;(L) R10 is H;(M) R11 was chosen from the group consisting of H, F, C1 and (C1-C6) alkyl;(N) R12 was chosen from the group consisting of H and C1;(O) X1 was chosen from the group consisting of (1) N,(2) NO and page 17 of the 22 pages (3)CR13 where R13 was chosen from the group consisting of H, F, Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alcoxy,(C1-C6)haloalkyl,(C1-C6)haloalcoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl and triazolyl; (P) X2 was chosen from a group consisting of (1) N and (2) CR14, where R14 was chosen from a group consisting of H, F, C1 and (C1-C6) alkoxy; (Q) X3 was chosen from a group consisting of (chemical formula) and (chemical formula), where page 18 of 22 pages; (h) R15 was chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkynyl and (C1-C6) haloalkyl; (i) X4 was chosen from a group consisting of (i) N and (ii)CR16 where R16 was chosen from a group consisting of H,F,Cl,CN,NH2 and (C1-C6) alkyl; (j) X5 was chosen from a group consisting of (i)N,(ii)NO and (iii)CR17 where R17 was chosen from a group consisting of H,F,Cl,NH2 and CN; (k) X6 was chosen from a group consisting of (i)N,(ii)NO and (iii) and CR18 where R18 was chosen from a group consisting of H,F,Cl,CN,NO2,NH2,(C1-C6) alkyl,(C1-C6) halo alkyl,(C1-C6) alkoxy,(C1-C6) halo alkoxy, S(C1-C6) alkyl,S(O)(C1-C6) alkyl,S(O)2(C1-C6) alkyl,CONH(C1-C6) alkyl and NHCO(C1-C6) alkyl;(l) X7 is CR19, where R19 is chosen from the group consisting of H, NH2 and F;(m) X8 is CR20, page 19 of number 22, where R20 is chosen from the group consisting of H, F, Cl, NH2 and (C1-C6) alkyl; and(n) R21, R22, R23, and R24 are H8. molecules according to claim 1 where: (A) R1 is chosen from the group consisting of H, F, or C1;(B) R2 is chosen from the group consisting of H, F, Cl, Br, (C1-C6) alkyl and (C1-C6) haloalkyl;(C) R3 was selected from the group consisting of H,F,Cl,Br,(C1-C6)alkyl,(C1-C6)haloalkyl, and(C1-C6)haloalcoxy; (D) R4 was chosen from the group consisting of H,F,Cl,Br,(C1-C6)alkyl and (C1-C6)haloalkyl;(E) R5 was chosen from the group consisting of H,F and C1;(F) R6 is H;(G) R7 was chosen from the group consisting of C1 and Br;(H) R8 was chosen from the group consisting of C1 and Br;(I) R9 is H;(J) Q1 is O;(K) Q2 was chosen from the group consisting of O and S;(L) R10 is H;(M) R11 was chosen from the group consisting of H,F,C1 and (C1-C6)alkyl;(N) R12 was chosen from the group consisting of H and C1;(O) X1 is CR13, where R13 was chosen from the group consisting of H,F,Cl,Br,I,CN,(C1-C6) alkyl, (C1-C6) alkoxy, (C1-C6) halo alkyl and (C1-C6) halo alkoxy; page 20 of number 22 (P) X2 is CR14, where R14 was chosen from the group consisting of H, F, C1 and (C1-C6) alkyl, (C1-C6) alkoxy, (C1-C6) halo alkyl and (C1-C6) halo alkoxy; and (Q) X3 is where R15 was chosen from the group consisting of H, (C1-C6) alkyl, (C2-C6) alkynyl and (C1-C6) halo alkyl; X4 is CR16, where R16 was chosen from the group consisting of H, F, Cl, NH2jCN, NO2, (C1-C6)alkyl, (C1-C6)haloalkyl, (C1-C6)alkoxy and (C1-C6)haloalkoxy; X5 is CR17 where R17 was chosen from the group consisting of H,F,Cl,NH2CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X6 is CR18 where R18 was chosen from the group consisting of H,F,Cl,NH2CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X7 is CR19, where R19 was chosen from a group consisting of H,F,Cl,NH2CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy, and(C1-C6)haloalkoxy; X8 is CR20, where R20 was chosen from a group consisting of H,F,Cl,CN,NH2NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy molecules.

9. The molecules are selected from one of the following molecules: F1 to F249, F251 to F255, F257 to F268, F270 to F275, F277 to F320, F322 to F443, F445 to F465, F469, F471 to F488, F490 to F500, F502 to F506, F510, F511, F513 to F520, F524 to... F532, F537 to F599, PF1, PF2, PF4 to PF22, PF24 to PF58, PF60, PF62, PF65, PF67 to PF78, PF102, page 21 of 22 pages, PF104, PF107 to PF110, PF113 to PF119, PF122 to PF127, PF130, PF133 to PF136, PF138 to PF141, PF143, PF152, PF153, PF155, PF156, PF158.PF161 to PF16410. A process comprising one of the molecules described in points 1 to 9 and a carrier.

11. A process for insect control comprising the application of an effective insecticidal dose of one of the molecules described in points 1 to 10 to a specific location.

12. A process comprising (chemical formula) (chemical formula) the reaction of molecule 13-1 with (C1-C6) alkyl orthoformate in the presence of an acid with a pH between 0 and 5, where the reaction is carried out in a (C1-C6) alkanol solvent at temperatures from 0°C to ambient and under ambient pressure to produce molecule 13-2 in which R1, R2, R3, R4, R5, R6 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

13. A process comprising (chemical formula) (chemical formula) the reaction of 13-2 with a carbine source such as haloform in the presence of an inorganic alkali and a catalyst. Phase transfer reactions occur at temperatures ranging from approximately ambient temperature down to below the boiling point of haloforms to form 13-3 molecules in which R1, R2, R3, R4, R5, R6, R5, R7,R8 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl14. The process which includes (Chemical Formula) the conversion of 13-3 cyclopropyl acetal 13-3 to the aldehyde 13-4 in a polar solvent by the presence of an aqueous mineral acid at ambient temperature where R1, R2, R3, R4, R5, r', R5, R7, R8 and R9 satisfy claim 1.

15. The process which includes (Chemical Formula) the oxidation of 13-4 in a polar aprotic solvent at temperatures ranging from approximately 0°C to approximately ambient temperature where R1, R2, R3, R4, R5, R6, R7, R8 and R9 satisfy claim 1.------------------07 / 04 / 2016------(OCR) Page 1 of 19 Claim 1. A molecule with the following formula is one in which:(A) R1 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)calkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3C€6)cycloalkinil,(C2-C6)alkinil,(C,-C6)alkoxy,(C,-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(0)(C1-C6)alkyl,S(0)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(B) R2 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenyl,(C3-C6)cycloalkenyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkeni L,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalky]-S(O)2NH2;(C) R3 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)haloxy. Halocyclocalkinil,(C2-C6)halocalkinil,(C3-C6)halocyclocalkinil,(C1-C6)halocalkinil,S(C1-C6)calkil,S(O)(C1-C6)calkil,S(O)2(C1-C6)calkil,S(C1-C6)halocalkinil,S(O)(C1-C6)halocalkinil,S(O)2(C1-C6)halocalkinil,(C1-C6)calkyl-S(O)2NH2 and (C1-C6)haloalkyl-S(O)2NH2; page 2 of 19(D). R4 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenyl,(C3-C6)cycloalkenyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkeni L,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(E) R5 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,C(C1-C6)haloalkyl,(C3-C6)halosy. Colealkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalkyd-S(O)2NH2;(F) R6 was selected from the group containing H and (C1-C6)alkyl;(G) R7 was selected from the group containing H, F, Cl, Br and I;(H) R8 was selected from the group containing F, Cl, Br and I;(I) R9 was selected from the group containing H and (C1-C6)alkyl;(J) Q1 was selected from the group containing O and r;(K) (Q2 was selected from the group containing O and r;(L) R10 was selected from the group consisting of H,(C1-C6)alkyl,(C2-C6)alkinil,(C1-C6)haloalkyl,(C1-C6)alkyl,(C1-C6)alkoxy,C(=0)(C1-C6)alkyl and(C1-C6)alkoxyC(=0)(C1-C6)alkyl;(M). R11 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halosy. Colealkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalkyd-S(O)2NH2; page 3 of 19(N). R12 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenyl,(C3-C6)cycloalkenyl,(C2-C6)calkinyl,(C1-C6)alkoxy,(CrC6)haloalkyl,(C3-C6)halocyclo Haloalkyl,(C2-C6)haloalkenyl,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl, (C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(O) X1 was selected from a group consisting of (7)N,(8)NO and (9)CR13, where R13 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)halo. Alkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2 and triazolyl;(P)X2 was selected from the group containing (7)N,(8)NO and (9)CR14 where R14 was selected from the group containing H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl Haloalkinyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; Page 4 of 19 pages (Q) X3 was selected from a group consisting of N(RIS)(replaced or unreplaced phenyl), N(R15)(replaced or unreplaced heterocyclyl) and replaced or unreplaced heterocyclyl(a), where such R15 was selected from a group consisting of H,(C1-C6)alkyl,(C2-c6)alkinyl,(C2-C6)alkinyl,(C1-C6)haloalkyl,(C1-C6)alkyl(C1-C6)alcoxy,C(=0)(C1-C6)alkyl and (C1-C6)alkoxyC(=0)(C1-C6)alkyl(b) where such substituted phenyl and substituted heterocyclyls with one or more substitutes selected from the group consisting of F,Cl,Br,I,H,CN,CHO,NHOH,NO,N02,OH,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)alkylphenyl,(C1-C6)alkyl-S(0)2NH2,(C1-C 6)haloalkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkyl-S(O)2NH2,(C2-C6)alkinil,(C2-C6)alkinil,(C2-C6)haloalkinil,(C3-C6)cycloalkinil,(C3-C6)cycloalkyl,(C3-C6)halocycloalkinil,(C3-C6)halocycloalkyl,(C1-C6)alkyl((C1-C6)alkyl)(=NO(C1 -C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,C(O)(C1-C6)alkyl,C(O)NH(C1-C6)alkyl,C(O)NHphenyl,C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),imidazolyl,N((C1-C6)alkyl)(C(O)(C1-C6)alkyl),N((C1-C6)alkyl)(C(O)(C1-C6)alkyl-O(C1-C6)alkyl),N ((C1-C6)alkyl)(C(0)(C1-C6)haloalkyl),N((C1-C6)alkyl)(C(O)O(C1-C6)alkyl),N((C1-C6)alkyl)2,N(C(O)O(C1-C6)alkyl)2,N=CH-phenyl,NH((C1-C6)alkylC(O)(C1-C6)alkyl),NH(C(0)(C1-C6)alkyl),NH(C(O)(C2-C6)alkinyl),NH(C(O)(C3-C6)cycloalkyl),NH(C1-C6)alkyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl1NH(CrC6)alkylphenyl,NH(S(O)2(C1-C6)alkyl),NH2,NHC(O)(C1-C6)alkyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)haloalkyl,NHC(O)(C1-C6)alkinyl,NH-C(O)O(C1-C6)alkyl,oxazo Lil, phenyl, pyrazolyl, pyridinyl, S(=NCN)((C1-C6)alkyl), S(C1-C6)alkyl, R(C1-C6)haloalkyl, S(O)(=NCN)((C1-C6)alkyl), S(O)(C1-C6)alkyl, S(O)(C1-C6)haloalkyl, S(O)2(C1-C6)alkyl, S(O)2(C1-C6)haloalkyl, SCN, thiazolyl, thienyl and triazolyl where alkoxy, Alkyl, haloalkoxy, haloalkyl, alkenil, alkinil, haloalkenil, cycloalkenil, cycloalkyl, halocycloalkenil, halocycloalkyl, imidazolyl, phenyl, pyrazolyl, pyridinyl, thiazolyl, thienyl, and triazolyl may each be alternatively replaced by other agents. One or more selected from a group consisting of F, Cl, Br, I, CN, OH, NH(C1-C6) alkyl, NH(C3-C6) cycloalkyl, CH2O(C1-C6) alkyl, NH(C3-C6) cycloalkyl, CH2O(C,-C6) haloalkyl, NHCH2(C3-C6) cycloalkyl, NH2, NO2, oxo, (C1-C6) alkyl, (C1-C6) alkyl.(C1-C6c6)alkoxy and C(O)O-(C1-C6)alkyl; and N-oxides, agricultural acid-acidic salts, salt derivatives, solvates, ester derivatives, crystalline polymorphs, isotopes, isolated stereoisomers and tautomers of molecules with the formula one2. The molecules according to claim 1, where X3 is chosen from a group consisting of (1) formula, (2) formula, (3) formula, (4) formula, page 6 of 19 pages, (5) formula, (6) formula, (7) formula, (8) formula, (9) formula, (10) formula, (11) formula, page 7 of 19 pages, (12) formula, (13) formula, (14) formula, where: (a) R15 is chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl, (C1-C6) alkinyl, (C1-C6) haloalkyl, (C1-C6) alkyl, (C1-C6) alkoxy, C(=0)(C1-C6) alkyl and (C1-C6) alkoxyC(=O)(C1-C6) alkyl; (b) X4 was selected from a group consisting of (i) N,(ii) NO and (iii) CR16, where R16 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C,-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2, page 8 of 19 pages, which includes alkyl, cycloalkyl, alkynyl, cycloalkyl Alkinil, alkinil, alkoxy, haloalkyl, halocycloalkyl, haloalkinil, halocycloalkinil and haloalkoxy each may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)calkoxy and C(O)O-(C1-C6)alkyl;(c) Xs are selected from the group consisting of (i)N,(ii)NO and(iii)CR17. Where R17 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl. ,(C3-C6)halocycloalkyl,(C2-C6)halocalkinil,(C3-C6)halocycloalkinil,(C1-C6)halocoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halokyl,C(O)O(C1-C6)calkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)halokyl-S(O)2NH2;(d) was selected from the group consisting of(i) N,(ii) NO and(iii) and CR18 where R18 was selected from the group consisting of H,F,Cl,Br,I,CN,N02,OH,NH2,SCN,CHO,(C1-C6)alkyl,(C2-C6)calkinil,(c2-c6)calkinil,(C1-C6)halokyl,(C1-C6)alkoxy,(C1-C6)halokyl,NH(C1-C6)alkyl,N((C1-C6 )alkyl)2,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6alkyl,CONH(C1-C6)alkyl,NHCO(C1-C6)alkyl,N(C1-C6)alkyl-CO(C1-C6 )Alkyl,NHCO(C2-C6)Alkenyl,NHCO(C3-C6)Cycloalkyl,NHCO(C1-C6)Haloalkyl,N(C1-C6)Alkyl-CO(C1-C6)Haloalkyl,NHCO(C1-C6)Alkylphenyl,NH-C(O)O(C1-C6)Alkyl,N(C1-C6)Alkyl-C(O)O(C1-C6)Alkyl,CH(=NO(C1-C6) (Alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,phenyl,pyrazolyl,imidazoyl and triazolyl, page 9 of 19 pages, which includes alkyl, alkynyl, alkinyl, haloalkyl, alkoxy, haloalkoxy, halocycloalkyl, cyclocalkyl, phenyl,Each imidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F,Cl,Br,I,CN,OH,nh2,no2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl. (e) x7 is chosen from the group consisting of (i)N,(ii)NO and (iii)CR19 where R19 is chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(CC1-C6)haloalkyl,(C3-C6)halocyclol. Alkyl,(C2-C6)haloalkenyl,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,C(O)O(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (f) X8 was selected from a group consisting of (i)N,(ii) NO and (iii) CR20, where R20 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,N02,(C1-C6 alkyl,(C3-C6)cycloalkyl, (C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl,(C3-C6)halocycloalkenyl,(C1-C6)halocoxy,(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-c6)haloalkyl,c(o)o(c1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (g) R21 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkenil,(C3-C6)halocycloalkenil,(C1-C6)halocalkenil,S(C1-c6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-c6)calkyl,S(C1-c6)page 10 of 19 pages haloalkyl,S(( O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)calkoxy and C(O)O-(C1-C6)alkyl(h) R22 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6alkyl,(C3-C6)cycloalkyl,(c2-c6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)H Halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloclcoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6 )haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl, alkenyl, calkinyl, haloalkyl, alkoxy, haloclkoxy, phenyl, imidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl(i) R23 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alxoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil.(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where alkyl,alkenil Each of the alkinyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl(j). R24 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkynyl, (C3-C6) cycloalkynyl, (C2-C6) alkinyl, (C1-C6) alkyl (11 of 19), (C1-C6) haloalkyl, (C3-C6) halocycloalkyl, (C2-C6) H. Haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6haloalkyl-S(O)2NH2,phenyl,Pyridinyl and thienyl, where each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, inidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group comprising F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl3. A molecule under claim 1 where X3 is a substituted or unsubstituted heterocyclic where such heterocyclic is chosen from a group consisting of indolyl, oxazolyl, pyrazinil, pyrazolil, pyridazinil, pyridyl, pyrimidinil, tetrazolyl, thiadiazolyl, thiazolyl, thienil, triazinil,[1,2,4] ]Triazolo[1,5-c]pyrimidinil,triazolil,2,3-dihydrophthalazine-1,4-dionil,indolinil and pyrimidine-2,4(1H,3H / )-dionil, where the selected representatives are from the group consisting of F,Cl,Br,I,H,CN,NH2,NO2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C2-C6)haloalkenil,(C3-C6) halocycloalkenil and (C3-C6) halocycloalkyl4. Molecules according to claim 1, where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolinil, oxazolyl, pyridyl and thiadiazolyl, where such substitute is chosen from the group consisting of F, Cl, Br, I, H, CN, NO2, NH2, (C1-C6) alkoxy, (C1-C6) alkyl, (C1-C6) haloalkoxy, (C1-C6) haloalkyl, (C2-C6) haloalkenil, (C3-C6) halocycloalkenil and (C3-C6) halocycloalkyl5. The molecule according to claim 1 where X3 is N(R15)(substituted or unsubstituted phenyl)(a) where such R15fy is chosen from the group consisting of H and (C1-C6) alkyls; (b) where such substituted phenyl has one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, NO2, NH2, (C1-C6) alkoxy, (C1-C6) alkyl, (C1-C6) haloalkoxy, (C1-C6) haloalkyl, (C2-C6) haloalkenyl, (C3-C6) cycloalkenyl, (C3-C6) cycloalkyl, (C3-C6) halocycloylkenyl and (C3-C6) halocycloylkenyl. Page 12 of 19, page 6. The molecules according to claim 1 in which (A) R1,R2,R3,R4,R5,(B) R11 and R12 are each freely chosen from the group consisting of H, F, Cl, Br, (C1-C6) alkyl, (C1-C6) halo alkyl and (C1-C6) halo alkoxy; (C) R6 and R9 are H; (C) R7 is chosen from the group consisting of C1 and Br; (D) R8 is chosen from the group consisting of C1 and Br; (E) Q1 and Q2 are each freely chosen from the group consisting of O and S; (F) R10 is H; (G) x1 is chosen from the group consisting of; (4) N, (5) NO and (6) CR13 where R13 was chosen from the group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl and triazolyl;(H) x2 was chosen from the group consisting of (I)(3) N and (4). CR14 where R14 was chosen from the group consisting of H,F,C1 and (C1-C6)alkoxy;(I)X3 was chosen from the group consisting of (3)formula,(4)formula, page 13 of 19 pages. R15 where (h) R15 was chosen from the group consisting of H,(C1-C6)alkyl, (C2-C6)alkenyl and (C1-C6)haloalkyl;(i) X4 was chosen from the group consisting of (i) N and (ii) CR16 where R16 was chosen from the group consisting of H,F,Cl,CN,(j) Xs was selected from the group consisting of (iv) N, (v) NO and (vi) CR17, where R17 was selected from the group consisting of H, F, Cl, NH2 and CN; (k) X6 was selected from the group consisting of (iv) N, (v) NO and (vi) and CR18, where R18 was selected from the group consisting of H, F, Cl, CN, NO2, NH2(C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy, (C1-C6) haloalkoxy, S(C1-C6) alkyl, S(O)(C1-C6) alkyl, S(O)2(C1-C6) alkyl, CONH(C1-C6) alkyl and NHCO(C1-C6) alkyl; (I) X7 is CR19, where R19 was chosen from the group consisting of H, NH2, and F; page 14 of 19 pages (m)X8 is CR20, where R20 was chosen from the group consisting of H, F, Cl, NH2, and (C1-C6) alkyl; and (n)R21,R22,R23, andR24 are H7 molecules according to claim 1, where (A)R1 is H; (B) R2 was chosen from the group consisting of H, Cl, Br, (CrC6) alkyl, and (C,-c6) haloalkyl; (C) R3 was chosen from the group consisting of H, F, Cl, Br, (C,-C6) alkyl, (C,-c6) haloalkyl, and (C1-C6) haloalkoxy; (D) R4 was chosen from the group consisting of H, Cl, Br,(C1-C6) alkyl and (C1-C6) haloalkyl; (E)R5 was chosen from the group consisting of H and C1; (F)R6 is H; (G)R7 was chosen from the group consisting of C1 and Br; (H)R8 was chosen from the group consisting of C1 and Br; (I)R9 is H; (J)Q1 is 0; (K)Q2 was chosen from the group consisting of O and S; (L)R10 is H; (M)R11 was chosen from the group consisting of H, F, C1 and (C1-C6) alkyl; (N)R12 was chosen from the group consisting of H and C1; (O)X1 was chosen from the group consisting of (1)N, (2) NO and (3). CR13 where R13 was chosen from the group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1C6)alkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl and triazolyl; page 15 of 19 pages (P). X2 was chosen from the group consisting of (1) N and (2). CR14 where R14 was chosen from the group consisting of H,F,C1 and (c1-c6)alkoxy; and (Q) X3 was chosen from the group consisting of (3)formula,(4)formula,(5)formula and (6)formula where (h) R15 was chosen from the group consisting of H,(C1-C6)alkyl,(C1-C6) alkyl and (C1-C6) haloalkyl; (i) X4 was chosen from the group consisting of (i) N and (ii) CR16, where R16 was chosen from the group consisting of H,F,Cl,CN,NH and (C1-C6) alkyl on page 16 of 19; (j) X5 was chosen from the group consisting of (i) N, (ii) NO and (iii) CR17, where R17 was chosen from the group consisting of H,F,Cl,NH2 and CN; (k) X6 was chosen from the group consisting of (i) N, (ii) NO and (iii) (I) X7 is CR19, where R19 was chosen from the group consisting of H, NH2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy, (C1-C6) haloalkoxy, S(C1-C6) alkyl, S(O)(C1-C6) alkyl, S(O)2(C1-C6) alkyl, CONH(C1-C6) alkyl and NHCO(C1-C6) alkyl; (m) X8 is CR20, where R20 was chosen from the group consisting of H, F, Cl, NH2 and (C1-C6) alkyl; and (n) R21, R22, R23 and R24 are H8. The molecule pursuant to claim 1, where:(A) R1 is chosen from a group consisting of H,F, or C1;(B) R2 is chosen from a group consisting of H,F,Cl,Br,(C1-C6)alkyl and (C1-C6)haloalkyl;(C) R3 is chosen from a group consisting of H,F,Cl,Br,(C1-C6)alkyl,(C1-C6)haloalkyl and (C1-C6)haloalkoxy;(D) R4 was chosen from the group consisting of H,F,Cl,Br,(C1C6)alkyl and (C1-C6)haloalkyl;(E) R5 was chosen from the group consisting of H,F and C1;(F) R6 is H; page 17 of 19 pages(G) R7 was chosen from the group consisting of C1 and Br;(H) R8 was chosen from the group consisting of C1 and Br;(I) R9 is H;(J) Q1 is O;(K) Q2 was chosen from the group consisting of O and S;(L) R10 is H;(M) R11 was chosen from the group consisting of H,F,C1 and (C1-C6)alkyl;(N) R12 was chosen from the group consisting of H and C1;(O) X1 is CR13 where R13 was chosen from a group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alcoxy,(C1-C6)haloalkyl and(C1-C6)haloalcoxy;(P) X2 is CR14 where R4 was chosen from a group consisting of H,F,C1 and(C1-C6)alkyl,(C1-C6)alcoxy,(C1-C6)haloalkyl and(C1-C6)haloalcoxy; and(Q) X3 is the formula where R15 is chosen from the group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl and (C1-C6) haloalkyl; X4 is CR16 where R16 is chosen from the group consisting of H, F, Cl, NH2, CN, NO2, (C1-C6) alkyl, (C1-C6) haloalkyl.(C1-C6)alkoxy and (C1-C6)haloalkoxy; X5 is CR17 where R17 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X6 is CR18 where R18 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy. Page 18 of 19 of X7 is CR19, where R19 was chosen from the group consisting of H,F,Cl,NH2CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; X8 is CR20, where R20 was chosen from the group consisting of H,F,Cl,CN,NH2NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; 9. The molecule according to claim 1, which is selected from one of the following molecules: F1 to F249, F251 to F255, F257 to F268, F270 to F275, F277 to F320, F322 to F443, F445 to F465, F469, F471 to F488, F490 to F5. 00, F502 to F506, F510, F511, F513 to F520, F524 to F532, F537 to F599, PF1, PF2, PF4 to PF22, PF24 to PF58, PF60, PF62, PF65, PF67 to PF78, PF102, PF104, PF107 to PF110, PF113 to PF119, PF122 to PF127, PF130, PF133 to PF136.PF138 to PF141, PF143, PF152, PF153, PF155, PF156, PF158, PF161 to PF16410. A composition consisting of one of the molecules under claims 1 to 9 and a carrier.

11. A process to control pests, such a process consisting of the application to the site with an effective pest-eliminating quantity of one of the molecules under claims 1 to 10.

12. A process consisting of formula a, formula 13-113-2, in which molecule 13-1 reacts with (C1-C6) alkyl orthoformate in the presence of an acid with a pH between 0 and 5, where the reaction is carried out in a (C1-C6) alkanol solvent at a temperature from 0°C to ambient temperature and under ambient pressure to form molecule 13-2 in which R1, R2, R3, R4, R5,R6 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

13. The process, which includes page 19 of the formula b, formula 13-213-3, causes 13-2 to react with a carbine source such as haloform in the presence of an inorganic alkali and a phase-transfer catalyst at temperatures from approximately ambient temperature down to below the boiling point of haloform to form 13-3 molecules in which R1, R2, R3, R4, R5, R6, R5, R7, R8 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

14. The process comprising formula c13-313-4 involves the conversion of cyclopropyl acetal 13-3 to the aldehyde 13-4 in a polar solvent in the presence of an aqueous mineral acid at ambient temperature where R1, R2, R3, R4, R5, R6, R5, R7, R8, and R9 satisfy claim 115. The process comprising formula d13-41-3 involves the oxidation of 13-4 in a polar aprotic solvent at temperatures ranging from approximately 0°C to approximately ambient temperature where R1, R2, R3, R4, Rs, R6, R7, R8, and R9 satisfy claim 115.R8 and R9 comply with claim 1------------------07 / 04 / 2016------(OCR)Page 1 of 19 pages. Claim 1. A molecule with the following formula in which:(A) R1 is chosen from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)calkyl,(C3-C6)cycloalkyl,(C2-C6)alkenyl,(C3C€6)cyclocalkenyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C,-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl L,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(0)(C1-C6)alkyl,S(0)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(B) R2 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkinil, (C3-C6) cycloalkinil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalky]-S(O)2NH2;(C)R3 were selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocyclocalkyl,(C2-C6)halocalkenil,(C3-C6)H Halocyclocalcinyl,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)halocalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,(C1-C6)calkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; Page 2 of 19 (D) R4 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkenil, (C3-C6) cycloalkenil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) halocycloalkyl, (C2-C6) haloalkinine. L,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(E) R5 was selected from the group containing H,F,Cl,Br,I,CN,NH2,N02,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,C(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil ,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(F) R6 was selected from the group containing H and (C1-C6) alkyls;(G) R7 was selected from the group containing H, F, Cl, Br and I;(H) R8 was selected from the group containing F, Cl, Br and I;(I) R9 was selected from the group containing H and (C1-C6) alkyls;(J) Q1 was selected from the group containing O and r;(K) Q2 was selected from the group containing O and r;(L) R10 was selected from the group containing H, (C1-C6) alkyls, (C2-C6) alkenyls, (C1-C6) haloalkyls, (C1-C6) alkyls, (C1-C6) alkoxys, C(=0)(C1-C6) alkyls and (C1-C6) alkoxys C(=0)(C1-C6) alkyls;(M) R11 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl.(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2; Page 3 of 19 pages (N) R12 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)alkoxy,(CrC6)haloalkyl,(C3-C6)haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl, (C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalkyl-S(O)2NH2;(O) X1 was selected from the group consisting of (7)N,(8)NO and (9)CR13 where R13 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2 and triazolyl;(P) X2 was selected from a group consisting of (7)N,(8)NO and (9)CR14, where R14 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl. Page 4 of 19(Q) X3 was selected from the group consisting of N(RIS)(replaced or unreplaced phenyls),N(R15)(substituted or unsubstituted heterocyclyls) and substituted or unsubstituted heterocyclyls(a) where such R15 is selected from a group consisting of H,(C1-C6)alkyl,(C2-c6)alkinyl,(C2-C6)alkinyl,(C1-C6)haloalkyl,(C1-C6)alkyl(C1-C6)alkoxy,C(=0)(C1-C6)alkyl and(C1-C6)alkoxyC(=0)(C1-C6)alkyl(b). where such substituted phenyls and substituted heterocyclyls with one or more substitutes selected from the group consisting of F,Cl,Br,I,H,CN,CHO,NHOH,NO,NO2,OH,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)alkylphenyl,(C1-C6)alkyl-S(0)2NH2,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkyl-S(O)2NH2,(C2-C6)alkinyl,(C2-C6)alkinyl ,(C2-C6)haloalkenil,(C3-C6)cycloalkenil,(C3-C6)cycloalkyl,(C3-C6)halocycloalkenil,(C3-C6)halocycloalkyl,(C1-C6)alkyl((C1-C6)alkyl)(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,C(O)(C1-C6)alkyl,C(O)NH(C1-C6)alkyl,C(O)NHphenyl,C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),imidazolyl,N((C1-C6)alkyl)(C(O)(C1-C6)alkyl),N((C1-C6)alkyl)(C(O)(C1-C6)alkyl-O(C1-C6)alkyl),N((C1-C6)alkyl)(C(0)(C1-C6)haloalkyl),N((C1-C6)alkyl)(C(O)O(C1-C6)alkyl),N((C1-C6)alkyl)2,N(C(O)O(C1-C6)alkyl)2,N=CH-phenyl,NH((C1-C6)alkylC(O)(C1-C6)alkyl),NH(C(0)(C1-C6)alkyl) ,NH(C(O)(C2-C6)alkinyl),NH(C(O)(C3-C6)cycloalkyl),NH(C1-C6)alkyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl1NH(CrC6)alkylphenyl,NH(S(O)2(C1-C6)alkyl),NH2,NHC(O)(C1-C6)alkyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)halo Alkyl,NHC(O)(C1-C6)alkinyl,NH-C(O)O(C1-C6)alkyl,oxazolyl,phenyl,pyrazolyl,pyridinyl,S(=NCN)((C1-C6)alkyl),S(C1-C6)alkyl,r(C1-C6)haloalkyl,S(O)(=NCN)((C1-C6)alkyl),S(O)(C1-C6)alkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)alkyl,S(O)2( C1-C6) Haloalkyl, SCN, Thiazolyl, Thienyl and Triazolyl, where alkoxy, alkyl, haloalkoxy, haloalkyl, alkenyl, alkinyl, haloalkenyl, cycloalkenyl, cycloalkyl, halocycloalkenyl, halocycloalkyl, imidazoyl, phenyl, pyrazolyl, pyridinyl, thiazoyl.Each thienyl and triazolyl may be alternatively replaced by one or more substitutes selected from the group consisting of F,Cl,Br,I,CN,OH,NH(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C,-C6)haloalkyl,NHCH2(C3-C6)cycloalkyl. Alkyl, NH2, NO2, oxo, (C1-C6)alkyl, (C1-C6)alkyl, (C1-C6c6)alkoxy and C(O)O-(C1-C6)alkyl; and N-oxides, agriculturally acceptable acid-added salts, salt derivatives, solvates, ester derivatives, crystal polymorphs, isotopes, isolated stereoisomers and tautomers of molecules with the formula one2. Molecules according to claim 1 where X3 is chosen from a group consisting of (1) formula, (2) formula, (3) formula, (4) formula, page 6 of 19 pages, (5) formula, (6) formula, (7) formula, (8) formula, (9) formula, (10) formula, (11) formula, page 7 of 19 pages, (12) formula, (13) formula, (14) formula, where: (a) R15 is chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl, (C1-C6) alkinyl, (C1-C6) haloalkyl, (C1-C6) alkyl, (C1-C6) alkoxy,C(=0)(C1-C6)alkyl and (C1-C6)alkoxy C(=O)(C1-C6)alkyl;(b) X4 was chosen from the group consisting of (i) N,(ii) NO and (iii) CR16 where R16 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halosy Colealkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl Page 8 of 19 of 19, in which each alkyl, cycloalkyl, alkynyl, cycloalkinyl, alkynyl, alkoxy, haloalkyl, halocycloalkyl, haloalkinyl, halocycloalkinyl and haloalkoxy may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)alkyl,(C1-C6)calkoxy and C(O)O-(C1-C6)alkyl;(c)Xs were selected from the group consisting of (i)N,(ii)NO and (iii)CR17 where R17 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)calkoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkinil,(C3- C6)halocycloalkenil,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,C(O)O(C1-C6)calkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)halocalkyl-S(O)2NH2;(d) selected from the group consisting of(i) N,(ii) NO and(iii) and CR18. Where R18 was selected from the group consisting of H,F,Cl,Br,I,CN,NO2,OH,NH2,SCN,CHO,(C1-C6)alkyl,(C2-C6)calkinil,(c2-c6)calkinil,(C1-C6)halocalkyl,(C1-C6)alkoxy,(C1-C6)halocalkoxy,NH(C1-C6)alkyl Alkyl,N((C1-C6)alkyl)2,S(C1-C6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl,CONH(C1-C6)alkyl,NHCO(C1-C6)alkyl,N(C1-C6)alkyl-CO(C1-C6)alkyl,NHCO(C2-C6)alkenyl,NHCO(C3-C6)cycloalkyl,NHCO(C1-C6)haloalkyl,N(C1-C6)alkyl-CO(C1-C6)haloalkyl,NHCO(C1-C6)alkylphenyl,NH-C(O)O(C1-C6)alkyl,N(C1-C6)alkyl-C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,phenyl,pyrazolyl,imidazolyl and triazolyl. Page 9 of the dictionary. Nineteen functional groups in which each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, halocycloalkyl, cyclocalkyl, phenyl, imidazolyl, and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, nh2, no2, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(O)O-(C1-C6)alkyl. (e) x7 was selected from a group consisting of (i)N,(ii)NO and (iii)CR19, where R19 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(CC1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,C(O)O(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (f) X8 was chosen from the group consisting of (i)N,(ii) NO and (iii) CR20 where R20 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,N02,(C1-C6 alkyl,(C3-C6)cycloalkyl, (C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloclcoxy,r(C1-C 6) alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,c(o)o(c1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (g) R21 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkenil,(C3-C6)halocycloalkenil,(C1-C6)halocalkenil,S(C1-c6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-c6)calkyl,S(C1-C6) page 10 of 19 pages of haloalkyl,S((O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)calcoxy and C(O)O-(C1-C6)alkyl(h). R22 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloclcoxy. ,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where alkyl,alkenyl,calkinyl,haloalkyl,alkoxy,haloclkoxy,phenyl,Each imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl(i). R23 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6). Halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C 6) Haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl,alkenyl,alkinyl,haloalkyl,alxoxy,haloalxoxy,phenyl,imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alxoxy and C(O)O-(C1-C6)alkyl(j) R24 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkyl,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkene Phenyl, pyridinyl and thienyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6haloalkyl-S(O)2NH2,phenyl, pyridinyl and thienyl Where each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, inidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group comprising F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl3. The molecule under claim 1 where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolyl, oxazolyl, pyrazinil, pyrazolil, pyridazinil, pyridyl, pyrimidinil, tetrazolyl, thiadiazolyl, thiazolyl, thienil, triazinil,[1,2,4] triazolo[1,[5-c]pyrimidinil, triazolil, 2,3-dihydrophthalazine-1,4-dionil, indolinil and pyrimidine-2,4(1H,3H / )-dionil, where the selected representatives were from the group comprising F,Cl,Br,I,H,CN,NH2,NO2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil and (C3-C6)halocycloalkyl4. The molecule according to claim 1, where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolinil, oxazolyl, pyridyl and thiadiazolyl, where such substitute is chosen from the group consisting of F, Cl, Br, I, H, CN, NO2, NH2, (C1-C6) alkoxy, (C1-C6) alkyl, (C1-C6) haloalkoxy, (C1-C6) haloalkyl, (C2-C6) haloalkenyl, (C3-C6) halocycloalkenyl and (C3-C6) halocycloalkyl5. The molecule according to claim 1 where X3 is N(R15)(substituted or unsubstituted phenyl)(a) where such R15fy is chosen from the group containing H and (C1-C6) alkyls(b) where such substituted phenyl has one or more representatives chosen from the group containing F,Cl,Br,I,CN,N02,NH2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6haloalkyl,(C2-C6)haloalkinyl,(C3-C6)cycloalkinyl,(C3-C6)cycloalkyl,(C3-C6)halocycloylkinyl and(C3-C6)halocycloalkyl. Page 12 of 19, page 6. The molecules according to claim 1 are (A) R1, R2, R3, R4, R5, R11 and R12 each freely chosen from the group consisting of H, F, Cl, Br, (C1-C6) alkyl, (C1-C6) haloalkyl and (C1-C6) haloalkoxy; (B) R6 and R9 are H; (C) R7 is chosen from the group consisting of C1 and Br; (D) R8 is chosen from the group consisting of C1 and Br; (E) Q1 and Q2 each freely chosen from the group consisting of O and S; (F) R10 is H; (G) x1 is chosen from the group consisting of; (4) N, (5) NO and (6) CR13 where R13 was chosen from a group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl and triazolyl;(H) x2 was chosen from a group consisting of (I)(3)N and (4). CR14 where R14 was chosen from a group consisting of H,F,C1 and(C1-C6)alkoxy;(I)X3 was chosen from a group consisting of (3)formula,(4)formula,Page 13 of 19 pages R15 where (h) R15 was chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl and (C1-C6) haloalkyl; (i) X4 was chosen from a group consisting of (i) N and (ii) CR16 where R16 was chosen from a group consisting of H, F, Cl, CN, NH2 and (C1-C6) alkyl; (j) Xs was chosen from a group consisting of (iv) N, (v) NO and (vi) CR17 where R17 was chosen from a group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from a group consisting of (iv) N, (v) NO and (vi) and CR18 where R18 was chosen from a group consisting of H, F, Cl, CN, NO2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6)alkyl,(C1-C6)haloalkyl,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,CONH(C1-C6)alkyl andNHCO(C1-C6)alkyl;(I) X7 is CR19 where R19 was chosen from the group consisting of H,NH2 and F; page 14 of 19 pages;(m)X8 is CR20 where R20 was chosen from the group consisting of H,F,Cl,NH2 and (C1-C6)alkyl; and(n)R21,R22,R23 andR24 are H7.molecules according to claim 1 where(A)R1 is H;(B) R2 was chosen from the group consisting of H,Cl,Br,(CrC6)alkyl and (C,-c6)haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C,-C6)alkyl,(C,-c6)haloalkyl and(C1-C6)haloalkoxy;(D) R4 was chosen from the group consisting of H,Cl,Br,(C1-C6)alkyl and(C1-C6)haloalkyl;(E)R5 was chosen from the group consisting of H and C1;(F)R6 is H;(G)R7 was chosen from the group consisting of C1 and Br;(H)R8 was chosen from the group consisting of C1 and Br;(I)R9 is H;(J)Q1 is 0;(K)(Q2 was chosen from the group consisting of O and S;(L)R10 is H;(M) R11 was selected from a group consisting of H,F,C1 and (C1-C6) alkyls; (N)R12 was selected from a group consisting of H and C1; (O)X1 was selected from a group consisting of (1)N,(2)NO and (3)CR13 where R13 was selected from a group consisting of H,F,Cl,Br,I,CN,(C1-C6) alkyls,(C1C6) alkoxy,(C1-C6) haloalkyls,(C1-C6) haloalkyls,S(C1-C6) alkyls,S(O)(C1-C6) alkyls,S(O)2(C1-C6) alkyls and triazolyls; page 15 of 19 pages. (P) X2 was selected from a group consisting of (1) N and (2) CR14, where R14 was chosen from a group consisting of H, F, C1 and (c1-c6) alkoxy; and (Q) X3 was chosen from a group consisting of (3) formulas, (4) formulas,(5) Formula and (6) Formula in which (h) R15 was chosen from the group consisting of H, (C1-C6) alkyl, (C1-C6) alkynyl and (C1-C6) haloalkyl; (i) X4 was chosen from the group consisting of (i) N and (ii) CR16 in which R16 was chosen from the group consisting of H, F, Cl, CN, NH and (C1-C6) alkyl. Page 16 of 19 pages. (j) X5 was chosen from the group consisting of (i) N, (ii) NO and (iii) CR17 in which R17 was chosen from the group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from the group consisting of (i) N, (ii) NO and (iii) (I) X7 is CR19, where R19 was chosen from the group consisting of H, NH2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy, (C1-C6) haloalkoxy, S(C1-C6) alkyl, S(O)(C1-C6) alkyl, S(O)2(C1-C6) alkyl, CONH(C1-C6) alkyl and NHCO(C1-C6) alkyl; (m) X8 is CR20, where R20 was chosen from the group consisting of H, F, Cl, NH2 and (C1-C6) alkyl; and (n) R21, R22, R23 and R24 are H8. The molecule according to claim 1 where:(A) R1 is chosen from a group consisting of H, F or C1;(B) R2 is chosen from a group consisting of H, F, Cl, Br,(C1-C6) alkyl and (C1-C6) haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C1-C6) alkyl,(C1-C6) haloalkyl and (C1-C6) haloalkoxy;(D) R4 was chosen from the group consisting of H,F,Cl,Br,(C1C6) alkyl and (C1-C6) haloalkyl;(E) R5 was chosen from the group consisting of H,F and C1;(F) R6 is H; page 17 of 19 pages;(G) R7 was chosen from the group consisting of C1 and Br;(H) R8 was chosen from the group consisting of C1 and Br;(I) R9 is H;(J) Q1 is O;(K) Q2 was chosen from the group consisting of O and S;(L) R10 is H;(M) R11 (N) R12 is chosen from the group consisting of H and C1; (O) X1 is CR13 where R13 is chosen from the group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; (P) X2 is CR14 where R4 is chosen from the group consisting of H,F,C1 and(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; and (Q) X3 is the formula where R15 is chosen from the group consisting of H,(C1-C6)alkyl,(C2-C6)alkenyl and (C1-C6)haloalkyl; X4 is CR16 where R16 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X5 is CR17 where R17 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X6 is CR18 where R18 .... 2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; page 18 of 19 pages X7 is CR19, where R19 was chosen from the group consisting of H,F,Cl,NH2CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; X8 is CR20, where R20 was chosen from the group consisting of H,F,Cl,CN,NH2NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; 9. A molecule pursuant to claim 1, which is selected from one of the following molecules: F1 to F249, F251 to F255, F257 to F268, F270 to F275, F277 to F320, F322 to F443, F445 to F465, F469, F471 to F488, F490 to F500, F502 to F506, F510, F511, F513 to F520, F524 to F532, F537 to F599.PF1, PF2, PF4 to PF22, PF24 to PF58, PF60, PF62, PF65, PF67 to PF78, PF102, PF104, PF107 to PF110, PF113 to PF119, PF122 to PF127, PF130, PF133 to PF136, PF138 to PF141, PF143, PF152, PF153, PF155, PF156, PF158, PF161 to PF164.

10. A composition consisting of one of the molecules under claims 1 to 9 and a carrier.

11. A process to control the pests, such process consisting of the application at the site with an effective pest-eliminating dose of one of the molecules under claims 1 to 10.

12. The process, which involves the formula 13-113-2, involves the reaction of molecule 13-1 with (C1-C6) alkyl orthoformates in the presence of acids with a pH between 0 and 5. This reaction is carried out in a (C1-C6) alkanol solvent at temperatures ranging from 0°C to ambient temperature and under ambient pressure to form molecule 13-2, in which R1, R2, R3, R4, R5,R6 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

13. The process, which includes page 19 of the formula b, formula 13-213-3, causes 13-2 to react with a carbine source such as haloform in the presence of an inorganic alkali and a phase-transfer catalyst at temperatures from approximately ambient temperature down to below the boiling point of haloform to form 13-3 molecules in which R1, R2, R3, R4, R5, R6, R5, R7, R8 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

14. The process comprising formula c13-313-4 involves the conversion of cyclopropyl acetal 13-3 to the aldehyde 13-4 in a polar solvent in the presence of an aqueous mineral acid at ambient temperature where R1, R2, R3, R4, R5, R6, R5, R7, R8, and R9 satisfy claim 115. The process comprising formula d13-41-3 involves the oxidation of 13-4 in a polar aprotic solvent at temperatures ranging from approximately 0°C to approximately ambient temperature where R1, R2, R3, R4, Rs, R6, R7, R8, and R9 satisfy claim 115.R8 and R9 comply with claim 1------------------07 / 04 / 2016------(OCR)Page 1 of 19 pages. Claim 1. A molecule with the following formula in which:(A) R1 is chosen from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)calkyl,(C3-C6)cycloalkyl,(C2-C6)alkenyl,(C3C€6)cyclocalkenyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C,-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl L,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(0)(C1-C6)alkyl,S(0)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(B) R2 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkinil, (C3-C6) cycloalkinil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalky]-S(O)2NH2;(C)R3 were selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocyclocalkyl,(C2-C6)halocalkenil,(C3-C6)H Halocyclocalcinyl,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)halocalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,(C1-C6)calkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; Page 2 of 19 (D) R4 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkenil, (C3-C6) cycloalkenil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) halocycloalkyl, (C2-C6) haloalkinine. L,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(E) R5 was selected from the group containing H,F,Cl,Br,I,CN,NH2,N02,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,C(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil ,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(F) R6 was selected from the group containing H and (C1-C6) alkyls;(G) R7 was selected from the group containing H, F, Cl, Br and I;(H) R8 was selected from the group containing F, Cl, Br and I;(I) R9 was selected from the group containing H and (C1-C6) alkyls;(J) Q1 was selected from the group containing O and r;(K) Q2 was selected from the group containing O and r;(L) R10 was selected from the group containing H, (C1-C6) alkyls, (C2-C6) alkenyls, (C1-C6) haloalkyls, (C1-C6) alkyls, (C1-C6) alkoxys, C(=0)(C1-C6) alkyls and (C1-C6) alkoxys C(=0)(C1-C6) alkyls;(M) R11 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl.(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2; Page 3 of 19 pages (N) R12 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)alkoxy,(CrC6)haloalkyl,(C3-C6)haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl, (C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalkyl-S(O)2NH2;(O) X1 was selected from the group consisting of (7)N,(8)NO and (9)CR13 where R13 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2 and triazolyl;(P) X2 was selected from a group consisting of (7)N,(8)NO and (9)CR14, where R14 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl. Page 4 of 19(Q) X3 was selected from the group consisting of N(RIS)(replaced or unreplaced phenyls),N(R15)(substituted or unsubstituted heterocyclyls) and substituted or unsubstituted heterocyclyls(a) where such R15 is selected from a group consisting of H,(C1-C6)alkyl,(C2-c6)alkinyl,(C2-C6)alkinyl,(C1-C6)haloalkyl,(C1-C6)alkyl(C1-C6)alkoxy,C(=0)(C1-C6)alkyl and(C1-C6)alkoxyC(=0)(C1-C6)alkyl(b). where such substituted phenyls and substituted heterocyclyls with one or more substitutes selected from the group consisting of F,Cl,Br,I,H,CN,CHO,NHOH,NO,NO2,OH,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)alkylphenyl,(C1-C6)alkyl-S(0)2NH2,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkyl-S(O)2NH2,(C2-C6)alkinyl,(C2-C6)alkinyl ,(C2-C6)haloalkenil,(C3-C6)cycloalkenil,(C3-C6)cycloalkyl,(C3-C6)halocycloalkenil,(C3-C6)halocycloalkyl,(C1-C6)alkyl((C1-C6)alkyl)(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,C(O)(C1-C6)alkyl,C(O)NH(C1-C6)alkyl,C(O)NHphenyl,C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),imidazolyl,N((C1-C6)alkyl)(C(O)(C1-C6)alkyl),N((C1-C6)alkyl)(C(O)(C1-C6)alkyl-O(C1-C6)alkyl),N((C1-C6)alkyl)(C(0)(C1-C6)haloalkyl),N((C1-C6)alkyl)(C(O)O(C1-C6)alkyl),N((C1-C6)alkyl)2,N(C(O)O(C1-C6)alkyl)2,N=CH-phenyl,NH((C1-C6)alkylC(O)(C1-C6)alkyl),NH(C(0)(C1-C6)alkyl) ,NH(C(O)(C2-C6)alkinyl),NH(C(O)(C3-C6)cycloalkyl),NH(C1-C6)alkyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl1NH(CrC6)alkylphenyl,NH(S(O)2(C1-C6)alkyl),NH2,NHC(O)(C1-C6)alkyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)halo Alkyl,NHC(O)(C1-C6)alkinyl,NH-C(O)O(C1-C6)alkyl,oxazolyl,phenyl,pyrazolyl,pyridinyl,S(=NCN)((C1-C6)alkyl),S(C1-C6)alkyl,r(C1-C6)haloalkyl,S(O)(=NCN)((C1-C6)alkyl),S(O)(C1-C6)alkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)alkyl,S(O)2( C1-C6) Haloalkyl, SCN, Thiazolyl, Thienyl and Triazolyl, where alkoxy, alkyl, haloalkoxy, haloalkyl, alkenyl, alkinyl, haloalkenyl, cycloalkenyl, cycloalkyl, halocycloalkenyl, halocycloalkyl, imidazoyl, phenyl, pyrazolyl, pyridinyl, thiazoyl.Each thienyl and triazolyl may be alternatively replaced by one or more substitutes selected from the group consisting of F,Cl,Br,I,CN,OH,NH(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C,-C6)haloalkyl,NHCH2(C3-C6)cycloalkyl. Alkyl, NH2, NO2, oxo, (C1-C6)alkyl, (C1-C6)alkyl, (C1-C6c6)alkoxy and C(O)O-(C1-C6)alkyl; and N-oxides, agriculturally acceptable acid-added salts, salt derivatives, solvates, ester derivatives, crystal polymorphs, isotopes, isolated stereoisomers and tautomers of molecules with the formula one2. Molecules according to claim 1 where X3 is chosen from a group consisting of (1) formula, (2) formula, (3) formula, (4) formula, page 6 of 19 pages, (5) formula, (6) formula, (7) formula, (8) formula, (9) formula, (10) formula, (11) formula, page 7 of 19 pages, (12) formula, (13) formula, (14) formula, where: (a) R15 is chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl, (C1-C6) alkinyl, (C1-C6) haloalkyl, (C1-C6) alkyl, (C1-C6) alkoxy,C(=0)(C1-C6)alkyl and (C1-C6)alkoxy C(=O)(C1-C6)alkyl;(b) X4 was chosen from the group consisting of (i) N,(ii) NO and (iii) CR16 where R16 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halosy Colealkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl Page 8 of 19 of 19, in which each alkyl, cycloalkyl, alkynyl, cycloalkinyl, alkynyl, alkoxy, haloalkyl, halocycloalkyl, haloalkinyl, halocycloalkinyl and haloalkoxy may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)alkyl,(C1-C6)calkoxy and C(O)O-(C1-C6)alkyl;(c)Xs were selected from the group consisting of (i)N,(ii)NO and (iii)CR17 where R17 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)calkoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkinil,(C3- C6)halocycloalkenil,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,C(O)O(C1-C6)calkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)halocalkyl-S(O)2NH2;(d) selected from the group consisting of(i) N,(ii) NO and(iii) and CR18. Where R18 was selected from the group consisting of H,F,Cl,Br,I,CN,NO2,OH,NH2,SCN,CHO,(C1-C6)alkyl,(C2-C6)calkinil,(c2-c6)calkinil,(C1-C6)halocalkyl,(C1-C6)alkoxy,(C1-C6)halocalkoxy,NH(C1-C6)alkyl Alkyl,N((C1-C6)alkyl)2,S(C1-C6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl,CONH(C1-C6)alkyl,NHCO(C1-C6)alkyl,N(C1-C6)alkyl-CO(C1-C6)alkyl,NHCO(C2-C6)alkenyl,NHCO(C3-C6)cycloalkyl,NHCO(C1-C6)haloalkyl,N(C1-C6)alkyl-CO(C1-C6)haloalkyl,NHCO(C1-C6)alkylphenyl,NH-C(O)O(C1-C6)alkyl,N(C1-C6)alkyl-C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,phenyl,pyrazolyl,imidazolyl and triazolyl. Page 9 of the dictionary. Nineteen functional groups in which each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, halocycloalkyl, cyclocalkyl, phenyl, imidazolyl, and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, nh2, no2, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(O)O-(C1-C6)alkyl. (e) x7 was selected from a group consisting of (i)N,(ii)NO and (iii)CR19, where R19 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(CC1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,C(O)O(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (f) X8 was chosen from the group consisting of (i)N,(ii) NO and (iii) CR20 where R20 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,N02,(C1-C6 alkyl,(C3-C6)cycloalkyl, (C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloclcoxy,r(C1-C 6) alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,c(o)o(c1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (g) R21 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkenil,(C3-C6)halocycloalkenil,(C1-C6)halocalkenil,S(C1-c6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-c6)calkyl,S(C1-C6) page 10 of 19 pages of haloalkyl,S((O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)calcoxy and C(O)O-(C1-C6)alkyl(h). R22 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloclcoxy. ,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where alkyl,alkenyl,calkinyl,haloalkyl,alkoxy,haloclkoxy,phenyl,Each imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl(i). R23 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6). Halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C 6) Haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl,alkenyl,alkinyl,haloalkyl,alxoxy,haloalxoxy,phenyl,imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alxoxy and C(O)O-(C1-C6)alkyl(j) R24 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkyl,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkene Phenyl, pyridinyl and thienyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6haloalkyl-S(O)2NH2,phenyl, pyridinyl and thienyl Where each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, inidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group comprising F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl3. The molecule under claim 1 where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolyl, oxazolyl, pyrazinil, pyrazolil, pyridazinil, pyridyl, pyrimidinil, tetrazolyl, thiadiazolyl, thiazolyl, thienil, triazinil,[1,2,4] triazolo[1,[5-c]pyrimidinil, triazolil, 2,3-dihydrophthalazine-1,4-dionil, indolinil and pyrimidine-2,4(1H,3H / )-dionil, where the selected representatives were from the group comprising F,Cl,Br,I,H,CN,NH2,NO2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil and (C3-C6)halocycloalkyl4. The molecule according to claim 1, where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolinil, oxazolyl, pyridyl and thiadiazolyl, where such substitute is chosen from the group consisting of F, Cl, Br, I, H, CN, NO2, NH2, (C1-C6) alkoxy, (C1-C6) alkyl, (C1-C6) haloalkoxy, (C1-C6) haloalkyl, (C2-C6) haloalkenyl, (C3-C6) halocycloalkenyl and (C3-C6) halocycloalkyl5. The molecule according to claim 1 where X3 is N(R15)(substituted or unsubstituted phenyl)(a) where such R15fy is chosen from the group containing H and (C1-C6) alkyls(b) where such substituted phenyl has one or more representatives chosen from the group containing F,Cl,Br,I,CN,N02,NH2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6haloalkyl,(C2-C6)haloalkinyl,(C3-C6)cycloalkinyl,(C3-C6)cycloalkyl,(C3-C6)halocycloylkinyl and(C3-C6)halocycloalkyl. Page 12 of 19, page 6. The molecules according to claim 1 are (A) R1, R2, R3, R4, R5, R11 and R12 each freely chosen from the group consisting of H, F, Cl, Br, (C1-C6) alkyl, (C1-C6) haloalkyl and (C1-C6) haloalkoxy; (B) R6 and R9 are H; (C) R7 is chosen from the group consisting of C1 and Br; (D) R8 is chosen from the group consisting of C1 and Br; (E) Q1 and Q2 each freely chosen from the group consisting of O and S; (F) R10 is H; (G) x1 is chosen from the group consisting of; (4) N, (5) NO and (6) CR13 where R13 was chosen from a group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl and triazolyl;(H) x2 was chosen from a group consisting of (I)(3)N and (4). CR14 where R14 was chosen from a group consisting of H,F,C1 and(C1-C6)alkoxy;(I)X3 was chosen from a group consisting of (3)formula,(4)formula,Page 13 of 19 pages R15 where (h) R15 was chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl and (C1-C6) haloalkyl; (i) X4 was chosen from a group consisting of (i) N and (ii) CR16 where R16 was chosen from a group consisting of H, F, Cl, CN, NH2 and (C1-C6) alkyl; (j) Xs was chosen from a group consisting of (iv) N, (v) NO and (vi) CR17 where R17 was chosen from a group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from a group consisting of (iv) N, (v) NO and (vi) and CR18 where R18 was chosen from a group consisting of H, F, Cl, CN, NO2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6)alkyl,(C1-C6)haloalkyl,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,CONH(C1-C6)alkyl andNHCO(C1-C6)alkyl;(I) X7 is CR19 where R19 was chosen from the group consisting of H,NH2 and F; page 14 of 19 pages;(m)X8 is CR20 where R20 was chosen from the group consisting of H,F,Cl,NH2 and (C1-C6)alkyl; and(n)R21,R22,R23 andR24 are H7.molecules according to claim 1 where(A)R1 is H;(B) R2 was chosen from the group consisting of H,Cl,Br,(CrC6)alkyl and (C,-c6)haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C,-C6)alkyl,(C,-c6)haloalkyl and(C1-C6)haloalkoxy;(D) R4 was chosen from the group consisting of H,Cl,Br,(C1-C6)alkyl and(C1-C6)haloalkyl;(E)R5 was chosen from the group consisting of H and C1;(F)R6 is H;(G)R7 was chosen from the group consisting of C1 and Br;(H)R8 was chosen from the group consisting of C1 and Br;(I)R9 is H;(J)Q1 is 0;(K)(Q2 was chosen from the group consisting of O and S;(L)R10 is H;(M) R11 was selected from a group consisting of H,F,C1 and (C1-C6) alkyls; (N)R12 was selected from a group consisting of H and C1; (O)X1 was selected from a group consisting of (1)N,(2)NO and (3)CR13 where R13 was selected from a group consisting of H,F,Cl,Br,I,CN,(C1-C6) alkyls,(C1C6) alkoxy,(C1-C6) haloalkyls,(C1-C6) haloalkyls,S(C1-C6) alkyls,S(O)(C1-C6) alkyls,S(O)2(C1-C6) alkyls and triazolyls; page 15 of 19 pages. (P) X2 was selected from a group consisting of (1) N and (2) CR14, where R14 was chosen from a group consisting of H, F, C1 and (c1-c6) alkoxy; and (Q) X3 was chosen from a group consisting of (3) formulas, (4) formulas,(5) Formula and (6) Formula in which (h) R15 was chosen from the group consisting of H, (C1-C6) alkyl, (C1-C6) alkynyl and (C1-C6) haloalkyl; (i) X4 was chosen from the group consisting of (i) N and (ii) CR16 in which R16 was chosen from the group consisting of H, F, Cl, CN, NH and (C1-C6) alkyl. Page 16 of 19 pages. (j) X5 was chosen from the group consisting of (i) N, (ii) NO and (iii) CR17 in which R17 was chosen from the group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from the group consisting of (i) N, (ii) NO and (iii) (I) X7 is CR19, where R19 was chosen from the group consisting of H, NH2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy, (C1-C6) haloalkoxy, S(C1-C6) alkyl, S(O)(C1-C6) alkyl, S(O)2(C1-C6) alkyl, CONH(C1-C6) alkyl and NHCO(C1-C6) alkyl; (m) X8 is CR20, where R20 was chosen from the group consisting of H, F, Cl, NH2 and (C1-C6) alkyl; and (n) R21, R22, R23 and R24 are H8. The molecule according to claim 1 where:(A) R1 is chosen from a group consisting of H, F or C1;(B) R2 is chosen from a group consisting of H, F, Cl, Br,(C1-C6) alkyl and (C1-C6) haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C1-C6) alkyl,(C1-C6) haloalkyl and (C1-C6) haloalkoxy;(D) R4 was chosen from the group consisting of H,F,Cl,Br,(C1C6) alkyl and (C1-C6) haloalkyl;(E) R5 was chosen from the group consisting of H,F and C1;(F) R6 is H; page 17 of 19 pages;(G) R7 was chosen from the group consisting of C1 and Br;(H) R8 was chosen from the group consisting of C1 and Br;(I) R9 is H;(J) Q1 is O;(K) Q2 was chosen from the group consisting of O and S;(L) R10 is H;(M) R11 (N) R12 is chosen from the group consisting of H and C1; (O) X1 is CR13 where R13 is chosen from the group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; (P) X2 is CR14 where R4 is chosen from the group consisting of H,F,C1 and(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; and (Q) X3 is the formula where R15 is chosen from the group consisting of H,(C1-C6)alkyl,(C2-C6)alkenyl and (C1-C6)haloalkyl; X4 is CR16 where R16 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X5 is CR17 where R17 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X6 is CR18 where R18 .... 2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; page 18 of 19 pages X7 is CR19, where R19 was chosen from the group consisting of H,F,Cl,NH2CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; X8 is CR20, where R20 was chosen from the group consisting of H,F,Cl,CN,NH2NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; 9. A molecule pursuant to claim 1, which is selected from one of the following molecules: F1 to F249, F251 to F255, F257 to F268, F270 to F275, F277 to F320, F322 to F443, F445 to F465, F469, F471 to F488, F490 to F500, F502 to F506, F510, F511, F513 to F520, F524 to F532, F537 to F599.PF1, PF2, PF4 to PF22, PF24 to PF58, PF60, PF62, PF65, PF67 to PF78, PF102, PF104, PF107 to PF110, PF113 to PF119, PF122 to PF127, PF130, PF133 to PF136, PF138 to PF141, PF143, PF152, PF153, PF155, PF156, PF158, PF161 to PF164.

10. A composition consisting of one of the molecules under claims 1 to 9 and a carrier.

11. A process to control the pests, such process consisting of the application at the site with an effective pest-eliminating dose of one of the molecules under claims 1 to 10.

12. The process, which involves the formula 13-113-2, involves the reaction of molecule 13-1 with (C1-C6) alkyl orthoformates in the presence of acids with a pH between 0 and 5. This reaction is carried out in a (C1-C6) alkanol solvent at temperatures ranging from 0°C to ambient temperature and under ambient pressure to form molecule 13-2, in which R1, R2, R3, R4, R5,R6 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

13. The process, which includes page 19 of the formula b, formula 13-213-3, causes 13-2 to react with a carbine source such as haloform in the presence of an inorganic alkali and a phase-transfer catalyst at temperatures from approximately ambient temperature down to below the boiling point of haloform to form 13-3 molecules in which R1, R2, R3, R4, R5, R6, R5, R7, R8 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

14. The process comprising formula c13-313-4 involves the conversion of cyclopropyl acetal 13-3 to the aldehyde 13-4 in a polar solvent in the presence of an aqueous mineral acid at ambient temperature where R1, R2, R3, R4, R5, R6, R5, R7, R8, and R9 satisfy claim 115. The process comprising formula d13-41-3 involves the oxidation of 13-4 in a polar aprotic solvent at temperatures ranging from approximately 0°C to approximately ambient temperature where R1, R2, R3, R4, Rs, R6, R7, R8, and R9 satisfy claim 115.R8 and R9 comply with claim 1------------------07 / 04 / 2016------(OCR)Page 1 of 19 pages. Claim 1. A molecule with the following formula in which:(A) R1 is chosen from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)calkyl,(C3-C6)cycloalkyl,(C2-C6)alkenyl,(C3C€6)cyclocalkenyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C,-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl L,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(0)(C1-C6)alkyl,S(0)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(B) R2 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkinil, (C3-C6) cycloalkinil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalky]-S(O)2NH2;(C)R3 were selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocyclocalkyl,(C2-C6)halocalkenil,(C3-C6)H Halocyclocalcinyl,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)halocalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,(C1-C6)calkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; Page 2 of 19 (D) R4 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkenil, (C3-C6) cycloalkenil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) halocycloalkyl, (C2-C6) haloalkinine. L,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(E) R5 was selected from the group containing H,F,Cl,Br,I,CN,NH2,N02,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,C(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil ,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(F) R6 was selected from the group containing H and (C1-C6) alkyls;(G) R7 was selected from the group containing H, F, Cl, Br and I;(H) R8 was selected from the group containing F, Cl, Br and I;(I) R9 was selected from the group containing H and (C1-C6) alkyls;(J) Q1 was selected from the group containing O and r;(K) Q2 was selected from the group containing O and r;(L) R10 was selected from the group containing H, (C1-C6) alkyls, (C2-C6) alkenyls, (C1-C6) haloalkyls, (C1-C6) alkyls, (C1-C6) alkoxys, C(=0)(C1-C6) alkyls and (C1-C6) alkoxys C(=0)(C1-C6) alkyls;(M) R11 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl.(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2; Page 3 of 19 pages (N) R12 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)alkoxy,(CrC6)haloalkyl,(C3-C6)haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl, (C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalkyl-S(O)2NH2;(O) X1 was selected from the group consisting of (7)N,(8)NO and (9)CR13 where R13 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2 and triazolyl;(P) X2 was selected from a group consisting of (7)N,(8)NO and (9)CR14, where R14 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl. Page 4 of 19(Q) X3 was selected from the group consisting of N(RIS)(replaced or unreplaced phenyls),N(R15)(substituted or unsubstituted heterocyclyls) and substituted or unsubstituted heterocyclyls(a) where such R15 is selected from a group consisting of H,(C1-C6)alkyl,(C2-c6)alkinyl,(C2-C6)alkinyl,(C1-C6)haloalkyl,(C1-C6)alkyl(C1-C6)alkoxy,C(=0)(C1-C6)alkyl and(C1-C6)alkoxyC(=0)(C1-C6)alkyl(b). where such substituted phenyls and substituted heterocyclyls with one or more substitutes selected from the group consisting of F,Cl,Br,I,H,CN,CHO,NHOH,NO,NO2,OH,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)alkylphenyl,(C1-C6)alkyl-S(0)2NH2,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkyl-S(O)2NH2,(C2-C6)alkinyl,(C2-C6)alkinyl ,(C2-C6)haloalkenil,(C3-C6)cycloalkenil,(C3-C6)cycloalkyl,(C3-C6)halocycloalkenil,(C3-C6)halocycloalkyl,(C1-C6)alkyl((C1-C6)alkyl)(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,C(O)(C1-C6)alkyl,C(O)NH(C1-C6)alkyl,C(O)NHphenyl,C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),imidazolyl,N((C1-C6)alkyl)(C(O)(C1-C6)alkyl),N((C1-C6)alkyl)(C(O)(C1-C6)alkyl-O(C1-C6)alkyl),N((C1-C6)alkyl)(C(0)(C1-C6)haloalkyl),N((C1-C6)alkyl)(C(O)O(C1-C6)alkyl),N((C1-C6)alkyl)2,N(C(O)O(C1-C6)alkyl)2,N=CH-phenyl,NH((C1-C6)alkylC(O)(C1-C6)alkyl),NH(C(0)(C1-C6)alkyl) ,NH(C(O)(C2-C6)alkinyl),NH(C(O)(C3-C6)cycloalkyl),NH(C1-C6)alkyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl1NH(CrC6)alkylphenyl,NH(S(O)2(C1-C6)alkyl),NH2,NHC(O)(C1-C6)alkyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)halo Alkyl,NHC(O)(C1-C6)alkinyl,NH-C(O)O(C1-C6)alkyl,oxazolyl,phenyl,pyrazolyl,pyridinyl,S(=NCN)((C1-C6)alkyl),S(C1-C6)alkyl,r(C1-C6)haloalkyl,S(O)(=NCN)((C1-C6)alkyl),S(O)(C1-C6)alkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)alkyl,S(O)2( C1-C6) Haloalkyl, SCN, Thiazolyl, Thienyl and Triazolyl, where alkoxy, alkyl, haloalkoxy, haloalkyl, alkenyl, alkinyl, haloalkenyl, cycloalkenyl, cycloalkyl, halocycloalkenyl, halocycloalkyl, imidazoyl, phenyl, pyrazolyl, pyridinyl, thiazoyl.Each thienyl and triazolyl may be alternatively replaced by one or more substitutes selected from the group consisting of F,Cl,Br,I,CN,OH,NH(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C,-C6)haloalkyl,NHCH2(C3-C6)cycloalkyl. Alkyl, NH2, NO2, oxo, (C1-C6)alkyl, (C1-C6)alkyl, (C1-C6c6)alkoxy and C(O)O-(C1-C6)alkyl; and N-oxides, agriculturally acceptable acid-added salts, salt derivatives, solvates, ester derivatives, crystal polymorphs, isotopes, isolated stereoisomers and tautomers of molecules with the formula one2. Molecules according to claim 1 where X3 is chosen from a group consisting of (1) formula, (2) formula, (3) formula, (4) formula, page 6 of 19 pages, (5) formula, (6) formula, (7) formula, (8) formula, (9) formula, (10) formula, (11) formula, page 7 of 19 pages, (12) formula, (13) formula, (14) formula, where: (a) R15 is chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl, (C1-C6) alkinyl, (C1-C6) haloalkyl, (C1-C6) alkyl, (C1-C6) alkoxy,C(=0)(C1-C6)alkyl and (C1-C6)alkoxy C(=O)(C1-C6)alkyl;(b) X4 was chosen from the group consisting of (i) N,(ii) NO and (iii) CR16 where R16 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halosy Colealkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl Page 8 of 19 of 19, in which each alkyl, cycloalkyl, alkynyl, cycloalkinyl, alkynyl, alkoxy, haloalkyl, halocycloalkyl, haloalkinyl, halocycloalkinyl and haloalkoxy may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)alkyl,(C1-C6)calkoxy and C(O)O-(C1-C6)alkyl;(c)Xs were selected from the group consisting of (i)N,(ii)NO and (iii)CR17 where R17 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)calkoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkinil,(C3- C6)halocycloalkenil,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,C(O)O(C1-C6)calkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)halocalkyl-S(O)2NH2;(d) selected from the group consisting of(i) N,(ii) NO and(iii) and CR18. Where R18 was selected from the group consisting of H,F,Cl,Br,I,CN,NO2,OH,NH2,SCN,CHO,(C1-C6)alkyl,(C2-C6)calkinil,(c2-c6)calkinil,(C1-C6)halocalkyl,(C1-C6)alkoxy,(C1-C6)halocalkoxy,NH(C1-C6)alkyl Alkyl,N((C1-C6)alkyl)2,S(C1-C6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl,CONH(C1-C6)alkyl,NHCO(C1-C6)alkyl,N(C1-C6)alkyl-CO(C1-C6)alkyl,NHCO(C2-C6)alkenyl,NHCO(C3-C6)cycloalkyl,NHCO(C1-C6)haloalkyl,N(C1-C6)alkyl-CO(C1-C6)haloalkyl,NHCO(C1-C6)alkylphenyl,NH-C(O)O(C1-C6)alkyl,N(C1-C6)alkyl-C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,phenyl,pyrazolyl,imidazolyl and triazolyl. Page 9 of the dictionary. Nineteen functional groups in which each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, halocycloalkyl, cyclocalkyl, phenyl, imidazolyl, and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, nh2, no2, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(O)O-(C1-C6)alkyl. (e) x7 was selected from a group consisting of (i)N,(ii)NO and (iii)CR19, where R19 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(CC1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,C(O)O(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (f) X8 was chosen from the group consisting of (i)N,(ii) NO and (iii) CR20 where R20 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,N02,(C1-C6 alkyl,(C3-C6)cycloalkyl, (C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloclcoxy,r(C1-C 6) alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,c(o)o(c1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (g) R21 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkenil,(C3-C6)halocycloalkenil,(C1-C6)halocalkenil,S(C1-c6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-c6)calkyl,S(C1-C6) page 10 of 19 pages of haloalkyl,S((O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)calcoxy and C(O)O-(C1-C6)alkyl(h). R22 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloclcoxy. ,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where alkyl,alkenyl,calkinyl,haloalkyl,alkoxy,haloclkoxy,phenyl,Each imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl(i). R23 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6). Halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C 6) Haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl,alkenyl,alkinyl,haloalkyl,alxoxy,haloalxoxy,phenyl,imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alxoxy and C(O)O-(C1-C6)alkyl(j) R24 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkyl,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkene Phenyl, pyridinyl and thienyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6haloalkyl-S(O)2NH2,phenyl, pyridinyl and thienyl Where each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, inidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group comprising F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl3. The molecule under claim 1 where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolyl, oxazolyl, pyrazinil, pyrazolil, pyridazinil, pyridyl, pyrimidinil, tetrazolyl, thiadiazolyl, thiazolyl, thienil, triazinil,[1,2,4] triazolo[1,[5-c]pyrimidinil, triazolil, 2,3-dihydrophthalazine-1,4-dionil, indolinil and pyrimidine-2,4(1H,3H / )-dionil, where the selected representatives were from the group comprising F,Cl,Br,I,H,CN,NH2,NO2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil and (C3-C6)halocycloalkyl4. The molecule according to claim 1, where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolinil, oxazolyl, pyridyl and thiadiazolyl, where such substitute is chosen from the group consisting of F, Cl, Br, I, H, CN, NO2, NH2, (C1-C6) alkoxy, (C1-C6) alkyl, (C1-C6) haloalkoxy, (C1-C6) haloalkyl, (C2-C6) haloalkenyl, (C3-C6) halocycloalkenyl and (C3-C6) halocycloalkyl5. The molecule according to claim 1 where X3 is N(R15)(substituted or unsubstituted phenyl)(a) where such R15fy is chosen from the group containing H and (C1-C6) alkyls(b) where such substituted phenyl has one or more representatives chosen from the group containing F,Cl,Br,I,CN,N02,NH2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6haloalkyl,(C2-C6)haloalkinyl,(C3-C6)cycloalkinyl,(C3-C6)cycloalkyl,(C3-C6)halocycloylkinyl and(C3-C6)halocycloalkyl. Page 12 of 19, page 6. The molecules according to claim 1 are (A) R1, R2, R3, R4, R5, R11 and R12 each freely chosen from the group consisting of H, F, Cl, Br, (C1-C6) alkyl, (C1-C6) haloalkyl and (C1-C6) haloalkoxy; (B) R6 and R9 are H; (C) R7 is chosen from the group consisting of C1 and Br; (D) R8 is chosen from the group consisting of C1 and Br; (E) Q1 and Q2 each freely chosen from the group consisting of O and S; (F) R10 is H; (G) x1 is chosen from the group consisting of; (4) N, (5) NO and (6) CR13 where R13 was chosen from a group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl and triazolyl;(H) x2 was chosen from a group consisting of (I)(3)N and (4). CR14 where R14 was chosen from a group consisting of H,F,C1 and(C1-C6)alkoxy;(I)X3 was chosen from a group consisting of (3)formula,(4)formula,Page 13 of 19 pages R15 where (h) R15 was chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl and (C1-C6) haloalkyl; (i) X4 was chosen from a group consisting of (i) N and (ii) CR16 where R16 was chosen from a group consisting of H, F, Cl, CN, NH2 and (C1-C6) alkyl; (j) Xs was chosen from a group consisting of (iv) N, (v) NO and (vi) CR17 where R17 was chosen from a group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from a group consisting of (iv) N, (v) NO and (vi) and CR18 where R18 was chosen from a group consisting of H, F, Cl, CN, NO2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6)alkyl,(C1-C6)haloalkyl,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,CONH(C1-C6)alkyl andNHCO(C1-C6)alkyl;(I) X7 is CR19 where R19 was chosen from the group consisting of H,NH2 and F; page 14 of 19 pages;(m)X8 is CR20 where R20 was chosen from the group consisting of H,F,Cl,NH2 and (C1-C6)alkyl; and(n)R21,R22,R23 andR24 are H7.molecules according to claim 1 where(A)R1 is H;(B) R2 was chosen from the group consisting of H,Cl,Br,(CrC6)alkyl and (C,-c6)haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C,-C6)alkyl,(C,-c6)haloalkyl and(C1-C6)haloalkoxy;(D) R4 was chosen from the group consisting of H,Cl,Br,(C1-C6)alkyl and(C1-C6)haloalkyl;(E)R5 was chosen from the group consisting of H and C1;(F)R6 is H;(G)R7 was chosen from the group consisting of C1 and Br;(H)R8 was chosen from the group consisting of C1 and Br;(I)R9 is H;(J)Q1 is 0;(K)(Q2 was chosen from the group consisting of O and S;(L)R10 is H;(M) R11 was selected from a group consisting of H,F,C1 and (C1-C6) alkyls; (N)R12 was selected from a group consisting of H and C1; (O)X1 was selected from a group consisting of (1)N,(2)NO and (3)CR13 where R13 was selected from a group consisting of H,F,Cl,Br,I,CN,(C1-C6) alkyls,(C1C6) alkoxy,(C1-C6) haloalkyls,(C1-C6) haloalkyls,S(C1-C6) alkyls,S(O)(C1-C6) alkyls,S(O)2(C1-C6) alkyls and triazolyls; page 15 of 19 pages. (P) X2 was selected from a group consisting of (1) N and (2) CR14, where R14 was chosen from a group consisting of H, F, C1 and (c1-c6) alkoxy; and (Q) X3 was chosen from a group consisting of (3) formulas, (4) formulas,(5) Formula and (6) Formula in which (h) R15 was chosen from the group consisting of H, (C1-C6) alkyl, (C1-C6) alkynyl and (C1-C6) haloalkyl; (i) X4 was chosen from the group consisting of (i) N and (ii) CR16 in which R16 was chosen from the group consisting of H, F, Cl, CN, NH and (C1-C6) alkyl. Page 16 of 19 pages. (j) X5 was chosen from the group consisting of (i) N, (ii) NO and (iii) CR17 in which R17 was chosen from the group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from the group consisting of (i) N, (ii) NO and (iii) (I) X7 is CR19, where R19 was chosen from the group consisting of H, NH2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy, (C1-C6) haloalkoxy, S(C1-C6) alkyl, S(O)(C1-C6) alkyl, S(O)2(C1-C6) alkyl, CONH(C1-C6) alkyl and NHCO(C1-C6) alkyl; (m) X8 is CR20, where R20 was chosen from the group consisting of H, F, Cl, NH2 and (C1-C6) alkyl; and (n) R21, R22, R23 and R24 are H8. The molecule according to claim 1 where:(A) R1 is chosen from a group consisting of H, F or C1;(B) R2 is chosen from a group consisting of H, F, Cl, Br,(C1-C6) alkyl and (C1-C6) haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C1-C6) alkyl,(C1-C6) haloalkyl and (C1-C6) haloalkoxy;(D) R4 was chosen from the group consisting of H,F,Cl,Br,(C1C6) alkyl and (C1-C6) haloalkyl;(E) R5 was chosen from the group consisting of H,F and C1;(F) R6 is H; page 17 of 19 pages;(G) R7 was chosen from the group consisting of C1 and Br;(H) R8 was chosen from the group consisting of C1 and Br;(I) R9 is H;(J) Q1 is O;(K) Q2 was chosen from the group consisting of O and S;(L) R10 is H;(M) R11 (N) R12 is chosen from the group consisting of H and C1; (O) X1 is CR13 where R13 is chosen from the group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; (P) X2 is CR14 where R4 is chosen from the group consisting of H,F,C1 and(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; and (Q) X3 is the formula where R15 is chosen from the group consisting of H,(C1-C6)alkyl,(C2-C6)alkenyl and (C1-C6)haloalkyl; X4 is CR16 where R16 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X5 is CR17 where R17 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X6 is CR18 where R18 .... 2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; page 18 of 19 pages X7 is CR19, where R19 was chosen from the group consisting of H,F,Cl,NH2CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; X8 is CR20, where R20 was chosen from the group consisting of H,F,Cl,CN,NH2NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; 9. A molecule pursuant to claim 1, which is selected from one of the following molecules: F1 to F249, F251 to F255, F257 to F268, F270 to F275, F277 to F320, F322 to F443, F445 to F465, F469, F471 to F488, F490 to F500, F502 to F506, F510, F511, F513 to F520, F524 to F532, F537 to F599.PF1, PF2, PF4 to PF22, PF24 to PF58, PF60, PF62, PF65, PF67 to PF78, PF102, PF104, PF107 to PF110, PF113 to PF119, PF122 to PF127, PF130, PF133 to PF136, PF138 to PF141, PF143, PF152, PF153, PF155, PF156, PF158, PF161 to PF164.

10. A composition consisting of one of the molecules under claims 1 to 9 and a carrier.

11. A process to control the pests, such process consisting of the application at the site with an effective pest-eliminating dose of one of the molecules under claims 1 to 10.

12. The process, which involves the formula 13-113-2, involves the reaction of molecule 13-1 with (C1-C6) alkyl orthoformates in the presence of acids with a pH between 0 and 5. This reaction is carried out in a (C1-C6) alkanol solvent at temperatures ranging from 0°C to ambient temperature and under ambient pressure to form molecule 13-2, in which R1, R2, R3, R4, R5,R6 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

13. The process, which includes page 19 of the formula b, formula 13-213-3, causes 13-2 to react with a carbine source such as haloform in the presence of an inorganic alkali and a phase-transfer catalyst at temperatures from approximately ambient temperature down to below the boiling point of haloform to form 13-3 molecules in which R1, R2, R3, R4, R5, R6, R5, R7, R8 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

14. The process comprising formula c13-313-4 involves the conversion of cyclopropyl acetal 13-3 to the aldehyde 13-4 in a polar solvent in the presence of an aqueous mineral acid at ambient temperature where R1, R2, R3, R4, R5, R6, R5, R7, R8, and R9 satisfy claim 115. The process comprising formula d13-41-3 involves the oxidation of 13-4 in a polar aprotic solvent at temperatures ranging from approximately 0°C to approximately ambient temperature where R1, R2, R3, R4, Rs, R6, R7, R8, and R9 satisfy claim 115.R8 and R9 comply with claim 1------------------07 / 04 / 2016------(OCR)Page 1 of 19 pages. Claim 1. A molecule with the following formula in which:(A) R1 is chosen from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)calkyl,(C3-C6)cycloalkyl,(C2-C6)alkenyl,(C3C€6)cyclocalkenyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C,-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl L,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(0)(C1-C6)alkyl,S(0)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(B) R2 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkinil, (C3-C6) cycloalkinil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalky]-S(O)2NH2;(C)R3 were selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocyclocalkyl,(C2-C6)halocalkenil,(C3-C6)H Halocyclocalcinyl,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)halocalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,(C1-C6)calkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; Page 2 of 19 (D) R4 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkenil, (C3-C6) cycloalkenil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) halocycloalkyl, (C2-C6) haloalkinine. L,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(E) R5 was selected from the group containing H,F,Cl,Br,I,CN,NH2,N02,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,C(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil ,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(F) R6 was selected from the group containing H and (C1-C6) alkyls;(G) R7 was selected from the group containing H, F, Cl, Br and I;(H) R8 was selected from the group containing F, Cl, Br and I;(I) R9 was selected from the group containing H and (C1-C6) alkyls;(J) Q1 was selected from the group containing O and r;(K) Q2 was selected from the group containing O and r;(L) R10 was selected from the group containing H, (C1-C6) alkyls, (C2-C6) alkenyls, (C1-C6) haloalkyls, (C1-C6) alkyls, (C1-C6) alkoxys, C(=0)(C1-C6) alkyls and (C1-C6) alkoxys C(=0)(C1-C6) alkyls;(M) R11 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl.(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2; Page 3 of 19 pages (N) R12 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)alkoxy,(CrC6)haloalkyl,(C3-C6)haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl, (C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalkyl-S(O)2NH2;(O) X1 was selected from the group consisting of (7)N,(8)NO and (9)CR13 where R13 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2 and triazolyl;(P) X2 was selected from a group consisting of (7)N,(8)NO and (9)CR14, where R14 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl. Page 4 of 19(Q) X3 was selected from the group consisting of N(RIS)(replaced or unreplaced phenyls),N(R15)(substituted or unsubstituted heterocyclyls) and substituted or unsubstituted heterocyclyls(a) where such R15 is selected from a group consisting of H,(C1-C6)alkyl,(C2-c6)alkinyl,(C2-C6)alkinyl,(C1-C6)haloalkyl,(C1-C6)alkyl(C1-C6)alkoxy,C(=0)(C1-C6)alkyl and(C1-C6)alkoxyC(=0)(C1-C6)alkyl(b). where such substituted phenyls and substituted heterocyclyls with one or more substitutes selected from the group consisting of F,Cl,Br,I,H,CN,CHO,NHOH,NO,NO2,OH,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)alkylphenyl,(C1-C6)alkyl-S(0)2NH2,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkyl-S(O)2NH2,(C2-C6)alkinyl,(C2-C6)alkinyl ,(C2-C6)haloalkenil,(C3-C6)cycloalkenil,(C3-C6)cycloalkyl,(C3-C6)halocycloalkenil,(C3-C6)halocycloalkyl,(C1-C6)alkyl((C1-C6)alkyl)(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,C(O)(C1-C6)alkyl,C(O)NH(C1-C6)alkyl,C(O)NHphenyl,C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),imidazolyl,N((C1-C6)alkyl)(C(O)(C1-C6)alkyl),N((C1-C6)alkyl)(C(O)(C1-C6)alkyl-O(C1-C6)alkyl),N((C1-C6)alkyl)(C(0)(C1-C6)haloalkyl),N((C1-C6)alkyl)(C(O)O(C1-C6)alkyl),N((C1-C6)alkyl)2,N(C(O)O(C1-C6)alkyl)2,N=CH-phenyl,NH((C1-C6)alkylC(O)(C1-C6)alkyl),NH(C(0)(C1-C6)alkyl) ,NH(C(O)(C2-C6)alkinyl),NH(C(O)(C3-C6)cycloalkyl),NH(C1-C6)alkyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl1NH(CrC6)alkylphenyl,NH(S(O)2(C1-C6)alkyl),NH2,NHC(O)(C1-C6)alkyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)halo Alkyl,NHC(O)(C1-C6)alkinyl,NH-C(O)O(C1-C6)alkyl,oxazolyl,phenyl,pyrazolyl,pyridinyl,S(=NCN)((C1-C6)alkyl),S(C1-C6)alkyl,r(C1-C6)haloalkyl,S(O)(=NCN)((C1-C6)alkyl),S(O)(C1-C6)alkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)alkyl,S(O)2( C1-C6) Haloalkyl, SCN, Thiazolyl, Thienyl and Triazolyl, where alkoxy, alkyl, haloalkoxy, haloalkyl, alkenyl, alkinyl, haloalkenyl, cycloalkenyl, cycloalkyl, halocycloalkenyl, halocycloalkyl, imidazoyl, phenyl, pyrazolyl, pyridinyl, thiazoyl.Each thienyl and triazolyl may be alternatively replaced by one or more substitutes selected from the group consisting of F,Cl,Br,I,CN,OH,NH(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C,-C6)haloalkyl,NHCH2(C3-C6)cycloalkyl. Alkyl, NH2, NO2, oxo, (C1-C6)alkyl, (C1-C6)alkyl, (C1-C6c6)alkoxy and C(O)O-(C1-C6)alkyl; and N-oxides, agriculturally acceptable acid-added salts, salt derivatives, solvates, ester derivatives, crystal polymorphs, isotopes, isolated stereoisomers and tautomers of molecules with the formula one2. Molecules according to claim 1 where X3 is chosen from a group consisting of (1) formula, (2) formula, (3) formula, (4) formula, page 6 of 19 pages, (5) formula, (6) formula, (7) formula, (8) formula, (9) formula, (10) formula, (11) formula, page 7 of 19 pages, (12) formula, (13) formula, (14) formula, where: (a) R15 is chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl, (C1-C6) alkinyl, (C1-C6) haloalkyl, (C1-C6) alkyl, (C1-C6) alkoxy,C(=0)(C1-C6)alkyl and (C1-C6)alkoxy C(=O)(C1-C6)alkyl;(b) X4 was chosen from the group consisting of (i) N,(ii) NO and (iii) CR16 where R16 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halosy Colealkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl Page 8 of 19 of 19, in which each alkyl, cycloalkyl, alkynyl, cycloalkinyl, alkynyl, alkoxy, haloalkyl, halocycloalkyl, haloalkinyl, halocycloalkinyl and haloalkoxy may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)alkyl,(C1-C6)calkoxy and C(O)O-(C1-C6)alkyl;(c)Xs were selected from the group consisting of (i)N,(ii)NO and (iii)CR17 where R17 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)calkoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkinil,(C3- C6)halocycloalkenil,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,C(O)O(C1-C6)calkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)halocalkyl-S(O)2NH2;(d) selected from the group consisting of(i) N,(ii) NO and(iii) and CR18. Where R18 was selected from the group consisting of H,F,Cl,Br,I,CN,NO2,OH,NH2,SCN,CHO,(C1-C6)alkyl,(C2-C6)calkinil,(c2-c6)calkinil,(C1-C6)halocalkyl,(C1-C6)alkoxy,(C1-C6)halocalkoxy,NH(C1-C6)alkyl Alkyl,N((C1-C6)alkyl)2,S(C1-C6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl,CONH(C1-C6)alkyl,NHCO(C1-C6)alkyl,N(C1-C6)alkyl-CO(C1-C6)alkyl,NHCO(C2-C6)alkenyl,NHCO(C3-C6)cycloalkyl,NHCO(C1-C6)haloalkyl,N(C1-C6)alkyl-CO(C1-C6)haloalkyl,NHCO(C1-C6)alkylphenyl,NH-C(O)O(C1-C6)alkyl,N(C1-C6)alkyl-C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,phenyl,pyrazolyl,imidazolyl and triazolyl. Page 9 of the dictionary. Nineteen functional groups in which each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, halocycloalkyl, cyclocalkyl, phenyl, imidazolyl, and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, nh2, no2, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(O)O-(C1-C6)alkyl. (e) x7 was selected from a group consisting of (i)N,(ii)NO and (iii)CR19, where R19 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(CC1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,C(O)O(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (f) X8 was chosen from the group consisting of (i)N,(ii) NO and (iii) CR20 where R20 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,N02,(C1-C6 alkyl,(C3-C6)cycloalkyl, (C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloclcoxy,r(C1-C 6) alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,c(o)o(c1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (g) R21 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkenil,(C3-C6)halocycloalkenil,(C1-C6)halocalkenil,S(C1-c6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-c6)calkyl,S(C1-C6) page 10 of 19 pages of haloalkyl,S((O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)calcoxy and C(O)O-(C1-C6)alkyl(h). R22 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloclcoxy. ,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where alkyl,alkenyl,calkinyl,haloalkyl,alkoxy,haloclkoxy,phenyl,Each imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl(i). R23 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6). Halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C 6) Haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl,alkenyl,alkinyl,haloalkyl,alxoxy,haloalxoxy,phenyl,imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alxoxy and C(O)O-(C1-C6)alkyl(j) R24 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkyl,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkene Phenyl, pyridinyl and thienyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6haloalkyl-S(O)2NH2,phenyl, pyridinyl and thienyl Where each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, inidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group comprising F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl3. The molecule under claim 1 where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolyl, oxazolyl, pyrazinil, pyrazolil, pyridazinil, pyridyl, pyrimidinil, tetrazolyl, thiadiazolyl, thiazolyl, thienil, triazinil,[1,2,4] triazolo[1,[5-c]pyrimidinil, triazolil, 2,3-dihydrophthalazine-1,4-dionil, indolinil and pyrimidine-2,4(1H,3H / )-dionil, where the selected representatives were from the group comprising F,Cl,Br,I,H,CN,NH2,NO2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil and (C3-C6)halocycloalkyl4. The molecule according to claim 1, where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolinil, oxazolyl, pyridyl and thiadiazolyl, where such substitute is chosen from the group consisting of F, Cl, Br, I, H, CN, NO2, NH2, (C1-C6) alkoxy, (C1-C6) alkyl, (C1-C6) haloalkoxy, (C1-C6) haloalkyl, (C2-C6) haloalkenyl, (C3-C6) halocycloalkenyl and (C3-C6) halocycloalkyl5. The molecule according to claim 1 where X3 is N(R15)(substituted or unsubstituted phenyl)(a) where such R15fy is chosen from the group containing H and (C1-C6) alkyls(b) where such substituted phenyl has one or more representatives chosen from the group containing F,Cl,Br,I,CN,N02,NH2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6haloalkyl,(C2-C6)haloalkinyl,(C3-C6)cycloalkinyl,(C3-C6)cycloalkyl,(C3-C6)halocycloylkinyl and(C3-C6)halocycloalkyl. Page 12 of 19, page 6. The molecules according to claim 1 are (A) R1, R2, R3, R4, R5, R11 and R12 each freely chosen from the group consisting of H, F, Cl, Br, (C1-C6) alkyl, (C1-C6) haloalkyl and (C1-C6) haloalkoxy; (B) R6 and R9 are H; (C) R7 is chosen from the group consisting of C1 and Br; (D) R8 is chosen from the group consisting of C1 and Br; (E) Q1 and Q2 each freely chosen from the group consisting of O and S; (F) R10 is H; (G) x1 is chosen from the group consisting of; (4) N, (5) NO and (6) CR13 where R13 was chosen from a group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl and triazolyl;(H) x2 was chosen from a group consisting of (I)(3)N and (4). CR14 where R14 was chosen from a group consisting of H,F,C1 and(C1-C6)alkoxy;(I)X3 was chosen from a group consisting of (3)formula,(4)formula,Page 13 of 19 pages R15 where (h) R15 was chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl and (C1-C6) haloalkyl; (i) X4 was chosen from a group consisting of (i) N and (ii) CR16 where R16 was chosen from a group consisting of H, F, Cl, CN, NH2 and (C1-C6) alkyl; (j) Xs was chosen from a group consisting of (iv) N, (v) NO and (vi) CR17 where R17 was chosen from a group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from a group consisting of (iv) N, (v) NO and (vi) and CR18 where R18 was chosen from a group consisting of H, F, Cl, CN, NO2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6)alkyl,(C1-C6)haloalkyl,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,CONH(C1-C6)alkyl andNHCO(C1-C6)alkyl;(I) X7 is CR19 where R19 was chosen from the group consisting of H,NH2 and F; page 14 of 19 pages;(m)X8 is CR20 where R20 was chosen from the group consisting of H,F,Cl,NH2 and (C1-C6)alkyl; and(n)R21,R22,R23 andR24 are H7.molecules according to claim 1 where(A)R1 is H;(B) R2 was chosen from the group consisting of H,Cl,Br,(CrC6)alkyl and (C,-c6)haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C,-C6)alkyl,(C,-c6)haloalkyl and(C1-C6)haloalkoxy;(D) R4 was chosen from the group consisting of H,Cl,Br,(C1-C6)alkyl and(C1-C6)haloalkyl;(E)R5 was chosen from the group consisting of H and C1;(F)R6 is H;(G)R7 was chosen from the group consisting of C1 and Br;(H)R8 was chosen from the group consisting of C1 and Br;(I)R9 is H;(J)Q1 is 0;(K)(Q2 was chosen from the group consisting of O and S;(L)R10 is H;(M) R11 was selected from a group consisting of H,F,C1 and (C1-C6) alkyls; (N)R12 was selected from a group consisting of H and C1; (O)X1 was selected from a group consisting of (1)N,(2)NO and (3)CR13 where R13 was selected from a group consisting of H,F,Cl,Br,I,CN,(C1-C6) alkyls,(C1C6) alkoxy,(C1-C6) haloalkyls,(C1-C6) haloalkyls,S(C1-C6) alkyls,S(O)(C1-C6) alkyls,S(O)2(C1-C6) alkyls and triazolyls; page 15 of 19 pages. (P) X2 was selected from a group consisting of (1) N and (2) CR14, where R14 was chosen from a group consisting of H, F, C1 and (c1-c6) alkoxy; and (Q) X3 was chosen from a group consisting of (3) formulas, (4) formulas,(5) Formula and (6) Formula in which (h) R15 was chosen from the group consisting of H, (C1-C6) alkyl, (C1-C6) alkynyl and (C1-C6) haloalkyl; (i) X4 was chosen from the group consisting of (i) N and (ii) CR16 in which R16 was chosen from the group consisting of H, F, Cl, CN, NH and (C1-C6) alkyl. Page 16 of 19 pages. (j) X5 was chosen from the group consisting of (i) N, (ii) NO and (iii) CR17 in which R17 was chosen from the group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from the group consisting of (i) N, (ii) NO and (iii) (I) X7 is CR19, where R19 was chosen from the group consisting of H, NH2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy, (C1-C6) haloalkoxy, S(C1-C6) alkyl, S(O)(C1-C6) alkyl, S(O)2(C1-C6) alkyl, CONH(C1-C6) alkyl and NHCO(C1-C6) alkyl; (m) X8 is CR20, where R20 was chosen from the group consisting of H, F, Cl, NH2 and (C1-C6) alkyl; and (n) R21, R22, R23 and R24 are H8. The molecule according to claim 1 where:(A) R1 is chosen from a group consisting of H, F or C1;(B) R2 is chosen from a group consisting of H, F, Cl, Br,(C1-C6) alkyl and (C1-C6) haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C1-C6) alkyl,(C1-C6) haloalkyl and (C1-C6) haloalkoxy;(D) R4 was chosen from the group consisting of H,F,Cl,Br,(C1C6) alkyl and (C1-C6) haloalkyl;(E) R5 was chosen from the group consisting of H,F and C1;(F) R6 is H; page 17 of 19 pages;(G) R7 was chosen from the group consisting of C1 and Br;(H) R8 was chosen from the group consisting of C1 and Br;(I) R9 is H;(J) Q1 is O;(K) Q2 was chosen from the group consisting of O and S;(L) R10 is H;(M) R11 (N) R12 is chosen from the group consisting of H and C1; (O) X1 is CR13 where R13 is chosen from the group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; (P) X2 is CR14 where R4 is chosen from the group consisting of H,F,C1 and(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; and (Q) X3 is the formula where R15 is chosen from the group consisting of H,(C1-C6)alkyl,(C2-C6)alkenyl and (C1-C6)haloalkyl; X4 is CR16 where R16 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X5 is CR17 where R17 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X6 is CR18 where R18 .... 2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; page 18 of 19 pages X7 is CR19, where R19 was chosen from the group consisting of H,F,Cl,NH2CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; X8 is CR20, where R20 was chosen from the group consisting of H,F,Cl,CN,NH2NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; 9. A molecule pursuant to claim 1, which is selected from one of the following molecules: F1 to F249, F251 to F255, F257 to F268, F270 to F275, F277 to F320, F322 to F443, F445 to F465, F469, F471 to F488, F490 to F500, F502 to F506, F510, F511, F513 to F520, F524 to F532, F537 to F599.PF1, PF2, PF4 to PF22, PF24 to PF58, PF60, PF62, PF65, PF67 to PF78, PF102, PF104, PF107 to PF110, PF113 to PF119, PF122 to PF127, PF130, PF133 to PF136, PF138 to PF141, PF143, PF152, PF153, PF155, PF156, PF158, PF161 to PF164.

10. A composition consisting of one of the molecules under claims 1 to 9 and a carrier.

11. A process to control the pests, such process consisting of the application at the site with an effective pest-eliminating dose of one of the molecules under claims 1 to 10.

12. The process, which involves the formula 13-113-2, involves the reaction of molecule 13-1 with (C1-C6) alkyl orthoformates in the presence of acids with a pH between 0 and 5. This reaction is carried out in a (C1-C6) alkanol solvent at temperatures ranging from 0°C to ambient temperature and under ambient pressure to form molecule 13-2, in which R1, R2, R3, R4, R5,R6 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

13. The process, which includes page 19 of the formula b, formula 13-213-3, causes 13-2 to react with a carbine source such as haloform in the presence of an inorganic alkali and a phase-transfer catalyst at temperatures from approximately ambient temperature down to below the boiling point of haloform to form 13-3 molecules in which R1, R2, R3, R4, R5, R6, R5, R7, R8 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

14. The process comprising formula c13-313-4 involves the conversion of cyclopropyl acetal 13-3 to the aldehyde 13-4 in a polar solvent in the presence of an aqueous mineral acid at ambient temperature where R1, R2, R3, R4, R5, R6, R5, R7, R8, and R9 satisfy claim 115. The process comprising formula d13-41-3 involves the oxidation of 13-4 in a polar aprotic solvent at temperatures ranging from approximately 0°C to approximately ambient temperature where R1, R2, R3, R4, Rs, R6, R7, R8, and R9 satisfy claim 115.R8 and R9 satisfy claim 1------------Page 1 of 19 pages Claim 1. A molecule with the following formula in which:(A) R1 is chosen from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)calkyl,(C3-C6)cycloalkyl,(C2-C6)alkenyl,(C3C6)cyclocalkenyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C,-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl L,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(0)(C1-C6)alkyl,S(0)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2;(B) R2 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkinil, (C3-C6) cycloalkinil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalky]-S(O)2NH2;(C)R3 were selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocyclocalkyl,(C2-C6)halocalkenil,(C3-C6)H Halocyclocalcinyl,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)halocalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,(C1-C6)calkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; Page 2 of 19 (D) R4 was selected from the group consisting of H, F, Cl, Br, I, CN, NH2, NO2, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C2-C6) alkenil, (C3-C6) cycloalkenil, (C2-C6) alkinil, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C3-C6) halocycloalkyl, (C2-C6) haloalkinine. L,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(E) R5 was selected from the group containing H,F,Cl,Br,I,CN,NH2,N02,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,C(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil ,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2;(F) R6 was selected from the group containing H and (C1-C6) alkyls;(G) R7 was selected from the group containing H, F, Cl, Br and I;(H) R8 was selected from the group containing F, Cl, Br and I;(I) R9 was selected from the group containing H and (C1-C6) alkyls;(J) Q1 was selected from the group containing O and r;(K) Q2 was selected from the group containing O and r;(L) R10 was selected from the group containing H, (C1-C6) alkyls, (C2-C6) alkenyls, (C1-C6) haloalkyls, (C1-C6) alkyls, (C1-C6) alkoxys, C(=0)(C1-C6) alkyls and (C1-C6) alkoxys C(=0)(C1-C6) alkyls;(M) R11 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl.(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenyl,(C3-C6)halocycloalkenyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyd-S(O)2NH2; Page 3 of 19 pages (N) R12 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)alkoxy,(CrC6)haloalkyl,(C3-C6)haloxy. Haloalkyl,(C2-C6)haloalkinyl,(C3-C6)halocycloalkinyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl, (C1-C6)alkyl-S(O)2NH2 and (C1-C6)haloalkyl-S(O)2NH2;(O) X1 was selected from the group consisting of (7)N,(8)NO and (9)CR13 where R13 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2 and triazolyl;(P) X2 was selected from a group consisting of (7)N,(8)NO and (9)CR14, where R14 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl. Page 4 of 19(Q) X3 was selected from the group consisting of N(RIS)(replaced or unreplaced phenyls),N(R15)(substituted or unsubstituted heterocyclyls) and substituted or unsubstituted heterocyclyls(a) where such R15 is selected from a group consisting of H,(C1-C6)alkyl,(C2-c6)alkinyl,(C2-C6)alkinyl,(C1-C6)haloalkyl,(C1-C6)alkyl(C1-C6)alkoxy,C(=0)(C1-C6)alkyl and(C1-C6)alkoxyC(=0)(C1-C6)alkyl(b). where such substituted phenyls and substituted heterocyclyls with one or more substitutes selected from the group consisting of F,Cl,Br,I,H,CN,CHO,NHOH,NO,NO2,OH,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)alkylphenyl,(C1-C6)alkyl-S(0)2NH2,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkyl-S(O)2NH2,(C2-C6)alkinyl,(C2-C6)alkinyl ,(C2-C6)haloalkenil,(C3-C6)cycloalkenil,(C3-C6)cycloalkyl,(C3-C6)halocycloalkenil,(C3-C6)halocycloalkyl,(C1-C6)alkyl((C1-C6)alkyl)(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,C(O)(C1-C6)alkyl,C(O)NH(C1-C6)alkyl,C(O)NHphenyl,C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),imidazolyl,N((C1-C6)alkyl)(C(O)(C1-C6)alkyl),N((C1-C6)alkyl)(C(O)(C1-C6)alkyl-O(C1-C6)alkyl),N((C1-C6)alkyl)(C(0)(C1-C6)haloalkyl),N((C1-C6)alkyl)(C(O)O(C1-C6)alkyl),N((C1-C6)alkyl)2,N(C(O)O(C1-C6)alkyl)2,N=CH-phenyl,NH((C1-C6)alkylC(O)(C1-C6)alkyl),NH(C(0)(C1-C6)alkyl) ,NH(C(O)(C2-C6)alkinyl),NH(C(O)(C3-C6)cycloalkyl),NH(C1-C6)alkyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl,NH(C1-C6)alkinyl1NH(CrC6)alkylphenyl,NH(S(O)2(C1-C6)alkyl),NH2,NHC(O)(C1-C6)alkyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)alkylphenyl,NHC(O)(C1-C6)halo Alkyl,NHC(O)(C1-C6)alkinyl,NH-C(O)O(C1-C6)alkyl,oxazolyl,phenyl,pyrazolyl,pyridinyl,S(=NCN)((C1-C6)alkyl),S(C1-C6)alkyl,r(C1-C6)haloalkyl,S(O)(=NCN)((C1-C6)alkyl),S(O)(C1-C6)alkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)alkyl,S(O)2( C1-C6) Haloalkyl, SCN, Thiazolyl, Thienyl and Triazolyl, where alkoxy, alkyl, haloalkoxy, haloalkyl, alkenyl, alkinyl, haloalkenyl, cycloalkenyl, cycloalkyl, halocycloalkenyl, halocycloalkyl, imidazoyl, phenyl, pyrazolyl, pyridinyl, thiazoyl.Each thienyl and triazolyl may be alternatively replaced by one or more substitutes selected from the group consisting of F,Cl,Br,I,CN,OH,NH(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C1-C6)alkyl,NH(C3-C6)cycloalkyl,CH2O(C,-C6)haloalkyl,NHCH2(C3-C6)cycloalkyl. Alkyl, NH2, NO2, oxo, (C1-C6)alkyl, (C1-C6)alkyl, (C1-C6c6)alkoxy and C(O)O-(C1-C6)alkyl; and N-oxides, agriculturally acceptable acid-added salts, salt derivatives, solvates, ester derivatives, crystal polymorphs, isotopes, isolated stereoisomers and tautomers of molecules with the formula one2. Molecules according to claim 1 where X3 is chosen from a group consisting of (1) formula, (2) formula, (3) formula, (4) formula, page 6 of 19 pages, (5) formula, (6) formula, (7) formula, (8) formula, (9) formula, (10) formula, (11) formula, page 7 of 19 pages, (12) formula, (13) formula, (14) formula, where: (a) R15 is chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl, (C1-C6) alkinyl, (C1-C6) haloalkyl, (C1-C6) alkyl, (C1-C6) alkoxy,C(=0)(C1-C6)alkyl and (C1-C6)alkoxy C(=O)(C1-C6)alkyl;(b) X4 was chosen from the group consisting of (i) N,(ii) NO and (iii) CR16 where R16 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,CHO,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C,-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halosy Colealkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl Page 8 of 19 of 19, in which each alkyl, cycloalkyl, alkynyl, cycloalkinyl, alkynyl, alkoxy, haloalkyl, halocycloalkyl, haloalkinyl, halocycloalkinyl and haloalkoxy may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, NH2, NO2, oxo, (C1-C6)alkyl,(C1-C6)calkoxy and C(O)O-(C1-C6)alkyl;(c)Xs were selected from the group consisting of (i)N,(ii)NO and (iii)CR17 where R17 was selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)calkinil,(C1-C6)calkoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkinil,(C3- C6)halocycloalkenil,(C1-C6)halocalkoxy,S(C1-C6)calkyl,S(O)(C1-C6)calkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)halocalkyl,S(O)2(C1-C6)halocalkyl,C(O)O(C1-C6)calkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)halocalkyl-S(O)2NH2;(d) selected from the group consisting of(i) N,(ii) NO and(iii) and CR18. Where R18 was selected from the group consisting of H,F,Cl,Br,I,CN,NO2,OH,NH2,SCN,CHO,(C1-C6)alkyl,(C2-C6)calkinil,(c2-c6)calkinil,(C1-C6)halocalkyl,(C1-C6)alkoxy,(C1-C6)halocalkoxy,NH(C1-C6)alkyl Alkyl,N((C1-C6)alkyl)2,S(C1-C6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,CO(C1-C6)alkyl,CONH(C1-C6)alkyl,NHCO(C1-C6)alkyl,N(C1-C6)alkyl-CO(C1-C6)alkyl,NHCO(C2-C6)alkenyl,NHCO(C3-C6)cycloalkyl,NHCO(C1-C6)haloalkyl,N(C1-C6)alkyl-CO(C1-C6)haloalkyl,NHCO(C1-C6)alkylphenyl,NH-C(O)O(C1-C6)alkyl,N(C1-C6)alkyl-C(O)O(C1-C6)alkyl,CH(=NO(C1-C6)alkyl),C(=NO(C1-C6)alkyl)(C1-C6)alkyl,phenyl,pyrazolyl,imidazolyl and triazolyl. Page 9 of the dictionary. Nineteen functional groups in which each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, halocycloalkyl, cyclocalkyl, phenyl, imidazolyl, and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F, Cl, Br, I, CN, OH, nh2, no2, oxo, (C1-C6)alkyl, (C1-C6)alkoxy, and C(O)O-(C1-C6)alkyl. (e) x7 was selected from a group consisting of (i)N,(ii)NO and (iii)CR19, where R19 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(CC1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,C(O)O(C1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (f) X8 was chosen from the group consisting of (i)N,(ii) NO and (iii) CR20 where R20 was chosen from the group consisting of H,F,Cl,Br,I,CN,NH2,N02,(C1-C6 alkyl,(C3-C6)cycloalkyl, (C2-C6)alkinil,(C3-C6)cycloalkinil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkinil,(C3-C6)halocycloalkinil,(C1-C6)haloclcoxy,r(C1-C 6) alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,c(o)o(c1-C6)alkyl,(C1-C6)alkyl-S(O)2NH2 and(C1-C6)haloalkyl-S(O)2NH2; (g) R21 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)calkinil,(C1-C6)calcoxy,(C1-C6)halocalkyl,(C3-C6)halocycloalkyl,(C2-C6)halocalkenil,(C3-C6)halocycloalkenil,(C1-C6)halocalkenil,S(C1-c6)calkyl,S(O)(C1-C6)alkyl,S(O)2(C1-c6)calkyl,S(C1-C6) page 10 of 19 pages of haloalkyl,S((O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, imidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)calcoxy and C(O)O-(C1-C6)alkyl(h). R22 was selected from a group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6 alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloclcoxy. ,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)calkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where alkyl,alkenyl,calkinyl,haloalkyl,alkoxy,haloclkoxy,phenyl,Each imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl(i). R23 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkinyl,(C3-C6)cycloalkinyl,(C2-C6)alkinyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C3-C6). Halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C 6) Haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6)haloalkyl-S(O)2NH2,phenyl,pyridinyl and thienyl where each alkyl,alkenyl,alkinyl,haloalkyl,alxoxy,haloalxoxy,phenyl,imidazolyl and triazolyl may be alternatively replaced by one or more representatives selected from the group consisting of F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alxoxy and C(O)O-(C1-C6)alkyl(j) R24 is selected from the group consisting of H,F,Cl,Br,I,CN,NH2,NO2,(C1-C6)alkyl,(C3-C6)cycloalkyl,(C2-C6)alkenil,(C3-C6)cycloalkenil,(C2-C6)alkinil,(C1-C6)alkyl,(C1-C6)haloalkyl,(C3-C6)halocycloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkene Phenyl, pyridinyl and thienyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,S(C1-C6)haloalkyl,S(O)(C1-C6)haloalkyl,S(O)2(C1-C6)haloalkyl,(C1-C6)alkyl-S(O)2NH2,(C1-C6haloalkyl-S(O)2NH2,phenyl, pyridinyl and thienyl Where each alkyl, alkynyl, alkynyl, haloalkyl, alkoxy, haloalkoxy, phenyl, inidazolyl and triazolyl may be alternatively replaced by one or more representatives chosen from the group comprising F,Cl,Br,I,CN,OH,NH2,NO2,oxo,(C1-C6)alkyl,(C1-C6)alkoxy and C(O)O-(C1-C6)alkyl3. The molecule under claim 1 where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolyl, oxazolyl, pyrazinil, pyrazolil, pyridazinil, pyridyl, pyrimidinil, tetrazolyl, thiadiazolyl, thiazolyl, thienil, triazinil,[1,2,4] triazolo[1,[5-c]pyrimidinil, triazolil, 2,3-dihydrophthalazine-1,4-dionil, indolinil and pyrimidine-2,4(1H,3H / )-dionil, where the selected representatives were from the group comprising F,Cl,Br,I,H,CN,NH2,NO2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6)haloalkyl,(C2-C6)haloalkenil,(C3-C6)halocycloalkenil and (C3-C6)halocycloalkyl4. The molecule according to claim 1, where X3 is a substituted or unsubstituted heterocyclyl, where such heterocyclyl is chosen from the group consisting of indolinil, oxazolyl, pyridyl and thiadiazolyl, where such substitute is chosen from the group consisting of F, Cl, Br, I, H, CN, NO2, NH2, (C1-C6) alkoxy, (C1-C6) alkyl, (C1-C6) haloalkoxy, (C1-C6) haloalkyl, (C2-C6) haloalkenyl, (C3-C6) halocycloalkenyl and (C3-C6) halocycloalkyl5. The molecule according to claim 1 where X3 is N(R15)(substituted or unsubstituted phenyl)(a) where such R15fy is chosen from the group containing H and (C1-C6) alkyls(b) where such substituted phenyl has one or more representatives chosen from the group containing F,Cl,Br,I,CN,N02,NH2,(C1-C6)alkoxy,(C1-C6)alkyl,(C1-C6)haloalkoxy,(C1-C6haloalkyl,(C2-C6)haloalkinyl,(C3-C6)cycloalkinyl,(C3-C6)cycloalkyl,(C3-C6)halocycloylkinyl and(C3-C6)halocycloalkyl. Page 12 of 19, page 6. The molecules according to claim 1 are (A) R1, R2, R3, R4, R5, R11 and R12 each freely chosen from the group consisting of H, F, Cl, Br, (C1-C6) alkyl, (C1-C6) haloalkyl and (C1-C6) haloalkoxy; (B) R6 and R9 are H; (C) R7 is chosen from the group consisting of C1 and Br; (D) R8 is chosen from the group consisting of C1 and Br; (E) Q1 and Q2 each freely chosen from the group consisting of O and S; (F) R10 is H; (G) x1 is chosen from the group consisting of; (4) N, (5) NO and (6) CR13 where R13 was chosen from a group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl,(C1-C6)haloalkoxy,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl and triazolyl;(H) x2 was chosen from a group consisting of (I)(3)N and (4). CR14 where R14 was chosen from a group consisting of H,F,C1 and(C1-C6)alkoxy;(I)X3 was chosen from a group consisting of (3)formula,(4)formula,Page 13 of 19 pages R15 where (h) R15 was chosen from a group consisting of H, (C1-C6) alkyl, (C2-C6) alkenyl and (C1-C6) haloalkyl; (i) X4 was chosen from a group consisting of (i) N and (ii) CR16 where R16 was chosen from a group consisting of H, F, Cl, CN, NH2 and (C1-C6) alkyl; (j) Xs was chosen from a group consisting of (iv) N, (v) NO and (vi) CR17 where R17 was chosen from a group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from a group consisting of (iv) N, (v) NO and (vi) and CR18 where R18 was chosen from a group consisting of H, F, Cl, CN, NO2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6)alkyl,(C1-C6)haloalkyl,S(C1-C6)alkyl,S(O)(C1-C6)alkyl,S(O)2(C1-C6)alkyl,CONH(C1-C6)alkyl andNHCO(C1-C6)alkyl;(I) X7 is CR19 where R19 was chosen from the group consisting of H,NH2 and F; page 14 of 19 pages;(m)X8 is CR20 where R20 was chosen from the group consisting of H,F,Cl,NH2 and (C1-C6)alkyl; and(n)R21,R22,R23 andR24 are H7.molecules according to claim 1 where(A)R1 is H;(B) R2 was chosen from the group consisting of H,Cl,Br,(CrC6)alkyl and (C,-c6)haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C,-C6)alkyl,(C,-c6)haloalkyl and(C1-C6)haloalkoxy;(D) R4 was chosen from the group consisting of H,Cl,Br,(C1-C6)alkyl and(C1-C6)haloalkyl;(E)R5 was chosen from the group consisting of H and C1;(F)R6 is H;(G)R7 was chosen from the group consisting of C1 and Br;(H)R8 was chosen from the group consisting of C1 and Br;(I)R9 is H;(J)Q1 is 0;(K)(Q2 was chosen from the group consisting of O and S;(L)R10 is H;(M) R11 was selected from a group consisting of H,F,C1 and (C1-C6) alkyls; (N)R12 was selected from a group consisting of H and C1; (O)X1 was selected from a group consisting of (1)N,(2)NO and (3)CR13 where R13 was selected from a group consisting of H,F,Cl,Br,I,CN,(C1-C6) alkyls,(C1C6) alkoxy,(C1-C6) haloalkyls,(C1-C6) haloalkyls,S(C1-C6) alkyls,S(O)(C1-C6) alkyls,S(O)2(C1-C6) alkyls and triazolyls; page 15 of 19 pages. (P) X2 was selected from a group consisting of (1) N and (2) CR14, where R14 was chosen from a group consisting of H, F, C1 and (c1-c6) alkoxy; and (Q) X3 was chosen from a group consisting of (3) formulas, (4) formulas,(5) Formula and (6) Formula in which (h) R15 was chosen from the group consisting of H, (C1-C6) alkyl, (C1-C6) alkynyl and (C1-C6) haloalkyl; (i) X4 was chosen from the group consisting of (i) N and (ii) CR16 in which R16 was chosen from the group consisting of H, F, Cl, CN, NH and (C1-C6) alkyl. Page 16 of 19 pages. (j) X5 was chosen from the group consisting of (i) N, (ii) NO and (iii) CR17 in which R17 was chosen from the group consisting of H, F, Cl, NH2 and CN; (k) X6 was chosen from the group consisting of (i) N, (ii) NO and (iii) (I) X7 is CR19, where R19 was chosen from the group consisting of H, NH2, NH2, (C1-C6) alkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy, (C1-C6) haloalkoxy, S(C1-C6) alkyl, S(O)(C1-C6) alkyl, S(O)2(C1-C6) alkyl, CONH(C1-C6) alkyl and NHCO(C1-C6) alkyl; (m) X8 is CR20, where R20 was chosen from the group consisting of H, F, Cl, NH2 and (C1-C6) alkyl; and (n) R21, R22, R23 and R24 are H8. The molecule according to claim 1 where:(A) R1 is chosen from a group consisting of H, F or C1;(B) R2 is chosen from a group consisting of H, F, Cl, Br,(C1-C6) alkyl and (C1-C6) haloalkyl;(C) R3 was chosen from the group consisting of H,F,Cl,Br,(C1-C6) alkyl,(C1-C6) haloalkyl and (C1-C6) haloalkoxy;(D) R4 was chosen from the group consisting of H,F,Cl,Br,(C1C6) alkyl and (C1-C6) haloalkyl;(E) R5 was chosen from the group consisting of H,F and C1;(F) R6 is H; page 17 of 19 pages;(G) R7 was chosen from the group consisting of C1 and Br;(H) R8 was chosen from the group consisting of C1 and Br;(I) R9 is H;(J) Q1 is O;(K) Q2 was chosen from the group consisting of O and S;(L) R10 is H;(M) R11 (N) R12 is chosen from the group consisting of H and C1; (O) X1 is CR13 where R13 is chosen from the group consisting of H,F,Cl,Br,I,CN,(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; (P) X2 is CR14 where R4 is chosen from the group consisting of H,F,C1 and(C1-C6)alkyl,(C1-C6)alkoxy,(C1-C6)haloalkyl and(C1-C6)haloalkoxy; and (Q) X3 is the formula where R15 is chosen from the group consisting of H,(C1-C6)alkyl,(C2-C6)alkenyl and (C1-C6)haloalkyl; X4 is CR16 where R16 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X5 is CR17 where R17 was chosen from the group consisting of H,F,Cl,NH2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and (C1-C6)haloalkoxy; X6 is CR18 where R18 .... 2,CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; page 18 of 19 pages X7 is CR19, where R19 was chosen from the group consisting of H,F,Cl,NH2CN,NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; X8 is CR20, where R20 was chosen from the group consisting of H,F,Cl,CN,NH2NO2,(C1-C6)alkyl,(C1-C6)haloalkyl,(C1-C6)alkoxy and(C1-C6)haloalkoxy; 9. A molecule pursuant to claim 1, which is selected from one of the following molecules: F1 to F249, F251 to F255, F257 to F268, F270 to F275, F277 to F320, F322 to F443, F445 to F465, F469, F471 to F488, F490 to F500, F502 to F506, F510, F511, F513 to F520, F524 to F532, F537 to F599.PF1, PF2, PF4 to PF22, PF24 to PF58, PF60, PF62, PF65, PF67 to PF78, PF102, PF104, PF107 to PF110, PF113 to PF119, PF122 to PF127, PF130, PF133 to PF136, PF138 to PF141, PF143, PF152, PF153, PF155, PF156, PF158, PF161 to PF164.

10. A composition consisting of one of the molecules under claims 1 to 9 and a carrier.

11. A process to control the pests, such process consisting of the application at the site with an effective pest-eliminating dose of one of the molecules under claims 1 to 10.

12. The process, which involves the formula 13-113-2, involves the reaction of molecule 13-1 with (C1-C6) alkyl orthoformates in the presence of acids with a pH between 0 and 5. This reaction is carried out in a (C1-C6) alkanol solvent at temperatures ranging from 0°C to ambient temperature and under ambient pressure to form molecule 13-2, in which R1, R2, R3, R4, R5,R6 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

13. The process, which includes page 19 of the formula b, formula 13-213-3, causes 13-2 to react with a carbine source such as haloform in the presence of an inorganic alkali and a phase-transfer catalyst at temperatures from approximately ambient temperature down to below the boiling point of haloform to form 13-3 molecules in which R1, R2, R3, R4, R5, R6, R5, R7, R8 and R9 satisfy claim 1 and Ra is (C1-C6) alkyl.

14. The process comprising formula c13-313-4 involves the conversion of 13-3 cyclopropyl acetal 13-3 to the aldehyde 13-4 in a polar solvent in the presence of an aqueous mineral acid at ambient temperature where R1, R2, R3, R4, R5, R6, R5, R7, R8, and R9 satisfy claim 115. The process comprising formula d13-41-3 involves the oxidation of 13-4 in a polar aprotic solvent at temperatures ranging from approximately 0°C to approximately ambient temperature where R1, R2, R3, R4, Rs, R6, R7, R8, and R9 satisfy claim 115.