A diagnostic kit for immunoglobulin G (IMG) antibodies against the coronavirus.

Abstract

OCR 10KL (October 30, 2024) This invention relates to a diagnostic kit for detecting immunoglobulin G antibodies against the coronavirus. The test kit relies on viruses, including the novel coronavirus that causes the COVID-19 pandemic. The principles and techniques of specific binding and target separation using substrate chromatography, by... It uses biomolecules that are specific to immunoglobulin G antibodies against the virus, inducing binding. Specifically, in a sandwich format, it displays signals in the test result bar area along with the bar area. The control signal is expressed through connection with signaling molecules that indicate the presence of... The immunoglobulin G immune molecule against the novel coronavirus; this invention can be applied... Applications include monitoring the development of immunity among infected individuals in communities during and after epidemics. Furthermore, this information, from an epidemiological perspective, can be used for tracking and evaluation. Vaccine effectiveness

Claims

OCR 10KL (October 30, 2024) 1. The kit for detecting immunoglobulin G molecules against coronavirus consists of: A. Sample support material (1) for supporting the sample to be tested. b. Reactant storage material (2) for use in containing the reactant (21) which contains molecules Signals and biomolecules specific to type 1 sandwich immune molecules. Where the reagent (21) is the substance that interacts with the sandwich immune molecules. C. Reacting material (3) which is immobilized with a substance that binds to the second immune molecule. d. Test result signal bar (31) containing biomolecules specific to immune molecules. The second type of sandwich model, where immune molecules are sandwiched between biological molecules that contain... Specificity to type 1 immune molecules, which are bound to molecules that function in signaling processes. And biomolecules that are specific to type II sandwich immune molecules. Where the presence of immune molecules results in the appearance of signals on the signaling bar. Test results (31) C. Control signal display band (32) containing molecules specific to the reactant. It consists of signaling molecules and biomolecules that are specific to immune molecules. Sandwich type one C. Absorbent material (4) for the function of absorbing the remaining substances from the reaction to move from the support material. Example (1) Reactant storage material (2) Reactant material (3) Signal strip The test results (31) and the control signal bar (32) are shown, respectively. B. The reagent for analyzing the test kit serves to dissolve the components in the test kit so that they can be analyzed. Reactions are possible (6) Its unique characteristics are: Reactants (21) containing signaling molecules and biomolecules Specificity to type 1 sandwich immune molecules (detector molecules) where the molecule... The biological specificity of the type one sandwich immune molecule is a single-layer molecule (One layer) Biomolecules that are specific to type 1 sandwich immune molecules (Detector). A molecule that is a single-layer molecule is one that can be selected from any part of it. Or all of the protein; any part or all of the lipids; any part or all of the lipids. COVID-19 virus Biomolecules that are specific to the second type of sandwich immune molecule (Capture). (molecule) A selection can be made from any part or all of the antibody molecule. All of the molecules are capable of specifically binding to immunoglobulin G (GM) molecules. Molecules that are specific to the reactant can be selected from one or all of the following. Antibodies are molecules composed of proteins, in whole or in part, that are specific to a substance. The reaction involves avidin, streptavidin, nutravidin, and biotin. The reagents for the analysis kit consist of buffer solutions and ionizing agents. A solution, either individually or in combination with other solvents, having a specific acidity level. An alkaline solution between 7-10 is selected, from at least one type of phosphate tris. Tris chloride, borate, carbonate, and hepase are ionizing agents for the solution. At least one can be selected. One type of solvent, consisting of sodium and potassium salts, can be selected (at least one). Types derived from polysorbate, lauryl sulfate, cetyltrimethyl, colic acid, and glycosine.

2. A diagnostic kit for immunoglobulin G antibody molecules against coronavirus, as per claim 1, comprising: Additionally, a cartridge (5) containing the first part of the cartridge serves as a support for the assembly of Sample support material (1), Reactant storage material (2), Reactant material (3), and Adsorbent material (4). To assemble the test strip, the second part of the cassette consists of a window for receiving the sample. Place the sample onto the test strip (51) and the window for displaying the test results (52).

3. A kit for detecting immunoglobulin G antibody molecules against coronavirus, pursuant to claim 1. The biological specificity to such a type 1 sandwich immune molecule may be further enhanced with molecules. Double layer 4. A diagnostic kit for immunoglobulin G antibody molecules against coronavirus, pursuant to claim 3, whereby the molecule... Biologically specific to a double-layer sandwich immune molecular type I. As mentioned, a selection can be made from any part of the antibody molecule that specifically binds to that molecule. With regard to molecules composed of proteins, whether in whole or in part, and lipid biomolecules, in any part. One or all of the COVID-19 virus.

5. A diagnostic kit for immunoglobulin G antibodies against coronavirus, pursuant to claim 3 or 4, in which: Biomolecules that are specific to a double-layered, type I sandwich immune molecule. This layer is held in place by molecules that are specific to the biologically specific molecule. Specificity to type 1 sandwich immune molecules (detector molecules) results in two characteristics. The layer is then linked to signaling molecules (reporters), with a specific ratio between the biological molecules present. Specificity to type 1 sandwich immune molecules (detector molecules) and to molecules that have... Specificity to molecules that are specific to biological molecules that are specific to immune molecules. The first type of sandwich has a volume ratio of 10:1 to 1:

1.

6. A diagnostic kit for immunoglobulin G antibody molecules against coronavirus, pursuant to claim 1 or 2, in which: Biomolecules that are specific to type 1 sandwich immune molecules, and biomolecules that... The specificity to type II sandwich immunoglobulins is interchangeable.

7. A diagnostic kit for immunoglobulin G antibodies against coronavirus, pursuant to claim 1 or 2, in which: Signaling molecules can be selected from gold particles, silver particles, metal particles, platinum particles, etc. Copper, carbon particles, silica particles, iron particles, polymer particles, coloring agents—any one of them.

8. A diagnostic kit for immunoglobulin G antibody molecules against coronavirus, pursuant to claim 1 or 2, in which: The sample support material (1), the reagent storage material (2), and the absorbent material (4) are made from materials of choice from the available materials. Fiberglass, cotton fiber, synthetic polymers such as nylon, or derivatives of those materials, either individually or in combination. A combination of several things.

9. A diagnostic kit for immunoglobulin G antibodies against coronavirus, pursuant to claim 1 or 2, in which: Reacting material (3) is made from selectable materials from glass fiber, cotton fiber, cellulose, cellulose nitrate, etc. Synthetic polymers such as nylon, polyvinyl, polyether, and their derivatives, in one or more cases. Or a combination of several.

10. A diagnostic kit for immunoglobulin G antibody molecules against coronavirus, pursuant to claim 1 or 2, where: The ratio of the reagents for the analysis kit to the sample to be tested is in the range of 1:10 to 10:

1. By volume

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