A process for manufacturing a liquid wound dressing encapsulated with betel leaf extract for antibacterial purposes.

TH28451UActive Publication Date: 2026-07-02KING MONGKUTS UNIVERSITY OF TECHNOLOGY NORTH BANGKOK
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Patent Information

Application Number
TH2303002713
Authority / Receiving Office
TH · TH
Patent Type
Utility models
Current Assignee / Owner
Filing Date
2023-09-19
Publication Date
2026-07-02
Estimated Expiration
2029-09-18

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Abstract

------27 / 02 / 2026------(OCR) OCR 09WP The manufacturing process for a liquid wound dressing encapsulated with betel leaf extract for antibacterial properties involves the following steps: The first step is to extract the betel leaf extract by washing, drying, and grinding fresh betel leaves into a powder. This powder is then soaked in ethanol. The mixture is then heated and filtered using a vacuum system to obtain a betel leaf extract. The second step is to prepare the wound dressing material. Liquid type: Dissolve the polyvinyl butyral mixture in glycerin using ethanol as a solvent. Heat and reduce. The air bubbles are removed by vibration to create a liquid wound dressing, and the third step is preparing the liquid wound dressing. Encapsulate the betel leaf extract, mix the betel leaf extract into the prepared liquid wound dressing, heat and reduce. By vibrating the air bubbles, a liquid wound dressing material is created, encapsulating the betel leaf extract. This invention can be applied... It has medical applications in first aid, and also involves the application of Thai herbs in conjunction with it. Wound dressing materials that can help reduce the use of antibiotics, address the problem of antibiotic resistance in certain types of bacteria, and create... This adds value to Thai herbs and the country's economy. ------------
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Claims

------27 / 02 / 2026------(OCR) OCR 09WP 1. The manufacturing process for a liquid wound dressing encapsulated with betel leaf extract for antibacterial properties involves the following steps: A. Prepare the betel leaf extract by washing fresh betel leaves thoroughly and then drying them in a heat dryer. At a temperature of 60 degrees Celsius for 1 hour, it was ground into a powder using a mortar and pestle, and then the substances were extracted from it. Betel leaves were preserved using the maceration method in 75% ethanol, employing a specific ratio of betel leaf powder. The ratio of ethanol to ethanol is 1:175 by weight. Heat the mixture using a hotplate. (magnetic stirrer) at 70 degrees Celsius for 2 hours, then filtered using a filtration method. Vacuum extraction will yield betel leaf extract. B. Prepare a liquid polyvinyl butyral wound dressing mixed with glycerin, using ethanol as a solvent. A mixture of 15% by weight polyvinylbutyral and 1% by weight glycerin was used. Heat the substance using a hotplate magnetic stirrer to a temperature of 50 degrees Celsius. Stir at 400 rpm for 1 hour and 30 minutes, then allow the solution to reach a temperature of... The mixture is homogeneous and air bubbles are reduced by vibration under sound waves (sonication) at a frequency of 40 kilohertz. After 30 minutes, it will become a liquid wound dressing. C. Prepare a liquid wound dressing to encapsulate the betel leaf extract, using the liquid dressing obtained in step B. It consists of 15% by weight of polyvinylbutyral and 1% by weight of glycerin. Weigh the ingredients and mix with the betel leaf extract obtained from step A at a concentration of 0.5 grams per milliliter. Heat the mixture. A hotplate magnetic stirrer is used to stir a substance at a temperature of 50 degrees Celsius. At a speed of 400 revolutions per minute for 2 hours, then homogenize the solution and reduce it. Air bubbles are vibrated under sound waves at a frequency of 40 kHz for 30 minutes to obtain a wound dressing material. Liquid encapsulation of betel leaf extract. ------------